Danio rerio

0 known processes

apaf1

apoptotic protease activating factor 1

(Aliases: MGC92565,zgc:136543,MGC136543)

apaf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.327
response to stress GO:0006950 263 0.244
cellular nitrogen compound biosynthetic process GO:0044271 218 0.133
signal transduction GO:0007165 455 0.130
negative regulation of cellular process GO:0048523 283 0.129
establishment of localization GO:0051234 244 0.120
neuron projection morphogenesis GO:0048812 161 0.113
cellular aromatic compound metabolic process GO:0006725 295 0.110
regulation of synapse organization GO:0050807 3 0.110
positive regulation of transport GO:0051050 2 0.107
glucose import GO:0046323 2 0.105
response to chemical GO:0042221 320 0.102
nuclear transport GO:0051169 4 0.099
aging GO:0007568 2 0.098
positive regulation of cellular component biogenesis GO:0044089 3 0.095
cellular macromolecule metabolic process GO:0044260 391 0.093
Human
nitrogen compound metabolic process GO:0006807 319 0.093
cognition GO:0050890 1 0.093
cell projection morphogenesis GO:0048858 244 0.091
response to external stimulus GO:0009605 264 0.088
transport GO:0006810 220 0.083
single organism localization GO:1902578 225 0.081
nucleocytoplasmic transport GO:0006913 4 0.081
cellular component movement GO:0006928 335 0.080
single organism transport GO:0044765 206 0.080
autophagy GO:0006914 4 0.079
regulation of establishment of protein localization GO:0070201 4 0.078
cell projection organization GO:0030030 284 0.075
regulation of cellular metabolic process GO:0031323 320 0.074
Human
regulation of multicellular organismal development GO:2000026 223 0.073
ubiquitin dependent protein catabolic process GO:0006511 3 0.073
heterocycle metabolic process GO:0046483 290 0.071
cell morphogenesis GO:0000902 289 0.069
cellular component morphogenesis GO:0032989 336 0.069
nucleic acid templated transcription GO:0097659 181 0.068
phagocytosis GO:0006909 3 0.067
neuron differentiation GO:0030182 353 0.067
regulation of cell differentiation GO:0045595 142 0.065
positive regulation of cell killing GO:0031343 2 0.065
central nervous system development GO:0007417 387 0.064
aromatic compound biosynthetic process GO:0019438 217 0.064
protein localization to nucleus GO:0034504 3 0.063
synaptic growth at neuromuscular junction GO:0051124 2 0.063
developmental growth GO:0048589 166 0.062
regulation of response to stimulus GO:0048583 269 0.061
cellular protein catabolic process GO:0044257 4 0.061
multicellular organism growth GO:0035264 4 0.060
cell part morphogenesis GO:0032990 246 0.060
response to organic substance GO:0010033 153 0.060
negative regulation of cell communication GO:0010648 96 0.059
regulation of multicellular organismal process GO:0051239 277 0.059
brain development GO:0007420 293 0.059
nucleic acid metabolic process GO:0090304 244 0.058
regulation of localization GO:0032879 104 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.058
cell surface receptor signaling pathway GO:0007166 325 0.057
regulation of protein transport GO:0051223 3 0.057
regulation of protein localization to nucleus GO:1900180 2 0.056
protein metabolic process GO:0019538 183 0.056
Human
post embryonic organ development GO:0048569 4 0.055
modification dependent protein catabolic process GO:0019941 3 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.054
nucleobase containing compound metabolic process GO:0006139 274 0.054
maintenance of location GO:0051235 4 0.053
morphogenesis of an epithelium GO:0002009 333 0.053
regulation of protein complex assembly GO:0043254 3 0.053
regulation of stem cell differentiation GO:2000736 4 0.052
regulation of signaling GO:0023051 235 0.052
regulation of synapse assembly GO:0051963 3 0.051
embryo development ending in birth or egg hatching GO:0009792 271 0.051
regulation of metabolic process GO:0019222 359 0.051
Human
organonitrogen compound metabolic process GO:1901564 74 0.051
chordate embryonic development GO:0043009 271 0.050
organelle organization GO:0006996 227 0.050
positive regulation of cell cycle GO:0045787 3 0.049
single organism metabolic process GO:0044710 217 0.049
negative regulation of biological process GO:0048519 304 0.049
rna metabolic process GO:0016070 219 0.049
biosynthetic process GO:0009058 294 0.049
regulation of protein targeting GO:1903533 2 0.049
anterior posterior pattern specification GO:0009952 152 0.048
regulation of signal transduction GO:0009966 225 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.047
microtubule organizing center organization GO:0031023 1 0.047
heterocycle biosynthetic process GO:0018130 215 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
extrinsic apoptotic signaling pathway GO:0097191 3 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.046
organic cyclic compound biosynthetic process GO:1901362 223 0.046
