Danio rerio

0 known processes

cx43.4

connexin 43.4

(Aliases: cb232,wu:fc46h11,gjc1,gja7)

cx43.4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular metabolic process GO:0031323 320 0.542
regulation of response to stimulus GO:0048583 269 0.498
regulation of nucleic acid templated transcription GO:1903506 213 0.457
muscle structure development GO:0061061 196 0.451
Zebrafish
muscle tissue development GO:0060537 110 0.441
Zebrafish
biosynthetic process GO:0009058 294 0.420
alternative mrna splicing via spliceosome GO:0000380 1 0.413
epithelial cell morphogenesis GO:0003382 2 0.372
negative regulation of cellular process GO:0048523 283 0.351
regulation of mrna splicing via spliceosome GO:0048024 3 0.347
cellular biosynthetic process GO:0044249 286 0.318
response to oxygen containing compound GO:1901700 55 0.314
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.309
striated muscle cell differentiation GO:0051146 129 0.289
Zebrafish
regulation of mrna processing GO:0050684 3 0.289
regulation of signal transduction GO:0009966 225 0.264
muscle cell differentiation GO:0042692 139 0.261
Zebrafish
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.248
cell migration GO:0016477 237 0.248
heterocycle metabolic process GO:0046483 290 0.244
tube morphogenesis GO:0035239 349 0.238
muscle organ development GO:0007517 101 0.235
digestive system development GO:0055123 289 0.234
positive regulation of transport GO:0051050 2 0.232
regulation of stem cell differentiation GO:2000736 4 0.232
negative regulation of mrna processing GO:0050686 1 0.232
cellular aromatic compound metabolic process GO:0006725 295 0.231
cellular component biogenesis GO:0044085 178 0.227
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.221
regulation of nitrogen compound metabolic process GO:0051171 251 0.221
heart morphogenesis GO:0003007 156 0.220
epithelial cell development GO:0002064 42 0.214
digestive tract morphogenesis GO:0048546 231 0.212
embryonic heart tube development GO:0035050 133 0.207
Zebrafish
embryonic organ development GO:0048568 381 0.203
Zebrafish
locomotion GO:0040011 313 0.203
nucleobase containing compound metabolic process GO:0006139 274 0.198
cellular macromolecule metabolic process GO:0044260 391 0.197
regulation of cell communication GO:0010646 232 0.192
cell matrix adhesion GO:0007160 4 0.191
epithelial cell differentiation GO:0030855 116 0.190
determination of heart left right asymmetry GO:0061371 117 0.183
macromolecule biosynthetic process GO:0009059 227 0.181
regulation of intracellular protein transport GO:0033157 3 0.180
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.166
regulation of dna replication GO:0006275 3 0.161
cell surface receptor signaling pathway GO:0007166 325 0.157
establishment of localization GO:0051234 244 0.156
Zebrafish
stem cell maintenance GO:0019827 4 0.152
organic cyclic compound metabolic process GO:1901360 301 0.151
regulation of signaling GO:0023051 235 0.151
embryonic pattern specification GO:0009880 44 0.147
regulation of protein transport GO:0051223 3 0.146
regulation of macromolecule metabolic process GO:0060255 317 0.145
macromolecular complex subunit organization GO:0043933 74 0.144
organelle organization GO:0006996 227 0.137
Zebrafish
negative regulation of biological process GO:0048519 304 0.137
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.136
regulation of transcription dna templated GO:0006355 213 0.136
cellular macromolecule biosynthetic process GO:0034645 224 0.133
nitrogen compound metabolic process GO:0006807 319 0.132
maintenance of location GO:0051235 4 0.127
response to chemical GO:0042221 320 0.124
regulation of establishment of protein localization GO:0070201 4 0.123
gamete generation GO:0007276 33 0.120
cellular response to chemical stimulus GO:0070887 157 0.117
regulation of nucleocytoplasmic transport GO:0046822 2 0.117
epithelial tube morphogenesis GO:0060562 148 0.116
regulation of rna metabolic process GO:0051252 224 0.116
cellular amino acid metabolic process GO:0006520 7 0.114
negative regulation of rna splicing GO:0033119 1 0.113
cell substrate adhesion GO:0031589 4 0.112
