Danio rerio

16 known processes

pggt1b

protein geranylgeranyltransferase type I, beta subunit

(Aliases: MGC114070,zgc:114070)

pggt1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
somite development GO:0061053 96 0.218
dorsal ventral pattern formation GO:0009953 125 0.136
regulation of multicellular organism growth GO:0040014 4 0.128
regulation of rna metabolic process GO:0051252 224 0.114
regulation of stem cell differentiation GO:2000736 4 0.089
regulation of multicellular organismal process GO:0051239 277 0.084
regulation of embryonic development GO:0045995 47 0.083
sensory system development GO:0048880 76 0.081
gastrulation GO:0007369 208 0.080
response to stress GO:0006950 263 0.078
embryonic heart tube development GO:0035050 133 0.077
Fly
regionalization GO:0003002 274 0.076
pancreas development GO:0031016 84 0.075
phagocytosis GO:0006909 3 0.074
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.072
regulation of developmental process GO:0050793 247 0.071
optic placode formation involved in camera type eye formation GO:0046619 3 0.071
regulation of oocyte development GO:0060281 3 0.068
guanosine containing compound catabolic process GO:1901069 2 0.066
wnt signaling pathway GO:0016055 80 0.066
nucleobase containing compound metabolic process GO:0006139 274 0.063
cell migration GO:0016477 237 0.063
embryonic cranial skeleton morphogenesis GO:0048701 90 0.062
convergent extension GO:0060026 118 0.060
endocrine system development GO:0035270 65 0.059
specification of symmetry GO:0009799 204 0.055
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
immune system process GO:0002376 241 0.054
blood vessel development GO:0001568 246 0.054
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.052
heterocycle biosynthetic process GO:0018130 215 0.049
morphogenesis of an epithelium GO:0002009 333 0.048
nucleic acid templated transcription GO:0097659 181 0.048
somitogenesis GO:0001756 87 0.047
determination of left right symmetry GO:0007368 179 0.047
fertilization GO:0009566 3 0.047
optic placode formation GO:0001743 4 0.047
rna biosynthetic process GO:0032774 181 0.046
regulation of reproductive process GO:2000241 4 0.045
positive regulation of embryonic development GO:0040019 3 0.044
positive regulation of biological process GO:0048518 253 0.044
Fly
negative regulation of mitosis GO:0045839 3 0.043
nuclear transport GO:0051169 4 0.043
determination of bilateral symmetry GO:0009855 204 0.043
liver development GO:0001889 96 0.043
nucleocytoplasmic transport GO:0006913 4 0.043
lateral line development GO:0048882 66 0.042
regulation of epithelial cell proliferation GO:0050678 3 0.042
stem cell proliferation GO:0072089 4 0.042
gtp catabolic process GO:0006184 2 0.041
oocyte maturation GO:0001556 4 0.040
ameboidal type cell migration GO:0001667 143 0.039
digestive tract development GO:0048565 265 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
digestive tract morphogenesis GO:0048546 231 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.039
aging GO:0007568 2 0.038
neuroblast proliferation GO:0007405 2 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
epithelial tube morphogenesis GO:0060562 148 0.037
positive regulation of gtp catabolic process GO:0033126 1 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
positive regulation of gtpase activity GO:0043547 1 0.036
positive regulation of muscle cell differentiation GO:0051149 1 0.036
central nervous system development GO:0007417 387 0.035
regulation of gtp catabolic process GO:0033124 2 0.035
embryonic organ morphogenesis GO:0048562 274 0.035
positive regulation of cell fate commitment GO:0010455 1 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.034
connective tissue development GO:0061448 99 0.034
negative regulation of mapk cascade GO:0043409 4 0.034
gtp metabolic process GO:0046039 4 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.034
organelle organization GO:0006996 227 0.033
digestive system development GO:0055123 289 0.033
heart looping GO:0001947 94 0.033
cellular response to nutrient levels GO:0031669 2 0.033
lateral inhibition GO:0046331 1 0.033
lateral line system development GO:0048925 76 0.033
regulation of metabolic process GO:0019222 359 0.032
Fly
positive regulation of nucleoside metabolic process GO:0045979 1 0.031
multicellular organism growth GO:0035264 4 0.031
positive regulation of cellular process GO:0048522 201 0.031
Fly
cell morphogenesis GO:0000902 289 0.031
regulation of heart morphogenesis GO:2000826 17 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
hemopoiesis GO:0030097 183 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.031
regulation of gene expression GO:0010468 265 0.031
compound eye development GO:0048749 2 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.030
heart development GO:0007507 313 0.030
Fly
guanosine containing compound metabolic process GO:1901068 4 0.030
single fertilization GO:0007338 3 0.030
enzyme linked receptor protein signaling pathway GO:0007167 106 0.029
single organism metabolic process GO:0044710 217 0.029
Fly
cell motility GO:0048870 244 0.029
endocrine pancreas development GO:0031018 27 0.029
embryonic eye morphogenesis GO:0048048 30 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.028
cell growth GO:0016049 57 0.028
cartilage development GO:0051216 96 0.028
cell projection organization GO:0030030 284 0.028
