Danio rerio

15 known processes

pde6d

phosphodiesterase 6D, cGMP-specific, rod, delta

(Aliases: zgc:92605)

pde6d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.159
positive regulation of transport GO:0051050 2 0.050
aging GO:0007568 2 0.048
multicellular organism growth GO:0035264 4 0.044
maintenance of location GO:0051235 4 0.040
cognition GO:0050890 1 0.040
signal transduction GO:0007165 455 0.039
regulation of cell shape GO:0008360 1 0.039
nucleocytoplasmic transport GO:0006913 4 0.038
regulation of nucleoside metabolic process GO:0009118 2 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
single organism localization GO:1902578 225 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
regulation of protein transport GO:0051223 3 0.033
gtp metabolic process GO:0046039 4 0.033
organic cyclic compound metabolic process GO:1901360 301 0.032
guanosine containing compound catabolic process GO:1901069 2 0.032
meiotic nuclear division GO:0007126 4 0.032
regulation of establishment of protein localization GO:0070201 4 0.031
single organism nuclear import GO:1902593 3 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
regulation of biological quality GO:0065008 263 0.030
cellular component disassembly GO:0022411 1 0.030
transport GO:0006810 220 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
establishment of localization GO:0051234 244 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
positive regulation of catabolic process GO:0009896 4 0.029
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.028
regulation of binding GO:0051098 3 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
lipid storage GO:0019915 1 0.028
single organism transport GO:0044765 206 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
guanosine containing compound metabolic process GO:1901068 4 0.028
phagocytosis GO:0006909 3 0.028
stem cell proliferation GO:0072089 4 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
response to chemical GO:0042221 320 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
protein localization to plasma membrane GO:0072659 1 0.027
cellular component morphogenesis GO:0032989 336 0.026
gtp catabolic process GO:0006184 2 0.026
nuclear transport GO:0051169 4 0.026
generation of neurons GO:0048699 385 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
regulation of gtp catabolic process GO:0033124 2 0.026
protein polymerization GO:0051258 4 0.026
cell morphogenesis GO:0000902 289 0.026
regulation of cytoplasmic transport GO:1903649 4 0.025
rna localization GO:0006403 4 0.025
mitochondrion organization GO:0007005 4 0.025
protein targeting to nucleus GO:0044744 3 0.025
protein import into nucleus GO:0006606 3 0.025
regulation of synapse organization GO:0050807 3 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
regulation of signaling GO:0023051 235 0.023
cell part morphogenesis GO:0032990 246 0.023
digestive tract development GO:0048565 265 0.023
response to drug GO:0042493 3 0.023
nuclear import GO:0051170 3 0.023
locomotor rhythm GO:0045475 3 0.023
positive regulation of biological process GO:0048518 253 0.023
regulation of cytokine production GO:0001817 3 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
heterocycle metabolic process GO:0046483 290 0.022
phagocytosis engulfment GO:0006911 1 0.022
cellular component movement GO:0006928 335 0.022
membrane invagination GO:0010324 1 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
cell projection morphogenesis GO:0048858 244 0.021
organelle organization GO:0006996 227 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
central nervous system development GO:0007417 387 0.021
positive regulation of gtp catabolic process GO:0033126 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
protein import GO:0017038 3 0.021
protein localization to nucleus GO:0034504 3 0.021
regulation of cell activation GO:0050865 1 0.020
chemosensory behavior GO:0007635 1 0.020
regulation of reproductive process GO:2000241 4 0.020
biosynthetic process GO:0009058 294 0.020
system process GO:0003008 185 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
regulation of synapse assembly GO:0051963 3 0.020
single organism organelle organization GO:1902589 199 0.020
positive regulation of cell cycle GO:0045787 3 0.020
protein complex disassembly GO:0043241 1 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
gastrulation GO:0007369 208 0.019
cell projection organization GO:0030030 284 0.019
regulation of gtpase activity GO:0043087 2 0.019
positive regulation of gtpase activity GO:0043547 1 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
endosomal transport GO:0016197 2 0.019
autophagy GO:0006914 4 0.019
leukocyte proliferation GO:0070661 1 0.018
regionalization GO:0003002 274 0.018
mononuclear cell proliferation GO:0032943 1 0.018
cytoplasm organization GO:0007028 4 0.018
vasculature development GO:0001944 278 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
locomotion GO:0040011 313 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
regulation of rho protein signal transduction GO:0035023 2 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
regulation of developmental process GO:0050793 247 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
regulation of primary metabolic process GO:0080090 311 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of protein targeting GO:1903533 2 0.018
