Danio rerio

99 known processes

ryk

receptor-like tyrosine kinase

(Aliases: zgc:158381,wu:fi05b06,wu:fb37b12)

ryk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.626
convergent extension involved in gastrulation GO:0060027 71 0.601
regulation of signaling GO:0023051 235 0.515
Human
tube morphogenesis GO:0035239 349 0.510
cognition GO:0050890 1 0.481
Fly
negative regulation of cellular process GO:0048523 283 0.452
morphogenesis of an epithelium GO:0002009 333 0.414
digestive tract development GO:0048565 265 0.372
negative regulation of biological process GO:0048519 304 0.356
heart development GO:0007507 313 0.354
digestive system development GO:0055123 289 0.334
cellular component morphogenesis GO:0032989 336 0.331
Mouse Fly
signal transduction GO:0007165 455 0.317
regulation of cell communication GO:0010646 232 0.294
Human
embryonic organ development GO:0048568 381 0.288
cell surface receptor signaling pathway GO:0007166 325 0.279
extrinsic apoptotic signaling pathway GO:0097191 3 0.276
endocardial cushion development GO:0003197 6 0.271
immune system development GO:0002520 191 0.259
regulation of transcription dna templated GO:0006355 213 0.256
stem cell maintenance GO:0019827 4 0.240
regulation of stem cell differentiation GO:2000736 4 0.240
muscle structure development GO:0061061 196 0.229
Fly
generation of neurons GO:0048699 385 0.226
Mouse Fly
somitogenesis GO:0001756 87 0.225
modification dependent protein catabolic process GO:0019941 3 0.216
response to external stimulus GO:0009605 264 0.212
Mouse Fly
regulation of signal transduction GO:0009966 225 0.211
Human
regulation of developmental process GO:0050793 247 0.209
Mouse Worm
hemopoiesis GO:0030097 183 0.204
organelle organization GO:0006996 227 0.202
chordate embryonic development GO:0043009 271 0.200
regulation of anatomical structure morphogenesis GO:0022603 130 0.196
Mouse
regulation of metabolic process GO:0019222 359 0.194
Human
single organism organelle organization GO:1902589 199 0.191
transcription dna templated GO:0006351 181 0.182
nucleic acid metabolic process GO:0090304 244 0.181
regulation of multicellular organismal development GO:2000026 223 0.177
Mouse Worm
response to chemical GO:0042221 320 0.175
Mouse Fly
positive regulation of signaling GO:0023056 56 0.175
Human
negative regulation of wnt signaling pathway GO:0030178 30 0.173
regulation of cell shape GO:0008360 1 0.172
heart morphogenesis GO:0003007 156 0.170
regulation of response to stimulus GO:0048583 269 0.168
Human Mouse
system process GO:0003008 185 0.167
Fly
cell death GO:0008219 121 0.166
maintenance of location GO:0051235 4 0.161
organic cyclic compound biosynthetic process GO:1901362 223 0.159
developmental growth GO:0048589 166 0.157
regulation of nucleic acid templated transcription GO:1903506 213 0.152
determination of left right symmetry GO:0007368 179 0.152
blood vessel development GO:0001568 246 0.151
transport GO:0006810 220 0.151
positive regulation of cell cycle GO:0045787 3 0.151
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.147
endocardial cushion formation GO:0003272 2 0.145
determination of bilateral symmetry GO:0009855 204 0.144
urogenital system development GO:0001655 97 0.142
specification of symmetry GO:0009799 204 0.141
cellular component movement GO:0006928 335 0.140
segment polarity determination GO:0007367 1 0.138
periodic partitioning GO:0007365 1 0.137
hematopoietic or lymphoid organ development GO:0048534 191 0.137
segmentation GO:0035282 97 0.134
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.134
regulation of cellular metabolic process GO:0031323 320 0.133
Human
epithelial cell morphogenesis GO:0003382 2 0.129
nucleobase containing compound metabolic process GO:0006139 274 0.129
embryonic limb morphogenesis GO:0030326 2 0.129
larval development GO:0002164 2 0.127
Worm
neuron projection morphogenesis GO:0048812 161 0.124
Mouse Fly
neuron differentiation GO:0030182 353 0.122
Mouse Fly
cell morphogenesis GO:0000902 289 0.121
Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.121
localization of cell GO:0051674 244 0.118
embryonic heart tube development GO:0035050 133 0.117
positive regulation of rna metabolic process GO:0051254 59 0.116
stem cell division GO:0017145 1 0.115
biosynthetic process GO:0009058 294 0.114
negative regulation of response to stimulus GO:0048585 104 0.113
Mouse
somite development GO:0061053 96 0.112
