Danio rerio

120 known processes

mc4r

melanocortin 4 receptor

(Aliases: si:dkey-151m6.62,zMC4)

mc4r biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of camp biosynthetic process GO:0030817 9 0.994
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.991
regulation of camp metabolic process GO:0030814 9 0.991
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.990
camp biosynthetic process GO:0006171 11 0.966
purine ribonucleotide biosynthetic process GO:0009152 20 0.953
ribose phosphate biosynthetic process GO:0046390 20 0.951
positive regulation of camp biosynthetic process GO:0030819 2 0.944
camp metabolic process GO:0046058 11 0.942
nucleotide biosynthetic process GO:0009165 21 0.938
cyclic nucleotide metabolic process GO:0009187 18 0.910
regulation of nucleotide biosynthetic process GO:0030808 15 0.908
circadian sleep wake cycle GO:0042745 2 0.889
cyclic purine nucleotide metabolic process GO:0052652 18 0.870
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.835
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.834
energy reserve metabolic process GO:0006112 2 0.787
negative regulation of camp biosynthetic process GO:0030818 7 0.759
ribonucleotide biosynthetic process GO:0009260 20 0.727
carbohydrate derivative metabolic process GO:1901135 61 0.687
heterocycle biosynthetic process GO:0018130 215 0.683
purine nucleotide biosynthetic process GO:0006164 20 0.666
regulation of cellular biosynthetic process GO:0031326 245 0.662
cyclic nucleotide biosynthetic process GO:0009190 18 0.646
negative regulation of nucleotide metabolic process GO:0045980 7 0.646
positive regulation of camp metabolic process GO:0030816 2 0.633
organic substance biosynthetic process GO:1901576 289 0.629
organophosphate biosynthetic process GO:0090407 23 0.626
g protein coupled receptor signaling pathway GO:0007186 74 0.591
negative regulation of camp metabolic process GO:0030815 7 0.590
nucleobase containing compound metabolic process GO:0006139 274 0.578
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.571
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.547
carbohydrate derivative biosynthetic process GO:1901137 43 0.529
organic cyclic compound metabolic process GO:1901360 301 0.520
regulation of response to stimulus GO:0048583 269 0.515
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.510
cellular biosynthetic process GO:0044249 286 0.496
regulation of cellular metabolic process GO:0031323 320 0.494
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.475
regulation of metabolic process GO:0019222 359 0.451
cellular nitrogen compound biosynthetic process GO:0044271 218 0.444
heterocycle metabolic process GO:0046483 290 0.442
nucleobase containing small molecule metabolic process GO:0055086 32 0.438
cognition GO:0050890 1 0.435
negative regulation of purine nucleotide metabolic process GO:1900543 7 0.433
nitrogen compound metabolic process GO:0006807 319 0.411
macromolecule biosynthetic process GO:0009059 227 0.409
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.407
positive regulation of biological process GO:0048518 253 0.402
purine containing compound biosynthetic process GO:0072522 20 0.374
negative regulation of biological process GO:0048519 304 0.361
response to light stimulus GO:0009416 46 0.360
single organism transport GO:0044765 206 0.356
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.350
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.344
circadian sleep wake cycle sleep GO:0050802 1 0.344
circadian sleep wake cycle process GO:0022410 2 0.340
cellular calcium ion homeostasis GO:0006874 13 0.338
single organism biosynthetic process GO:0044711 71 0.336
nucleoside phosphate biosynthetic process GO:1901293 21 0.323
system process GO:0003008 185 0.322
diencephalon development GO:0021536 58 0.322
regulation of multicellular organismal process GO:0051239 277 0.320
Human Mouse Rat
response to alkaloid GO:0043279 2 0.315
generation of neurons GO:0048699 385 0.314
divalent inorganic cation homeostasis GO:0072507 22 0.308
locomotion GO:0040011 313 0.308
negative regulation of cellular process GO:0048523 283 0.297
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.294
regulation of biosynthetic process GO:0009889 250 0.291
