Danio rerio

43 known processes

LOC566040

protein notum homolog

LOC566040 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of location GO:0051235 4 0.131
larval development GO:0002164 2 0.111
regulation of metabolic process GO:0019222 359 0.061
heart development GO:0007507 313 0.061
nucleoside monophosphate catabolic process GO:0009125 4 0.060
aging GO:0007568 2 0.058
sensory organ development GO:0007423 393 0.056
eye development GO:0001654 277 0.054
skeletal muscle organ development GO:0060538 78 0.054
response to alkaloid GO:0043279 2 0.052
regulation of multicellular organism growth GO:0040014 4 0.051
muscle structure development GO:0061061 196 0.051
cellular nitrogen compound metabolic process GO:0034641 290 0.049
multicellular organism growth GO:0035264 4 0.048
cell migration GO:0016477 237 0.046
negative regulation of biological process GO:0048519 304 0.044
response to chemical GO:0042221 320 0.044
cellular component movement GO:0006928 335 0.040
cellular component morphogenesis GO:0032989 336 0.039
skeletal system development GO:0001501 181 0.039
embryonic cranial skeleton morphogenesis GO:0048701 90 0.038
cell projection organization GO:0030030 284 0.038
angiogenesis GO:0001525 158 0.038
guanosine containing compound catabolic process GO:1901069 2 0.037
actin filament based movement GO:0030048 1 0.037
generation of neurons GO:0048699 385 0.037
establishment of protein localization to organelle GO:0072594 4 0.036
regulation of biological quality GO:0065008 263 0.036
regulation of signal transduction GO:0009966 225 0.036
cognition GO:0050890 1 0.035
organic substance biosynthetic process GO:1901576 289 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
striated muscle tissue development GO:0014706 110 0.035
chordate embryonic development GO:0043009 271 0.034
mitochondrion organization GO:0007005 4 0.034
neuron development GO:0048666 262 0.033
centrosome cycle GO:0007098 1 0.033
embryonic organ development GO:0048568 381 0.033
muscle cell differentiation GO:0042692 139 0.033
tube morphogenesis GO:0035239 349 0.033
somatic muscle development GO:0007525 4 0.032
sleep GO:0030431 1 0.032
lipid storage GO:0019915 1 0.032
skeletal muscle tissue development GO:0007519 67 0.031
regulation of cell communication GO:0010646 232 0.031
cytoskeleton dependent cytokinesis GO:0061640 3 0.031
cellular biosynthetic process GO:0044249 286 0.031
amine metabolic process GO:0009308 2 0.030
response to drug GO:0042493 3 0.030
cellular response to external stimulus GO:0071496 2 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
heterocycle metabolic process GO:0046483 290 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
protein localization to nucleus GO:0034504 3 0.029
positive regulation of catabolic process GO:0009896 4 0.029
axonogenesis GO:0007409 152 0.029
blood vessel development GO:0001568 246 0.029
cellular ketone metabolic process GO:0042180 11 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
nuclear import GO:0051170 3 0.028
cell morphogenesis GO:0000902 289 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
positive regulation of transport GO:0051050 2 0.027
vasculature development GO:0001944 278 0.027
atp catabolic process GO:0006200 4 0.027
gene expression GO:0010467 252 0.027
purine nucleoside monophosphate catabolic process GO:0009128 4 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
myofibril assembly GO:0030239 48 0.027
gtp metabolic process GO:0046039 4 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.026
cellular component disassembly GO:0022411 1 0.026
cell motility GO:0048870 244 0.026
nucleocytoplasmic transport GO:0006913 4 0.025
regulation of synaptic plasticity GO:0048167 1 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.025
regulation of cytokine production GO:0001817 3 0.025
response to amphetamine GO:0001975 1 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
cellular protein catabolic process GO:0044257 4 0.025
muscle tissue development GO:0060537 110 0.025
sequestering of metal ion GO:0051238 3 0.024
phagocytosis GO:0006909 3 0.024
protein stabilization GO:0050821 2 0.024
compound eye development GO:0048749 2 0.024
regulation of blood pressure GO:0008217 1 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
protein polymerization GO:0051258 4 0.023
regulation of cell activation GO:0050865 1 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.023
urogenital system development GO:0001655 97 0.023
ameboidal type cell migration GO:0001667 143 0.023
blood vessel morphogenesis GO:0048514 216 0.022
system process GO:0003008 185 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
heart morphogenesis GO:0003007 156 0.022
positive regulation of epithelial cell migration GO:0010634 2 0.022
protein import GO:0017038 3 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
biosynthetic process GO:0009058 294 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
muscle organ development GO:0007517 101 0.022
notochord development GO:0030903 54 0.021
meiotic cell cycle process GO:1903046 3 0.021
cellular amine metabolic process GO:0044106 2 0.021
regulation of primary metabolic process GO:0080090 311 0.021
negative regulation of protein transport GO:0051224 3 0.021
gtp catabolic process GO:0006184 2 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
epithelial cell differentiation GO:0030855 116 0.021
regulation of protein polymerization GO:0032271 2 0.021
neuroblast differentiation GO:0014016 1 0.021
heart process GO:0003015 71 0.021
cellular response to nutrient levels GO:0031669 2 0.021
