Danio rerio

0 known processes

dia1

diaphorase (NADH) (cytochrome b-5 reductase)

(Aliases: MGC56042,wu:fb15h03,zgc:56042,CYB5R1,wu:fb13e02)

dia1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.080
multicellular organism growth GO:0035264 4 0.066
aging GO:0007568 2 0.047
cellular macromolecule metabolic process GO:0044260 391 0.047
heterocycle metabolic process GO:0046483 290 0.045
maintenance of location GO:0051235 4 0.044
guanosine containing compound metabolic process GO:1901068 4 0.038
response to stress GO:0006950 263 0.037
system process GO:0003008 185 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
gtp metabolic process GO:0046039 4 0.034
cellular respiration GO:0045333 3 0.033
regulation of multicellular organism growth GO:0040014 4 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.032
regulation of cytokine production GO:0001817 3 0.032
mitochondrion organization GO:0007005 4 0.032
positive regulation of catabolic process GO:0009896 4 0.032
small molecule metabolic process GO:0044281 77 0.031
signal transduction GO:0007165 455 0.030
regulation of protein transport GO:0051223 3 0.030
positive regulation of transport GO:0051050 2 0.029
oxoacid metabolic process GO:0043436 31 0.029
single organism localization GO:1902578 225 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
female sex differentiation GO:0046660 4 0.028
protein polymerization GO:0051258 4 0.028
stem cell proliferation GO:0072089 4 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
single organism organelle organization GO:1902589 199 0.028
amine metabolic process GO:0009308 2 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.027
response to drug GO:0042493 3 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.027
gene expression GO:0010467 252 0.027
cellular protein catabolic process GO:0044257 4 0.027
regulation of cytoplasmic transport GO:1903649 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
stem cell maintenance GO:0019827 4 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
meiotic nuclear division GO:0007126 4 0.025
phagocytosis GO:0006909 3 0.025
lipid storage GO:0019915 1 0.025
regulation of biological quality GO:0065008 263 0.025
microtubule organizing center organization GO:0031023 1 0.025
regulation of carbohydrate metabolic process GO:0006109 4 0.025
membrane fusion GO:0061025 2 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
organic acid metabolic process GO:0006082 31 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
protein import GO:0017038 3 0.024
single organism metabolic process GO:0044710 217 0.024
cellular amide metabolic process GO:0043603 4 0.024
cell aging GO:0007569 2 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
rna biosynthetic process GO:0032774 181 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
response to nutrient GO:0007584 3 0.023
establishment of protein localization to plasma membrane GO:0090002 1 0.023
positive regulation of map kinase activity GO:0043406 3 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
regulation of protein catabolic process GO:0042176 1 0.023
nuclear transport GO:0051169 4 0.023
proteasomal protein catabolic process GO:0010498 2 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
leukocyte proliferation GO:0070661 1 0.022
protein acetylation GO:0006473 2 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
positive regulation of cell cycle GO:0045787 3 0.022
immune system process GO:0002376 241 0.022
protein acylation GO:0043543 3 0.022
negative regulation of nuclear division GO:0051784 3 0.021
negative regulation of protein complex assembly GO:0031333 1 0.021
gtp catabolic process GO:0006184 2 0.021
regulation of transcription dna templated GO:0006355 213 0.021
homeostatic process GO:0042592 142 0.021
regulation of reproductive process GO:2000241 4 0.021
cellular component morphogenesis GO:0032989 336 0.021
atp catabolic process GO:0006200 4 0.021
regulation of intracellular protein transport GO:0033157 3 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of protein complex assembly GO:0043254 3 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
regulation of binding GO:0051098 3 0.020
activation of mapk activity GO:0000187 3 0.020
female gonad development GO:0008585 4 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
meiotic cell cycle process GO:1903046 3 0.020
cellular ketone metabolic process GO:0042180 11 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
cellular amine metabolic process GO:0044106 2 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
cellular component movement GO:0006928 335 0.019
spermatid development GO:0007286 2 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
meiotic chromosome segregation GO:0045132 3 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
multicellular organismal signaling GO:0035637 22 0.019
single organism transport GO:0044765 206 0.019
centrosome organization GO:0051297 1 0.018
ion transport GO:0006811 114 0.018
regulation of blood pressure GO:0008217 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
organelle fusion GO:0048284 3 0.018
cellular biosynthetic process GO:0044249 286 0.018
regulation of gene expression GO:0010468 265 0.018
gland development GO:0048732 143 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
positive regulation of cytokine production GO:0001819 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
transport GO:0006810 220 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