cellular macromolecule metabolic process GO:0044260 391 0.111
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.107
modification dependent macromolecule catabolic process GO:0043632 3 0.106
regulation of glial cell differentiation GO:0045685 4 0.105
cell part morphogenesis GO:0032990 246 0.104
Mouse Fly
gland development GO:0048732 143 0.103
Fly
regulation of rna biosynthetic process GO:2001141 213 0.103
muscle cell differentiation GO:0042692 139 0.102
primary neural tube formation GO:0014020 1 0.101
regulation of macromolecule metabolic process GO:0060255 317 0.099
negative regulation of multicellular organismal process GO:0051241 69 0.099
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.099
endothelial cell fate commitment GO:0060839 3 0.097
sensory perception GO:0007600 39 0.097
neurological system process GO:0050877 62 0.097
Fly
central nervous system development GO:0007417 387 0.096
Mouse
sensory perception of chemical stimulus GO:0007606 3 0.096
cellular nitrogen compound metabolic process GO:0034641 290 0.096
nitrogen compound metabolic process GO:0006807 319 0.095
cellular macromolecule biosynthetic process GO:0034645 224 0.095
protein secretion GO:0009306 1 0.095
regulation of macromolecule biosynthetic process GO:0010556 225 0.094
macromolecule biosynthetic process GO:0009059 227 0.094
cellular response to growth factor stimulus GO:0071363 39 0.094
vasculature development GO:0001944 278 0.093
cell matrix adhesion GO:0007160 4 0.092
positive regulation of response to stimulus GO:0048584 80 0.091
Human
rna metabolic process GO:0016070 219 0.091
phosphorus metabolic process GO:0006793 109 0.091
Human Fly
rna biosynthetic process GO:0032774 181 0.090
macromolecule modification GO:0043412 111 0.089
Fly
embryonic organ morphogenesis GO:0048562 274 0.089
wnt signaling pathway GO:0016055 80 0.089
positive regulation of map kinase activity GO:0043406 3 0.089
lipid storage GO:0019915 1 0.088
protein metabolic process GO:0019538 183 0.088
Fly
cellular component assembly GO:0022607 170 0.088
response to stress GO:0006950 263 0.088
brain development GO:0007420 293 0.087
Mouse
myeloid cell differentiation GO:0030099 86 0.087
aging GO:0007568 2 0.087
positive regulation of metabolic process GO:0009893 108 0.087
Human
regulation of phosphorus metabolic process GO:0051174 43 0.086
Human
forebrain cell migration GO:0021885 1 0.084
head development GO:0060322 303 0.082
Mouse
negative regulation of cell death GO:0060548 60 0.082
positive regulation of cell communication GO:0010647 56 0.082
Human
forebrain development GO:0030900 96 0.081
Mouse
sprouting angiogenesis GO:0002040 53 0.081
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.081
intracellular signal transduction GO:0035556 85 0.080
Human
single organism nuclear import GO:1902593 3 0.079
somatic stem cell maintenance GO:0035019 1 0.079
heterocycle biosynthetic process GO:0018130 215 0.078
cellular ketone metabolic process GO:0042180 11 0.078
muscle cell migration GO:0014812 4 0.077
tube closure GO:0060606 1 0.076
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.076
regulation of establishment of protein localization GO:0070201 4 0.075
regulation of cellular biosynthetic process GO:0031326 245 0.075
positive regulation of biological process GO:0048518 253 0.074
Human
oxoacid metabolic process GO:0043436 31 0.074
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.074
wound healing GO:0042060 90 0.074
regulation of protein transport GO:0051223 3 0.074
cell fate commitment GO:0045165 99 0.073
Worm Fly
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.073
regulation of apoptotic process GO:0042981 98 0.073
heterocycle metabolic process GO:0046483 290 0.072
regulation of receptor activity GO:0010469 2 0.072
regulation of wnt signaling pathway GO:0030111 53 0.071
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.071
epithelial cell differentiation GO:0030855 116 0.071
neuron development GO:0048666 262 0.071
Mouse Fly
adherens junction organization GO:0034332 4 0.071
renal system development GO:0072001 94 0.071
cell proliferation GO:0008283 80 0.071
single organism behavior GO:0044708 24 0.070
Fly
olfactory bulb development GO:0021772 4 0.070
positive regulation of cellular biosynthetic process GO:0031328 68 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.070
negative regulation of signal transduction GO:0009968 94 0.069
gene expression GO:0010467 252 0.069
