Danio rerio

0 known processes

tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

(Aliases: zgc:64168,wu:fb68h07)

tomm40 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.422
mitochondrion organization GO:0007005 4 0.381
negative regulation of biological process GO:0048519 304 0.248
mitochondrial transport GO:0006839 2 0.198
locomotion GO:0040011 313 0.197
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.185
negative regulation of cellular metabolic process GO:0031324 77 0.182
negative regulation of cellular process GO:0048523 283 0.179
establishment of protein localization to organelle GO:0072594 4 0.175
transmembrane transport GO:0055085 120 0.169
modification dependent protein catabolic process GO:0019941 3 0.159
nucleobase containing compound metabolic process GO:0006139 274 0.155
cellular protein catabolic process GO:0044257 4 0.140
embryo development ending in birth or egg hatching GO:0009792 271 0.138
establishment of localization GO:0051234 244 0.136
regulation of gene expression GO:0010468 265 0.117
transport GO:0006810 220 0.113
regulation of multicellular organism growth GO:0040014 4 0.112
nucleic acid metabolic process GO:0090304 244 0.110
regulation of cellular metabolic process GO:0031323 320 0.110
organelle organization GO:0006996 227 0.107
protein import GO:0017038 3 0.102
cellular macromolecule metabolic process GO:0044260 391 0.095
protein metabolic process GO:0019538 183 0.093
aging GO:0007568 2 0.093
regulation of metabolic process GO:0019222 359 0.091
gene expression GO:0010467 252 0.085
signal transduction GO:0007165 455 0.083
response to stress GO:0006950 263 0.079
cellular respiration GO:0045333 3 0.079
aromatic compound biosynthetic process GO:0019438 217 0.078
cellular response to stress GO:0033554 62 0.078
negative regulation of protein phosphorylation GO:0001933 4 0.077
nitrogen compound metabolic process GO:0006807 319 0.074
rna metabolic process GO:0016070 219 0.073
cellular component assembly GO:0022607 170 0.072
regulation of primary metabolic process GO:0080090 311 0.066
regulation of macromolecule metabolic process GO:0060255 317 0.065
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.065
single organism localization GO:1902578 225 0.065
cellular nitrogen compound metabolic process GO:0034641 290 0.063
transcription from rna polymerase ii promoter GO:0006366 80 0.063
cell migration GO:0016477 237 0.061
cell motility GO:0048870 244 0.060
rna processing GO:0006396 25 0.060
oocyte maturation GO:0001556 4 0.060
cellular localization GO:0051641 97 0.060
multicellular organism growth GO:0035264 4 0.059
organic substance biosynthetic process GO:1901576 289 0.059
cellular protein metabolic process GO:0044267 129 0.059
single organism organelle organization GO:1902589 199 0.058
single organism transport GO:0044765 206 0.056
cellular component biogenesis GO:0044085 178 0.055
cell surface receptor signaling pathway GO:0007166 325 0.054
ubiquitin dependent protein catabolic process GO:0006511 3 0.053
multicellular organismal reproductive process GO:0048609 35 0.051
modification dependent macromolecule catabolic process GO:0043632 3 0.049
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.049
heterocycle biosynthetic process GO:0018130 215 0.048
cellular protein localization GO:0034613 20 0.047
organic cyclic compound metabolic process GO:1901360 301 0.047
cellular component movement GO:0006928 335 0.046
single organism cellular localization GO:1902580 46 0.046
positive regulation of cellular process GO:0048522 201 0.045
protein secretion GO:0009306 1 0.043
macromolecule localization GO:0033036 54 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.040
single fertilization GO:0007338 3 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
nucleic acid templated transcription GO:0097659 181 0.040
regulation of developmental process GO:0050793 247 0.039
heterocycle metabolic process GO:0046483 290 0.038
protein modification process GO:0036211 100 0.038
reproductive process GO:0022414 40 0.038
intracellular transport GO:0046907 32 0.037
translational initiation GO:0006413 3 0.037
protein localization GO:0008104 40 0.037
phagocytosis GO:0006909 3 0.037
cellular protein modification process GO:0006464 100 0.037
regulation of multicellular organismal process GO:0051239 277 0.036
positive regulation of biological process GO:0048518 253 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.035
cellular macromolecule biosynthetic process GO:0034645 224 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
negative regulation of metabolic process GO:0009892 86 0.032
regulation of protein ubiquitination GO:0031396 3 0.032
ovulation cycle process GO:0022602 2 0.032
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.031
cellular biosynthetic process GO:0044249 286 0.031
microtubule organizing center organization GO:0031023 1 0.031
