Danio rerio

0 known processes

si:dkey-117i6.1

si:dkey-117i6.1

si:dkey-117i6.1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.057
synaptic growth at neuromuscular junction GO:0051124 2 0.042
positive regulation of transport GO:0051050 2 0.041
response to monosaccharide GO:0034284 3 0.038
cognition GO:0050890 1 0.038
regulation of synapse organization GO:0050807 3 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.037
aging GO:0007568 2 0.034
regulation of synaptic plasticity GO:0048167 1 0.032
sensory perception of chemical stimulus GO:0007606 3 0.032
cellular component movement GO:0006928 335 0.032
locomotion GO:0040011 313 0.031
regulation of stem cell differentiation GO:2000736 4 0.031
response to hexose GO:0009746 3 0.031
regulation of reproductive process GO:2000241 4 0.031
central nervous system development GO:0007417 387 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
response to glucose GO:0009749 3 0.030
cellular component morphogenesis GO:0032989 336 0.030
cellular response to external stimulus GO:0071496 2 0.030
compound eye development GO:0048749 2 0.030
sleep GO:0030431 1 0.029
response to carbohydrate GO:0009743 3 0.029
morphogenesis of an epithelium GO:0002009 333 0.028
cell surface receptor signaling pathway GO:0007166 325 0.027
phagocytosis GO:0006909 3 0.027
positive regulation of cell cycle GO:0045787 3 0.026
regulation of cytokine production GO:0001817 3 0.026
response to chemical GO:0042221 320 0.026
guanosine containing compound metabolic process GO:1901068 4 0.025
regulation of protein transport GO:0051223 3 0.025
neuromuscular synaptic transmission GO:0007274 2 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
oocyte maturation GO:0001556 4 0.024
regulation of synapse assembly GO:0051963 3 0.024
brain development GO:0007420 293 0.024
cellular protein catabolic process GO:0044257 4 0.024
regulation of endocrine process GO:0044060 2 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.024
response to external stimulus GO:0009605 264 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.023
response to drug GO:0042493 3 0.023
nuclear transport GO:0051169 4 0.023
synaptic transmission cholinergic GO:0007271 4 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
signal transduction GO:0007165 455 0.023
regulation of blood pressure GO:0008217 1 0.023
cellular response to nutrient levels GO:0031669 2 0.023
positive regulation of catabolic process GO:0009896 4 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
nucleocytoplasmic transport GO:0006913 4 0.022
tube morphogenesis GO:0035239 349 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of neuronal synaptic plasticity GO:0048168 1 0.022
regulation of protein complex assembly GO:0043254 3 0.022
head development GO:0060322 303 0.022
protein import into nucleus GO:0006606 3 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
post embryonic organ development GO:0048569 4 0.022
stem cell maintenance GO:0019827 4 0.022
amine metabolic process GO:0009308 2 0.022
nuclear export GO:0051168 1 0.021
protein targeting to nucleus GO:0044744 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
somatic muscle development GO:0007525 4 0.021
regulation of cell shape GO:0008360 1 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
protein secretion GO:0009306 1 0.021
chemosensory behavior GO:0007635 1 0.021
protein localization to nucleus GO:0034504 3 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.020
adult behavior GO:0030534 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of cell activation GO:0050865 1 0.020
female sex differentiation GO:0046660 4 0.020
cellular lipid catabolic process GO:0044242 3 0.020
gtp metabolic process GO:0046039 4 0.020
regulation of cell communication GO:0010646 232 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
digestive system development GO:0055123 289 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
regulation of blood vessel size GO:0050880 2 0.019
system process GO:0003008 185 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
cellular component maintenance GO:0043954 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
cell part morphogenesis GO:0032990 246 0.019
single organism localization GO:1902578 225 0.019
secondary metabolic process GO:0019748 3 0.019
single organism metabolic process GO:0044710 217 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
cellular response to starvation GO:0009267 1 0.019
gastrulation GO:0007369 208 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
positive regulation of biological process GO:0048518 253 0.018
regulation of gtpase activity GO:0043087 2 0.018
multi organism process GO:0051704 134 0.018
negative regulation of kinase activity GO:0033673 4 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
water transport GO:0006833 15 0.018
generation of neurons GO:0048699 385 0.018
cell substrate adhesion GO:0031589 4 0.018
maintenance of location GO:0051235 4 0.018
digestive tract development GO:0048565 265 0.018