regulation of primary metabolic process GO:0080090 311 0.284
negative regulation of feeding behavior GO:2000252 2 0.281
nucleotide metabolic process GO:0009117 28 0.280
cellular aromatic compound metabolic process GO:0006725 295 0.278
cation homeostasis GO:0055080 33 0.277
sequestering of calcium ion GO:0051208 3 0.274
metal ion homeostasis GO:0055065 26 0.273
negative regulation of purine nucleotide biosynthetic process GO:1900372 7 0.272
regulation of blood pressure GO:0008217 1 0.272
homeostatic process GO:0042592 142 0.264
localization of cell GO:0051674 244 0.264
calcium ion homeostasis GO:0055074 19 0.263
rna metabolic process GO:0016070 219 0.259
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.250
purine nucleotide metabolic process GO:0006163 27 0.243
regulation of nitrogen compound metabolic process GO:0051171 251 0.240
response to chemical GO:0042221 320 0.232
Mouse
biosynthetic process GO:0009058 294 0.229
ribose phosphate metabolic process GO:0019693 27 0.226
establishment of localization GO:0051234 244 0.224
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.218
single organism localization GO:1902578 225 0.211
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.211
small molecule metabolic process GO:0044281 77 0.208
regulation of sequestering of calcium ion GO:0051282 4 0.206
cellular macromolecule metabolic process GO:0044260 391 0.204
organic cyclic compound biosynthetic process GO:1901362 223 0.195
aromatic compound biosynthetic process GO:0019438 217 0.192
regulation of localization GO:0032879 104 0.192
regulation of systemic arterial blood pressure GO:0003073 1 0.191
negative regulation of behavior GO:0048521 6 0.189
regulation of neurological system process GO:0031644 2 0.185
nucleobase containing compound biosynthetic process GO:0034654 205 0.185
sensory perception of chemical stimulus GO:0007606 3 0.185
response to oxygen containing compound GO:1901700 55 0.178
Mouse
purine containing compound metabolic process GO:0072521 29 0.175
cell morphogenesis involved in differentiation GO:0000904 195 0.174
cell migration GO:0016477 237 0.174
regulation of multicellular organismal development GO:2000026 223 0.173
response to food GO:0032094 1 0.173
regulation of biological quality GO:0065008 263 0.170
nucleoside phosphate metabolic process GO:0006753 28 0.163
regulation of adenylate cyclase activity GO:0045761 6 0.162
ion homeostasis GO:0050801 41 0.160
neuron projection morphogenesis GO:0048812 161 0.160
signal transduction GO:0007165 455 0.156
regulation of heart rate GO:0002027 5 0.156
cellular component movement GO:0006928 335 0.154
synaptic transmission GO:0007268 35 0.153
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 47 0.152
regulation of system process GO:0044057 40 0.151
cell part morphogenesis GO:0032990 246 0.148
multicellular organismal homeostasis GO:0048871 29 0.147
response to external stimulus GO:0009605 264 0.142
Rat
multicellular organismal water homeostasis GO:0050891 1 0.141
cell projection organization GO:0030030 284 0.141
cell motility GO:0048870 244 0.135
intracellular signal transduction GO:0035556 85 0.131
regulation of circadian sleep wake cycle GO:0042749 1 0.130
sodium ion homeostasis GO:0055078 3 0.129
regulation of multicellular organism growth GO:0040014 4 0.128
positive regulation of signaling GO:0023056 56 0.127
regulation of blood circulation GO:1903522 32 0.126
purine ribonucleotide metabolic process GO:0009150 27 0.126
chemical homeostasis GO:0048878 49 0.125
cellular component assembly GO:0022607 170 0.124
ribonucleotide metabolic process GO:0009259 27 0.124
regulation of signal transduction GO:0009966 225 0.123
aging GO:0007568 2 0.122
sensory organ development GO:0007423 393 0.122
positive regulation of transport GO:0051050 2 0.117
cell morphogenesis GO:0000902 289 0.116
positive regulation of cellular biosynthetic process GO:0031328 68 0.115
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.115
regulation of purine nucleotide metabolic process GO:1900542 17 0.114
multicellular organism growth GO:0035264 4 0.114
phosphorus metabolic process GO:0006793 109 0.109
opioid receptor signaling pathway GO:0038003 3 0.106
release of sequestered calcium ion into cytosol GO:0051209 3 0.103
chemosensory behavior GO:0007635 1 0.100