canonical wnt signaling pathway GO:0060070 48 0.069
sensory organ development GO:0007423 393 0.069
multicellular organism growth GO:0035264 4 0.068
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.068
regulation of gene expression GO:0010468 265 0.068
regulation of biosynthetic process GO:0009889 250 0.068
positive regulation of multicellular organismal process GO:0051240 52 0.067
regulation of cell death GO:0010941 103 0.067
regulation of cell differentiation GO:0045595 142 0.067
Mouse
locomotion GO:0040011 313 0.066
response to organic substance GO:0010033 153 0.065
nucleobase containing compound biosynthetic process GO:0034654 205 0.065
cell substrate adhesion GO:0031589 4 0.065
death GO:0016265 121 0.064
regulation of protein binding GO:0043393 3 0.064
endocardial cushion morphogenesis GO:0003203 3 0.064
aromatic compound biosynthetic process GO:0019438 217 0.064
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.064
stem cell proliferation GO:0072089 4 0.063
positive regulation of signal transduction GO:0009967 56 0.063
Human
phosphate containing compound metabolic process GO:0006796 108 0.063
Human Fly
cell projection organization GO:0030030 284 0.063
Mouse Fly
b cell differentiation GO:0030183 1 0.062
immune system process GO:0002376 241 0.062
centrosome cycle GO:0007098 1 0.061
behavior GO:0007610 74 0.061
Mouse Fly
negative regulation of gene expression GO:0010629 65 0.061
response to virus GO:0009615 21 0.060
protein localization to nucleus GO:0034504 3 0.060
cell projection morphogenesis GO:0048858 244 0.059
Mouse Fly
regulation of phosphate metabolic process GO:0019220 43 0.059
Human
regulation of multicellular organismal process GO:0051239 277 0.059
Mouse Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.058
b cell activation GO:0042113 2 0.058
single organism localization GO:1902578 225 0.057
positive regulation of rna biosynthetic process GO:1902680 57 0.057
ameboidal type cell migration GO:0001667 143 0.057
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.057
cellular protein modification process GO:0006464 100 0.057
Fly
kidney development GO:0001822 92 0.056
synaptic target recognition GO:0008039 1 0.056
Fly
regulation of cell activation GO:0050865 1 0.056
nucleic acid templated transcription GO:0097659 181 0.056
regulation of rho protein signal transduction GO:0035023 2 0.056
striated muscle cell differentiation GO:0051146 129 0.056
post embryonic organ development GO:0048569 4 0.055
Worm
regulation of cellular component organization GO:0051128 86 0.055
Mouse
small molecule metabolic process GO:0044281 77 0.055
chemosensory behavior GO:0007635 1 0.054
Fly
synaptic vesicle localization GO:0097479 1 0.054
neural tube patterning GO:0021532 33 0.054
regulation of locomotion GO:0040012 55 0.054
Mouse
protein import into nucleus GO:0006606 3 0.054
adult behavior GO:0030534 2 0.054
establishment of protein localization to organelle GO:0072594 4 0.054
microtubule organizing center organization GO:0031023 1 0.053
nucleocytoplasmic transport GO:0006913 4 0.053
determination of heart left right asymmetry GO:0061371 117 0.053
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
regulation of blood vessel size GO:0050880 2 0.053
erk1 and erk2 cascade GO:0070371 4 0.053
cell migration GO:0016477 237 0.053
apoptotic process GO:0006915 116 0.052
angiogenesis GO:0001525 158 0.052
sensory perception of mechanical stimulus GO:0050954 16 0.052
regulation of rna metabolic process GO:0051252 224 0.052
regulation of axonogenesis GO:0050770 32 0.052
Mouse
leukocyte differentiation GO:0002521 25 0.051
cellular carbohydrate metabolic process GO:0044262 4 0.051
heart looping GO:0001947 94 0.051
hepaticobiliary system development GO:0061008 98 0.051
gastrulation GO:0007369 208 0.051
organic acid metabolic process GO:0006082 31 0.051
positive regulation of epithelial cell proliferation GO:0050679 1 0.050
regulation of biological quality GO:0065008 263 0.050
regulation of cellular ketone metabolic process GO:0010565 7 0.050
regulation of oocyte development GO:0060281 3 0.050
negative regulation of cell communication GO:0010648 96 0.049
myeloid leukocyte differentiation GO:0002573 15 0.049
cellular response to chemical stimulus GO:0070887 157 0.049
negative regulation of protein kinase activity GO:0006469 4 0.049
regulation of cell morphogenesis GO:0022604 42 0.049
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.049