cellular biosynthetic process GO:0044249 286 0.046
intracellular signal transduction GO:0035556 85 0.045
regionalization GO:0003002 274 0.045
positive regulation of macromolecule metabolic process GO:0010604 93 0.045
Human
regulation of intracellular protein transport GO:0033157 3 0.045
small molecule metabolic process GO:0044281 77 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.045
cellular carbohydrate metabolic process GO:0044262 4 0.045
positive regulation of catabolic process GO:0009896 4 0.045
regulation of rna metabolic process GO:0051252 224 0.044
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.044
generation of neurons GO:0048699 385 0.044
cellular component biogenesis GO:0044085 178 0.043
modification dependent macromolecule catabolic process GO:0043632 3 0.043
adherens junction organization GO:0034332 4 0.043
negative regulation of synapse assembly GO:0051964 2 0.043
gtp metabolic process GO:0046039 4 0.043
positive regulation of biological process GO:0048518 253 0.042
Human
protein import GO:0017038 3 0.042
negative regulation of signaling GO:0023057 96 0.042
regulation of nucleocytoplasmic transport GO:0046822 2 0.042
gtp catabolic process GO:0006184 2 0.042
positive regulation of protein complex assembly GO:0031334 2 0.042
cellular response to radiation GO:0071478 4 0.041
regulation of developmental process GO:0050793 247 0.041
centrosome organization GO:0051297 1 0.041
guanosine containing compound catabolic process GO:1901069 2 0.041
regulation of protein import into nucleus GO:0042306 2 0.041
guanosine containing compound metabolic process GO:1901068 4 0.040
establishment of protein localization to organelle GO:0072594 4 0.040
transcription dna templated GO:0006351 181 0.040
cellular response to external stimulus GO:0071496 2 0.040
immune system process GO:0002376 241 0.040
regulation of cell communication GO:0010646 232 0.040
convergent extension GO:0060026 118 0.040
regulation of rna biosynthetic process GO:2001141 213 0.040
digestive system development GO:0055123 289 0.039
regulation of circadian rhythm GO:0042752 4 0.039
organic substance biosynthetic process GO:1901576 289 0.039
negative regulation of cytoplasmic transport GO:1903650 2 0.039
nucleobase containing compound biosynthetic process GO:0034654 205 0.039
protein targeting to nucleus GO:0044744 3 0.039
meiotic nuclear division GO:0007126 4 0.038
ameboidal type cell migration GO:0001667 143 0.038
neuron projection development GO:0031175 180 0.038
negative regulation of catabolic process GO:0009895 3 0.038
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
system process GO:0003008 185 0.037
female sex differentiation GO:0046660 4 0.037
cellular response to stress GO:0033554 62 0.037
cytokinesis GO:0000910 3 0.037
gene expression GO:0010467 252 0.037
Human
positive regulation of cellular process GO:0048522 201 0.037
Human
regulation of multicellular organism growth GO:0040014 4 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.036
stem cell maintenance GO:0019827 4 0.036
phosphate containing compound metabolic process GO:0006796 108 0.036
rna biosynthetic process GO:0032774 181 0.036
cellular response to organic substance GO:0071310 105 0.036
immune system development GO:0002520 191 0.036
regulation of organ growth GO:0046620 3 0.035
head development GO:0060322 303 0.035
heart development GO:0007507 313 0.035
actin polymerization or depolymerization GO:0008154 2 0.035
locomotion GO:0040011 313 0.035
organic substance transport GO:0071702 58 0.035
negative regulation of ras protein signal transduction GO:0046580 1 0.035
regulation of protein catabolic process GO:0042176 1 0.034
regulation of glucose import GO:0046324 1 0.034
tube morphogenesis GO:0035239 349 0.033
negative regulation of protein transport GO:0051224 3 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
regulation of cell projection assembly GO:0060491 4 0.033
cellular amine metabolic process GO:0044106 2 0.033
cellular response to starvation GO:0009267 1 0.033
centrosome cycle GO:0007098 1 0.033
regulation of cell development GO:0060284 100 0.033
growth GO:0040007 174 0.033
positive regulation of jun kinase activity GO:0043507 2 0.033
cell morphogenesis involved in differentiation GO:0000904 195 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
Human
positive regulation of jnk cascade GO:0046330 3 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
positive regulation of stress activated mapk cascade GO:0032874 3 0.031
rna localization GO:0006403 4 0.031
embryonic organ morphogenesis GO:0048562 274 0.031
regulation of biological quality GO:0065008 263 0.031
sleep GO:0030431 1 0.031
adult behavior GO:0030534 2 0.031
macromolecule modification GO:0043412 111 0.031
organelle assembly GO:0070925 110 0.031
mitochondrion organization GO:0007005 4 0.031
glucose homeostasis GO:0042593 1 0.031
