Danio rerio

0 known processes

myoc

myocilin

(Aliases: zgc:136645,MGC136645)

myoc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal muscle organ development GO:0060538 78 0.262
larval development GO:0002164 2 0.171
cell surface receptor signaling pathway GO:0007166 325 0.145
single organism transport GO:0044765 206 0.123
muscle cell development GO:0055001 115 0.117
immune system process GO:0002376 241 0.113
response to chemical GO:0042221 320 0.110
muscle organ development GO:0007517 101 0.104
establishment of localization GO:0051234 244 0.101
regulation of signaling GO:0023051 235 0.094
regulation of cell communication GO:0010646 232 0.094
muscle fiber development GO:0048747 52 0.092
signal transduction GO:0007165 455 0.087
positive regulation of biological process GO:0048518 253 0.086
regulation of blood pressure GO:0008217 1 0.081
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.078
transport GO:0006810 220 0.074
digestive tract development GO:0048565 265 0.073
biosynthetic process GO:0009058 294 0.072
response to external stimulus GO:0009605 264 0.071
embryonic organ development GO:0048568 381 0.070
organic cyclic compound biosynthetic process GO:1901362 223 0.069
cellular aromatic compound metabolic process GO:0006725 295 0.067
system process GO:0003008 185 0.065
positive regulation of transport GO:0051050 2 0.061
regulation of metabolic process GO:0019222 359 0.060
muscle cell differentiation GO:0042692 139 0.059
adult behavior GO:0030534 2 0.058
cellular response to xenobiotic stimulus GO:0071466 35 0.057
muscle structure development GO:0061061 196 0.056
response to corticosteroid GO:0031960 1 0.056
response to organic substance GO:0010033 153 0.055
regulation of signal transduction GO:0009966 225 0.055
response to stress GO:0006950 263 0.054
cell projection organization GO:0030030 284 0.053
regulation of multicellular organism growth GO:0040014 4 0.052
embryo development ending in birth or egg hatching GO:0009792 271 0.051
embryonic organ morphogenesis GO:0048562 274 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
aging GO:0007568 2 0.051
response to nutrient GO:0007584 3 0.050
ion transport GO:0006811 114 0.049
transmembrane transport GO:0055085 120 0.049
regulation of cytokine production GO:0001817 3 0.048
organonitrogen compound metabolic process GO:1901564 74 0.048
regulation of response to stimulus GO:0048583 269 0.048
cellular macromolecule metabolic process GO:0044260 391 0.048
positive regulation of cytokine production GO:0001819 2 0.047
heterocycle metabolic process GO:0046483 290 0.047
regulation of cellular biosynthetic process GO:0031326 245 0.046
maintenance of location GO:0051235 4 0.046
response to glucocorticoid GO:0051384 1 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.044
organic cyclic compound metabolic process GO:1901360 301 0.044
cellular response to external stimulus GO:0071496 2 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.043
extrinsic apoptotic signaling pathway GO:0097191 3 0.043
response to xenobiotic stimulus GO:0009410 45 0.042
regulation of cellular metabolic process GO:0031323 320 0.042
extracellular matrix organization GO:0030198 27 0.042
head development GO:0060322 303 0.041
gene expression GO:0010467 252 0.041
striated muscle cell development GO:0055002 108 0.041
regulation of endothelial cell proliferation GO:0001936 1 0.041
cellular biosynthetic process GO:0044249 286 0.040
small molecule metabolic process GO:0044281 77 0.040
morphogenesis of an epithelium GO:0002009 333 0.039
cellular component assembly GO:0022607 170 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
skeletal muscle tissue development GO:0007519 67 0.038
response to biotic stimulus GO:0009607 97 0.038
single organism localization GO:1902578 225 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
protein localization to nucleus GO:0034504 3 0.037
regulation of systemic arterial blood pressure GO:0003073 1 0.037
positive regulation of catabolic process GO:0009896 4 0.036
response to external biotic stimulus GO:0043207 97 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
extracellular structure organization GO:0043062 27 0.035
notch signaling pathway GO:0007219 35 0.035
response to vitamin GO:0033273 3 0.035
response to monosaccharide GO:0034284 3 0.033
renal system process involved in regulation of blood volume GO:0001977 1 0.033
oxoacid metabolic process GO:0043436 31 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
digestive system development GO:0055123 289 0.032
nucleic acid templated transcription GO:0097659 181 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
lipid storage GO:0019915 1 0.032
blood circulation GO:0008015 87 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.031
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.031
response to other organism GO:0051707 97 0.031
cellular response to radiation GO:0071478 4 0.031
atp catabolic process GO:0006200 4 0.031
carboxylic acid metabolic process GO:0019752 22 0.031
regulation of transcription dna templated GO:0006355 213 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
brain development GO:0007420 293 0.030
ion transmembrane transport GO:0034220 91 0.030
endocrine process GO:0050886 2 0.030
muscle tissue development GO:0060537 110 0.030
response to abiotic stimulus GO:0009628 122 0.030
regulation of primary metabolic process GO:0080090 311 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
regulation of multicellular organismal process GO:0051239 277 0.028
regulation of gene expression GO:0010468 265 0.028
rna metabolic process GO:0016070 219 0.028
