Danio rerio

0 known processes

mapk8a

mitogen-activated protein kinase 8a

(Aliases: zgc:172209)

mapk8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.091
signal transduction GO:0007165 455 0.060
heterocycle metabolic process GO:0046483 290 0.051
aging GO:0007568 2 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.043
cognition GO:0050890 1 0.040
embryonic organ development GO:0048568 381 0.040
positive regulation of cell cycle GO:0045787 3 0.039
cell surface receptor signaling pathway GO:0007166 325 0.036
multicellular organism growth GO:0035264 4 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.035
regulation of response to stimulus GO:0048583 269 0.035
phagocytosis GO:0006909 3 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
positive regulation of transport GO:0051050 2 0.035
tube morphogenesis GO:0035239 349 0.035
gtp metabolic process GO:0046039 4 0.033
sensory organ development GO:0007423 393 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
regulation of cellular metabolic process GO:0031323 320 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
stem cell maintenance GO:0019827 4 0.032
organic substance biosynthetic process GO:1901576 289 0.032
maintenance of location GO:0051235 4 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
autophagy GO:0006914 4 0.031
nucleic acid metabolic process GO:0090304 244 0.031
regulation of biosynthetic process GO:0009889 250 0.030
cellular protein catabolic process GO:0044257 4 0.030
embryonic organ morphogenesis GO:0048562 274 0.030
gtp catabolic process GO:0006184 2 0.030
regulation of signaling GO:0023051 235 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
cellular response to external stimulus GO:0071496 2 0.029
guanosine containing compound metabolic process GO:1901068 4 0.028
regulation of cytokine production GO:0001817 3 0.028
regulation of signal transduction GO:0009966 225 0.028
regulation of protein catabolic process GO:0042176 1 0.028
regulation of metabolic process GO:0019222 359 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
system process GO:0003008 185 0.028
mitochondrion organization GO:0007005 4 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.027
biosynthetic process GO:0009058 294 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
cellular biosynthetic process GO:0044249 286 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
regulation of cell communication GO:0010646 232 0.027
single organism metabolic process GO:0044710 217 0.027
negative regulation of cellular process GO:0048523 283 0.027
positive regulation of catabolic process GO:0009896 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
positive regulation of biological process GO:0048518 253 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.025
amine metabolic process GO:0009308 2 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
regulation of gene expression GO:0010468 265 0.025
response to chemical GO:0042221 320 0.025
heart development GO:0007507 313 0.024
digestive system development GO:0055123 289 0.024
regulation of primary metabolic process GO:0080090 311 0.024
rna metabolic process GO:0016070 219 0.024
hormone secretion GO:0046879 2 0.024
i kappab kinase nf kappab signaling GO:0007249 4 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.023
cell projection morphogenesis GO:0048858 244 0.023
regulation of protein transport GO:0051223 3 0.023
cellular response to nutrient levels GO:0031669 2 0.023
gene expression GO:0010467 252 0.023
tissue remodeling GO:0048771 4 0.023
negative regulation of biological process GO:0048519 304 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
blood vessel morphogenesis GO:0048514 216 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
adult behavior GO:0030534 2 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of protein complex assembly GO:0043254 3 0.023
cellular amine metabolic process GO:0044106 2 0.023
oxoacid metabolic process GO:0043436 31 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
immune system process GO:0002376 241 0.022
eye development GO:0001654 277 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
stem cell proliferation GO:0072089 4 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
cell morphogenesis GO:0000902 289 0.021
response to stress GO:0006950 263 0.021
cellular component biogenesis GO:0044085 178 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
response to corticosteroid GO:0031960 1 0.021
immune system development GO:0002520 191 0.021
regulation of synapse organization GO:0050807 3 0.021
organelle fusion GO:0048284 3 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.020
regionalization GO:0003002 274 0.020
regulation of cell activation GO:0050865 1 0.020
response to drug GO:0042493 3 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
regulation of circadian rhythm GO:0042752 4 0.020
single organism nuclear import GO:1902593 3 0.020
nuclear transport GO:0051169 4 0.020
centrosome organization GO:0051297 1 0.020
regulation of reproductive process GO:2000241 4 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
cellular component movement GO:0006928 335 0.020
antimicrobial humoral response GO:0019730 2 0.020
vasculature development GO:0001944 278 0.020
cellular response to starvation GO:0009267 1 0.020
regulation of developmental process GO:0050793 247 0.020
positive regulation of cellular process GO:0048522 201 0.020
hemopoiesis GO:0030097 183 0.020
regulation of autophagy GO:0010506 3 0.020
response to monosaccharide GO:0034284 3 0.020
protein localization to nucleus GO:0034504 3 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