actin polymerization or depolymerization GO:0008154 2 0.020
macroautophagy GO:0016236 1 0.020
transcription dna templated GO:0006351 181 0.020
activation of mapk activity GO:0000187 3 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
response to stress GO:0006950 263 0.020
cytokinesis GO:0000910 3 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of gene expression GO:0010468 265 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
regulation of cell shape GO:0008360 1 0.020
voluntary skeletal muscle contraction GO:0003010 4 0.020
protein targeting to nucleus GO:0044744 3 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of binding GO:0051098 3 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
regulation of muscle contraction GO:0006937 3 0.019
regulation of response to stimulus GO:0048583 269 0.019
regulation of circadian rhythm GO:0042752 4 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
transport GO:0006810 220 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of receptor activity GO:0010469 2 0.019
positive regulation of cell cycle GO:0045787 3 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular component assembly GO:0022607 170 0.019
nuclear transport GO:0051169 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
zymogen activation GO:0031638 3 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of metal ion transport GO:0010959 4 0.018
epidermal cell fate specification GO:0009957 4 0.018
sequestering of calcium ion GO:0051208 3 0.018
ventricular cardiac muscle tissue development GO:0003229 3 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
rna biosynthetic process GO:0032774 181 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
regulation of protein complex assembly GO:0043254 3 0.018
guanosine containing compound metabolic process GO:1901068 4 0.017
post embryonic organ development GO:0048569 4 0.017
blood circulation GO:0008015 87 0.017
stem cell fate commitment GO:0048865 1 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
extracellular matrix organization GO:0030198 27 0.017
cation transport GO:0006812 81 0.017
interspecies interaction between organisms GO:0044419 4 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
digestive system development GO:0055123 289 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
single organism nuclear import GO:1902593 3 0.017
multi organism cellular process GO:0044764 2 0.017
protein acetylation GO:0006473 2 0.017
outflow tract morphogenesis GO:0003151 1 0.017
membrane invagination GO:0010324 1 0.017
neuron projection morphogenesis GO:0048812 161 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
microtubule organizing center organization GO:0031023 1 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
positive regulation of cellular process GO:0048522 201 0.017
cellular response to starvation GO:0009267 1 0.017
ion transport GO:0006811 114 0.016
meiotic chromosome segregation GO:0045132 3 0.016
lens fiber cell development GO:0070307 3 0.016
single organism membrane fusion GO:0044801 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
apoptotic process involved in development GO:1902742 2 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
endosomal transport GO:0016197 2 0.016
positive regulation of gtpase activity GO:0043547 1 0.016
rna metabolic process GO:0016070 219 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
embryonic skeletal system development GO:0048706 97 0.015
establishment of localization GO:0051234 244 0.015
regulation of transporter activity GO:0032409 2 0.015
response to amine GO:0014075 1 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
homeostatic process GO:0042592 142 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
negative regulation of intracellular transport GO:0032387 3 0.015
centrosome organization GO:0051297 1 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
positive regulation of endothelial cell migration GO:0010595 2 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
regulation of signaling GO:0023051 235 0.015
regulation of locomotion GO:0040012 55 0.015
regulation of programmed cell death GO:0043067 101 0.015
macromolecular complex disassembly GO:0032984 1 0.015
myotube cell development GO:0014904 35 0.015
pole plasm assembly GO:0007315 4 0.015
antimicrobial humoral response GO:0019730 2 0.015
cellular response to organic cyclic compound GO:0071407 38 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
regulation of growth rate GO:0040009 1 0.015
single organism transport GO:0044765 206 0.015
adult behavior GO:0030534 2 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.015
protein acylation GO:0043543 3 0.015
immune system development GO:0002520 191 0.014
nucleoside phosphate metabolic process GO:0006753 28 0.014
cell death GO:0008219 121 0.014
axon development GO:0061564 166 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
skeletal muscle contraction GO:0003009 5 0.014
nucleic acid templated transcription GO:0097659 181 0.014
regulation of gtpase activity GO:0043087 2 0.014
response to organic substance GO:0010033 153 0.014
striated muscle contraction GO:0006941 12 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
hormone transport GO:0009914 2 0.014
regulation of cell death GO:0010941 103 0.014
striated muscle cell development GO:0055002 108 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
leukocyte proliferation GO:0070661 1 0.014
viral process GO:0016032 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
positive regulation of blood circulation GO:1903524 2 0.014
signal transduction GO:0007165 455 0.014