renal filtration GO:0097205 10 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
response to glucose GO:0009749 3 0.028
amine metabolic process GO:0009308 2 0.028
specification of symmetry GO:0009799 204 0.028
response to carbohydrate GO:0009743 3 0.028
cellular amino acid metabolic process GO:0006520 7 0.027
heart development GO:0007507 313 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
cellular component movement GO:0006928 335 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
cellular ketone metabolic process GO:0042180 11 0.027
regulation of protein complex assembly GO:0043254 3 0.027
macromolecule biosynthetic process GO:0009059 227 0.026
response to drug GO:0042493 3 0.026
embryonic heart tube morphogenesis GO:0003143 108 0.026
cell morphogenesis GO:0000902 289 0.026
cation transmembrane transport GO:0098655 65 0.026
neuron differentiation GO:0030182 353 0.026
fatty acid biosynthetic process GO:0006633 4 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
heterocycle biosynthetic process GO:0018130 215 0.025
nuclear transport GO:0051169 4 0.025
regulation of cell projection assembly GO:0060491 4 0.025
negative regulation of cellular process GO:0048523 283 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
phagocytosis GO:0006909 3 0.025
cellular component biogenesis GO:0044085 178 0.025
tube morphogenesis GO:0035239 349 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
cellular amine metabolic process GO:0044106 2 0.025
striated muscle cell differentiation GO:0051146 129 0.024
leukocyte proliferation GO:0070661 1 0.024
protein metabolic process GO:0019538 183 0.024
protein polymerization GO:0051258 4 0.024
regulation of tube size GO:0035150 2 0.024
multicellular organism growth GO:0035264 4 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.023
regulation of developmental process GO:0050793 247 0.023
regulation of cell shape GO:0008360 1 0.023
response to transition metal nanoparticle GO:1990267 28 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
sleep GO:0030431 1 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
multicellular organismal response to stress GO:0033555 2 0.022
regulation of blood vessel size GO:0050880 2 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
nucleic acid metabolic process GO:0090304 244 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
stem cell division GO:0017145 1 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
regulation of reproductive process GO:2000241 4 0.021
immune system development GO:0002520 191 0.021
response to organic cyclic compound GO:0014070 51 0.021
positive regulation of epithelial cell proliferation GO:0050679 1 0.021
regulation of biological quality GO:0065008 263 0.021
regulation of inflammatory response GO:0050727 2 0.020
regulation of biosynthetic process GO:0009889 250 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
notochord development GO:0030903 54 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
negative regulation of biological process GO:0048519 304 0.020
striated muscle tissue development GO:0014706 110 0.020
nitric oxide metabolic process GO:0046209 2 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
regulation of establishment of protein localization GO:0070201 4 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
vasculature development GO:0001944 278 0.019
positive regulation of cell cycle GO:0045787 3 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
regulation of wound healing GO:0061041 2 0.019
response to wounding GO:0009611 116 0.019
tissue remodeling GO:0048771 4 0.019
protein import GO:0017038 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of cell activation GO:0050865 1 0.019
cellular response to nutrient levels GO:0031669 2 0.018
organic substance biosynthetic process GO:1901576 289 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
renal system process GO:0003014 14 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
regulation of circadian rhythm GO:0042752 4 0.018
rna biosynthetic process GO:0032774 181 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
cellular component disassembly GO:0022411 1 0.018
stem cell proliferation GO:0072089 4 0.018
single organism biosynthetic process GO:0044711 71 0.017
g protein coupled receptor signaling pathway GO:0007186 74 0.017
carbohydrate biosynthetic process GO:0016051 1 0.017
hemopoiesis GO:0030097 183 0.017
astrocyte differentiation GO:0048708 1 0.017
meiotic nuclear division GO:0007126 4 0.017
response to hexose GO:0009746 3 0.017
eye development GO:0001654 277 0.017
cell death GO:0008219 121 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
death GO:0016265 121 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
sensory organ morphogenesis GO:0090596 200 0.017
regulation of system process GO:0044057 40 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of rna metabolic process GO:0051252 224 0.017
response to virus GO:0009615 21 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
response to ketone GO:1901654 1 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
single organism metabolic process GO:0044710 217 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
multi organism process GO:0051704 134 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
regulation of muscle contraction GO:0006937 3 0.016
heart looping GO:0001947 94 0.016
negative regulation of defense response GO:0031348 2 0.016
bmp signaling pathway GO:0030509 52 0.016
water homeostasis GO:0030104 4 0.016
generation of neurons GO:0048699 385 0.016
peptide metabolic process GO:0006518 1 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
locomotion GO:0040011 313 0.015