single organism reproductive process GO:0044702 40 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
regulation of transcription dna templated GO:0006355 213 0.031
gamete generation GO:0007276 33 0.030
regulation of mrna processing GO:0050684 3 0.030
regulation of erk1 and erk2 cascade GO:0070372 4 0.030
protein complex subunit organization GO:0071822 46 0.030
regulation of signal transduction GO:0009966 225 0.030
protein complex biogenesis GO:0070271 30 0.030
multicellular organism reproduction GO:0032504 35 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
regulation of biosynthetic process GO:0009889 250 0.029
regulation of protein catabolic process GO:0042176 1 0.029
biosynthetic process GO:0009058 294 0.029
response to topologically incorrect protein GO:0035966 2 0.029
developmental growth GO:0048589 166 0.028
regulation of cell communication GO:0010646 232 0.027
regulation of protein complex assembly GO:0043254 3 0.027
cellular macromolecule localization GO:0070727 21 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
nuclear migration GO:0007097 3 0.027
regulation of response to stimulus GO:0048583 269 0.027
macromolecule modification GO:0043412 111 0.026
positive regulation of transport GO:0051050 2 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
protein polyubiquitination GO:0000209 4 0.025
regulation of signaling GO:0023051 235 0.025
mitotic g2 dna damage checkpoint GO:0007095 3 0.024
centrosome organization GO:0051297 1 0.024
cytoskeleton organization GO:0007010 96 0.024
spermatid development GO:0007286 2 0.024
vesicle mediated transport GO:0016192 22 0.024
reproduction GO:0000003 40 0.024
stem cell differentiation GO:0048863 117 0.024
negative regulation of cell death GO:0060548 60 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
negative regulation of signaling GO:0023057 96 0.023
negative regulation of cell communication GO:0010648 96 0.023
organic substance transport GO:0071702 58 0.023
pole plasm assembly GO:0007315 4 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
response to chemical GO:0042221 320 0.023
protein targeting to nucleus GO:0044744 3 0.022
germ cell development GO:0007281 22 0.022
immune system process GO:0002376 241 0.022
generation of neurons GO:0048699 385 0.022
proteolysis GO:0006508 38 0.022
regulation of cell cycle GO:0051726 52 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
developmental process involved in reproduction GO:0003006 27 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
negative regulation of signal transduction GO:0009968 94 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
regulation of proteolysis GO:0030162 24 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of binding GO:0051098 3 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
digestive tract development GO:0048565 265 0.021
cell cycle GO:0007049 93 0.021
regulation of dendrite development GO:0050773 3 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
stem cell maintenance GO:0019827 4 0.020
positive regulation of cell cycle GO:0045787 3 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
single organism metabolic process GO:0044710 217 0.020
oxoacid metabolic process GO:0043436 31 0.020
digestive system development GO:0055123 289 0.020
macromolecular complex assembly GO:0065003 35 0.020
rna biosynthetic process GO:0032774 181 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.019
protein k63 linked ubiquitination GO:0070534 2 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
cellular response to unfolded protein GO:0034620 2 0.019
programmed cell death GO:0012501 119 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
organelle transport along microtubule GO:0072384 1 0.019
positive regulation of catabolic process GO:0009896 4 0.019
spermatid differentiation GO:0048515 2 0.019
response to biotic stimulus GO:0009607 97 0.019
negative regulation of phosphate metabolic process GO:0045936 13 0.019
regulation of cell differentiation GO:0045595 142 0.018
establishment of localization in cell GO:0051649 77 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
regulation of cellular component organization GO:0051128 86 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of stem cell differentiation GO:2000736 4 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
alternative mrna splicing via spliceosome GO:0000380 1 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
meiotic nuclear division GO:0007126 4 0.017
mitotic g2 m transition checkpoint GO:0044818 3 0.017
negative regulation of gene expression GO:0010629 65 0.017
compound eye development GO:0048749 2 0.017
localization of cell GO:0051674 244 0.017
cell death GO:0008219 121 0.017
cell cycle process GO:0022402 53 0.017
regulation of muscle hypertrophy GO:0014743 2 0.016
single organism intracellular transport GO:1902582 25 0.016
germ line stem cell maintenance GO:0030718 2 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