cellular response to chemical stimulus GO:0070887 157 0.030
protein modification process GO:0036211 100 0.030
proteasomal protein catabolic process GO:0010498 2 0.030
apoptotic process GO:0006915 116 0.030
Human
response to glucose GO:0009749 3 0.030
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.030
cellular protein modification process GO:0006464 100 0.030
regulation of transcription dna templated GO:0006355 213 0.030
regulation of glucose transport GO:0010827 1 0.029
amine metabolic process GO:0009308 2 0.029
intracellular mrna localization GO:0008298 1 0.029
regulation of cell killing GO:0031341 2 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
cellular protein metabolic process GO:0044267 129 0.029
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.029
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
actin cytoskeleton organization GO:0030036 63 0.029
cell death GO:0008219 121 0.029
Human
neuron projection guidance GO:0097485 86 0.029
regulation of biosynthetic process GO:0009889 250 0.029
regulation of dendrite development GO:0050773 3 0.029
neuron development GO:0048666 262 0.029
determination of bilateral symmetry GO:0009855 204 0.029
cellular response to extracellular stimulus GO:0031668 2 0.028
phagocytosis engulfment GO:0006911 1 0.028
lipid storage GO:0019915 1 0.028
membrane invagination GO:0010324 1 0.028
regulation of peptidase activity GO:0052547 23 0.028
Human
phosphorylation GO:0016310 69 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.028
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.028
positive regulation of map kinase activity GO:0043406 3 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
segmentation GO:0035282 97 0.027
cellular response to nutrient levels GO:0031669 2 0.027
negative regulation of intracellular transport GO:0032387 3 0.027
response to wounding GO:0009611 116 0.027
cellular component assembly GO:0022607 170 0.027
cytoskeleton organization GO:0007010 96 0.027
localization of cell GO:0051674 244 0.027
cell migration GO:0016477 237 0.027
single organism nuclear import GO:1902593 3 0.027
negative regulation of multicellular organismal process GO:0051241 69 0.027
hormone transport GO:0009914 2 0.027
protein import into nucleus GO:0006606 3 0.027
gland development GO:0048732 143 0.027
response to hexose GO:0009746 3 0.027
death GO:0016265 121 0.027
Human
female gonad development GO:0008585 4 0.027
axonogenesis GO:0007409 152 0.026
hepaticobiliary system development GO:0061008 98 0.026
intracellular transport GO:0046907 32 0.026
phosphorus metabolic process GO:0006793 109 0.026
negative regulation of signal transduction GO:0009968 94 0.026
peptide transport GO:0015833 1 0.026
viral process GO:0016032 1 0.026
regulation of cell activation GO:0050865 1 0.026
regulation of catalytic activity GO:0050790 55 0.026
Human
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
positive regulation of immune effector process GO:0002699 3 0.026
synaptic vesicle localization GO:0097479 1 0.026
regulation of cytokine production GO:0001817 3 0.026
gastrulation GO:0007369 208 0.025
regulation of dendrite morphogenesis GO:0048814 3 0.025
cell motility GO:0048870 244 0.025
carbohydrate homeostasis GO:0033500 1 0.025
positive regulation of muscle organ development GO:0048636 1 0.025
positive regulation of secretion by cell GO:1903532 1 0.025
protein localization to plasma membrane GO:0072659 1 0.025
modulation by virus of host morphology or physiology GO:0019048 1 0.025
mitotic dna integrity checkpoint GO:0044774 4 0.025
nuclear import GO:0051170 3 0.025
regulation of primary metabolic process GO:0080090 311 0.025
Human
calcium ion import GO:0070509 4 0.025
establishment of protein localization to plasma membrane GO:0090002 1 0.025
muscle organ development GO:0007517 101 0.025
cortical cytoskeleton organization GO:0030865 1 0.025
locomotor rhythm GO:0045475 3 0.025
negative regulation of protein complex assembly GO:0031333 1 0.025
proteolysis GO:0006508 38 0.025
Human
regulation of intracellular signal transduction GO:1902531 57 0.024
negative regulation of metabolic process GO:0009892 86 0.024
programmed cell death GO:0012501 119 0.024
Human
axon development GO:0061564 166 0.024
regulation of endopeptidase activity GO:0052548 23 0.024
Human
organic cyclic compound metabolic process GO:1901360 301 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
regulation of organelle assembly GO:1902115 4 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
endosomal transport GO:0016197 2 0.024
regulation of carbohydrate metabolic process GO:0006109 4 0.024
cell cycle GO:0007049 93 0.024
negative regulation of protein localization to nucleus GO:1900181 2 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
ras protein signal transduction GO:0007265 7 0.024
interspecies interaction between organisms GO:0044419 4 0.024