organic acid metabolic process GO:0006082 31 0.019
cell projection organization GO:0030030 284 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
regulation of biological quality GO:0065008 263 0.019
locomotion GO:0040011 313 0.019
membrane fusion GO:0061025 2 0.019
central nervous system development GO:0007417 387 0.019
protein targeting to nucleus GO:0044744 3 0.019
positive regulation of secretion GO:0051047 1 0.019
carbohydrate homeostasis GO:0033500 1 0.019
regulation of cell shape GO:0008360 1 0.019
cellular component morphogenesis GO:0032989 336 0.019
protein metabolic process GO:0019538 183 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
locomotor rhythm GO:0045475 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
hormone transport GO:0009914 2 0.019
establishment of localization GO:0051234 244 0.019
liver development GO:0001889 96 0.019
transcription dna templated GO:0006351 181 0.018
microtubule organizing center organization GO:0031023 1 0.018
regulation of transcription dna templated GO:0006355 213 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
single organism membrane fusion GO:0044801 2 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of rna metabolic process GO:0051252 224 0.018
head development GO:0060322 303 0.018
neurotransmitter transport GO:0006836 2 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
exocytosis GO:0006887 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
response to hexose GO:0009746 3 0.018
negative regulation of kinase activity GO:0033673 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
determination of bilateral symmetry GO:0009855 204 0.017
single organism organelle organization GO:1902589 199 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
neuron differentiation GO:0030182 353 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
response to alkaloid GO:0043279 2 0.017
cell substrate adhesion GO:0031589 4 0.017
cellular component assembly GO:0022607 170 0.017
compound eye development GO:0048749 2 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
lipid storage GO:0019915 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
digestive tract morphogenesis GO:0048546 231 0.017
atp catabolic process GO:0006200 4 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
glucose homeostasis GO:0042593 1 0.017
membrane invagination GO:0010324 1 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
cytokinesis GO:0000910 3 0.017
growth GO:0040007 174 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
cell part morphogenesis GO:0032990 246 0.017
organelle organization GO:0006996 227 0.017
phagocytosis engulfment GO:0006911 1 0.017
gastrulation GO:0007369 208 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
response to ketone GO:1901654 1 0.016
rna biosynthetic process GO:0032774 181 0.016
meiotic cell cycle process GO:1903046 3 0.016
peptide transport GO:0015833 1 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of metal ion transport GO:0010959 4 0.016
specification of symmetry GO:0009799 204 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
cellular ketone metabolic process GO:0042180 11 0.016
single organism localization GO:1902578 225 0.016
peptide metabolic process GO:0006518 1 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
nucleic acid templated transcription GO:0097659 181 0.016
response to external stimulus GO:0009605 264 0.016
regulation of organelle assembly GO:1902115 4 0.016
protein import into nucleus GO:0006606 3 0.016
sensory organ morphogenesis GO:0090596 200 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
response to organic substance GO:0010033 153 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
response to carbohydrate GO:0009743 3 0.015
nuclear import GO:0051170 3 0.015
regulation of synapse assembly GO:0051963 3 0.015
response to uv GO:0009411 3 0.015
camera type eye development GO:0043010 222 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
pigment granule localization GO:0051875 25 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
cellular amide metabolic process GO:0043603 4 0.015
response to glucose GO:0009749 3 0.015
generation of neurons GO:0048699 385 0.015
response to endogenous stimulus GO:0009719 83 0.015
connective tissue development GO:0061448 99 0.015
macroautophagy GO:0016236 1 0.015
cell migration GO:0016477 237 0.015
peptidyl serine modification GO:0018209 2 0.015
angiogenesis GO:0001525 158 0.015
transport GO:0006810 220 0.015
muscle structure development GO:0061061 196 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of intracellular protein transport GO:0033157 3 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
rna localization GO:0006403 4 0.014
organism emergence from protective structure GO:0071684 4 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
leukocyte proliferation GO:0070661 1 0.014
cellular response to light stimulus GO:0071482 4 0.014
organelle assembly GO:0070925 110 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
protein import GO:0017038 3 0.014
single organism transport GO:0044765 206 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of binding GO:0051098 3 0.014
hepaticobiliary system development GO:0061008 98 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
mitochondrial transport GO:0006839 2 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
microtubule based movement GO:0007018 33 0.014
protein polymerization GO:0051258 4 0.014
cellular response to radiation GO:0071478 4 0.014
lipid catabolic process GO:0016042 4 0.014
