Danio rerio

0 known processes

apip

APAF1 interacting protein

(Aliases: zgc:103619)

apip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.089
aging GO:0007568 2 0.055
positive regulation of transport GO:0051050 2 0.044
multicellular organism growth GO:0035264 4 0.039
maintenance of location GO:0051235 4 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
guanosine containing compound catabolic process GO:1901069 2 0.034
autophagy GO:0006914 4 0.034
cellular response to nutrient levels GO:0031669 2 0.033
nitrogen compound metabolic process GO:0006807 319 0.032
cellular response to extracellular stimulus GO:0031668 2 0.031
cellular response to external stimulus GO:0071496 2 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
gtp metabolic process GO:0046039 4 0.031
neuron differentiation GO:0030182 353 0.031
organelle fusion GO:0048284 3 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
carboxylic acid catabolic process GO:0046395 3 0.031
response to chemical GO:0042221 320 0.031
cognition GO:0050890 1 0.031
cellular response to starvation GO:0009267 1 0.031
mitochondrion organization GO:0007005 4 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
establishment of protein localization to organelle GO:0072594 4 0.029
amine metabolic process GO:0009308 2 0.029
small molecule metabolic process GO:0044281 77 0.029
organic acid catabolic process GO:0016054 3 0.029
phagocytosis GO:0006909 3 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
regulation of protein complex assembly GO:0043254 3 0.028
cellular protein catabolic process GO:0044257 4 0.028
proteasomal protein catabolic process GO:0010498 2 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
single organism membrane fusion GO:0044801 2 0.027
protein localization to nucleus GO:0034504 3 0.027
generation of neurons GO:0048699 385 0.027
positive regulation of catabolic process GO:0009896 4 0.027
cellular macromolecule metabolic process GO:0044260 391 0.026
membrane fusion GO:0061025 2 0.026
protein import GO:0017038 3 0.026
meiotic cell cycle process GO:1903046 3 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
cell part morphogenesis GO:0032990 246 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
nuclear transport GO:0051169 4 0.026
organic cyclic compound metabolic process GO:1901360 301 0.025
cellular amine metabolic process GO:0044106 2 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
heterocycle metabolic process GO:0046483 290 0.025
xenobiotic metabolic process GO:0006805 4 0.025
protein targeting to nucleus GO:0044744 3 0.025
meiotic nuclear division GO:0007126 4 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
gtp catabolic process GO:0006184 2 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
cytokinesis GO:0000910 3 0.024
regulation of metal ion transport GO:0010959 4 0.024
single organism metabolic process GO:0044710 217 0.024
small molecule catabolic process GO:0044282 3 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
cell projection organization GO:0030030 284 0.024
positive regulation of cell cycle GO:0045787 3 0.024
lipid storage GO:0019915 1 0.024
regulation of binding GO:0051098 3 0.023
regulation of protein targeting GO:1903533 2 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
regulation of protein transport GO:0051223 3 0.023
secondary metabolic process GO:0019748 3 0.023
single organism nuclear import GO:1902593 3 0.023
neuron development GO:0048666 262 0.023
endosomal transport GO:0016197 2 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
gene expression GO:0010467 252 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
regulation of transporter activity GO:0032409 2 0.022
stem cell maintenance GO:0019827 4 0.022
cell projection morphogenesis GO:0048858 244 0.022
regulation of primary metabolic process GO:0080090 311 0.022
nucleic acid metabolic process GO:0090304 244 0.022
response to external stimulus GO:0009605 264 0.022
organonitrogen compound metabolic process GO:1901564 74 0.021
neurotransmitter secretion GO:0007269 2 0.021
regulation of cytokine production GO:0001817 3 0.021
protein import into nucleus GO:0006606 3 0.021
protein localization to plasma membrane GO:0072659 1 0.021
nuclear import GO:0051170 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
negative regulation of biological process GO:0048519 304 0.020
stem cell proliferation GO:0072089 4 0.020
signal transduction GO:0007165 455 0.020
cellular component morphogenesis GO:0032989 336 0.020
rna metabolic process GO:0016070 219 0.020
macroautophagy GO:0016236 1 0.020
chordate embryonic development GO:0043009 271 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
golgi vesicle transport GO:0048193 3 0.020
establishment of localization GO:0051234 244 0.020
cellular component movement GO:0006928 335 0.020
regulation of metabolic process GO:0019222 359 0.020
neurotransmitter transport GO:0006836 2 0.019
organic acid metabolic process GO:0006082 31 0.019
vasculature development GO:0001944 278 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
organic substance biosynthetic process GO:1901576 289 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
cellular component disassembly GO:0022411 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
regulation of synapse assembly GO:0051963 3 0.019
protein metabolic process GO:0019538 183 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
positive regulation of secretion GO:0051047 1 0.019
tube morphogenesis GO:0035239 349 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
response to stress GO:0006950 263 0.018
oxoacid metabolic process GO:0043436 31 0.018
protein secretion GO:0009306 1 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
organelle organization GO:0006996 227 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