regulation of gene expression GO:0010468 265 0.018
actin filament polymerization GO:0030041 2 0.018
macromolecular complex disassembly GO:0032984 1 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
small molecule metabolic process GO:0044281 77 0.017
immune system development GO:0002520 191 0.017
tube morphogenesis GO:0035239 349 0.017
phosphorus metabolic process GO:0006793 109 0.017
protein metabolic process GO:0019538 183 0.017
regulation of protein polymerization GO:0032271 2 0.017
spermatid differentiation GO:0048515 2 0.017
gene expression GO:0010467 252 0.017
digestive system development GO:0055123 289 0.017
female sex differentiation GO:0046660 4 0.017
nucleic acid templated transcription GO:0097659 181 0.017
meiotic cell cycle process GO:1903046 3 0.017
neuroblast proliferation GO:0007405 2 0.017
female meiotic division GO:0007143 2 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
rna transport GO:0050658 2 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
lymphocyte proliferation GO:0046651 1 0.017
amine metabolic process GO:0009308 2 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
nucleic acid transport GO:0050657 2 0.016
regulation of muscle contraction GO:0006937 3 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
single organism metabolic process GO:0044710 217 0.016
synaptic vesicle localization GO:0097479 1 0.016
embryonic organ development GO:0048568 381 0.016
cellular localization GO:0051641 97 0.016
cellular response to external stimulus GO:0071496 2 0.016
head development GO:0060322 303 0.016
protein acetylation GO:0006473 2 0.016
cell matrix adhesion GO:0007160 4 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
response to external stimulus GO:0009605 264 0.016
regulation of mrna processing GO:0050684 3 0.016
positive regulation of protein polymerization GO:0032273 2 0.016
organic substance biosynthetic process GO:1901576 289 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
response to uv GO:0009411 3 0.016
cellular response to nutrient levels GO:0031669 2 0.016
immune system process GO:0002376 241 0.015
neurotransmitter transport GO:0006836 2 0.015
cellular amine metabolic process GO:0044106 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
brain development GO:0007420 293 0.015
cell substrate adhesion GO:0031589 4 0.015
positive regulation of secretion GO:0051047 1 0.015
response to carbohydrate GO:0009743 3 0.015
stem cell maintenance GO:0019827 4 0.015
spermatid development GO:0007286 2 0.015
heart development GO:0007507 313 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
regulation of signal transduction GO:0009966 225 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
compound eye development GO:0048749 2 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of neurotransmitter transport GO:0051588 1 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
digestive tract morphogenesis GO:0048546 231 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of response to stimulus GO:0048583 269 0.015
nuclear export GO:0051168 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.015
multi organism process GO:0051704 134 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
dna templated transcription elongation GO:0006354 3 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
negative regulation of kinase activity GO:0033673 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
chordate embryonic development GO:0043009 271 0.014
apical junction assembly GO:0043297 1 0.014
neuron development GO:0048666 262 0.014
cellular ketone metabolic process GO:0042180 11 0.014
organic acid metabolic process GO:0006082 31 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
growth GO:0040007 174 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
rna metabolic process GO:0016070 219 0.014
b cell activation GO:0042113 2 0.014
response to stress GO:0006950 263 0.014
female gonad development GO:0008585 4 0.014
golgi vesicle transport GO:0048193 3 0.014
sleep GO:0030431 1 0.014
determination of bilateral symmetry GO:0009855 204 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
protein secretion GO:0009306 1 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
eye development GO:0001654 277 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
tissue remodeling GO:0048771 4 0.014
neuron differentiation GO:0030182 353 0.014
atp catabolic process GO:0006200 4 0.014
cellular response to starvation GO:0009267 1 0.013
protein acylation GO:0043543 3 0.013
oocyte maturation GO:0001556 4 0.013
regulation of protein catabolic process GO:0042176 1 0.013
peptide transport GO:0015833 1 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
positive regulation of cellular process GO:0048522 201 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
camera type eye development GO:0043010 222 0.013
regulation of metabolic process GO:0019222 359 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
blood vessel development GO:0001568 246 0.013
stem cell division GO:0017145 1 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
regulation of circadian rhythm GO:0042752 4 0.013
rna export from nucleus GO:0006405 1 0.013
localization of cell GO:0051674 244 0.013
regulation of metal ion transport GO:0010959 4 0.013