microtubule based process GO:0007017 60 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
negative regulation of kinase activity GO:0033673 4 0.016
response to unfolded protein GO:0006986 2 0.016
ion transport GO:0006811 114 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
double strand break repair GO:0006302 3 0.016
regulation of biological quality GO:0065008 263 0.016
embryonic limb morphogenesis GO:0030326 2 0.016
response to uv GO:0009411 3 0.015
regulation of protein metabolic process GO:0051246 56 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
intracellular receptor signaling pathway GO:0030522 30 0.015
phosphorus metabolic process GO:0006793 109 0.015
immune system development GO:0002520 191 0.015
spindle assembly GO:0051225 2 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
tube morphogenesis GO:0035239 349 0.015
sexual reproduction GO:0019953 36 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
pronuclear migration GO:0035046 1 0.014
regulation of cell death GO:0010941 103 0.014
cellular component disassembly GO:0022411 1 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
apoptotic process GO:0006915 116 0.014
cellular response to nutrient levels GO:0031669 2 0.014
fertilization GO:0009566 3 0.014
transcription dna templated GO:0006351 181 0.014
regulation of rna metabolic process GO:0051252 224 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
negative regulation of mitosis GO:0045839 3 0.014
female sex differentiation GO:0046660 4 0.014
macromolecular complex disassembly GO:0032984 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
gtp metabolic process GO:0046039 4 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of mesoderm development GO:2000380 11 0.013
cellular amine metabolic process GO:0044106 2 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
golgi organization GO:0007030 1 0.013
neuron differentiation GO:0030182 353 0.013
ovulation cycle GO:0042698 2 0.013
cell projection organization GO:0030030 284 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
growth GO:0040007 174 0.013
protein complex assembly GO:0006461 30 0.013
regulation of synapse organization GO:0050807 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
mrna stabilization GO:0048255 4 0.012
sensory perception of pain GO:0019233 1 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
amine metabolic process GO:0009308 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
death GO:0016265 121 0.012
vasculature development GO:0001944 278 0.012
blood vessel development GO:0001568 246 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
cell substrate adhesion GO:0031589 4 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
stem cell proliferation GO:0072089 4 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.012
developmental programmed cell death GO:0010623 4 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
multi organism reproductive process GO:0044703 36 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
anion transport GO:0006820 38 0.012
lateral inhibition GO:0046331 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
organelle assembly GO:0070925 110 0.012
embryonic organ development GO:0048568 381 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
meiotic chromosome segregation GO:0045132 3 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
embryonic pattern specification GO:0009880 44 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
hemopoiesis GO:0030097 183 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
centrosome cycle GO:0007098 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of programmed cell death GO:0043067 101 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of calcium ion transport GO:0051924 2 0.011
positive regulation of gene expression GO:0010628 71 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
b cell activation GO:0042113 2 0.011
apoptotic process involved in development GO:1902742 2 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
mitotic cell cycle process GO:1903047 48 0.011
mesenchyme development GO:0060485 127 0.011
cellular response to external stimulus GO:0071496 2 0.011
localization within membrane GO:0051668 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.010
macromolecule methylation GO:0043414 19 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of protein transport GO:0051223 3 0.010
cell projection morphogenesis GO:0048858 244 0.010
multi organism process GO:0051704 134 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
rna splicing GO:0008380 16 0.010
er nucleus signaling pathway GO:0006984 2 0.010
gastrulation GO:0007369 208 0.010
somitogenesis GO:0001756 87 0.010

tomm40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
musculoskeletal system disease DOID:17 0 0.035
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
myopathy DOID:423 0 0.013