blood vessel morphogenesis GO:0048514 216 0.112
single organism localization GO:1902578 225 0.112
Zebrafish
endoderm development GO:0007492 49 0.111
cellular response to prostaglandin stimulus GO:0071379 3 0.110
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.109
positive regulation of chromatin modification GO:1903310 1 0.109
determination of left right symmetry GO:0007368 179 0.109
mitotic cell cycle embryonic GO:0045448 2 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.109
single organism reproductive process GO:0044702 40 0.106
single organism organelle organization GO:1902589 199 0.103
Zebrafish
cell cycle process GO:0022402 53 0.103
spermatid development GO:0007286 2 0.103
regulation of rna biosynthetic process GO:2001141 213 0.096
cellular component movement GO:0006928 335 0.096
regulation of cell substrate adhesion GO:0010810 1 0.095
cellular localization GO:0051641 97 0.095
rna biosynthetic process GO:0032774 181 0.090
regulation of dna metabolic process GO:0051052 11 0.090
small molecule metabolic process GO:0044281 77 0.090
response to nutrient GO:0007584 3 0.089
organic cyclic compound biosynthetic process GO:1901362 223 0.088
vasculature development GO:0001944 278 0.087
regulation of meiotic cell cycle GO:0051445 1 0.087
embryonic limb morphogenesis GO:0030326 2 0.086
regulation of cellular biosynthetic process GO:0031326 245 0.086
regulation of multicellular organism growth GO:0040014 4 0.085
morphogenesis of an epithelium GO:0002009 333 0.082
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.082
regulation of cellular response to oxidative stress GO:1900407 2 0.082
positive regulation of cell cycle GO:0045787 3 0.081
larval development GO:0002164 2 0.081
regulation of histone deacetylation GO:0031063 2 0.081
determination of bilateral symmetry GO:0009855 204 0.080
neuroblast proliferation GO:0007405 2 0.080
mesenchymal cell development GO:0014031 78 0.079
regulation of biosynthetic process GO:0009889 250 0.078
regulation of multicellular organismal process GO:0051239 277 0.076
response to stress GO:0006950 263 0.076
Zebrafish
rna metabolic process GO:0016070 219 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.074
localization of cell GO:0051674 244 0.073
gene expression GO:0010467 252 0.072
regulation of cytoplasmic transport GO:1903649 4 0.072
positive regulation of dna metabolic process GO:0051054 1 0.071
cell motility GO:0048870 244 0.070
embryo development ending in birth or egg hatching GO:0009792 271 0.069
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.069
negative regulation of mrna metabolic process GO:1903312 3 0.069
regulation of cell cycle process GO:0010564 20 0.068
cell morphogenesis GO:0000902 289 0.067
mitotic cell cycle GO:0000278 64 0.067
stem cell development GO:0048864 82 0.066
spermatid differentiation GO:0048515 2 0.066
cell cycle g2 m phase transition GO:0044839 4 0.066
transcription dna templated GO:0006351 181 0.065
cell morphogenesis involved in differentiation GO:0000904 195 0.064
cellular ketone metabolic process GO:0042180 11 0.064
axis specification GO:0009798 43 0.063
negative regulation of gene expression GO:0010629 65 0.063
cell cycle g1 s phase transition GO:0044843 1 0.063
signal transduction GO:0007165 455 0.062
chordate embryonic development GO:0043009 271 0.062
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.062
regulation of organelle organization GO:0033043 29 0.062
embryonic heart tube morphogenesis GO:0003143 108 0.061
regulation of protein targeting GO:1903533 2 0.060
regulation of stem cell proliferation GO:0072091 2 0.059
neurological system process GO:0050877 62 0.058
Zebrafish
aging GO:0007568 2 0.058
system process GO:0003008 185 0.058
Zebrafish
lateral inhibition GO:0046331 1 0.058
transport GO:0006810 220 0.057
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.056
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.056
axonal fasciculation GO:0007413 11 0.056
single organism metabolic process GO:0044710 217 0.056
mitotic cell cycle process GO:1903047 48 0.055
organic substance biosynthetic process GO:1901576 289 0.055
