Danio rerio

0 known processes

tbx4

T-box 4

(Aliases: zf-tbx4,zTbx4)

tbx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retinal ganglion cell axon guidance GO:0031290 35 0.177
generation of neurons GO:0048699 385 0.132
synaptic target recognition GO:0008039 1 0.129
blood vessel morphogenesis GO:0048514 216 0.109
eye development GO:0001654 277 0.096
regulation of epithelial cell proliferation GO:0050678 3 0.084
head development GO:0060322 303 0.082
signal transduction GO:0007165 455 0.082
cellular macromolecule metabolic process GO:0044260 391 0.080
vasculature development GO:0001944 278 0.077
regulation of axon guidance GO:1902667 8 0.077
regulation of axonogenesis GO:0050770 32 0.075
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.071
skeletal system development GO:0001501 181 0.066
embryonic limb morphogenesis GO:0030326 2 0.059
central nervous system development GO:0007417 387 0.058
enzyme linked receptor protein signaling pathway GO:0007167 106 0.057
cellular component assembly involved in morphogenesis GO:0010927 107 0.054
adult behavior GO:0030534 2 0.053
skeletal system morphogenesis GO:0048705 102 0.053
regulation of rna biosynthetic process GO:2001141 213 0.051
regulation of response to stimulus GO:0048583 269 0.051
cell morphogenesis GO:0000902 289 0.050
skeletal muscle organ development GO:0060538 78 0.048
camera type eye development GO:0043010 222 0.047
embryonic organ morphogenesis GO:0048562 274 0.047
organic substance biosynthetic process GO:1901576 289 0.046
response to external stimulus GO:0009605 264 0.045
larval development GO:0002164 2 0.044
astrocyte differentiation GO:0048708 1 0.042
regulation of signal transduction GO:0009966 225 0.042
cell morphogenesis involved in differentiation GO:0000904 195 0.040
neuron development GO:0048666 262 0.039
regulation of cell differentiation GO:0045595 142 0.038
response to chemical GO:0042221 320 0.038
oxoacid metabolic process GO:0043436 31 0.038
nephron epithelium morphogenesis GO:0072088 1 0.037
mesenchymal cell differentiation GO:0048762 87 0.037
regulation of neuron projection development GO:0010975 40 0.037
regulation of extent of cell growth GO:0061387 29 0.036
regulation of heart contraction GO:0008016 32 0.036
ventral spinal cord development GO:0021517 35 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
embryonic skeletal system development GO:0048706 97 0.035
sensory organ morphogenesis GO:0090596 200 0.034
olfactory lobe development GO:0021988 4 0.034
neural precursor cell proliferation GO:0061351 20 0.034
maintenance of location GO:0051235 4 0.033
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.033
developmental programmed cell death GO:0010623 4 0.032
cell projection organization GO:0030030 284 0.032
regulation of signaling GO:0023051 235 0.032
inner ear morphogenesis GO:0042472 63 0.032
axon guidance GO:0007411 86 0.032
small molecule metabolic process GO:0044281 77 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
cell projection morphogenesis GO:0048858 244 0.031
neuron differentiation GO:0030182 353 0.031
regulation of developmental process GO:0050793 247 0.031
apoptotic process involved in morphogenesis GO:0060561 2 0.030
aging GO:0007568 2 0.029
cellular component assembly GO:0022607 170 0.029
regulation of transcription involved in cell fate commitment GO:0060850 1 0.028
organic acid metabolic process GO:0006082 31 0.028
embryonic camera type eye formation GO:0060900 10 0.028
axon development GO:0061564 166 0.027
central nervous system neuron differentiation GO:0021953 74 0.027
response to stress GO:0006950 263 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
cell growth GO:0016049 57 0.026
stem cell proliferation GO:0072089 4 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
negative regulation of nervous system development GO:0051961 22 0.026
connective tissue development GO:0061448 99 0.025
regulation of cell fate specification GO:0042659 20 0.025
sensory organ development GO:0007423 393 0.025
heterocycle metabolic process GO:0046483 290 0.025
peripheral nervous system development GO:0007422 55 0.024
angiogenesis GO:0001525 158 0.024
catecholamine biosynthetic process GO:0042423 2 0.024
multicellular organism growth GO:0035264 4 0.024
olfactory bulb development GO:0021772 4 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of cell communication GO:0010646 232 0.023
chordate embryonic development GO:0043009 271 0.023
ectodermal placode development GO:0071696 37 0.023
protein import GO:0017038 3 0.023
regulation of neuron migration GO:2001222 2 0.023
appendage development GO:0048736 80 0.023
brain development GO:0007420 293 0.023
gene expression GO:0010467 252 0.022
regulation of reproductive process GO:2000241 4 0.022
nephron tubule morphogenesis GO:0072078 1 0.022
amine metabolic process GO:0009308 2 0.022
locomotory behavior GO:0007626 34 0.022
mesenchyme development GO:0060485 127 0.022
bmp signaling pathway GO:0030509 52 0.022
response to external biotic stimulus GO:0043207 97 0.022
response to endogenous stimulus GO:0009719 83 0.022
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 5 0.022
regulation of cell fate commitment GO:0010453 22 0.022
retina development in camera type eye GO:0060041 146 0.022
circulatory system process GO:0003013 87 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.021
cellular component movement GO:0006928 335 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
developmental cell growth GO:0048588 52 0.021
appendage morphogenesis GO:0035107 56 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
system process GO:0003008 185 0.021
spinal cord development GO:0021510 46 0.021
regulation of axon extension GO:0030516 24 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
female sex differentiation GO:0046660 4 0.020
stem cell differentiation GO:0048863 117 0.020
nephron morphogenesis GO:0072028 2 0.020
chemotaxis GO:0006935 104 0.019
regulation of cell projection organization GO:0031344 44 0.019
neuron projection guidance GO:0097485 86 0.019