gland development GO:0048732 143 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
larval development GO:0002164 2 0.028
cognition GO:0050890 1 0.028
regulation of nucleoside metabolic process GO:0009118 2 0.028
auditory receptor cell fate commitment GO:0009912 4 0.028
positive regulation of nucleotide catabolic process GO:0030813 1 0.027
regulation of cellular component organization GO:0051128 86 0.027
neurotransmitter transport GO:0006836 2 0.027
immune system development GO:0002520 191 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
pronephros development GO:0048793 69 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
nucleic acid metabolic process GO:0090304 244 0.026
angiogenesis GO:0001525 158 0.026
embryonic neurocranium morphogenesis GO:0048702 15 0.026
cell fate commitment GO:0045165 99 0.025
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.025
negative regulation of nuclear division GO:0051784 3 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
mesodermal cell differentiation GO:0048333 21 0.025
regulation of nucleotide catabolic process GO:0030811 2 0.025
protein import GO:0017038 3 0.025
heterocycle metabolic process GO:0046483 290 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
Fly
cellular response to external stimulus GO:0071496 2 0.024
skeletal system development GO:0001501 181 0.024
myeloid cell differentiation GO:0030099 86 0.024
regulation of organ morphogenesis GO:2000027 35 0.024
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.024
regulation of protein targeting GO:1903533 2 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
thrombocyte differentiation GO:0002574 4 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
anterior posterior pattern specification GO:0009952 152 0.023
regulation of gtpase activity GO:0043087 2 0.023
sensory epithelium regeneration GO:0070654 14 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
spinal cord anterior posterior patterning GO:0021512 1 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
negative regulation of map kinase activity GO:0043407 2 0.023
determination of heart left right asymmetry GO:0061371 117 0.023
regulation of meiotic cell cycle GO:0051445 1 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
developmental growth GO:0048589 166 0.022
epithelium regeneration GO:1990399 14 0.022
mesoderm development GO:0007498 88 0.022
developmental cell growth GO:0048588 52 0.022
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.022
regulation of signal transduction GO:0009966 225 0.022
Fly
pharyngeal muscle development GO:0043282 4 0.022
locomotion GO:0040011 313 0.021
regulation of mesenchymal cell proliferation GO:0010464 1 0.021
kidney development GO:0001822 92 0.021
convergent extension involved in gastrulation GO:0060027 71 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
cellular localization GO:0051641 97 0.021
cardiac cell fate commitment GO:0060911 1 0.020
forebrain development GO:0030900 96 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
mediolateral intercalation GO:0060031 3 0.020
heart jogging GO:0003146 40 0.020
regulation of response to stimulus GO:0048583 269 0.020
Fly
thalamus development GO:0021794 6 0.020
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of protein transport GO:0051223 3 0.019
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
stem cell maintenance GO:0019827 4 0.019
exocytosis GO:0006887 1 0.018
vasculature development GO:0001944 278 0.018
cellular ketone metabolic process GO:0042180 11 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
regulation of biological quality GO:0065008 263 0.018
neuromast development GO:0048884 46 0.018
epithelial cell morphogenesis GO:0003382 2 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.018
heart morphogenesis GO:0003007 156 0.018
canonical wnt signaling pathway GO:0060070 48 0.018
organelle localization GO:0051640 49 0.018
hepaticobiliary system development GO:0061008 98 0.018
positive regulation of cell cycle GO:0045787 3 0.018
establishment of localization GO:0051234 244 0.018
regulation of primary metabolic process GO:0080090 311 0.017
neural plate pattern specification GO:0060896 12 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
formation of primary germ layer GO:0001704 62 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
cell substrate junction assembly GO:0007044 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
negative regulation of kinase activity GO:0033673 4 0.017
negative regulation of developmental process GO:0051093 65 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
protein k63 linked ubiquitination GO:0070534 2 0.016
renal system development GO:0072001 94 0.016
maintenance of location GO:0051235 4 0.016
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.016
muscle structure development GO:0061061 196 0.016
localization of cell GO:0051674 244 0.016
triglyceride homeostasis GO:0070328 2 0.016
determination of dorsal ventral asymmetry GO:0048262 34 0.016
eye development GO:0001654 277 0.016
protein targeting to nucleus GO:0044744 3 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
chemosensory behavior GO:0007635 1 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.016
release of sequestered calcium ion into cytosol GO:0051209 3 0.016
neurotransmitter secretion GO:0007269 2 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