stem cell proliferation GO:0072089 4 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
regulation of reproductive process GO:2000241 4 0.023
response to monosaccharide GO:0034284 3 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of binding GO:0051098 3 0.023
organelle localization GO:0051640 49 0.023
zymogen activation GO:0031638 3 0.023
Human
forebrain development GO:0030900 96 0.023
positive regulation of carbohydrate metabolic process GO:0045913 1 0.023
negative regulation of intracellular protein transport GO:0090317 3 0.023
actin filament based process GO:0030029 64 0.023
regulation of blood pressure GO:0008217 1 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
cell matrix adhesion GO:0007160 4 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.022
Human
development of primary female sexual characteristics GO:0046545 4 0.022
response to uv GO:0009411 3 0.022
stem cell division GO:0017145 1 0.022
developmental cell growth GO:0048588 52 0.022
positive regulation of cell adhesion GO:0045785 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
cell substrate adhesion GO:0031589 4 0.022
negative regulation of protein import into nucleus GO:0042308 2 0.022
regulation of molecular function GO:0065009 70 0.022
Human
single organism organelle organization GO:1902589 199 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
axon guidance GO:0007411 86 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
apoptotic process involved in development GO:1902742 2 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.021
meiotic cell cycle process GO:1903046 3 0.021
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.021
hemopoiesis GO:0030097 183 0.021
regulation of response to extracellular stimulus GO:0032104 1 0.021
regulation of programmed cell death GO:0043067 101 0.021
Human
neuroblast proliferation GO:0007405 2 0.021
taxis GO:0042330 109 0.021
multi organism process GO:0051704 134 0.021
regulation of gtp catabolic process GO:0033124 2 0.021
positive regulation of neuron apoptotic process GO:0043525 1 0.021
protein secretion GO:0009306 1 0.021
cellular response to hormone stimulus GO:0032870 39 0.021
cell killing GO:0001906 2 0.021
establishment of localization in cell GO:0051649 77 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of phosphorus metabolic process GO:0051174 43 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
regulation of autophagy GO:0010506 3 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.020
response to corticosteroid GO:0031960 1 0.020
regulation of gene expression GO:0010468 265 0.020
regulation of cell death GO:0010941 103 0.020
Human
lateral inhibition GO:0046331 1 0.020
hormone secretion GO:0046879 2 0.020
negative regulation of map kinase activity GO:0043407 2 0.020
pyruvate metabolic process GO:0006090 1 0.020
germ line stem cell maintenance GO:0030718 2 0.020
muscle structure development GO:0061061 196 0.020
liver development GO:0001889 96 0.020
embryonic skeletal system development GO:0048706 97 0.020
positive regulation of cell communication GO:0010647 56 0.020
spindle assembly GO:0051225 2 0.020
membrane fusion GO:0061025 2 0.020
regulation of nervous system development GO:0051960 90 0.020
stem cell differentiation GO:0048863 117 0.019
regulation of cellular component organization GO:0051128 86 0.019
motor neuron axon guidance GO:0008045 23 0.019
wnt signaling pathway GO:0016055 80 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
blood vessel development GO:0001568 246 0.019
negative regulation of developmental process GO:0051093 65 0.019
vasculature development GO:0001944 278 0.019
protein dephosphorylation GO:0006470 3 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
negative regulation of tor signaling GO:0032007 2 0.019
regulation of tube size GO:0035150 2 0.018
tissue remodeling GO:0048771 4 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
regulation of cell matrix adhesion GO:0001952 1 0.018
peptidyl serine modification GO:0018209 2 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
synaptic vesicle transport GO:0048489 1 0.018
response to external biotic stimulus GO:0043207 97 0.018
embryonic organ development GO:0048568 381 0.018
positive regulation of biosynthetic process GO:0009891 68 0.018
skeletal muscle organ development GO:0060538 78 0.018
regulation of proteolysis GO:0030162 24 0.018
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
negative chemotaxis GO:0050919 1 0.017
response to light stimulus GO:0009416 46 0.017
multi organism cellular process GO:0044764 2 0.017
regulation of cysteine type endopeptidase activity GO:2000116 21 0.017
Human
positive regulation of secretion GO:0051047 1 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
axon extension GO:0048675 45 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