regulation of primary metabolic process GO:0080090 311 0.054
death GO:0016265 121 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.053
head development GO:0060322 303 0.053
regulation of epithelial to mesenchymal transition GO:0010717 3 0.053
negative regulation of metabolic process GO:0009892 86 0.052
adherens junction organization GO:0034332 4 0.051
protein complex assembly GO:0006461 30 0.051
embryonic organ morphogenesis GO:0048562 274 0.051
Zebrafish
regulation of gene expression GO:0010468 265 0.050
stem cell proliferation GO:0072089 4 0.050
positive regulation of chromosome organization GO:2001252 1 0.050
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.050
positive regulation of cellular catabolic process GO:0031331 3 0.050
mesenchyme development GO:0060485 127 0.049
cellular amine metabolic process GO:0044106 2 0.048
single organism nuclear import GO:1902593 3 0.048
cell cycle GO:0007049 93 0.048
regulation of protein localization to nucleus GO:1900180 2 0.048
cell projection morphogenesis GO:0048858 244 0.047
negative regulation of macromolecule metabolic process GO:0010605 76 0.047
dna metabolic process GO:0006259 27 0.047
specification of axis polarity GO:0065001 4 0.046
negative regulation of dna replication GO:0008156 2 0.046
skeletal system development GO:0001501 181 0.046
Zebrafish
negative regulation of protein metabolic process GO:0051248 16 0.046
specification of symmetry GO:0009799 204 0.045
negative regulation of cell communication GO:0010648 96 0.045
nephron tubule morphogenesis GO:0072078 1 0.045
multicellular organism growth GO:0035264 4 0.044
regulation of mitotic cell cycle embryonic GO:0009794 2 0.042
protein import GO:0017038 3 0.042
neuron projection guidance GO:0097485 86 0.041
response to hydrogen peroxide GO:0042542 3 0.041
regulation of intracellular signal transduction GO:1902531 57 0.041
response to inorganic substance GO:0010035 38 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.040
regulation of apoptotic process GO:0042981 98 0.040
regulation of protein import into nucleus GO:0042306 2 0.040
urogenital system development GO:0001655 97 0.040
positive regulation of biological process GO:0048518 253 0.040
carboxylic acid metabolic process GO:0019752 22 0.039
negative regulation of developmental process GO:0051093 65 0.039
response to abiotic stimulus GO:0009628 122 0.039
protein import into nucleus GO:0006606 3 0.039
appendage development GO:0048736 80 0.038
Zebrafish
cellular protein metabolic process GO:0044267 129 0.038
regulation of cellular ketone metabolic process GO:0010565 7 0.038
negative regulation of rna metabolic process GO:0051253 48 0.038
multi organism process GO:0051704 134 0.038
programmed cell death GO:0012501 119 0.038
neural crest cell development GO:0014032 62 0.038
g2 m transition of mitotic cell cycle GO:0000086 4 0.037
adherens junction assembly GO:0034333 1 0.037
nucleocytoplasmic transport GO:0006913 4 0.036
keratinocyte differentiation GO:0030216 0 0.036
establishment of protein localization to organelle GO:0072594 4 0.035
oxoacid metabolic process GO:0043436 31 0.035
organelle assembly GO:0070925 110 0.035
Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
stem cell division GO:0017145 1 0.035
digestive tract development GO:0048565 265 0.035
regulation of oxidative stress induced cell death GO:1903201 2 0.035
heart looping GO:0001947 94 0.035
negative regulation of signal transduction GO:0009968 94 0.034
protein localization to nucleus GO:0034504 3 0.034
negative regulation of muscle cell differentiation GO:0051148 1 0.034
positive regulation of gtpase activity GO:0043547 1 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
liver development GO:0001889 96 0.034
sexual reproduction GO:0019953 36 0.034
cell projection organization GO:0030030 284 0.033
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.033
response to wounding GO:0009611 116 0.033
Zebrafish
cell junction organization GO:0034330 11 0.033
nephron tubule epithelial cell differentiation GO:0072160 1 0.033
striated muscle tissue development GO:0014706 110 0.033