cell matrix adhesion GO:0007160 4 0.014
regulation of organ growth GO:0046620 3 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
secondary metabolic process GO:0019748 3 0.014
blood vessel development GO:0001568 246 0.014
response to glucocorticoid GO:0051384 1 0.013
protein dephosphorylation GO:0006470 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
neurological system process GO:0050877 62 0.013
digestive tract development GO:0048565 265 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
b cell activation GO:0042113 2 0.013
negative regulation of defense response GO:0031348 2 0.013
protein secretion GO:0009306 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
blood circulation GO:0008015 87 0.013
positive regulation of translation GO:0045727 1 0.013
golgi vesicle transport GO:0048193 3 0.013
cilium morphogenesis GO:0060271 85 0.013
meiotic nuclear division GO:0007126 4 0.013
female sex differentiation GO:0046660 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
neuron development GO:0048666 262 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
gland development GO:0048732 143 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
intracellular signal transduction GO:0035556 85 0.012
ion transmembrane transport GO:0034220 91 0.012
cilium organization GO:0044782 71 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
cellular component disassembly GO:0022411 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
regulation of dendrite development GO:0050773 3 0.012
adherens junction organization GO:0034332 4 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
protein modification process GO:0036211 100 0.012
transmembrane transport GO:0055085 120 0.012
cell cycle g2 m phase transition GO:0044839 4 0.012
ovulation cycle process GO:0022602 2 0.012
negative regulation of reproductive process GO:2000242 3 0.012
regulation of protein targeting GO:1903533 2 0.012
cell motility GO:0048870 244 0.012
homeostatic process GO:0042592 142 0.012
striated muscle tissue development GO:0014706 110 0.012
regulation of blood vessel size GO:0050880 2 0.012
brain development GO:0007420 293 0.012
regulation of muscle contraction GO:0006937 3 0.012
developmental programmed cell death GO:0010623 4 0.012
positive regulation of cell activation GO:0050867 1 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
regulation of protein polymerization GO:0032271 2 0.012
localization of cell GO:0051674 244 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
multi organism process GO:0051704 134 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
cellular protein metabolic process GO:0044267 129 0.012
endocrine process GO:0050886 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
regulation of inflammatory response GO:0050727 2 0.012
regulation of protein binding GO:0043393 3 0.011
retina development in camera type eye GO:0060041 146 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
regulation of endocrine process GO:0044060 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
endosomal transport GO:0016197 2 0.011
response to other organism GO:0051707 97 0.011
regulation of hormone secretion GO:0046883 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
inner ear development GO:0048839 126 0.011
phototransduction GO:0007602 2 0.011
cilium assembly GO:0042384 58 0.011
regulation of gtpase activity GO:0043087 2 0.011
macromolecule modification GO:0043412 111 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
wnt signaling pathway GO:0016055 80 0.011
cellular response to hypoxia GO:0071456 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
skeletal system development GO:0001501 181 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
meiotic chromosome segregation GO:0045132 3 0.011
cartilage development GO:0051216 96 0.011
somatic stem cell maintenance GO:0035019 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
centrosome cycle GO:0007098 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of cell differentiation GO:0045595 142 0.011
mononuclear cell proliferation GO:0032943 1 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
response to nutrient GO:0007584 3 0.010
cellular response to xenobiotic stimulus GO:0071466 35 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
cellular pigmentation GO:0033059 30 0.010
developmental growth GO:0048589 166 0.010
regulation of cell projection assembly GO:0060491 4 0.010
cell substrate junction assembly GO:0007044 2 0.010
regulation of tube size GO:0035150 2 0.010
protein localization to plasma membrane GO:0072659 1 0.010
cell projection assembly GO:0030031 64 0.010
synaptic vesicle localization GO:0097479 1 0.010
regulation of blood pressure GO:0008217 1 0.010
actin filament polymerization GO:0030041 2 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
negative regulation of protein transport GO:0051224 3 0.010
apoptotic process involved in development GO:1902742 2 0.010
heart morphogenesis GO:0003007 156 0.010
protein homooligomerization GO:0051260 3 0.010
lipid homeostasis GO:0055088 3 0.010
hatching GO:0035188 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
pectoral fin development GO:0033339 50 0.010
eye morphogenesis GO:0048592 144 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cell death GO:0008219 121 0.010
ear development GO:0043583 127 0.010

mapk8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
cardiovascular system disease DOID:1287 0 0.013
disease of metabolism DOID:0014667 0 0.012
retinal disease DOID:5679 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
immune system disease DOID:2914 0 0.011