Danio rerio

0 known processes

prpf40a

PRP40 pre-mRNA processing factor 40 homolog A (yeast)

(Aliases: fnbp3,fb18h07,wu:fb18h07,wu:fe47a12,fe47a12)

prpf40a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based process GO:0007017 60 0.397
heterocycle biosynthetic process GO:0018130 215 0.314
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.270
regulation of metabolic process GO:0019222 359 0.269
aging GO:0007568 2 0.259
meiotic nuclear division GO:0007126 4 0.244
larval development GO:0002164 2 0.238
Worm
modification dependent protein catabolic process GO:0019941 3 0.222
gene expression GO:0010467 252 0.213
response to stress GO:0006950 263 0.213
rna biosynthetic process GO:0032774 181 0.195
nucleocytoplasmic transport GO:0006913 4 0.172
cellular protein catabolic process GO:0044257 4 0.170
cellular component movement GO:0006928 335 0.166
Human
organelle organization GO:0006996 227 0.163
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.155
positive regulation of cellular process GO:0048522 201 0.149
negative regulation of cellular process GO:0048523 283 0.133
organic substance biosynthetic process GO:1901576 289 0.132
single organism organelle organization GO:1902589 199 0.126
cellular nitrogen compound metabolic process GO:0034641 290 0.125
regulation of macromolecule metabolic process GO:0060255 317 0.124
regulation of biosynthetic process GO:0009889 250 0.123
organic cyclic compound metabolic process GO:1901360 301 0.118
ubiquitin dependent protein catabolic process GO:0006511 3 0.115
macromolecular complex subunit organization GO:0043933 74 0.112
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.106
regulation of protein transport GO:0051223 3 0.105
cell motility GO:0048870 244 0.103
Human
nucleic acid metabolic process GO:0090304 244 0.103
mitotic cell cycle GO:0000278 64 0.102
regulation of nitrogen compound metabolic process GO:0051171 251 0.102
regulation of rna biosynthetic process GO:2001141 213 0.097
regulation of cellular metabolic process GO:0031323 320 0.097
alternative mrna splicing via spliceosome GO:0000380 1 0.096
negative regulation of biological process GO:0048519 304 0.095
regulation of nucleic acid templated transcription GO:1903506 213 0.094
macromolecule biosynthetic process GO:0009059 227 0.093
cellular biosynthetic process GO:0044249 286 0.092
heterocycle metabolic process GO:0046483 290 0.091
regulation of primary metabolic process GO:0080090 311 0.090
cellular macromolecule metabolic process GO:0044260 391 0.090
positive regulation of biological process GO:0048518 253 0.089
Worm
regulation of rna metabolic process GO:0051252 224 0.089
aromatic compound biosynthetic process GO:0019438 217 0.088
rna metabolic process GO:0016070 219 0.087
proteasomal protein catabolic process GO:0010498 2 0.086
transcription dna templated GO:0006351 181 0.085
nucleobase containing compound biosynthetic process GO:0034654 205 0.085
regulation of developmental process GO:0050793 247 0.083
Human Worm
regulation of transcription dna templated GO:0006355 213 0.081
programmed cell death GO:0012501 119 0.080
protein import into nucleus GO:0006606 3 0.078
nucleobase containing compound metabolic process GO:0006139 274 0.076
negative regulation of synapse assembly GO:0051964 2 0.076
negative regulation of nuclear division GO:0051784 3 0.075
biosynthetic process GO:0009058 294 0.074
cellular macromolecule biosynthetic process GO:0034645 224 0.074
single organism localization GO:1902578 225 0.074
defense response GO:0006952 47 0.073
regulation of response to stimulus GO:0048583 269 0.073
nuclear pore organization GO:0006999 2 0.071
organelle assembly GO:0070925 110 0.070
regulation of meiotic cell cycle GO:0051445 1 0.070
locomotion GO:0040011 313 0.069
Human
protein localization to nucleus GO:0034504 3 0.069
regulation of nucleocytoplasmic transport GO:0046822 2 0.069
dorsal ventral pattern formation GO:0009953 125 0.068
regulation of intracellular protein transport GO:0033157 3 0.066
regulation of synapse organization GO:0050807 3 0.066
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.066
negative regulation of mitosis GO:0045839 3 0.065
pole plasm assembly GO:0007315 4 0.063
response to external stimulus GO:0009605 264 0.063
regulation of establishment of protein localization GO:0070201 4 0.063
response to chemical GO:0042221 320 0.062
regulation of multicellular organismal development GO:2000026 223 0.061
oocyte anterior posterior axis specification GO:0007314 4 0.060
maternal determination of anterior posterior axis embryo GO:0008358 4 0.059