hemopoiesis GO:0030097 183 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
secondary metabolic process GO:0019748 3 0.017
regulation of gtpase activity GO:0043087 2 0.017
cell part morphogenesis GO:0032990 246 0.017
protein stabilization GO:0050821 2 0.017
regulation of oocyte development GO:0060281 3 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
regulation of hormone secretion GO:0046883 2 0.017
mitotic cytokinesis GO:0000281 3 0.017
regulation of cell shape GO:0008360 1 0.017
regulation of rho protein signal transduction GO:0035023 2 0.017
positive regulation of secretion GO:0051047 1 0.017
nuclear import GO:0051170 3 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.016
spindle assembly GO:0051225 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
single organism membrane fusion GO:0044801 2 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
muscle cell differentiation GO:0042692 139 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
protein localization to plasma membrane GO:0072659 1 0.016
sequestering of metal ion GO:0051238 3 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
rna localization GO:0006403 4 0.016
renal tubule morphogenesis GO:0061333 1 0.016
spermatid differentiation GO:0048515 2 0.016
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.016
negative regulation of mitosis GO:0045839 3 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
mitochondrial transport GO:0006839 2 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
homeostasis of number of cells GO:0048872 62 0.016
nucleic acid metabolic process GO:0090304 244 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
response to topologically incorrect protein GO:0035966 2 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
cytokinesis GO:0000910 3 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
regulation of muscle contraction GO:0006937 3 0.016
regulation of protein targeting GO:1903533 2 0.016
heart development GO:0007507 313 0.016
regulation of cell activation GO:0050865 1 0.015
autophagy GO:0006914 4 0.015
regulation of primary metabolic process GO:0080090 311 0.015
regulation of metal ion transport GO:0010959 4 0.015
mononuclear cell proliferation GO:0032943 1 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
muscle structure development GO:0061061 196 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
embryonic organ development GO:0048568 381 0.015
regulation of blood vessel size GO:0050880 2 0.015
germ line stem cell maintenance GO:0030718 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
neuroblast proliferation GO:0007405 2 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
organic substance biosynthetic process GO:1901576 289 0.015
adult behavior GO:0030534 2 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
regulation of organelle assembly GO:1902115 4 0.014
single organism nuclear import GO:1902593 3 0.014
protein localization to nucleus GO:0034504 3 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
b cell activation GO:0042113 2 0.014
protein import into nucleus GO:0006606 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
regulation of tube size GO:0035150 2 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.014
smooth muscle contraction GO:0006939 2 0.014
positive regulation of translation GO:0045727 1 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
response to chemical GO:0042221 320 0.014
rna transport GO:0050658 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
nitric oxide metabolic process GO:0046209 2 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of intracellular ph GO:0051453 1 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
cellular transition metal ion homeostasis GO:0046916 3 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
developmental programmed cell death GO:0010623 4 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
b cell differentiation GO:0030183 1 0.013
response to uv GO:0009411 3 0.013
rna metabolic process GO:0016070 219 0.013
striated muscle cell differentiation GO:0051146 129 0.013
localization of cell GO:0051674 244 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
nuclear export GO:0051168 1 0.013
cellular response to nutrient levels GO:0031669 2 0.013
determination of bilateral symmetry GO:0009855 204 0.013
circulatory system process GO:0003013 87 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
biosynthetic process GO:0009058 294 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
carbohydrate homeostasis GO:0033500 1 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
regulation of wound healing GO:0061041 2 0.013
regulation of developmental process GO:0050793 247 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
centrosome cycle GO:0007098 1 0.013
response to wounding GO:0009611 116 0.013
neuronal action potential GO:0019228 18 0.013
response to external stimulus GO:0009605 264 0.013
Zebrafish
cell morphogenesis GO:0000902 289 0.013
transmission of nerve impulse GO:0019226 19 0.013
cellular component biogenesis GO:0044085 178 0.013
transmembrane transport GO:0055085 120 0.013
oocyte maturation GO:0001556 4 0.013
tissue remodeling GO:0048771 4 0.013
adherens junction organization GO:0034332 4 0.013
pole plasm assembly GO:0007315 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of protein binding GO:0043393 3 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