golgi vesicle transport GO:0048193 3 0.018
negative regulation of stem cell differentiation GO:2000737 2 0.018
nuclear import GO:0051170 3 0.017
stem cell proliferation GO:0072089 4 0.017
regulation of metal ion transport GO:0010959 4 0.017
negative regulation of catabolic process GO:0009895 3 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
rna metabolic process GO:0016070 219 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
mechanosensory behavior GO:0007638 2 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cell projection organization GO:0030030 284 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
female gonad development GO:0008585 4 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
gtp catabolic process GO:0006184 2 0.017
protein import GO:0017038 3 0.016
neurotransmitter transport GO:0006836 2 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
neuron differentiation GO:0030182 353 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
cell morphogenesis GO:0000902 289 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of tube size GO:0035150 2 0.016
multicellular organism growth GO:0035264 4 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
biosynthetic process GO:0009058 294 0.016
somatic stem cell maintenance GO:0035019 1 0.016
negative regulation of protein transport GO:0051224 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cell motility GO:0048870 244 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
embryonic organ development GO:0048568 381 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
establishment of localization GO:0051234 244 0.015
cell projection morphogenesis GO:0048858 244 0.015
negative regulation of reproductive process GO:2000242 3 0.015
rhombomere 5 development GO:0021571 4 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of transporter activity GO:0032409 2 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
regulation of cell development GO:0060284 100 0.015
peptide transport GO:0015833 1 0.015
membrane fusion GO:0061025 2 0.015
smooth muscle contraction GO:0006939 2 0.015
regulation of metabolic process GO:0019222 359 0.015
lateral inhibition GO:0046331 1 0.015
stem cell division GO:0017145 1 0.015
regulation of protein targeting GO:1903533 2 0.015
interspecies interaction between organisms GO:0044419 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
regulation of dendrite development GO:0050773 3 0.015
actin filament based movement GO:0030048 1 0.015
heterocycle metabolic process GO:0046483 290 0.015
positive regulation of secretion GO:0051047 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
cellular macromolecule metabolic process GO:0044260 391 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cellular component disassembly GO:0022411 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cytokinesis GO:0000910 3 0.014
positive regulation of cellular process GO:0048522 201 0.014
sequestering of metal ion GO:0051238 3 0.014
atp catabolic process GO:0006200 4 0.014
protein metabolic process GO:0019538 183 0.014
localization of cell GO:0051674 244 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
hormone transport GO:0009914 2 0.014
small molecule metabolic process GO:0044281 77 0.014
positive regulation of neuron apoptotic process GO:0043525 1 0.014
positive regulation of neuron death GO:1901216 1 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
leukocyte proliferation GO:0070661 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
carbohydrate homeostasis GO:0033500 1 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
sensory perception of smell GO:0007608 2 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
rna localization GO:0006403 4 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
detection of chemical stimulus involved in sensory perception GO:0050907 3 0.013
hormone secretion GO:0046879 2 0.013
developmental growth GO:0048589 166 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
chordate embryonic development GO:0043009 271 0.013
sensory organ development GO:0007423 393 0.013
response to alkaloid GO:0043279 2 0.013
lymphocyte proliferation GO:0046651 1 0.013
gene expression GO:0010467 252 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
microtubule organizing center organization GO:0031023 1 0.013
apoptotic process involved in development GO:1902742 2 0.013
single organism nuclear import GO:1902593 3 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
centrosome cycle GO:0007098 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
exocytosis GO:0006887 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
determination of bilateral symmetry GO:0009855 204 0.013
cellular ketone metabolic process GO:0042180 11 0.013
cell fate commitment GO:0045165 99 0.013
protein complex disassembly GO:0043241 1 0.013
cellular component biogenesis GO:0044085 178 0.013
protein localization to plasma membrane GO:0072659 1 0.013
membrane invagination GO:0010324 1 0.013
eye development GO:0001654 277 0.013
