Danio rerio

78 known processes

gnb2l1

guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1

(Aliases: wu:fb80d08,wu:fk65d12,rack1)

gnb2l1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular biosynthetic process GO:0044249 286 0.848
Yeast Rat Fly
larval development GO:0002164 2 0.783
Worm
programmed cell death GO:0012501 119 0.629
Human
death GO:0016265 121 0.624
Human Mouse
single organism organelle organization GO:1902589 199 0.441
regulation of cellular biosynthetic process GO:0031326 245 0.381
Yeast Rat Fly
immune system process GO:0002376 241 0.368
cell death GO:0008219 121 0.353
Human Mouse
microtubule organizing center organization GO:0031023 1 0.348
biosynthetic process GO:0009058 294 0.342
Yeast Rat Fly
centrosome organization GO:0051297 1 0.341
gene expression GO:0010467 252 0.340
Human Yeast Rat
organic substance biosynthetic process GO:1901576 289 0.325
Yeast Rat Fly
cellular macromolecule metabolic process GO:0044260 391 0.300
Human Yeast Rat Fly
cell cycle process GO:0022402 53 0.277
Worm
generation of neurons GO:0048699 385 0.260
Worm
macromolecule biosynthetic process GO:0009059 227 0.252
Yeast Rat Fly
microtubule based process GO:0007017 60 0.251
organic cyclic compound metabolic process GO:1901360 301 0.228
Human Yeast
apoptotic process GO:0006915 116 0.224
Human
nucleic acid metabolic process GO:0090304 244 0.215
regulation of biological quality GO:0065008 263 0.214
Human Yeast Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.205
Human Yeast
centrosome duplication GO:0051298 1 0.203
organelle organization GO:0006996 227 0.203
Worm
chordate embryonic development GO:0043009 271 0.198
cellular aromatic compound metabolic process GO:0006725 295 0.193
Human Yeast
regulation of gene expression GO:0010468 265 0.192
Human Yeast Rat
somite development GO:0061053 96 0.183
heterocycle biosynthetic process GO:0018130 215 0.182
response to chemical GO:0042221 320 0.178
Human Yeast Mouse Worm
aging GO:0007568 2 0.178
negative regulation of response to stimulus GO:0048585 104 0.175
heterocycle metabolic process GO:0046483 290 0.172
Human Yeast
tube morphogenesis GO:0035239 349 0.169
sexual reproduction GO:0019953 36 0.169
Fly
mitotic cell cycle GO:0000278 64 0.168
Worm
digestive tract morphogenesis GO:0048546 231 0.165
regulation of apoptotic process GO:0042981 98 0.164
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.152
Yeast Rat Fly
mitotic cell cycle process GO:1903047 48 0.151
Worm
positive regulation of apoptotic signaling pathway GO:2001235 1 0.145
Human
digestive tract development GO:0048565 265 0.143
signal transduction GO:0007165 455 0.143
nitrogen compound metabolic process GO:0006807 319 0.133
Human Yeast
cell cycle GO:0007049 93 0.132
Human Worm
regulation of primary metabolic process GO:0080090 311 0.131
Human Yeast Rat Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.130
Worm
mitotic spindle organization GO:0007052 5 0.129
regulation of cellular metabolic process GO:0031323 320 0.128
Human Yeast Rat Fly
regulation of macromolecule metabolic process GO:0060255 317 0.127
Human Yeast Rat Fly
transcription dna templated GO:0006351 181 0.117
digestive system development GO:0055123 289 0.114
hematopoietic or lymphoid organ development GO:0048534 191 0.111
regulation of macromolecule biosynthetic process GO:0010556 225 0.109
Yeast Rat Fly
gastrulation GO:0007369 208 0.104
nucleobase containing compound biosynthetic process GO:0034654 205 0.103
regulation of rna metabolic process GO:0051252 224 0.100
maintenance of location GO:0051235 4 0.100
hemopoiesis GO:0030097 183 0.099
homeostasis of number of cells GO:0048872 62 0.096
neuron differentiation GO:0030182 353 0.095
Worm
oogenesis GO:0048477 14 0.095
Fly
single organism transport GO:0044765 206 0.094
Human Mouse
regulation of response to stimulus GO:0048583 269 0.090
developmental growth GO:0048589 166 0.090
Worm
single fertilization GO:0007338 3 0.088
regulation of establishment of protein localization GO:0070201 4 0.088
Rat
regulation of metabolic process GO:0019222 359 0.079
Human Yeast Rat Fly
positive regulation of apoptotic process GO:0043065 29 0.079
Human
meiotic nuclear division GO:0007126 4 0.078
Worm
immune system development GO:0002520 191 0.075
response to stress GO:0006950 263 0.075
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.075
Human Yeast
positive regulation of programmed cell death GO:0043068 29 0.074
Human
somitogenesis GO:0001756 87 0.074
microtubule cytoskeleton organization GO:0000226 33 0.074
cytoskeleton organization GO:0007010 96 0.072
mitotic nuclear division GO:0007067 18 0.070
muscle structure development GO:0061061 196 0.070
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
Human
regulation of signal transduction GO:0009966 225 0.069
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.069
Human
single organism localization GO:1902578 225 0.069
Human Mouse Rat
intracellular signal transduction GO:0035556 85 0.068
Human
ribosomal small subunit biogenesis GO:0042274 2 0.068
regulation of signaling GO:0023051 235 0.067
transport GO:0006810 220 0.066
Human Mouse
apoptotic signaling pathway GO:0097190 23 0.063
Human
regulation of cell death GO:0010941 103 0.062
Human Mouse