developmental programmed cell death GO:0010623 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
mononuclear cell proliferation GO:0032943 1 0.013
positive regulation of biological process GO:0048518 253 0.013
skin development GO:0043588 54 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
forebrain cell migration GO:0021885 1 0.013
skeletal muscle thin filament assembly GO:0030240 4 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
cellular protein complex assembly GO:0043623 19 0.013
regulation of mrna processing GO:0050684 3 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
regulation of localization GO:0032879 104 0.013
immune system process GO:0002376 241 0.013
regulation of organ growth GO:0046620 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
regulation of wound healing GO:0061041 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
skeletal myofibril assembly GO:0014866 7 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
actin mediated cell contraction GO:0070252 1 0.013
autophagy GO:0006914 4 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
localization of cell GO:0051674 244 0.013
response to topologically incorrect protein GO:0035966 2 0.013
camera type eye development GO:0043010 222 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
apoptotic process GO:0006915 116 0.013
response to carbohydrate GO:0009743 3 0.013
negative regulation of wnt signaling pathway GO:0030178 30 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
adherens junction assembly GO:0034333 1 0.012
positive regulation of cytokine production GO:0001819 2 0.012
heart contraction GO:0060047 71 0.012
negative regulation of catabolic process GO:0009895 3 0.012
spermatid differentiation GO:0048515 2 0.012
locomotor rhythm GO:0045475 3 0.012
gland development GO:0048732 143 0.012
wnt signaling pathway GO:0016055 80 0.012
positive regulation of cell activation GO:0050867 1 0.012
meiotic nuclear division GO:0007126 4 0.012
membrane fusion GO:0061025 2 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
lens fiber cell morphogenesis GO:0070309 3 0.012
intracellular mrna localization GO:0008298 1 0.012
cartilage development GO:0051216 96 0.012
positive regulation of multi organism process GO:0043902 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
b cell activation GO:0042113 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
neuron projection development GO:0031175 180 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of protein catabolic process GO:0042176 1 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
actin filament polymerization GO:0030041 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of hormone secretion GO:0046883 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
kidney development GO:0001822 92 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
regulation of axonogenesis GO:0050770 32 0.011
single organism localization GO:1902578 225 0.011
stem cell maintenance GO:0019827 4 0.011
smooth muscle contraction GO:0006939 2 0.011
twitch skeletal muscle contraction GO:0014721 4 0.011
olfactory lobe development GO:0021988 4 0.011
digestive tract morphogenesis GO:0048546 231 0.011
cell part morphogenesis GO:0032990 246 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
cellular localization GO:0051641 97 0.011
muscle system process GO:0003012 20 0.011
regulation of inflammatory response GO:0050727 2 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
regionalization GO:0003002 274 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
cellular protein complex disassembly GO:0043624 1 0.011
response to monosaccharide GO:0034284 3 0.011
stem cell division GO:0017145 1 0.011
cytokinetic process GO:0032506 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
endocrine system development GO:0035270 65 0.011
organelle organization GO:0006996 227 0.011
positive regulation of camp metabolic process GO:0030816 2 0.011
energy reserve metabolic process GO:0006112 2 0.011
axis specification GO:0009798 43 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
response to external stimulus GO:0009605 264 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cyclic purine nucleotide metabolic process GO:0052652 18 0.011
regulation of protein binding GO:0043393 3 0.011
cellular response to organic substance GO:0071310 105 0.011
eye morphogenesis GO:0048592 144 0.010
regulation of lyase activity GO:0051339 12 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
nucleic acid metabolic process GO:0090304 244 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
positive regulation of leukocyte chemotaxis GO:0002690 1 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
fertilization GO:0009566 3 0.010
myotube differentiation GO:0014902 45 0.010
rna localization GO:0006403 4 0.010
spermatid development GO:0007286 2 0.010
programmed cell death GO:0012501 119 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
cell substrate junction assembly GO:0007044 2 0.010
lymph vessel morphogenesis GO:0036303 25 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
regulation of chromosome segregation GO:0051983 1 0.010
developmental growth GO:0048589 166 0.010
cellular response to radiation GO:0071478 4 0.010
hormone secretion GO:0046879 2 0.010

LOC566040 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.065
nervous system disease DOID:863 0 0.020
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
myopathy DOID:423 0 0.018
muscle tissue disease DOID:66 0 0.018
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010