Danio rerio

0 known processes

tlk2

tousled-like kinase 2

(Aliases: wu:fi16h09,MGC136697,zgc:136697,wu:fi30g12,MGC173515,KIAA0137)

tlk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 3 0.267
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.120
Human
regulation of protein transport GO:0051223 3 0.105
regulation of intracellular protein transport GO:0033157 3 0.102
positive regulation of transport GO:0051050 2 0.075
regulation of establishment of protein localization GO:0070201 4 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.058
Human
regulation of protein targeting GO:1903533 2 0.049
proteasomal protein catabolic process GO:0010498 2 0.048
Human
aging GO:0007568 2 0.044
establishment of protein localization to organelle GO:0072594 4 0.042
protein localization to nucleus GO:0034504 3 0.041
modification dependent macromolecule catabolic process GO:0043632 3 0.039
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.038
protein targeting to nucleus GO:0044744 3 0.037
regulation of cytoplasmic transport GO:1903649 4 0.037
system process GO:0003008 185 0.036
nucleocytoplasmic transport GO:0006913 4 0.036
negative regulation of gliogenesis GO:0014014 1 0.036
single organism nuclear import GO:1902593 3 0.035
nuclear import GO:0051170 3 0.034
gene expression GO:0010467 252 0.032
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
organelle assembly GO:0070925 110 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
protein import GO:0017038 3 0.029
glial cell proliferation GO:0014009 4 0.029
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.029
regulation of protein import into nucleus GO:0042306 2 0.029
cognition GO:0050890 1 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
regulation of response to nutrient levels GO:0032107 1 0.028
cellular protein catabolic process GO:0044257 4 0.027
Human
negative regulation of protein transport GO:0051224 3 0.027
negative regulation of intracellular transport GO:0032387 3 0.027
regulation of organelle assembly GO:1902115 4 0.026
maintenance of location GO:0051235 4 0.023
protein import into nucleus GO:0006606 3 0.023
multicellular organism growth GO:0035264 4 0.023
negative regulation of intracellular protein transport GO:0090317 3 0.023
muscle cell differentiation GO:0042692 139 0.023
single organism transport GO:0044765 206 0.023
negative regulation of protein import into nucleus GO:0042308 2 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
larval development GO:0002164 2 0.021
establishment of localization GO:0051234 244 0.020
neurological system process GO:0050877 62 0.019
peptide transport GO:0015833 1 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.018
cell part morphogenesis GO:0032990 246 0.018
nuclear transport GO:0051169 4 0.018
stem cell maintenance GO:0019827 4 0.017
striated muscle cell differentiation GO:0051146 129 0.017
cellular localization GO:0051641 97 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
nucleic acid templated transcription GO:0097659 181 0.017
rna localization GO:0006403 4 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
female gonad development GO:0008585 4 0.016
regulation of cell activation GO:0050865 1 0.016
cellular biosynthetic process GO:0044249 286 0.016
muscle structure development GO:0061061 196 0.016
biosynthetic process GO:0009058 294 0.016
meiotic chromosome segregation GO:0045132 3 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
positive regulation of catabolic process GO:0009896 4 0.015
regulation of circadian rhythm GO:0042752 4 0.015
cell motility GO:0048870 244 0.015
regulation of cytokine production GO:0001817 3 0.015
regionalization GO:0003002 274 0.015
cellular response to external stimulus GO:0071496 2 0.015
protein metabolic process GO:0019538 183 0.015
Human
cellular response to extracellular stimulus GO:0031668 2 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
organic substance transport GO:0071702 58 0.014
neuron differentiation GO:0030182 353 0.014
muscle cell development GO:0055001 115 0.014
cell projection morphogenesis GO:0048858 244 0.014
cellular component morphogenesis GO:0032989 336 0.014
rna biosynthetic process GO:0032774 181 0.014
translational initiation GO:0006413 3 0.014
signal transduction GO:0007165 455 0.014
Human
regulation of reproductive process GO:2000241 4 0.014
negative regulation of cellular process GO:0048523 283 0.014
Human
regulation of dendrite development GO:0050773 3 0.014
response to chemical GO:0042221 320 0.014
transport GO:0006810 220 0.014
regulation of multicellular organism growth GO:0040014 4 0.013
mesenchyme development GO:0060485 127 0.013
regulation of biosynthetic process GO:0009889 250 0.013
meiotic nuclear division GO:0007126 4 0.013
positive regulation of cell cycle GO:0045787 3 0.013
macromolecule localization GO:0033036 54 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
transcription dna templated GO:0006351 181 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
Human
centrosome cycle GO:0007098 1 0.013
phagocytosis GO:0006909 3 0.012
organic substance biosynthetic process GO:1901576 289 0.012
protein polyubiquitination GO:0000209 4 0.012
tissue remodeling GO:0048771 4 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
regulation of transcription dna templated GO:0006355 213 0.012
cell death GO:0008219 121 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
single organism localization GO:1902578 225 0.012
angiogenesis GO:0001525 158 0.012
positive regulation of immune effector process GO:0002699 3 0.012
mrna stabilization GO:0048255 4 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
negative regulation of multi organism process GO:0043901 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
amine metabolic process GO:0009308 2 0.012
death GO:0016265 121 0.012
positive regulation of secretion GO:0051047 1 0.012
meiotic cell cycle process GO:1903046 3 0.011
developmental programmed cell death GO:0010623 4 0.011
negative regulation of biological process GO:0048519 304 0.011
Human
protein complex localization GO:0031503 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
cell projection organization GO:0030030 284 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Human
anterior posterior pattern specification GO:0009952 152 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of protein complex assembly GO:0043254 3 0.011
regulation of biological quality GO:0065008 263 0.011
tube morphogenesis GO:0035239 349 0.010
dna templated transcription elongation GO:0006354 3 0.010
nuclear export GO:0051168 1 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
axon development GO:0061564 166 0.010
cellular amine metabolic process GO:0044106 2 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
chromosome organization GO:0051276 31 0.010
Human
blood vessel development GO:0001568 246 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
neuron development GO:0048666 262 0.010
regulation of cell development GO:0060284 100 0.010

tlk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011