single organism metabolic process GO:0044710 217 0.099
negative regulation of cell death GO:0060548 60 0.099
ear development GO:0043583 127 0.098
transcription dna templated GO:0006351 181 0.098
response to endogenous stimulus GO:0009719 83 0.097
Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.094
programmed cell death GO:0012501 119 0.093
sensory organ morphogenesis GO:0090596 200 0.093
ion transport GO:0006811 114 0.093
response to inorganic substance GO:0010035 38 0.093
negative regulation of metabolic process GO:0009892 86 0.090
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.089
gene expression GO:0010467 252 0.089
adult behavior GO:0030534 2 0.089
female sex differentiation GO:0046660 4 0.089
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.087
eye development GO:0001654 277 0.086
cell projection morphogenesis GO:0048858 244 0.085
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.084
cell migration involved in gastrulation GO:0042074 79 0.084
neuropeptide signaling pathway GO:0007218 11 0.084
Zebrafish
organophosphate metabolic process GO:0019637 37 0.084
energy homeostasis GO:0097009 3 0.083
positive regulation of biosynthetic process GO:0009891 68 0.083
regulation of signaling GO:0023051 235 0.082
gabaergic neuron differentiation GO:0097154 2 0.081
regulation of macromolecule metabolic process GO:0060255 317 0.080
positive regulation of cellular process GO:0048522 201 0.079
positive regulation of macromolecule metabolic process GO:0010604 93 0.076
negative regulation of adenylate cyclase activity GO:0007194 6 0.075
pigmentation GO:0043473 85 0.074
nucleic acid metabolic process GO:0090304 244 0.074
connective tissue development GO:0061448 99 0.072
response to abiotic stimulus GO:0009628 122 0.072
regulation of cellular component organization GO:0051128 86 0.072
regulation of behavior GO:0050795 24 0.071
central nervous system development GO:0007417 387 0.071
cell death GO:0008219 121 0.071
regulation of developmental process GO:0050793 247 0.071
cellular component morphogenesis GO:0032989 336 0.071
sequestering of metal ion GO:0051238 3 0.070
regulation of metal ion transport GO:0010959 4 0.070
regulation of nucleotide metabolic process GO:0006140 17 0.068
phosphate containing compound metabolic process GO:0006796 108 0.068
endocrine system development GO:0035270 65 0.067
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.067
sleep GO:0030431 1 0.067
regulation of tube size GO:0035150 2 0.066
regulation of cell death GO:0010941 103 0.065
sensory perception of smell GO:0007608 2 0.065
calcium ion transport into cytosol GO:0060402 3 0.063
regulation of programmed cell death GO:0043067 101 0.063
erk1 and erk2 cascade GO:0070371 4 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.061
response to ketone GO:1901654 1 0.061
response to nitrogen compound GO:1901698 19 0.061
Mouse
neurological system process GO:0050877 62 0.059
negative regulation of cellular metabolic process GO:0031324 77 0.059
cellular metal ion homeostasis GO:0006875 16 0.059
regulation of establishment of protein localization GO:0070201 4 0.059
regulation of heart contraction GO:0008016 32 0.058
ovulation cycle GO:0042698 2 0.058
regulation of circadian rhythm GO:0042752 4 0.058
response to organic cyclic compound GO:0014070 51 0.057
stem cell proliferation GO:0072089 4 0.057
regulation of nucleic acid templated transcription GO:1903506 213 0.057
renal system process GO:0003014 14 0.057
regulation of locomotion GO:0040012 55 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.056
larval development GO:0002164 2 0.056
cell surface receptor signaling pathway GO:0007166 325 0.055
regulation of phosphate metabolic process GO:0019220 43 0.055
positive regulation of cell communication GO:0010647 56 0.055
positive regulation of response to stimulus GO:0048584 80 0.055
regulation of oligodendrocyte differentiation GO:0048713 1 0.055
cytosolic calcium ion transport GO:0060401 3 0.055
response to nicotine GO:0035094 2 0.055
regulation of cyclase activity GO:0031279 12 0.054
cell cell signaling GO:0007267 52 0.053
Zebrafish Mouse
developmental growth GO:0048589 166 0.053
neuron differentiation GO:0030182 353 0.053
regulation of gene expression GO:0010468 265 0.053