post embryonic organ development GO:0048569 4 0.015
organic substance transport GO:0071702 58 0.015
cation transport GO:0006812 81 0.015
gtp catabolic process GO:0006184 2 0.015
metal ion transport GO:0030001 58 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
positive regulation of gene expression GO:0010628 71 0.015
regulation of metal ion transport GO:0010959 4 0.015
mitochondrion organization GO:0007005 4 0.015
cellular localization GO:0051641 97 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
positive regulation of neuron death GO:1901216 1 0.015
endocrine hormone secretion GO:0060986 2 0.015
camera type eye development GO:0043010 222 0.015
hormone transport GO:0009914 2 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
circulatory system process GO:0003013 87 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
behavior GO:0007610 74 0.014
cell part morphogenesis GO:0032990 246 0.014
sensory organ development GO:0007423 393 0.014
protein stabilization GO:0050821 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
protein secretion GO:0009306 1 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
neurological system process GO:0050877 62 0.014
regulation of protein polymerization GO:0032271 2 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
establishment of localization in cell GO:0051649 77 0.014
cellular response to oxygen levels GO:0071453 1 0.014
skeletal system development GO:0001501 181 0.014
collagen fibril organization GO:0030199 1 0.014
transcription dna templated GO:0006351 181 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
cellular amide metabolic process GO:0043603 4 0.014
oocyte maturation GO:0001556 4 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
blood vessel morphogenesis GO:0048514 216 0.013
nitric oxide biosynthetic process GO:0006809 2 0.013
hormone secretion GO:0046879 2 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
nuclear import GO:0051170 3 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
response to bacterium GO:0009617 58 0.013
blood vessel development GO:0001568 246 0.013
response to radiation GO:0009314 51 0.013
regulation of protein catabolic process GO:0042176 1 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
positive regulation of leukocyte chemotaxis GO:0002690 1 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
somatic muscle development GO:0007525 4 0.013
regulation of organ growth GO:0046620 3 0.013
programmed cell death GO:0012501 119 0.013
cellular response to organic substance GO:0071310 105 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
actin filament based movement GO:0030048 1 0.013
regulation of protein transport GO:0051223 3 0.013
regulation of filopodium assembly GO:0051489 2 0.012
carbohydrate homeostasis GO:0033500 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
homeostatic process GO:0042592 142 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
regulation of cellular component movement GO:0051270 55 0.012
negative regulation of cytokine production GO:0001818 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
nuclear export GO:0051168 1 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
cell migration GO:0016477 237 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regulation of membrane potential GO:0042391 23 0.012
positive regulation of cell activation GO:0050867 1 0.012
cell substrate adhesion GO:0031589 4 0.011
stem cell maintenance GO:0019827 4 0.011
response to topologically incorrect protein GO:0035966 2 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
sensory perception of pain GO:0019233 1 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
single organism nuclear import GO:1902593 3 0.011
positive regulation of blood circulation GO:1903524 2 0.011
positive regulation of secretion GO:0051047 1 0.011
eye morphogenesis GO:0048592 144 0.011
glomerular filtration GO:0003094 6 0.011
regulation of transporter activity GO:0032409 2 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
determination of bilateral symmetry GO:0009855 204 0.011
response to lipid GO:0033993 60 0.011
neuron development GO:0048666 262 0.011
apoptotic process GO:0006915 116 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
cellular protein catabolic process GO:0044257 4 0.011
cellular response to stress GO:0033554 62 0.011
angiogenesis GO:0001525 158 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
negative regulation of metabolic process GO:0009892 86 0.010
intracellular signal transduction GO:0035556 85 0.010
skeletal system morphogenesis GO:0048705 102 0.010
mononuclear cell proliferation GO:0032943 1 0.010
positive regulation of cell communication GO:0010647 56 0.010
protein heterooligomerization GO:0051291 1 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
response to endogenous stimulus GO:0009719 83 0.010
positive regulation of metabolic process GO:0009893 108 0.010
cellular response to hypoxia GO:0071456 1 0.010
membrane invagination GO:0010324 1 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
protein homooligomerization GO:0051260 3 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010

myoc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
musculoskeletal system disease DOID:17 0 0.030
bone disease DOID:0080001 0 0.023
connective tissue disease DOID:65 0 0.023
muscular disease DOID:0080000 0 0.021
muscle tissue disease DOID:66 0 0.021
bone development disease DOID:0080006 0 0.015
nervous system disease DOID:863 0 0.015
osteochondrodysplasia DOID:2256 0 0.011
charcot marie tooth disease type 4 DOID:0050541 0 0.011
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011