melanosome localization GO:0032400 21 0.016
epithelial cell differentiation GO:0030855 116 0.015
cell projection morphogenesis GO:0048858 244 0.015
regulation of cell differentiation GO:0045595 142 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
single organism organelle organization GO:1902589 199 0.015
axis specification GO:0009798 43 0.015
positive regulation of transport GO:0051050 2 0.015
embryonic organ development GO:0048568 381 0.015
Fly
homeostatic process GO:0042592 142 0.015
protein secretion GO:0009306 1 0.015
endoderm development GO:0007492 49 0.015
behavior GO:0007610 74 0.015
negative regulation of wnt signaling pathway GO:0030178 30 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
small molecule metabolic process GO:0044281 77 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
cellular protein catabolic process GO:0044257 4 0.015
cell part morphogenesis GO:0032990 246 0.014
hepatocyte proliferation GO:0072574 2 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
nephron epithelium morphogenesis GO:0072088 1 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
mesenchymal cell proliferation GO:0010463 1 0.014
rna stabilization GO:0043489 4 0.014
ectodermal placode development GO:0071696 37 0.014
growth GO:0040007 174 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
cell cycle g2 m phase transition GO:0044839 4 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
segmentation GO:0035282 97 0.014
tube formation GO:0035148 25 0.014
regulation of epithelial to mesenchymal transition GO:0010717 3 0.014
positive regulation of ras gtpase activity GO:0032320 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
positive regulation of catabolic process GO:0009896 4 0.014
myeloid cell development GO:0061515 32 0.014
endosomal transport GO:0016197 2 0.014
regulation of cell shape GO:0008360 1 0.014
hormone biosynthetic process GO:0042446 3 0.014
negative regulation of reproductive process GO:2000242 3 0.014
membrane invagination GO:0010324 1 0.013
epiboly GO:0090504 41 0.013
spermatid development GO:0007286 2 0.013
mesodermal cell migration GO:0008078 12 0.013
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
Fly
regulation of sequestering of calcium ion GO:0051282 4 0.013
embryonic skeletal system development GO:0048706 97 0.013
glucose homeostasis GO:0042593 1 0.013
myotome development GO:0061055 1 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
organic acid catabolic process GO:0016054 3 0.013
response to chemical GO:0042221 320 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
protein polyubiquitination GO:0000209 4 0.013
sensory organ development GO:0007423 393 0.013
establishment of localization in cell GO:0051649 77 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
regulation of anterior head development GO:2000742 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
fatty acid transport GO:0015908 1 0.012
gene expression GO:0010467 252 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
intracellular signal transduction GO:0035556 85 0.012
Fly
neural crest cell migration GO:0001755 42 0.012
positive regulation of oocyte development GO:0060282 1 0.012
regulation of inner ear receptor cell differentiation GO:2000980 1 0.012
intracellular transport GO:0046907 32 0.012
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.012
lipid storage GO:0019915 1 0.012
transcription dna templated GO:0006351 181 0.011
oocyte development GO:0048599 14 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
cellular response to starvation GO:0009267 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
camera type eye morphogenesis GO:0048593 108 0.011
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.011
signal transduction GO:0007165 455 0.011
Fly
organonitrogen compound metabolic process GO:1901564 74 0.011
regulation of bmp signaling pathway GO:0030510 39 0.011
phagocytosis engulfment GO:0006911 1 0.011
brain development GO:0007420 293 0.011
single organism transport GO:0044765 206 0.011
negative regulation of leukocyte differentiation GO:1902106 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
amine metabolic process GO:0009308 2 0.011
single organism cellular localization GO:1902580 46 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
rna metabolic process GO:0016070 219 0.011
negative regulation of jnk cascade GO:0046329 1 0.011
cell fate specification GO:0001708 68 0.010
regulation of cell maturation GO:1903429 1 0.010
blood vessel morphogenesis GO:0048514 216 0.010
renal tubule morphogenesis GO:0061333 1 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.010
negative regulation of histone modification GO:0031057 1 0.010
protein import into nucleus GO:0006606 3 0.010
developmental programmed cell death GO:0010623 4 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
oxoacid metabolic process GO:0043436 31 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
cellular component maintenance GO:0043954 3 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
negative regulation of signaling GO:0023057 96 0.010
urogenital system development GO:0001655 97 0.010
leukocyte differentiation GO:0002521 25 0.010
diencephalon development GO:0021536 58 0.010

pggt1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
bone development disease DOID:0080006 0 0.017
bone disease DOID:0080001 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.010