nuclear import GO:0051170 3 0.058
regulation of mrna processing GO:0050684 3 0.058
stem cell maintenance GO:0019827 4 0.057
signal transduction GO:0007165 455 0.057
protein metabolic process GO:0019538 183 0.056
response to biotic stimulus GO:0009607 97 0.056
regulation of synapse assembly GO:0051963 3 0.056
oocyte differentiation GO:0009994 14 0.056
maintenance of location GO:0051235 4 0.055
single organism nuclear import GO:1902593 3 0.055
establishment of protein localization to organelle GO:0072594 4 0.055
nuclear transport GO:0051169 4 0.053
synaptic growth at neuromuscular junction GO:0051124 2 0.052
lateral inhibition GO:0046331 1 0.052
protein targeting to nucleus GO:0044744 3 0.052
regulation of signaling GO:0023051 235 0.052
regulation of cellular protein catabolic process GO:1903362 1 0.052
generation of neurons GO:0048699 385 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.051
negative regulation of multicellular organismal process GO:0051241 69 0.051
regulation of biological quality GO:0065008 263 0.049
Human
positive regulation of transport GO:0051050 2 0.049
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
protein complex disassembly GO:0043241 1 0.046
protein acetylation GO:0006473 2 0.046
protein complex subunit organization GO:0071822 46 0.045
regulation of protein catabolic process GO:0042176 1 0.045
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.045
transcription from rna polymerase ii promoter GO:0006366 80 0.044
cell death GO:0008219 121 0.044
cellular component assembly GO:0022607 170 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
immune system process GO:0002376 241 0.043
establishment of localization GO:0051234 244 0.043
Worm
microtubule cytoskeleton organization GO:0000226 33 0.041
cellular localization GO:0051641 97 0.040
localization of cell GO:0051674 244 0.039
Human
regulation of protein localization to nucleus GO:1900180 2 0.039
intracellular mrna localization GO:0008298 1 0.039
multi organism process GO:0051704 134 0.038
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.038
chromatin modification GO:0016568 21 0.038
negative regulation of metabolic process GO:0009892 86 0.037
mitotic cell cycle process GO:1903047 48 0.037
internal protein amino acid acetylation GO:0006475 2 0.037
cellular component biogenesis GO:0044085 178 0.037
cellular macromolecular complex assembly GO:0034622 24 0.037
cellular component disassembly GO:0022411 1 0.036
regulation of cell cycle GO:0051726 52 0.036
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.036
nucleic acid templated transcription GO:0097659 181 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
cell cycle GO:0007049 93 0.036
Human
response to organic substance GO:0010033 153 0.035
macromolecule localization GO:0033036 54 0.035
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.034
response to abiotic stimulus GO:0009628 122 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.033
mitotic g2 dna damage checkpoint GO:0007095 3 0.033
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
regulation of protein complex assembly GO:0043254 3 0.033
positive regulation of catabolic process GO:0009896 4 0.033
cellular catabolic process GO:0044248 27 0.032
regulation of gene expression GO:0010468 265 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
regulation of localization GO:0032879 104 0.032
regulation of cell shape GO:0008360 1 0.032
Human
multicellular organism growth GO:0035264 4 0.032
Worm
apoptotic process GO:0006915 116 0.032
phagocytosis GO:0006909 3 0.032
response to uv GO:0009411 3 0.031
single organism metabolic process GO:0044710 217 0.031
oocyte axis specification GO:0007309 5 0.030
macromolecular complex assembly GO:0065003 35 0.030
cell projection morphogenesis GO:0048858 244 0.030
cytoskeleton organization GO:0007010 96 0.029
Human
macromolecular complex disassembly GO:0032984 1 0.029
organelle fission GO:0048285 23 0.029
cell migration GO:0016477 237 0.028
Human
regulation of translational initiation GO:0006446 1 0.028
positive regulation of metabolic process GO:0009893 108 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
transport GO:0006810 220 0.027
Worm
g2 dna damage checkpoint GO:0031572 3 0.027
protein import GO:0017038 3 0.026
regulation of protein targeting GO:1903533 2 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
regulation of cell division GO:0051302 12 0.025
Human
regionalization GO:0003002 274 0.025
regulation of cell differentiation GO:0045595 142 0.024
cell cycle process GO:0022402 53 0.024