negative regulation of protein transport GO:0051224 3 0.048
regulation of organ morphogenesis GO:2000027 35 0.048
regulation of establishment of planar polarity GO:0090175 4 0.048
establishment of localization in cell GO:0051649 77 0.048
negative chemotaxis GO:0050919 1 0.048
Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.048
cellular component biogenesis GO:0044085 178 0.047
fin regeneration GO:0031101 51 0.047
positive regulation of cell adhesion GO:0045785 1 0.046
hypothalamus cell differentiation GO:0021979 4 0.046
enzyme linked receptor protein signaling pathway GO:0007167 106 0.046
regulation of mesoderm development GO:2000380 11 0.046
dorsal ventral pattern formation GO:0009953 125 0.045
regulation of cellular amino acid metabolic process GO:0006521 0 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.045
regulation of organ growth GO:0046620 3 0.044
negative regulation of nucleic acid templated transcription GO:1903507 45 0.044
programmed cell death GO:0012501 119 0.044
cell activation GO:0001775 16 0.044
positive regulation of transcription dna templated GO:0045893 57 0.044
regulation of programmed cell death GO:0043067 101 0.044
eye development GO:0001654 277 0.043
response to endogenous stimulus GO:0009719 83 0.043
blood vessel morphogenesis GO:0048514 216 0.043
cellular response to organic substance GO:0071310 105 0.043
embryonic heart tube morphogenesis GO:0003143 108 0.043
regulation of cell motility GO:2000145 46 0.042
axon extension GO:0048675 45 0.042
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.041
Mouse
regulation of response to nutrient levels GO:0032107 1 0.041
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.041
cellular biosynthetic process GO:0044249 286 0.041
negative regulation of signaling GO:0023057 96 0.041
positive regulation of catabolic process GO:0009896 4 0.041
small gtpase mediated signal transduction GO:0007264 8 0.041
establishment of localization GO:0051234 244 0.040
protein targeting to nucleus GO:0044744 3 0.040
transcription from rna polymerase ii promoter GO:0006366 80 0.040
hemostasis GO:0007599 13 0.039
positive regulation of stress activated mapk cascade GO:0032874 3 0.039
synaptic growth at neuromuscular junction GO:0051124 2 0.039
regionalization GO:0003002 274 0.039
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.039
Mouse Fly
pronephros development GO:0048793 69 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.038
positive regulation of nucleic acid templated transcription GO:1903508 57 0.038
organic substance biosynthetic process GO:1901576 289 0.038
positive regulation of apoptotic signaling pathway GO:2001235 1 0.038
regulation of dna replication GO:0006275 3 0.038
epithelial cell development GO:0002064 42 0.038
cytoskeleton organization GO:0007010 96 0.037
regulation of apoptotic signaling pathway GO:2001233 12 0.037
regulation of gtp catabolic process GO:0033124 2 0.037
regulation of cytoplasmic transport GO:1903649 4 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.037
regulation of catalytic activity GO:0050790 55 0.037
organonitrogen compound metabolic process GO:1901564 74 0.037
taxis GO:0042330 109 0.037
Mouse Fly
olfactory lobe development GO:0021988 4 0.036
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.036
cellular response to external stimulus GO:0071496 2 0.036
regulation of response to oxidative stress GO:1902882 2 0.036
cardiac cell fate commitment GO:0060911 1 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
negative regulation of secretion GO:0051048 2 0.035
regulation of cell development GO:0060284 100 0.035
Mouse
neural tube development GO:0021915 62 0.035
specification of organ identity GO:0010092 2 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
embryo development ending in birth or egg hatching GO:0009792 271 0.035
organic cyclic compound metabolic process GO:1901360 301 0.035
specification of axis polarity GO:0065001 4 0.035
Worm
regulation of nervous system development GO:0051960 90 0.035
Mouse
cartilage development GO:0051216 96 0.035
regulation of molecular function GO:0065009 70 0.034
regulation of reproductive process GO:2000241 4 0.034
regulation of tube size GO:0035150 2 0.034
positive regulation of gtp catabolic process GO:0033126 1 0.034
negative regulation of epithelial cell proliferation GO:0050680 1 0.034
nephron development GO:0072006 31 0.034
cellular amino acid metabolic process GO:0006520 7 0.033