protein complex subunit organization GO:0071822 46 0.017
regulation of gtpase activity GO:0043087 2 0.017
response to carbohydrate GO:0009743 3 0.017
response to drug GO:0042493 3 0.017
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.017
cytoplasm organization GO:0007028 4 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
circadian sleep wake cycle sleep GO:0050802 1 0.017
chemotaxis GO:0006935 104 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.017
tube closure GO:0060606 1 0.017
positive regulation of cellular protein metabolic process GO:0032270 22 0.017
Human
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
fertilization GO:0009566 3 0.017
response to biotic stimulus GO:0009607 97 0.017
determination of left right symmetry GO:0007368 179 0.017
regulation of filopodium assembly GO:0051489 2 0.016
canonical wnt signaling pathway GO:0060070 48 0.016
regulation of rho protein signal transduction GO:0035023 2 0.016
sex determination GO:0007530 1 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
negative regulation of kinase activity GO:0033673 4 0.016
positive regulation of protein polymerization GO:0032273 2 0.016
protein homooligomerization GO:0051260 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.016
skeletal system development GO:0001501 181 0.016
regulation of inflammatory response GO:0050727 2 0.016
regulation of metal ion transport GO:0010959 4 0.016
neurological system process GO:0050877 62 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
interaction with host GO:0051701 4 0.016
protein polymerization GO:0051258 4 0.016
epithelial cell differentiation GO:0030855 116 0.016
response to glucocorticoid GO:0051384 1 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.015
somatic muscle development GO:0007525 4 0.015
response to ketone GO:1901654 1 0.015
leukocyte differentiation GO:0002521 25 0.015
negative regulation of stem cell differentiation GO:2000737 2 0.015
atp catabolic process GO:0006200 4 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
regulation of wound healing GO:0061041 2 0.015
positive regulation of notch signaling pathway GO:0045747 3 0.015
regulation of cell shape GO:0008360 1 0.015
cellular component disassembly GO:0022411 1 0.015
spermatid development GO:0007286 2 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
regeneration GO:0031099 91 0.015
microtubule based movement GO:0007018 33 0.015
regulation of oocyte development GO:0060281 3 0.015
cell growth GO:0016049 57 0.015
regulation of hormone secretion GO:0046883 2 0.015
p38mapk cascade GO:0038066 1 0.015
regulation of jak stat cascade GO:0046425 3 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of cellular component size GO:0032535 30 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
spermatid differentiation GO:0048515 2 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
positive regulation of neuron death GO:1901216 1 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of protein binding GO:0043393 3 0.014
female meiotic division GO:0007143 2 0.014
regulation of protein polymerization GO:0032271 2 0.014
digestive tract development GO:0048565 265 0.014
regulation of neurogenesis GO:0050767 87 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of jun kinase activity GO:0043506 3 0.014
regulation of cell projection organization GO:0031344 44 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
response to hormone GO:0009725 48 0.014
positive regulation of cell death GO:0010942 29 0.014
Human
small gtpase mediated signal transduction GO:0007264 8 0.014
organic acid metabolic process GO:0006082 31 0.014
positive regulation of metabolic process GO:0009893 108 0.014
Human
protein phosphorylation GO:0006468 47 0.014
nuclear export GO:0051168 1 0.014
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.014
synapsis GO:0007129 1 0.014
circadian sleep wake cycle process GO:0022410 2 0.014
regulation of response to stress GO:0080134 36 0.014
regulation of anatomical structure size GO:0090066 33 0.014
type b pancreatic cell development GO:0003323 4 0.014
response to oxygen containing compound GO:1901700 55 0.014
response to nutrient GO:0007584 3 0.014
killing of cells of other organism GO:0031640 1 0.014
blood vessel morphogenesis GO:0048514 216 0.014
activation of jun kinase activity GO:0007257 2 0.014
circadian sleep wake cycle GO:0042745 2 0.014
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.014
regulation of dna replication GO:0006275 3 0.014
circulatory system process GO:0003013 87 0.014

apaf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
disease of metabolism DOID:0014667 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
cancer DOID:162 0 0.020
muscle tissue disease DOID:66 0 0.019
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
musculoskeletal system disease DOID:17 0 0.019
inherited metabolic disorder DOID:655 0 0.015