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.033
cellular protein modification process GO:0006464 100 0.033
rna localization GO:0006403 4 0.032
chemotaxis GO:0006935 104 0.032
canonical wnt signaling pathway GO:0060070 48 0.032
3 utr mediated mrna stabilization GO:0070935 3 0.032
cell death GO:0008219 121 0.032
negative regulation of cell differentiation GO:0045596 46 0.031
single organism biosynthetic process GO:0044711 71 0.031
hepaticobiliary system development GO:0061008 98 0.031
negative regulation of protein kinase activity GO:0006469 4 0.031
cellular macromolecule localization GO:0070727 21 0.031
negative regulation of signaling GO:0023057 96 0.031
cell death in response to oxidative stress GO:0036473 2 0.031
amine metabolic process GO:0009308 2 0.031
ameboidal type cell migration GO:0001667 143 0.030
cellular component assembly GO:0022607 170 0.030
Zebrafish
somite development GO:0061053 96 0.030
branching morphogenesis of an epithelial tube GO:0048754 15 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
cellular response to radiation GO:0071478 4 0.030
protein complex biogenesis GO:0070271 30 0.030
neuron recognition GO:0008038 18 0.030
macromolecular complex assembly GO:0065003 35 0.030
regulation of metabolic process GO:0019222 359 0.030
negative regulation of cellular biosynthetic process GO:0031327 55 0.030
negative regulation of kinase activity GO:0033673 4 0.030
dna biosynthetic process GO:0071897 3 0.030
nuclear transport GO:0051169 4 0.029
ossification GO:0001503 23 0.029
cell division GO:0051301 20 0.029
apical junction assembly GO:0043297 1 0.028
mitotic dna integrity checkpoint GO:0044774 4 0.028
neuron differentiation GO:0030182 353 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
camera type eye development GO:0043010 222 0.027
response to ketone GO:1901654 1 0.027
single organism cell adhesion GO:0098602 29 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.027
actin cytoskeleton organization GO:0030036 63 0.027
Zebrafish
cellular component disassembly GO:0022411 1 0.026
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.026
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
protein targeting to nucleus GO:0044744 3 0.026
cell substrate junction assembly GO:0007044 2 0.026
regulation of establishment of planar polarity GO:0090175 4 0.026
cellular component morphogenesis GO:0032989 336 0.026
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.026
developmental process involved in reproduction GO:0003006 27 0.025
negative regulation of biosynthetic process GO:0009890 55 0.025
somatic stem cell maintenance GO:0035019 1 0.025
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
regulation of cell cycle GO:0051726 52 0.024
regulation of growth GO:0040008 42 0.024
macromolecule localization GO:0033036 54 0.024
segmentation GO:0035282 97 0.024
body morphogenesis GO:0010171 16 0.024
cognition GO:0050890 1 0.024
tissue remodeling GO:0048771 4 0.024
protein complex subunit organization GO:0071822 46 0.024
negative regulation of nucleic acid templated transcription GO:1903507 45 0.023
heart development GO:0007507 313 0.023
Zebrafish
cell substrate adherens junction assembly GO:0007045 1 0.023
cardiac atrium development GO:0003230 4 0.023
eye morphogenesis GO:0048592 144 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
cytosolic calcium ion transport GO:0060401 3 0.022
sister chromatid cohesion GO:0007062 2 0.022
germ cell development GO:0007281 22 0.022
positive regulation of catabolic process GO:0009896 4 0.022
response to organic substance GO:0010033 153 0.022
reproduction GO:0000003 40 0.021
lens fiber cell morphogenesis GO:0070309 3 0.021
regulation of mrna metabolic process GO:1903311 6 0.021
generation of neurons GO:0048699 385 0.021
nuclear import GO:0051170 3 0.021
lens fiber cell development GO:0070307 3 0.021
neuron projection morphogenesis GO:0048812 161 0.021
regulation of cellular component organization GO:0051128 86 0.021
regulation of developmental process GO:0050793 247 0.021
cilium assembly GO:0042384 58 0.020
actin filament based process GO:0030029 64 0.020
