Danio rerio

0 known processes

gch1

GTP cyclohydrolase 1

(Aliases: gch1a,fc16b10,zgc:195269,wu:fc16b10)

gch1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin polymerization or depolymerization GO:0008154 2 0.052
gtp metabolic process GO:0046039 4 0.052
larval development GO:0002164 2 0.048
neuron development GO:0048666 262 0.047
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.047
regulation of synapse organization GO:0050807 3 0.045
regulation of biological quality GO:0065008 263 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
regulation of multicellular organismal development GO:2000026 223 0.042
central nervous system development GO:0007417 387 0.040
negative regulation of cellular process GO:0048523 283 0.040
regulation of protein complex assembly GO:0043254 3 0.038
positive regulation of protein complex assembly GO:0031334 2 0.038
regulation of synapse assembly GO:0051963 3 0.036
amine metabolic process GO:0009308 2 0.036
digestive system development GO:0055123 289 0.033
g protein coupled receptor signaling pathway GO:0007186 74 0.033
chordate embryonic development GO:0043009 271 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
negative regulation of synapse assembly GO:0051964 2 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
cell part morphogenesis GO:0032990 246 0.030
neuron projection development GO:0031175 180 0.029
neuron differentiation GO:0030182 353 0.029
sensory organ development GO:0007423 393 0.029
cell morphogenesis GO:0000902 289 0.029
guanosine containing compound metabolic process GO:1901068 4 0.028
cellular response to organic substance GO:0071310 105 0.028
cellular amine metabolic process GO:0044106 2 0.028
positive regulation of transport GO:0051050 2 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.027
generation of neurons GO:0048699 385 0.027
cellular response to external stimulus GO:0071496 2 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
tube morphogenesis GO:0035239 349 0.026
cell matrix adhesion GO:0007160 4 0.026
single organism transport GO:0044765 206 0.026
response to chemical GO:0042221 320 0.026
cellular component morphogenesis GO:0032989 336 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
negative regulation of biological process GO:0048519 304 0.025
cellular component biogenesis GO:0044085 178 0.025
cation transmembrane transport GO:0098655 65 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
regulation of reproductive process GO:2000241 4 0.025
gtp catabolic process GO:0006184 2 0.025
cell substrate adhesion GO:0031589 4 0.024
transmembrane transport GO:0055085 120 0.024
maintenance of location GO:0051235 4 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
protein polymerization GO:0051258 4 0.024
gastrulation GO:0007369 208 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of cell shape GO:0008360 1 0.023
forebrain cell migration GO:0021885 1 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
cellular response to extracellular stimulus GO:0031668 2 0.022
embryonic organ development GO:0048568 381 0.022
brain development GO:0007420 293 0.022
positive regulation of catabolic process GO:0009896 4 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
regulation of autophagy GO:0010506 3 0.022
cellular component assembly GO:0022607 170 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cell projection organization GO:0030030 284 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
small molecule metabolic process GO:0044281 77 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
regulation of cell projection assembly GO:0060491 4 0.021
ion transmembrane transport GO:0034220 91 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of transporter activity GO:0032409 2 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell projection morphogenesis GO:0048858 244 0.021
head development GO:0060322 303 0.021
regulation of developmental process GO:0050793 247 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
skeletal muscle organ development GO:0060538 78 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
protein localization to nucleus GO:0034504 3 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
adult behavior GO:0030534 2 0.020
striated muscle tissue development GO:0014706 110 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
regulation of cell communication GO:0010646 232 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of protein catabolic process GO:0042176 1 0.020
lipid storage GO:0019915 1 0.020
cellular ketone metabolic process GO:0042180 11 0.020
eye development GO:0001654 277 0.019
response to organic substance GO:0010033 153 0.019
peptidyl threonine phosphorylation GO:0018107 1 0.019
digestive tract development GO:0048565 265 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
digestive tract morphogenesis GO:0048546 231 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
organelle organization GO:0006996 227 0.019
negative regulation of response to stimulus GO:0048585 104 0.019
regulation of response to stimulus GO:0048583 269 0.019
gastrulation with mouth forming second GO:0001702 44 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
regulation of metal ion transport GO:0010959 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
autophagy GO:0006914 4 0.018
single organism metabolic process GO:0044710 217 0.018
signal transduction GO:0007165 455 0.018
carbohydrate derivative biosynthetic process GO:1901137 43 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
locomotion GO:0040011 313 0.018
somatic muscle development GO:0007525 4 0.018
regulation of oocyte development GO:0060281 3 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
negative regulation of catabolic process GO:0009895 3 0.018
cognition GO:0050890 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
phagocytosis GO:0006909 3 0.017
regulation of dendrite development GO:0050773 3 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
actin filament polymerization GO:0030041 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
regulation of signaling GO:0023051 235 0.017
positive regulation of histone modification GO:0031058 1 0.017
regulation of cytokine production GO:0001817 3 0.017
cytokinesis GO:0000910 3 0.017
transcription dna templated GO:0006351 181 0.017
neuron projection morphogenesis GO:0048812 161 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
segmentation GO:0035282 97 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of calcium ion transport GO:0051924 2 0.016
organic acid catabolic process GO:0016054 3 0.016
muscle structure development GO:0061061 196 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
biosynthetic process GO:0009058 294 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.016
peptidyl threonine modification GO:0018210 1 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
inorganic cation transmembrane transport GO:0098662 50 0.016
response to external stimulus GO:0009605 264 0.016
muscle tissue development GO:0060537 110 0.016
centrosome organization GO:0051297 1 0.016
multi organism cellular process GO:0044764 2 0.016
heart development GO:0007507 313 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
blood vessel development GO:0001568 246 0.016