positive regulation of notch signaling pathway GO:0045747 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
mononuclear cell proliferation GO:0032943 1 0.013
negative regulation of gliogenesis GO:0014014 1 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
cell migration GO:0016477 237 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
negative regulation of mapk cascade GO:0043409 4 0.012
positive regulation of multi organism process GO:0043902 3 0.012
one carbon compound transport GO:0019755 14 0.012
taxis GO:0042330 109 0.012
tissue remodeling GO:0048771 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of mrna processing GO:0050684 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
angiogenesis GO:0001525 158 0.012
neuroblast proliferation GO:0007405 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
convergent extension GO:0060026 118 0.012
lipid catabolic process GO:0016042 4 0.012
meiotic nuclear division GO:0007126 4 0.012
phagocytosis engulfment GO:0006911 1 0.012
carbon dioxide transport GO:0015670 3 0.012
regulation of binding GO:0051098 3 0.012
spermatid development GO:0007286 2 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
single organism organelle organization GO:1902589 199 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
pigment granule localization GO:0051875 25 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of cell projection assembly GO:0060491 4 0.012
organic substance biosynthetic process GO:1901576 289 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
regulation of biological quality GO:0065008 263 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of intracellular ph GO:0051453 1 0.012
actin mediated cell contraction GO:0070252 1 0.012
protein acetylation GO:0006473 2 0.012
regulation of ph GO:0006885 3 0.012
glucose homeostasis GO:0042593 1 0.012
multi organism cellular process GO:0044764 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
b cell activation GO:0042113 2 0.012
autophagy GO:0006914 4 0.012
nucleic acid metabolic process GO:0090304 244 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
neuron projection development GO:0031175 180 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
synaptic target recognition GO:0008039 1 0.011
lamellipodium organization GO:0097581 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
cell cell recognition GO:0009988 1 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
response to stress GO:0006950 263 0.011
anatomical structure arrangement GO:0048532 2 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
tube closure GO:0060606 1 0.011
protein acylation GO:0043543 3 0.011
primary neural tube formation GO:0014020 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
rhombomere 5 morphogenesis GO:0021664 1 0.011
post embryonic morphogenesis GO:0009886 4 0.011
regulation of gene expression GO:0010468 265 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
mitochondrion organization GO:0007005 4 0.011
neurological system process GO:0050877 62 0.011
hemopoiesis GO:0030097 183 0.011
immune system process GO:0002376 241 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
viral process GO:0016032 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
protein modification process GO:0036211 100 0.011
synaptic vesicle transport GO:0048489 1 0.011
single organism membrane fusion GO:0044801 2 0.011
response to food GO:0032094 1 0.011
organelle fusion GO:0048284 3 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of neurological system process GO:0031644 2 0.011
regulation of transcription dna templated GO:0006355 213 0.011
locomotor rhythm GO:0045475 3 0.011
rna transport GO:0050658 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.010
transcription dna templated GO:0006351 181 0.010
gas transport GO:0015669 3 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
kidney development GO:0001822 92 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
response to corticosteroid GO:0031960 1 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
er nucleus signaling pathway GO:0006984 2 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
single fertilization GO:0007338 3 0.010
regulation of signaling GO:0023051 235 0.010
regulation of jak stat cascade GO:0046425 3 0.010
positive regulation of cell killing GO:0031343 2 0.010
growth GO:0040007 174 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
germ line stem cell maintenance GO:0030718 2 0.010
cell matrix adhesion GO:0007160 4 0.010
neuron development GO:0048666 262 0.010
regulation of organ growth GO:0046620 3 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
regulation of cellular biosynthetic process GO:0031326 245 0.010
ion transmembrane transport GO:0034220 91 0.010

si:dkey-117i6.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.011
musculoskeletal system disease DOID:17 0 0.010
charcot marie tooth disease type 4 DOID:0050541 0 0.010
neuromuscular disease DOID:440 0 0.010
charcot marie tooth disease DOID:10595 0 0.010
neuropathy DOID:870 0 0.010