peptidyl serine modification GO:0018209 2 0.033
gastrulation with mouth forming second GO:0001702 44 0.033
negative regulation of nervous system development GO:0051961 22 0.033
Mouse
pharyngeal muscle development GO:0043282 4 0.033
negative regulation of transcription dna templated GO:0045892 45 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
positive regulation of cytokine production GO:0001819 2 0.033
developmental growth involved in morphogenesis GO:0060560 86 0.033
liver development GO:0001889 96 0.033
neuroblast proliferation GO:0007405 2 0.033
exocrine system development GO:0035272 28 0.032
Fly
homeostatic process GO:0042592 142 0.032
telencephalon development GO:0021537 14 0.032
Mouse
regulation of cell matrix adhesion GO:0001952 1 0.032
cell adhesion GO:0007155 40 0.032
osteoclast differentiation GO:0030316 1 0.032
neural tube formation GO:0001841 16 0.032
proteasomal protein catabolic process GO:0010498 2 0.032
tissue regeneration GO:0042246 74 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
epithelial tube morphogenesis GO:0060562 148 0.031
positive regulation of transport GO:0051050 2 0.031
biological adhesion GO:0022610 40 0.031
protein modification process GO:0036211 100 0.030
Fly
negative regulation of gliogenesis GO:0014014 1 0.030
anterior posterior pattern specification GO:0009952 152 0.030
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.030
Mouse Fly
gland morphogenesis GO:0022612 13 0.030
Fly
response to nutrient GO:0007584 3 0.030
cellular response to extracellular stimulus GO:0031668 2 0.030
regulation of cytokine production GO:0001817 3 0.030
negative regulation of programmed cell death GO:0043069 58 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.030
negative regulation of apoptotic process GO:0043066 55 0.030
regulation of lipase activity GO:0060191 2 0.030
leukocyte activation GO:0045321 12 0.029
coagulation GO:0050817 13 0.029
centrosome organization GO:0051297 1 0.029
regulation of protein catabolic process GO:0042176 1 0.029
stem cell development GO:0048864 82 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.029
nuclear transport GO:0051169 4 0.029
cell migration involved in gastrulation GO:0042074 79 0.029
anatomical structure homeostasis GO:0060249 36 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
negative regulation of cell differentiation GO:0045596 46 0.028
Mouse
response to growth factor GO:0070848 39 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
regulation of cellular response to growth factor stimulus GO:0090287 35 0.028
response to alkaloid GO:0043279 2 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.028
aorta development GO:0035904 4 0.028
regulation of chondrocyte differentiation GO:0032330 1 0.027
positive regulation of leukocyte differentiation GO:1902107 1 0.027
negative regulation of dna replication GO:0008156 2 0.027
regulation of cell proliferation GO:0042127 37 0.027
cellular modified amino acid metabolic process GO:0006575 3 0.027
axonogenesis GO:0007409 152 0.027
Mouse Fly
cellular response to radiation GO:0071478 4 0.027
convergent extension GO:0060026 118 0.027
positive regulation of cellular process GO:0048522 201 0.027
Human
regulation of biomineral tissue development GO:0070167 2 0.027
rho protein signal transduction GO:0007266 5 0.027
regulation of embryonic development GO:0045995 47 0.027
single organism transport GO:0044765 206 0.027
macromolecule localization GO:0033036 54 0.026
Worm
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.026
positive regulation of gene expression GO:0010628 71 0.026
cellular protein catabolic process GO:0044257 4 0.026
actin filament based movement GO:0030048 1 0.026
cellular response to endogenous stimulus GO:0071495 68 0.026
mesenchymal cell differentiation GO:0048762 87 0.026
positive regulation of immune system process GO:0002684 17 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
positive regulation of stem cell proliferation GO:2000648 1 0.026
growth GO:0040007 174 0.026
stem cell differentiation GO:0048863 117 0.026
mesodermal cell differentiation GO:0048333 21 0.026
ras protein signal transduction GO:0007265 7 0.026
response to wounding GO:0009611 116 0.026
regulation of cell fate commitment GO:0010453 22 0.025
mitotic cell cycle process GO:1903047 48 0.025
homeostasis of number of cells within a tissue GO:0048873 4 0.025
glomerular filtration GO:0003094 6 0.025