Human
regulation of signal transduction GO:0009966 225 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
Worm
meiotic cell cycle process GO:1903046 3 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
multi organism cellular process GO:0044764 2 0.024
death GO:0016265 121 0.024
taxis GO:0042330 109 0.023
neuron development GO:0048666 262 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
response to drug GO:0042493 3 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.022
Worm
cell projection organization GO:0030030 284 0.022
regulation of cellular protein metabolic process GO:0032268 52 0.022
single organism transport GO:0044765 206 0.022
intracellular signal transduction GO:0035556 85 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
neuroblast proliferation GO:0007405 2 0.022
negative regulation of translation GO:0017148 1 0.022
protein acylation GO:0043543 3 0.022
negative regulation of ras protein signal transduction GO:0046580 1 0.022
oocyte construction GO:0007308 5 0.021
neuron differentiation GO:0030182 353 0.021
nuclear division GO:0000280 23 0.021
posttranscriptional regulation of gene expression GO:0010608 14 0.021
cell morphogenesis GO:0000902 289 0.021
Human
regulation of cell cycle process GO:0010564 20 0.021
Human
rna localization GO:0006403 4 0.021
regulation of gene expression epigenetic GO:0040029 11 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
developmental growth GO:0048589 166 0.020
Worm
xenobiotic metabolic process GO:0006805 4 0.020
cellular protein modification process GO:0006464 100 0.020
regulation of cell communication GO:0010646 232 0.020
rna processing GO:0006396 25 0.020
lipid storage GO:0019915 1 0.020
cellular protein metabolic process GO:0044267 129 0.020
meiosis i GO:0007127 1 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
Worm
regulation of mrna splicing via spliceosome GO:0048024 3 0.019
protein modification process GO:0036211 100 0.019
negative regulation of cell cycle process GO:0010948 9 0.019
autophagy GO:0006914 4 0.018
negative regulation of gene expression GO:0010629 65 0.018
regulation of cellular component organization GO:0051128 86 0.018
Human
viral process GO:0016032 1 0.018
single organism cellular localization GO:1902580 46 0.018
proteolysis GO:0006508 38 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
positive regulation of nucleic acid templated transcription GO:1903508 57 0.018
dsrna fragmentation GO:0031050 1 0.017
negative regulation of transcription dna templated GO:0045892 45 0.017
nuclear pore complex assembly GO:0051292 2 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of cell development GO:0060284 100 0.017
neuron projection development GO:0031175 180 0.017
positive regulation of gene expression GO:0010628 71 0.017
negative regulation of developmental process GO:0051093 65 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
cellular response to external stimulus GO:0071496 2 0.017
cellular macromolecule localization GO:0070727 21 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
Worm
cellular response to starvation GO:0009267 1 0.016
embryonic organ development GO:0048568 381 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
regulation of nervous system development GO:0051960 90 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
gamete generation GO:0007276 33 0.016
cell part morphogenesis GO:0032990 246 0.016
protein methylation GO:0006479 13 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
establishment of localization in cell GO:0051649 77 0.015
cell maturation GO:0048469 23 0.015
positive regulation of cell cycle GO:0045787 3 0.015
germ cell development GO:0007281 22 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
translational initiation GO:0006413 3 0.015
interspecies interaction between organisms GO:0044419 4 0.015
rna 3 end processing GO:0031123 2 0.015
multicellular organism reproduction GO:0032504 35 0.015
Worm
phosphorus metabolic process GO:0006793 109 0.015
amine metabolic process GO:0009308 2 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
macromolecule modification GO:0043412 111 0.015
centrosome cycle GO:0007098 1 0.015
blood circulation GO:0008015 87 0.015
reproduction GO:0000003 40 0.015
Worm
cell growth GO:0016049 57 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
macroautophagy GO:0016236 1 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
locomotor rhythm GO:0045475 3 0.014
adult behavior GO:0030534 2 0.014
cellular ketone metabolic process GO:0042180 11 0.014
organic substance transport GO:0071702 58 0.014