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.052
positive regulation of signal transduction GO:0009967 56 0.052
transport GO:0006810 220 0.052
Mouse
rna biosynthetic process GO:0032774 181 0.052
regulation of transmission of nerve impulse GO:0051969 1 0.051
oxidation reduction process GO:0055114 41 0.051
maintenance of location GO:0051235 4 0.051
death GO:0016265 121 0.050
regulation of phosphorus metabolic process GO:0051174 43 0.050
regulation of erk1 and erk2 cascade GO:0070372 4 0.050
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
intracellular estrogen receptor signaling pathway GO:0030520 3 0.048
blood circulation GO:0008015 87 0.048
regulation of cell communication GO:0010646 232 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.046
growth GO:0040007 174 0.046
negative regulation of hormone secretion GO:0046888 2 0.046
camera type eye development GO:0043010 222 0.045
negative regulation of phosphate metabolic process GO:0045936 13 0.044
head development GO:0060322 303 0.044
negative regulation of response to stimulus GO:0048585 104 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.044
positive regulation of cellular component biogenesis GO:0044089 3 0.043
cellular macromolecule biosynthetic process GO:0034645 224 0.043
behavior GO:0007610 74 0.043
long chain fatty acid transport GO:0015909 1 0.043
steroid hormone mediated signaling pathway GO:0043401 9 0.042
muscle system process GO:0003012 20 0.042
cell proliferation GO:0008283 80 0.041
positive regulation of gene expression GO:0010628 71 0.041
monovalent inorganic cation homeostasis GO:0055067 9 0.040
positive regulation of stem cell proliferation GO:2000648 1 0.040
positive regulation of multicellular organismal process GO:0051240 52 0.040
Human Mouse Rat
cellular localization GO:0051641 97 0.040
Mouse
neuron development GO:0048666 262 0.040
single organism behavior GO:0044708 24 0.040
Rat
positive regulation of secretion by cell GO:1903532 1 0.039
neuron projection development GO:0031175 180 0.039
positive regulation of cell cycle GO:0045787 3 0.039
apoptotic process GO:0006915 116 0.039
multicellular organismal response to stress GO:0033555 2 0.039
negative regulation of biosynthetic process GO:0009890 55 0.038
positive regulation of secretion GO:0051047 1 0.038
cellular ion homeostasis GO:0006873 17 0.036
sensory perception of pain GO:0019233 1 0.036
circulatory system process GO:0003013 87 0.036
ovulation cycle process GO:0022602 2 0.035
negative regulation of apoptotic process GO:0043066 55 0.035
regulation of rna biosynthetic process GO:2001141 213 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
transmission of nerve impulse GO:0019226 19 0.035
regulation of membrane potential GO:0042391 23 0.035
positive regulation of rna metabolic process GO:0051254 59 0.033
regulation of transport GO:0051049 45 0.033
gland development GO:0048732 143 0.033
Zebrafish
response to dexamethasone GO:0071548 1 0.033
axon development GO:0061564 166 0.033
regulation of reproductive process GO:2000241 4 0.033
positive regulation of blood circulation GO:1903524 2 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
response to amphetamine GO:0001975 1 0.032
positive regulation of rna biosynthetic process GO:1902680 57 0.032
developmental growth involved in morphogenesis GO:0060560 86 0.031
metal ion transport GO:0030001 58 0.031
axonogenesis GO:0007409 152 0.031
skeletal system development GO:0001501 181 0.030
regulation of apoptotic process GO:0042981 98 0.030
regulation of lyase activity GO:0051339 12 0.030
inner ear development GO:0048839 126 0.030
female gonad development GO:0008585 4 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
cellular response to light stimulus GO:0071482 4 0.029
transmembrane transport GO:0055085 120 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
negative regulation of signaling GO:0023057 96 0.028
multicellular organismal signaling GO:0035637 22 0.027
phototransduction GO:0007602 2 0.027
sensory perception GO:0007600 39 0.027
development of primary female sexual characteristics GO:0046545 4 0.026
smooth muscle contraction GO:0006939 2 0.026
rhythmic process GO:0048511 21 0.026
cellular divalent inorganic cation homeostasis GO:0072503 13 0.026