neuron differentiation GO:0030182 353 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
wound healing GO:0042060 90 0.012
blood circulation GO:0008015 87 0.012
regulation of cell communication GO:0010646 232 0.012
cellular component disassembly GO:0022411 1 0.012
cell projection organization GO:0030030 284 0.012
organelle organization GO:0006996 227 0.012
growth GO:0040007 174 0.012
cytoskeleton organization GO:0007010 96 0.012
intracellular mrna localization GO:0008298 1 0.012
cell cycle arrest GO:0007050 1 0.012
nephron morphogenesis GO:0072028 2 0.012
meiotic spindle organization GO:0000212 1 0.012
meiosis i GO:0007127 1 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
glucose homeostasis GO:0042593 1 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
cellular response to starvation GO:0009267 1 0.012
myeloid cell homeostasis GO:0002262 56 0.012
response to fluid shear stress GO:0034405 2 0.012
locomotion GO:0040011 313 0.012
response to organic substance GO:0010033 153 0.012
hormone transport GO:0009914 2 0.012
cell matrix adhesion GO:0007160 4 0.012
lateral inhibition GO:0046331 1 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
regulation of transporter activity GO:0032409 2 0.012
positive regulation of neuron death GO:1901216 1 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
regulation of rna metabolic process GO:0051252 224 0.012
regulation of metabolic process GO:0019222 359 0.012
protein metabolic process GO:0019538 183 0.012
microtubule based process GO:0007017 60 0.012
immune system development GO:0002520 191 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
cellular component assembly GO:0022607 170 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
regulation of autophagy GO:0010506 3 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
nucleic acid transport GO:0050657 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
negative regulation of kinase activity GO:0033673 4 0.012
telomere maintenance GO:0000723 1 0.012
cytoplasm organization GO:0007028 4 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
regulation of localization GO:0032879 104 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
compound eye development GO:0048749 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
peptide metabolic process GO:0006518 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
heart process GO:0003015 71 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of cellular ph GO:0030641 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
membrane invagination GO:0010324 1 0.011
protein complex localization GO:0031503 1 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
specification of symmetry GO:0009799 204 0.011
locomotor rhythm GO:0045475 3 0.011
protein secretion GO:0009306 1 0.011
nucleobase containing compound transport GO:0015931 2 0.011
head development GO:0060322 303 0.011
action potential GO:0001508 19 0.011
muscle cell development GO:0055001 115 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
establishment of rna localization GO:0051236 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
actin filament polymerization GO:0030041 2 0.011
response to vitamin GO:0033273 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
hepaticobiliary system development GO:0061008 98 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
regulation of signal transduction GO:0009966 225 0.011
lymphocyte proliferation GO:0046651 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
apoptotic process involved in development GO:1902742 2 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of chromosome segregation GO:0051983 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
oxidative phosphorylation GO:0006119 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
peptidyl serine modification GO:0018209 2 0.011
negative regulation of biological process GO:0048519 304 0.011
peptide transport GO:0015833 1 0.011
hormone secretion GO:0046879 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
multi organism cellular process GO:0044764 2 0.010
carbohydrate derivative metabolic process GO:1901135 61 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
determination of left right symmetry GO:0007368 179 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010
negative regulation of cellular process GO:0048523 283 0.010
regulation of response to stimulus GO:0048583 269 0.010
regulation of protein polymerization GO:0032271 2 0.010
regulation of jun kinase activity GO:0043506 3 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
regulation of jak stat cascade GO:0046425 3 0.010
regulation of biosynthetic process GO:0009889 250 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
sensory organ development GO:0007423 393 0.010
lipid digestion GO:0044241 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
centrosome duplication GO:0051298 1 0.010
cell projection morphogenesis GO:0048858 244 0.010
energy reserve metabolic process GO:0006112 2 0.010
striated muscle cell development GO:0055002 108 0.010
cellular localization GO:0051641 97 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
positive regulation of signal transduction GO:0009967 56 0.010
cell migration GO:0016477 237 0.010

dia1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
musculoskeletal system disease DOID:17 0 0.015
organ system cancer DOID:0050686 0 0.013
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
sensory system disease DOID:0050155 0 0.010