smooth muscle contraction GO:0006939 2 0.025
regulation of mesenchymal cell proliferation GO:0010464 1 0.025
regulation of cell cell adhesion GO:0022407 13 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.025
i kappab kinase nf kappab signaling GO:0007249 4 0.025
muscle organ development GO:0007517 101 0.025
Fly
organic substance transport GO:0071702 58 0.025
lateral line system development GO:0048925 76 0.025
lateral inhibition GO:0046331 1 0.024
Fly
nerve development GO:0021675 45 0.024
meiosis i GO:0007127 1 0.024
mesoderm development GO:0007498 88 0.024
mesodermal cell fate commitment GO:0001710 14 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
cellular amine metabolic process GO:0044106 2 0.024
synaptic vesicle transport GO:0048489 1 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
negative regulation of protein metabolic process GO:0051248 16 0.024
central nervous system neuron differentiation GO:0021953 74 0.024
response to biotic stimulus GO:0009607 97 0.024
regulation of cell substrate adhesion GO:0010810 1 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
regulation of cellular protein catabolic process GO:1903362 1 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
negative regulation of stem cell differentiation GO:2000737 2 0.023
apoptotic signaling pathway GO:0097190 23 0.023
regulation of heart growth GO:0060420 2 0.023
germ line stem cell division GO:0042078 1 0.023
positive regulation of apoptotic process GO:0043065 29 0.023
dorsal ventral neural tube patterning GO:0021904 1 0.023
positive regulation of myeloid cell differentiation GO:0045639 2 0.023
regulation of proteolysis GO:0030162 24 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
response to radiation GO:0009314 51 0.022
leukocyte mediated cytotoxicity GO:0001909 1 0.022
phagocytosis GO:0006909 3 0.022
skeletal system morphogenesis GO:0048705 102 0.022
Mouse
muscle cell development GO:0055001 115 0.022
neuromast deposition GO:0048885 9 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
hematopoietic progenitor cell differentiation GO:0002244 23 0.022
pancreas development GO:0031016 84 0.022
peptidyl tyrosine modification GO:0018212 5 0.022
Fly
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.022
skeletal system development GO:0001501 181 0.022
Mouse
nuclear import GO:0051170 3 0.021
negative regulation of developmental process GO:0051093 65 0.021
Mouse
multi organism process GO:0051704 134 0.021
negative regulation of kinase activity GO:0033673 4 0.021
cranial nerve morphogenesis GO:0021602 15 0.021
regulation of synapse assembly GO:0051963 3 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.021
phosphorylation GO:0016310 69 0.021
Human Fly
positive regulation of notch signaling pathway GO:0045747 3 0.021
cranial nerve development GO:0021545 42 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
proximal distal pattern formation GO:0009954 1 0.021
Worm
morphogenesis of an epithelial sheet GO:0002011 49 0.021
regulation of phospholipase c activity GO:1900274 1 0.021
negative regulation of feeding behavior GO:2000252 2 0.021
negative regulation of secretion by cell GO:1903531 2 0.021
positive regulation of leukocyte mediated immunity GO:0002705 1 0.021
regulation of protein metabolic process GO:0051246 56 0.021
actin mediated cell contraction GO:0070252 1 0.021
arterial endothelial cell differentiation GO:0060842 2 0.021
mononuclear cell proliferation GO:0032943 1 0.021
regulation of mesodermal cell fate specification GO:0042661 9 0.021
negative regulation of catabolic process GO:0009895 3 0.020
signal transduction by phosphorylation GO:0023014 18 0.020
Human
endodermal cell fate determination GO:0007493 2 0.020
regulation of gtpase activity GO:0043087 2 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
germ line stem cell maintenance GO:0030718 2 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
mesenchymal cell proliferation GO:0010463 1 0.020
lymphocyte activation GO:0046649 10 0.020
paraxial mesoderm morphogenesis GO:0048340 2 0.020
negative regulation of synapse assembly GO:0051964 2 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
outflow tract morphogenesis GO:0003151 1 0.020
bmp signaling pathway GO:0030509 52 0.020

ryk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
organ system cancer DOID:0050686 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
cancer DOID:162 0 0.034