cell substrate adhesion GO:0031589 4 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
biosynthetic process GO:0009058 294 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
axon development GO:0061564 166 0.018
response to drug GO:0042493 3 0.018
sensory organ development GO:0007423 393 0.017
regulation of signaling GO:0023051 235 0.017
membrane invagination GO:0010324 1 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
regulation of cell communication GO:0010646 232 0.017
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.017
compound eye development GO:0048749 2 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
neuron projection development GO:0031175 180 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
single organism localization GO:1902578 225 0.017
embryonic organ development GO:0048568 381 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
regulation of cell shape GO:0008360 1 0.017
regulation of autophagy GO:0010506 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
cell morphogenesis GO:0000902 289 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
cellular amide metabolic process GO:0043603 4 0.017
centrosome organization GO:0051297 1 0.016
transport GO:0006810 220 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
phagocytosis engulfment GO:0006911 1 0.016
response to uv GO:0009411 3 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
macromolecular complex disassembly GO:0032984 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
interspecies interaction between organisms GO:0044419 4 0.016
meiotic chromosome segregation GO:0045132 3 0.016
locomotion GO:0040011 313 0.016
regulation of rna metabolic process GO:0051252 224 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
peptide metabolic process GO:0006518 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
head development GO:0060322 303 0.016
regulation of cell activation GO:0050865 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
lipid catabolic process GO:0016042 4 0.016
central nervous system development GO:0007417 387 0.016
axonogenesis GO:0007409 152 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
cellular protein metabolic process GO:0044267 129 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
chemosensory behavior GO:0007635 1 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of protein catabolic process GO:0042176 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
blood vessel development GO:0001568 246 0.015
regulation of dendrite development GO:0050773 3 0.015
brain development GO:0007420 293 0.015
multi organism cellular process GO:0044764 2 0.015
tissue remodeling GO:0048771 4 0.015
exocytosis GO:0006887 1 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
synaptic vesicle transport GO:0048489 1 0.015
single organism transport GO:0044765 206 0.015
regulation of reproductive process GO:2000241 4 0.015
protein complex disassembly GO:0043241 1 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
regulation of gtpase activity GO:0043087 2 0.015
nucleic acid templated transcription GO:0097659 181 0.015
cellular component biogenesis GO:0044085 178 0.015
spermatid development GO:0007286 2 0.015
regulation of synapse organization GO:0050807 3 0.015
protein acetylation GO:0006473 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
calcium ion transport into cytosol GO:0060402 3 0.015
cell surface receptor signaling pathway GO:0007166 325 0.014
heart development GO:0007507 313 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
protein polyubiquitination GO:0000209 4 0.014
apoptotic process GO:0006915 116 0.014
rna biosynthetic process GO:0032774 181 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
atp catabolic process GO:0006200 4 0.014
regulation of response to stimulus GO:0048583 269 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
fertilization GO:0009566 3 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
adult behavior GO:0030534 2 0.014
positive regulation of cytokine production GO:0001819 2 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
single fertilization GO:0007338 3 0.014
sequestering of calcium ion GO:0051208 3 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of biosynthetic process GO:0009889 250 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of neurotransmitter transport GO:0051588 1 0.013
response to nutrient GO:0007584 3 0.013
positive regulation of cell activation GO:0050867 1 0.013
organelle assembly GO:0070925 110 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
positive regulation of immune effector process GO:0002699 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
stem cell division GO:0017145 1 0.013
spermatid differentiation GO:0048515 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
regulation of mrna processing GO:0050684 3 0.013
protein acylation GO:0043543 3 0.013
cellular response to radiation GO:0071478 4 0.013
cellular lipid catabolic process GO:0044242 3 0.013
regulation of calcium ion transport GO:0051924 2 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
negative regulation of catabolic process GO:0009895 3 0.013
lateral inhibition GO:0046331 1 0.013
growth GO:0040007 174 0.013
response to alkaloid GO:0043279 2 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
viral process GO:0016032 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
sequestering of metal ion GO:0051238 3 0.013
alcohol biosynthetic process GO:0046165 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
monocarboxylic acid catabolic process GO:0072329 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of transcription dna templated GO:0006355 213 0.012
response to hexose GO:0009746 3 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