hormone secretion GO:0046879 2 0.026
Mouse
cellular ketone metabolic process GO:0042180 11 0.025
negative regulation of cell communication GO:0010648 96 0.025
regulation of transporter activity GO:0032409 2 0.025
cellular chemical homeostasis GO:0055082 17 0.025
axon extension GO:0048675 45 0.024
negative regulation of protein kinase b signaling GO:0051898 2 0.024
nucleic acid templated transcription GO:0097659 181 0.024
regulation of rna metabolic process GO:0051252 224 0.024
divalent metal ion transport GO:0070838 20 0.024
brain development GO:0007420 293 0.024
regulation of cell development GO:0060284 100 0.024
regulation of protein transport GO:0051223 3 0.024
regulation of growth GO:0040008 42 0.023
organelle organization GO:0006996 227 0.023
phagocytosis GO:0006909 3 0.023
hormone transport GO:0009914 2 0.023
Mouse
cation transport GO:0006812 81 0.022
chemotaxis GO:0006935 104 0.022
regulation of transmembrane transport GO:0034762 18 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.022
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.022
feeding behavior GO:0007631 5 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
positive regulation of catabolic process GO:0009896 4 0.021
response to corticosteroid GO:0031960 1 0.021
heart contraction GO:0060047 71 0.021
peptide transport GO:0015833 1 0.021
Mouse
response to organic substance GO:0010033 153 0.021
Mouse
optomotor response GO:0071632 1 0.021
cellular cation homeostasis GO:0030003 17 0.020
protein secretion GO:0009306 1 0.020
organic substance transport GO:0071702 58 0.020
Mouse
negative regulation of secretion GO:0051048 2 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
axon guidance GO:0007411 86 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
response to lipid GO:0033993 60 0.020
neuromuscular synaptic transmission GO:0007274 2 0.020
ion transmembrane transport GO:0034220 91 0.020
multicellular organism reproduction GO:0032504 35 0.019
rhodopsin mediated signaling pathway GO:0016056 1 0.019
negative regulation of epithelial cell proliferation GO:0050680 1 0.019
cellular homeostasis GO:0019725 26 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
regulation of catalytic activity GO:0050790 55 0.019
taxis GO:0042330 109 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
neuron projection extension GO:1990138 45 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
response to stress GO:0006950 263 0.018
ameboidal type cell migration GO:0001667 143 0.018
monoamine transport GO:0015844 1 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
negative regulation of cyclase activity GO:0031280 6 0.018
circadian behavior GO:0048512 5 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
ventral spinal cord development GO:0021517 35 0.018
catechol containing compound metabolic process GO:0009712 2 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
fatty acid transport GO:0015908 1 0.017
circadian regulation of gene expression GO:0032922 8 0.017
regulation of cellular ph GO:0030641 1 0.017
negative regulation of secretion by cell GO:1903531 2 0.017
exocytosis GO:0006887 1 0.017
positive regulation of inflammatory response GO:0050729 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
negative regulation of catalytic activity GO:0043086 21 0.017
positive regulation of cell death GO:0010942 29 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of cell division GO:0051781 2 0.017
macromolecule modification GO:0043412 111 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
positive regulation of metabolic process GO:0009893 108 0.016
cardiac cell fate commitment GO:0060911 1 0.016
regulation of cell growth GO:0001558 29 0.016
establishment of localization in cell GO:0051649 77 0.016
Mouse
specification of symmetry GO:0009799 204 0.016
cartilage development GO:0051216 96 0.015
regulation of protein complex assembly GO:0043254 3 0.015
muscle structure development GO:0061061 196 0.015
fertilization GO:0009566 3 0.015
regulation of intracellular ph GO:0051453 1 0.015
response to nutrient levels GO:0031667 10 0.015
Rat
response to wounding GO:0009611 116 0.015
limbic system development GO:0021761 16 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