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.020
negative regulation of dna metabolic process GO:0051053 4 0.019
bone remodeling GO:0046849 2 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
endoderm formation GO:0001706 29 0.019
release of sequestered calcium ion into cytosol GO:0051209 3 0.019
sensory organ development GO:0007423 393 0.019
Zebrafish
regulation of response to oxidative stress GO:1902882 2 0.019
regulation of transport GO:0051049 45 0.019
Zebrafish
muscle cell development GO:0055001 115 0.019
Zebrafish
phagocytosis GO:0006909 3 0.018
negative regulation of stem cell differentiation GO:2000737 2 0.018
stem cell differentiation GO:0048863 117 0.018
response to endogenous stimulus GO:0009719 83 0.018
single organism transport GO:0044765 206 0.018
Zebrafish
response to other organism GO:0051707 97 0.018
protein modification process GO:0036211 100 0.018
gland development GO:0048732 143 0.018
regulation of multicellular organismal development GO:2000026 223 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
blood vessel development GO:0001568 246 0.017
growth GO:0040007 174 0.017
Zebrafish
response to metal ion GO:0010038 34 0.017
positive regulation of histone deacetylation GO:0031065 1 0.017
gastrulation GO:0007369 208 0.017
fat soluble vitamin biosynthetic process GO:0042362 2 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
proximal distal pattern formation GO:0009954 1 0.017
renal system development GO:0072001 94 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
Zebrafish
protein metabolic process GO:0019538 183 0.017
response to glucocorticoid GO:0051384 1 0.017
positive regulation of cell differentiation GO:0045597 30 0.016
regulation of organ morphogenesis GO:2000027 35 0.016
neuron development GO:0048666 262 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
neuron projection development GO:0031175 180 0.016
regulation of embryonic development GO:0045995 47 0.016
sulfur compound biosynthetic process GO:0044272 9 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
oogenesis GO:0048477 14 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
apoptotic process GO:0006915 116 0.016
hindbrain development GO:0030902 91 0.016
multicellular organismal signaling GO:0035637 22 0.016
detection of temperature stimulus GO:0016048 0 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
meiotic nuclear division GO:0007126 4 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
rna stabilization GO:0043489 4 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
transmission of nerve impulse GO:0019226 19 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regionalization GO:0003002 274 0.015
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.015
negative regulation of cellular protein metabolic process GO:0032269 16 0.015
positive regulation of histone modification GO:0031058 1 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of reproductive process GO:2000241 4 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
ras protein signal transduction GO:0007265 7 0.015
morphogenesis of a branching epithelium GO:0061138 16 0.015
chromosome organization GO:0051276 31 0.015
regulation of cell division GO:0051302 12 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.014
rna export from nucleus GO:0006405 1 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.014
regulation of catenin import into nucleus GO:0035412 2 0.014
macromolecular complex disassembly GO:0032984 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of cellular component movement GO:0051270 55 0.014
cardiac muscle tissue development GO:0048738 48 0.014
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
catenin import into nucleus GO:0035411 2 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
cell chemotaxis GO:0060326 17 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
regulation of nuclear division GO:0051783 9 0.014
macromolecule modification GO:0043412 111 0.014
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
endothelial cell development GO:0001885 12 0.014
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.013