single organism organelle organization GO:1902589 199 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
primary neural tube formation GO:0014020 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
transcription dna templated GO:0006351 181 0.012
cellular localization GO:0051641 97 0.012
mitotic g2 m transition checkpoint GO:0044818 3 0.012
peptidyl serine modification GO:0018209 2 0.012
cellular biosynthetic process GO:0044249 286 0.012
cellular response to stress GO:0033554 62 0.012
lipid oxidation GO:0034440 1 0.012
peptide transport GO:0015833 1 0.012
system process GO:0003008 185 0.012
developmental growth GO:0048589 166 0.012
protein homooligomerization GO:0051260 3 0.012
regulation of signal transduction GO:0009966 225 0.012
blood vessel morphogenesis GO:0048514 216 0.012
carbohydrate homeostasis GO:0033500 1 0.012
programmed cell death GO:0012501 119 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
death GO:0016265 121 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
negative regulation of cytokine production GO:0001818 1 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
adherens junction organization GO:0034332 4 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
cell death GO:0008219 121 0.012
tube closure GO:0060606 1 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
female meiotic division GO:0007143 2 0.012
response to topologically incorrect protein GO:0035966 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
rna localization GO:0006403 4 0.012
vacuolar transport GO:0007034 2 0.012
cellular component assembly GO:0022607 170 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
response to glucose GO:0009749 3 0.012
regulation of gene expression GO:0010468 265 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
rna transport GO:0050658 2 0.012
regulation of developmental process GO:0050793 247 0.012
multi organism process GO:0051704 134 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
mitochondrial transport GO:0006839 2 0.012
centrosome cycle GO:0007098 1 0.012
immune system process GO:0002376 241 0.012
cellular response to xenobiotic stimulus GO:0071466 35 0.011
determination of left right symmetry GO:0007368 179 0.011
cell migration GO:0016477 237 0.011
female sex differentiation GO:0046660 4 0.011
cytoplasm organization GO:0007028 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
cell matrix adhesion GO:0007160 4 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
leukocyte proliferation GO:0070661 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
cilium organization GO:0044782 71 0.011
gland development GO:0048732 143 0.011
hemopoiesis GO:0030097 183 0.011
mononuclear cell proliferation GO:0032943 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
translational initiation GO:0006413 3 0.011
regulation of circadian rhythm GO:0042752 4 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
somite development GO:0061053 96 0.011
cytokinetic process GO:0032506 2 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
regionalization GO:0003002 274 0.011
glucose homeostasis GO:0042593 1 0.011
cellular response to hypoxia GO:0071456 1 0.011
cilium assembly GO:0042384 58 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
b cell activation GO:0042113 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
negative regulation of signal transduction GO:0009968 94 0.011
double strand break repair GO:0006302 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
homeostatic process GO:0042592 142 0.011
eye development GO:0001654 277 0.011
nucleic acid transport GO:0050657 2 0.011
regulation of chromosome segregation GO:0051983 1 0.011
regulation of neurogenesis GO:0050767 87 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
protein polymerization GO:0051258 4 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
digestive system development GO:0055123 289 0.011
response to unfolded protein GO:0006986 2 0.011
sleep GO:0030431 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
determination of bilateral symmetry GO:0009855 204 0.011
cellular response to oxygen levels GO:0071453 1 0.011
cell motility GO:0048870 244 0.011
female gonad development GO:0008585 4 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
nucleobase containing compound transport GO:0015931 2 0.010
convergent extension GO:0060026 118 0.010
er to golgi vesicle mediated transport GO:0006888 1 0.010
regulation of biological quality GO:0065008 263 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
response to organic substance GO:0010033 153 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
neuroblast proliferation GO:0007405 2 0.010
negative regulation of cell communication GO:0010648 96 0.010
cellular response to topologically incorrect protein GO:0035967 2 0.010
regulation of sodium ion transport GO:0002028 2 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
antimicrobial humoral response GO:0019730 2 0.010
specification of symmetry GO:0009799 204 0.010
intracellular mrna localization GO:0008298 1 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
muscle structure development GO:0061061 196 0.010
negative regulation of multi organism process GO:0043901 3 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
ovulation cycle GO:0042698 2 0.010
negative regulation of signaling GO:0023057 96 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
somatic stem cell maintenance GO:0035019 1 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
positive regulation of multi organism process GO:0043902 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
synaptic vesicle recycling GO:0036465 1 0.010
regulation of apoptotic process GO:0042981 98 0.010

apip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.013
immune system disease DOID:2914 0 0.012
inherited metabolic disorder DOID:655 0 0.011