spinal cord motor neuron differentiation GO:0021522 26 0.019
embryonic skeletal joint development GO:0072498 3 0.019
growth GO:0040007 174 0.018
histone h3 k4 methylation GO:0051568 2 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.018
axonogenesis GO:0007409 152 0.018
dopamine metabolic process GO:0042417 2 0.018
neuron projection development GO:0031175 180 0.018
apoptotic process involved in development GO:1902742 2 0.018
protein homooligomerization GO:0051260 3 0.018
cell part morphogenesis GO:0032990 246 0.018
regulation of blood vessel size GO:0050880 2 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
regulation of neuron differentiation GO:0045664 56 0.017
distal tubule development GO:0072017 1 0.017
single organism metabolic process GO:0044710 217 0.017
regulation of blood circulation GO:1903522 32 0.017
cell proliferation in hindbrain GO:0021534 4 0.017
regulation of cell development GO:0060284 100 0.016
transmission of nerve impulse GO:0019226 19 0.016
embryonic camera type eye development GO:0031076 29 0.016
biosynthetic process GO:0009058 294 0.016
heart contraction GO:0060047 71 0.016
cell motility GO:0048870 244 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
embryonic organ development GO:0048568 381 0.016
sleep GO:0030431 1 0.016
striated muscle cell development GO:0055002 108 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
phenol containing compound biosynthetic process GO:0046189 4 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
regulation of anatomical structure size GO:0090066 33 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
mesenchymal cell development GO:0014031 78 0.015
cytokinesis GO:0000910 3 0.015
keratinocyte differentiation GO:0030216 0 0.015
cartilage development GO:0051216 96 0.015
regulation of circadian rhythm GO:0042752 4 0.015
nuclear import GO:0051170 3 0.015
regulation of mesoderm development GO:2000380 11 0.015
catechol containing compound biosynthetic process GO:0009713 2 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
midbrain development GO:0030901 28 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
renal tubule morphogenesis GO:0061333 1 0.014
organelle organization GO:0006996 227 0.014
regionalization GO:0003002 274 0.014
glial cell migration GO:0008347 3 0.014
regulation of protein transport GO:0051223 3 0.014
gabaergic neuron differentiation GO:0097154 2 0.014
embryonic camera type eye morphogenesis GO:0048596 19 0.014
homeostatic process GO:0042592 142 0.014
neural crest cell differentiation GO:0014033 72 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
lipid storage GO:0019915 1 0.014
visual behavior GO:0007632 10 0.014
regulation of nervous system development GO:0051960 90 0.014
regulation of protein complex assembly GO:0043254 3 0.014
convergent extension GO:0060026 118 0.014
endodermal cell fate determination GO:0007493 2 0.013
regulation of heart growth GO:0060420 2 0.013
cardiac cell fate commitment GO:0060911 1 0.013
locomotion GO:0040011 313 0.013
negative regulation of cell development GO:0010721 26 0.013
organelle assembly GO:0070925 110 0.013
multi organism process GO:0051704 134 0.013
positive regulation of transport GO:0051050 2 0.013
stem cell development GO:0048864 82 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
negative regulation of signaling GO:0023057 96 0.013
adrenergic receptor signaling pathway GO:0071875 5 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
negative regulation of secretion GO:0051048 2 0.013
hormone secretion GO:0046879 2 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
oocyte maturation GO:0001556 4 0.012
organonitrogen compound biosynthetic process GO:1901566 47 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
heart process GO:0003015 71 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
neuronal action potential GO:0019228 18 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of bmp signaling pathway GO:0030510 39 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
fin regeneration GO:0031101 51 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of cell size GO:0008361 29 0.012
myofibril assembly GO:0030239 48 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
cell fate specification GO:0001708 68 0.011
single organism nuclear import GO:1902593 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
negative regulation of axon extension GO:0030517 7 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
positive regulation of signaling GO:0023056 56 0.011
regulation of organ growth GO:0046620 3 0.011
optokinetic behavior GO:0007634 9 0.011
blood vessel development GO:0001568 246 0.011
protein import into nucleus GO:0006606 3 0.011
branching morphogenesis of a nerve GO:0048755 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
response to glucose GO:0009749 3 0.011
muscle cell differentiation GO:0042692 139 0.011
forebrain development GO:0030900 96 0.011
transcription dna templated GO:0006351 181 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
transport GO:0006810 220 0.011
nuclear transport GO:0051169 4 0.011
blood circulation GO:0008015 87 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
neurological system process GO:0050877 62 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
peripheral nervous system neuron axonogenesis GO:0048936 13 0.011
phagocytosis GO:0006909 3 0.010
muscle structure development GO:0061061 196 0.010
regulation of tube size GO:0035150 2 0.010
negative regulation of gastrulation GO:2000542 11 0.010
forebrain cell migration GO:0021885 1 0.010
central nervous system neuron development GO:0021954 29 0.010
nephron development GO:0072006 31 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
regulation of intracellular protein transport GO:0033157 3 0.010

tbx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.014
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
bone development disease DOID:0080006 0 0.013
cancer DOID:162 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011