myofibril assembly GO:0030239 48 0.013
Zebrafish
positive regulation of translation GO:0045727 1 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.013
regulation of biological quality GO:0065008 263 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of protein binding GO:0043393 3 0.013
response to vitamin GO:0033273 3 0.013
regulation of anatomical structure size GO:0090066 33 0.013
cellular response to retinoic acid GO:0071300 1 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
blood circulation GO:0008015 87 0.013
angiogenesis GO:0001525 158 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
spermatogenesis GO:0007283 7 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of intracellular ph GO:0051453 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
kidney epithelium development GO:0072073 23 0.013
developmental growth GO:0048589 166 0.013
Zebrafish
neural crest cell differentiation GO:0014033 72 0.013
ion homeostasis GO:0050801 41 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
cell aggregation GO:0098743 3 0.013
endothelial cell morphogenesis GO:0001886 1 0.013
neural precursor cell proliferation GO:0061351 20 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
regulation of cell death GO:0010941 103 0.013
protein acetylation GO:0006473 2 0.012
mesodermal cell migration GO:0008078 12 0.012
regulation of apoptotic signaling pathway GO:2001233 12 0.012
cytoskeleton organization GO:0007010 96 0.012
Zebrafish
negative regulation of epithelial cell differentiation GO:0030857 2 0.012
meiotic spindle organization GO:0000212 1 0.012
axonogenesis GO:0007409 152 0.012
response to lipid GO:0033993 60 0.012
wound healing GO:0042060 90 0.012
Zebrafish
positive regulation of protein metabolic process GO:0051247 23 0.012
response to external biotic stimulus GO:0043207 97 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
response to mercury ion GO:0046689 1 0.012
multi organism reproductive process GO:0044703 36 0.011
neural tube patterning GO:0021532 33 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
nucleic acid transport GO:0050657 2 0.011
segment specification GO:0007379 12 0.011
primary neural tube formation GO:0014020 1 0.011
sex determination GO:0007530 1 0.011
kidney development GO:0001822 92 0.011
epidermal cell differentiation GO:0009913 36 0.011
establishment of endothelial blood brain barrier GO:0014045 2 0.011
skeletal system morphogenesis GO:0048705 102 0.011
Zebrafish
head morphogenesis GO:0060323 8 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
posttranscriptional regulation of gene expression GO:0010608 14 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
intracellular signal transduction GO:0035556 85 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of collateral sprouting GO:0048670 7 0.011
cilium morphogenesis GO:0060271 85 0.011
cell cycle arrest GO:0007050 1 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
renal tubule morphogenesis GO:0061333 1 0.011
nephron epithelium development GO:0072009 16 0.011
regulation of cell shape GO:0008360 1 0.010
negative regulation of oxidative stress induced cell death GO:1903202 2 0.010
chemosensory behavior GO:0007635 1 0.010
patterning of lymph vessels GO:0060854 1 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
cell junction assembly GO:0034329 7 0.010
organic acid metabolic process GO:0006082 31 0.010
skeletal muscle tissue development GO:0007519 67 0.010
cell projection assembly GO:0030031 64 0.010
intrinsic apoptotic signaling pathway GO:0097193 20 0.010
negative regulation of multi organism process GO:0043901 3 0.010

cx43.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
physical disorder DOID:0080015 0 0.024
nervous system disease DOID:863 0 0.018
colon carcinoma DOID:1520 0 0.015
large intestine cancer DOID:5672 0 0.015
colon cancer DOID:219 0 0.015
gastrointestinal system cancer DOID:3119 0 0.015
intestinal cancer DOID:10155 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
colorectal cancer DOID:9256 0 0.015
disease of mental health DOID:150 0 0.012
developmental disorder of mental health DOID:0060037 0 0.012