microtubule organizing center organization GO:0031023 1 0.016
lateral inhibition GO:0046331 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
single organism localization GO:1902578 225 0.015
regulation of signal transduction GO:0009966 225 0.015
nephron tubule morphogenesis GO:0072078 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
positive regulation of immune effector process GO:0002699 3 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
cellular response to starvation GO:0009267 1 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
convergent extension GO:0060026 118 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of binding GO:0051098 3 0.015
single organism organelle organization GO:1902589 199 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
dopamine metabolic process GO:0042417 2 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of blood vessel size GO:0050880 2 0.015
regionalization GO:0003002 274 0.015
negative regulation of cell communication GO:0010648 96 0.015
positive regulation of cellular process GO:0048522 201 0.015
negative regulation of signaling GO:0023057 96 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of tube size GO:0035150 2 0.014
superoxide metabolic process GO:0006801 2 0.014
regulation of primary metabolic process GO:0080090 311 0.014
regulation of programmed cell death GO:0043067 101 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
golgi vesicle transport GO:0048193 3 0.014
multicellular organism growth GO:0035264 4 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
stem cell proliferation GO:0072089 4 0.014
negative regulation of signal transduction GO:0009968 94 0.014
outflow tract morphogenesis GO:0003151 1 0.014
regulation of filopodium assembly GO:0051489 2 0.014
response to hexose GO:0009746 3 0.014
response to stress GO:0006950 263 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
protein import GO:0017038 3 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
determination of bilateral symmetry GO:0009855 204 0.014
peptidyl serine modification GO:0018209 2 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.013
cell motility GO:0048870 244 0.013
organic substance biosynthetic process GO:1901576 289 0.013
single organism membrane fusion GO:0044801 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
transport GO:0006810 220 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
response to carbohydrate GO:0009743 3 0.013
heterocycle metabolic process GO:0046483 290 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
periodic partitioning GO:0007365 1 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
regulation of metabolic process GO:0019222 359 0.013
energy reserve metabolic process GO:0006112 2 0.013
protein metabolic process GO:0019538 183 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
establishment of localization GO:0051234 244 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
regulation of cell development GO:0060284 100 0.013
taxis GO:0042330 109 0.013
axonogenesis GO:0007409 152 0.013
nitric oxide biosynthetic process GO:0006809 2 0.013
lipid homeostasis GO:0055088 3 0.013
regulation of cell activation GO:0050865 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
endosomal transport GO:0016197 2 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
nuclear transport GO:0051169 4 0.013
intracellular signal transduction GO:0035556 85 0.013
positive regulation of cell cycle GO:0045787 3 0.013
gland development GO:0048732 143 0.013
female gonad development GO:0008585 4 0.013
system process GO:0003008 185 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
catecholamine metabolic process GO:0006584 2 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
nucleoside triphosphate biosynthetic process GO:0009142 2 0.012
muscle organ development GO:0007517 101 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of apoptotic process GO:0042981 98 0.012
membrane lipid biosynthetic process GO:0046467 2 0.012
regulation of sodium ion transport GO:0002028 2 0.012
regulation of gene expression GO:0010468 265 0.012
alcohol biosynthetic process GO:0046165 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
macroautophagy GO:0016236 1 0.012
protein complex disassembly GO:0043241 1 0.012
membrane fusion GO:0061025 2 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
regulation of protein transport GO:0051223 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
positive regulation of reproductive process GO:2000243 2 0.012
cell projection assembly GO:0030031 64 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
death GO:0016265 121 0.012
atp catabolic process GO:0006200 4 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
response to alkaloid GO:0043279 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
axonal defasciculation GO:0007414 2 0.012
protein dephosphorylation GO:0006470 3 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
regulation of organelle assembly GO:1902115 4 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
cell migration GO:0016477 237 0.012
embryonic skeletal system development GO:0048706 97 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
skeletal system morphogenesis GO:0048705 102 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
sensory perception of smell GO:0007608 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
apoptotic process GO:0006915 116 0.011
glucose homeostasis GO:0042593 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
axon development GO:0061564 166 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of cell differentiation GO:0045595 142 0.011
regulation of bone mineralization GO:0030500 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
protein acetylation GO:0006473 2 0.011
cell death GO:0008219 121 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
peptide transport GO:0015833 1 0.011
response to drug GO:0042493 3 0.011
regulation of cell death GO:0010941 103 0.011
neuroblast proliferation GO:0007405 2 0.011
ear morphogenesis GO:0042471 64 0.011
nuclear import GO:0051170 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of membrane potential GO:0042391 23 0.011
cellular component movement GO:0006928 335 0.011
localization of cell GO:0051674 244 0.011
positive regulation of blood circulation GO:1903524 2 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
aging GO:0007568 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
action potential GO:0001508 19 0.011
rna metabolic process GO:0016070 219 0.011
cytoplasm organization GO:0007028 4 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
mechanosensory behavior GO:0007638 2 0.010
heart looping GO:0001947 94 0.010
cell cycle arrest GO:0007050 1 0.010
exocytosis GO:0006887 1 0.010
regulation of nervous system development GO:0051960 90 0.010
ameboidal type cell migration GO:0001667 143 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
protein acylation GO:0043543 3 0.010
response to glucose GO:0009749 3 0.010
compound eye development GO:0048749 2 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
ion transport GO:0006811 114 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010

gch1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010