cell motility GO:0048870 244 0.013
response to organic substance GO:0010033 153 0.013
synaptic vesicle endocytosis GO:0048488 1 0.013
regulation of blood pressure GO:0008217 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
negative regulation of catabolic process GO:0009895 3 0.013
regulation of rna metabolic process GO:0051252 224 0.013
response to monosaccharide GO:0034284 3 0.013
muscle structure development GO:0061061 196 0.012
cellular biosynthetic process GO:0044249 286 0.012
cytokinesis GO:0000910 3 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
lateral line system development GO:0048925 76 0.012
epithelial cell differentiation GO:0030855 116 0.012
pole plasm assembly GO:0007315 4 0.012
regulation of ph GO:0006885 3 0.012
protein dephosphorylation GO:0006470 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
zymogen activation GO:0031638 3 0.012
response to corticosteroid GO:0031960 1 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of cytokine production GO:0001819 2 0.012
cellular protein metabolic process GO:0044267 129 0.012
smooth muscle contraction GO:0006939 2 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
negative regulation of biological process GO:0048519 304 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
hormone transport GO:0009914 2 0.012
sensory system development GO:0048880 76 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
establishment of rna localization GO:0051236 3 0.012
posterior lateral line system development GO:0048915 46 0.012
transcription dna templated GO:0006351 181 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
renal tubule morphogenesis GO:0061333 1 0.012
meiotic chromosome segregation GO:0045132 3 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
intracellular mrna localization GO:0008298 1 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
cell migration GO:0016477 237 0.012
response to hexose GO:0009746 3 0.012
exocytosis GO:0006887 1 0.011
nucleic acid metabolic process GO:0090304 244 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cytoskeleton organization GO:0007010 96 0.011
cell aging GO:0007569 2 0.011
macromolecule modification GO:0043412 111 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
response to abiotic stimulus GO:0009628 122 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
sequestering of calcium ion GO:0051208 3 0.011
positive regulation of translation GO:0045727 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
cellular component assembly GO:0022607 170 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
regulation of blood vessel size GO:0050880 2 0.011
hemopoiesis GO:0030097 183 0.011
oxoacid metabolic process GO:0043436 31 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
regulation of tube size GO:0035150 2 0.011
synaptic vesicle recycling GO:0036465 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
membrane fusion GO:0061025 2 0.011
response to glucose GO:0009749 3 0.011
single fertilization GO:0007338 3 0.011
negative regulation of cellular process GO:0048523 283 0.011
antimicrobial humoral response GO:0019730 2 0.011
hormone secretion GO:0046879 2 0.011
astrocyte differentiation GO:0048708 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cilium assembly GO:0042384 58 0.011
nephron morphogenesis GO:0072028 2 0.011
cellular response to radiation GO:0071478 4 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
homeostatic process GO:0042592 142 0.011
cellular response to organic substance GO:0071310 105 0.011
cellular response to oxygen levels GO:0071453 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
fertilization GO:0009566 3 0.011
nucleobase containing compound transport GO:0015931 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
neurological system process GO:0050877 62 0.011
cell substrate junction assembly GO:0007044 2 0.011
intracellular signal transduction GO:0035556 85 0.011
single organism cellular localization GO:1902580 46 0.011
interspecies interaction between organisms GO:0044419 4 0.011
transmembrane transport GO:0055085 120 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
alcohol biosynthetic process GO:0046165 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
organelle fusion GO:0048284 3 0.011
regulation of molecular function GO:0065009 70 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
regulation of endocrine process GO:0044060 2 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
regulation of transcription dna templated GO:0006355 213 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
startle response GO:0001964 4 0.010
action potential GO:0001508 19 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
macroautophagy GO:0016236 1 0.010
regulation of organ growth GO:0046620 3 0.010
cell cycle arrest GO:0007050 1 0.010
rho protein signal transduction GO:0007266 5 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
heart morphogenesis GO:0003007 156 0.010
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.010
peptidyl serine modification GO:0018209 2 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
angiogenesis GO:0001525 158 0.010
regulation of stem cell proliferation GO:0072091 2 0.010

pde6d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
cardiovascular system disease DOID:1287 0 0.011