myofibril assembly GO:0030239 48 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
regulation of neurogenesis GO:0050767 87 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of fatty acid metabolic process GO:0019217 1 0.015
glucose homeostasis GO:0042593 1 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
gall bladder development GO:0061010 1 0.015
response to radiation GO:0009314 51 0.015
actin filament based process GO:0030029 64 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
developmental cell growth GO:0048588 52 0.014
response to hormone GO:0009725 48 0.014
Mouse
cellular amine metabolic process GO:0044106 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of calcium ion transport GO:0051924 2 0.014
regulation of nervous system development GO:0051960 90 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
microtubule polymerization GO:0046785 2 0.014
regulation of developmental growth GO:0048638 38 0.014
mechanosensory behavior GO:0007638 2 0.013
dopamine metabolic process GO:0042417 2 0.013
anterior head development GO:0097065 2 0.013
multi organism process GO:0051704 134 0.013
regulation of homeostatic process GO:0032844 9 0.013
Human Mouse
multi organism reproductive process GO:0044703 36 0.013
intestinal absorption GO:0050892 2 0.013
specification of organ identity GO:0010092 2 0.013
rhythmic behavior GO:0007622 5 0.013
negative regulation of lyase activity GO:0051350 6 0.013
kupffer s vesicle development GO:0070121 50 0.012
oxoacid metabolic process GO:0043436 31 0.012
cellular response to external stimulus GO:0071496 2 0.012
forebrain development GO:0030900 96 0.012
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.012
regulation of cell morphogenesis GO:0022604 42 0.012
cell migration in hindbrain GO:0021535 7 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
neurotransmitter secretion GO:0007269 2 0.012
catecholamine metabolic process GO:0006584 2 0.012
response to alcohol GO:0097305 14 0.012
mapk cascade GO:0000165 18 0.012
cellular response to organic substance GO:0071310 105 0.012
response to steroid hormone GO:0048545 35 0.012
regulation of hormone secretion GO:0046883 2 0.012
generation of precursor metabolites and energy GO:0006091 5 0.012
regulation of cellular localization GO:0060341 12 0.012
positive regulation of phospholipase c activity GO:0010863 1 0.012
positive regulation of developmental process GO:0051094 50 0.012
hepatocyte proliferation GO:0072574 2 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
cellular hormone metabolic process GO:0034754 19 0.012
protein polymerization GO:0051258 4 0.012
response to amine GO:0014075 1 0.012
regulation of molecular function GO:0065009 70 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
cytokinesis GO:0000910 3 0.011
mitochondrion organization GO:0007005 4 0.011
ph reduction GO:0045851 1 0.011
regulation of ion homeostasis GO:2000021 7 0.011
regulation of cellular component movement GO:0051270 55 0.011
regulation of anatomical structure size GO:0090066 33 0.011
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.011
glutamate receptor signaling pathway GO:0007215 1 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
phenol containing compound biosynthetic process GO:0046189 4 0.011
negative regulation of gene expression GO:0010629 65 0.011
segmentation GO:0035282 97 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
Rat
positive regulation of cellular catabolic process GO:0031331 3 0.011
cation transmembrane transport GO:0098655 65 0.011
calcium ion transport GO:0006816 18 0.011
cellular protein modification process GO:0006464 100 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
regulation of lipid catabolic process GO:0050994 2 0.011
cell fate commitment GO:0045165 99 0.010
compound eye development GO:0048749 2 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
response to metal ion GO:0010038 34 0.010
regulation of cell motility GO:2000145 46 0.010
protein metabolic process GO:0019538 183 0.010
cell adhesion mediated by integrin GO:0033627 1 0.010

mc4r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of metabolism DOID:0014667 0 0.020
Human
osteochondrodysplasia DOID:2256 0 0.012
bone development disease DOID:0080006 0 0.012
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012