nucleobase containing compound transport GO:0015931 2 0.014
rna stabilization GO:0043489 4 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
protein stabilization GO:0050821 2 0.014
ras protein signal transduction GO:0007265 7 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.013
establishment of organelle localization GO:0051656 45 0.013
cell substrate junction assembly GO:0007044 2 0.013
mrna 3 end processing GO:0031124 2 0.013
cytoplasm organization GO:0007028 4 0.013
stem cell proliferation GO:0072089 4 0.013
neuronal stem cell maintenance GO:0097150 2 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
response to hydrogen peroxide GO:0042542 3 0.013
cytokinesis GO:0000910 3 0.013
Human
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
negative regulation of signaling GO:0023057 96 0.013
compound eye development GO:0048749 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
regulation of reproductive process GO:2000241 4 0.013
meiotic spindle organization GO:0000212 1 0.013
cellular macromolecule catabolic process GO:0044265 12 0.013
mrna metabolic process GO:0016071 20 0.013
organelle localization GO:0051640 49 0.013
microtubule organizing center organization GO:0031023 1 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
Worm
positive regulation of mrna metabolic process GO:1903313 2 0.013
negative regulation of cell communication GO:0010648 96 0.013
stem cell differentiation GO:0048863 117 0.012
cell aging GO:0007569 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
central nervous system development GO:0007417 387 0.012
centrosome organization GO:0051297 1 0.012
pore complex assembly GO:0046931 2 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
protein polymerization GO:0051258 4 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
translation GO:0006412 5 0.012
negative regulation of cell cycle GO:0045786 14 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
mitochondrion organization GO:0007005 4 0.012
mitotic nuclear division GO:0007067 18 0.012
regulation of growth GO:0040008 42 0.012
Worm
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
regulation of locomotion GO:0040012 55 0.012
chromosome organization GO:0051276 31 0.012
response to external biotic stimulus GO:0043207 97 0.012
response to other organism GO:0051707 97 0.011
protein depolymerization GO:0051261 1 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
positive regulation of mrna processing GO:0050685 1 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
dendrite guidance GO:0070983 0 0.011
histone modification GO:0016570 20 0.011
regulation of organelle assembly GO:1902115 4 0.011
negative regulation of multi organism process GO:0043901 3 0.011
ribonucleoprotein complex biogenesis GO:0022613 13 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
small molecule metabolic process GO:0044281 77 0.011
heart process GO:0003015 71 0.011
cellular amine metabolic process GO:0044106 2 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
mrna transport GO:0051028 2 0.011
positive regulation of glial cell differentiation GO:0045687 1 0.011
segmentation GO:0035282 97 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
regulation of proteolysis GO:0030162 24 0.011
synaptic vesicle transport GO:0048489 1 0.011
response to virus GO:0009615 21 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
synaptic vesicle localization GO:0097479 1 0.010
cell adhesion GO:0007155 40 0.010
axonogenesis GO:0007409 152 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
posttranscriptional gene silencing GO:0016441 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
regulation of programmed cell death GO:0043067 101 0.010
negative regulation of catabolic process GO:0009895 3 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
system process GO:0003008 185 0.010
circulatory system process GO:0003013 87 0.010
double strand break repair GO:0006302 3 0.010
growth GO:0040007 174 0.010
Worm
organonitrogen compound metabolic process GO:1901564 74 0.010
female gonad development GO:0008585 4 0.010
catabolic process GO:0009056 32 0.010
cell cell signaling GO:0007267 52 0.010

prpf40a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.036
central nervous system disease DOID:331 0 0.036
amyotrophic lateral sclerosis DOID:332 0 0.036
disease of anatomical entity DOID:7 0 0.036
neurodegenerative disease DOID:1289 0 0.036
nervous system disease DOID:863 0 0.036
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of metabolism DOID:0014667 0 0.011