gamete generation GO:0007276 33 0.060
Fly
ribosome assembly GO:0042255 1 0.060
segmentation GO:0035282 97 0.060
organelle assembly GO:0070925 110 0.060
nuclear division GO:0000280 23 0.059
Worm
eye development GO:0001654 277 0.058
cell cycle g1 s phase transition GO:0044843 1 0.058
germ cell development GO:0007281 22 0.058
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.054
Human
multicellular organism growth GO:0035264 4 0.054
regulation of cell cycle process GO:0010564 20 0.053
neuron death GO:0070997 21 0.053
Human Mouse
regionalization GO:0003002 274 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.052
Yeast Rat Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.052
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.051
regulation of biosynthetic process GO:0009889 250 0.050
Yeast Rat Fly
sensory organ development GO:0007423 393 0.050
regulation of multicellular organismal process GO:0051239 277 0.050
embryonic organ development GO:0048568 381 0.049
nuclear import GO:0051170 3 0.049
negative regulation of cellular process GO:0048523 283 0.049
regulation of transcription dna templated GO:0006355 213 0.049
central nervous system development GO:0007417 387 0.048
positive regulation of cellular process GO:0048522 201 0.048
Human Fly
carbohydrate derivative metabolic process GO:1901135 61 0.048
Human Yeast
positive regulation of metabolic process GO:0009893 108 0.047
Human Fly
meiotic cell cycle process GO:1903046 3 0.046
Worm
regulation of cell communication GO:0010646 232 0.046
myeloid cell differentiation GO:0030099 86 0.045
reproduction GO:0000003 40 0.045
Worm Fly
heart development GO:0007507 313 0.045
olfactory bulb development GO:0021772 4 0.044
single organism metabolic process GO:0044710 217 0.043
Human Yeast Fly
cell projection organization GO:0030030 284 0.042
Worm
lipid storage GO:0019915 1 0.042
leukocyte proliferation GO:0070661 1 0.042
positive regulation of cell cycle GO:0045787 3 0.041
positive regulation of transport GO:0051050 2 0.041
positive regulation of biological process GO:0048518 253 0.039
positive regulation of signal transduction GO:0009967 56 0.039
Human
nucleocytoplasmic transport GO:0006913 4 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
nuclear transport GO:0051169 4 0.038
rna biosynthetic process GO:0032774 181 0.037
oocyte anterior posterior axis specification GO:0007314 4 0.037
centrosome cycle GO:0007098 1 0.036
macromolecular complex subunit organization GO:0043933 74 0.036
Human
regulation of cell cycle GO:0051726 52 0.036
Human
leukocyte homeostasis GO:0001776 2 0.036
regulation of cytoplasmic transport GO:1903649 4 0.035
growth GO:0040007 174 0.035
Human Yeast Worm
response to external stimulus GO:0009605 264 0.035
Worm Fly
zymogen activation GO:0031638 3 0.034
Human
regulation of protein transport GO:0051223 3 0.034
guanosine containing compound metabolic process GO:1901068 4 0.034
Human Yeast
taxis GO:0042330 109 0.034
Worm
cell proliferation GO:0008283 80 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
Human
system process GO:0003008 185 0.033
organic substance transport GO:0071702 58 0.033
erythrocyte development GO:0048821 24 0.032
cellular component biogenesis GO:0044085 178 0.032
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.031
protein complex subunit organization GO:0071822 46 0.031
Human
regulation of developmental process GO:0050793 247 0.031
myeloid cell homeostasis GO:0002262 56 0.030
response to biotic stimulus GO:0009607 97 0.030
positive regulation of catalytic activity GO:0043085 25 0.029
Human
phagocytosis GO:0006909 3 0.029
Human
axonogenesis GO:0007409 152 0.029
Worm
pharyngeal muscle development GO:0043282 4 0.029
positive regulation of catabolic process GO:0009896 4 0.029
Human
regulation of multicellular organism growth GO:0040014 4 0.029
nucleic acid templated transcription GO:0097659 181 0.029
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
Human Yeast Rat
regulation of rna biosynthetic process GO:2001141 213 0.028
neuron projection morphogenesis GO:0048812 161 0.027
Worm
locomotion GO:0040011 313 0.027
Human Worm
regulation of cell shape GO:0008360 1 0.027
negative regulation of programmed cell death GO:0043069 58 0.027
regulation of cell morphogenesis GO:0022604 42 0.027
rna localization GO:0006403 4 0.027
anterior posterior pattern specification GO:0009952 152 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
neuron projection extension GO:1990138 45 0.026
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.026
vasculature development GO:0001944 278 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
multi organism process GO:0051704 134 0.025
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
Human Fly
camera type eye development GO:0043010 222 0.025
cellular component morphogenesis GO:0032989 336 0.025
Worm
embryonic heart tube development GO:0035050 133 0.025
cellular component assembly GO:0022607 170 0.024
Human
cell motility GO:0048870 244 0.024
Human Worm
establishment of protein localization to organelle GO:0072594 4 0.024
angiogenesis GO:0001525 158 0.024
positive regulation of hydrolase activity GO:0051345 13 0.024
Human
positive regulation of proteolysis GO:0045862 10 0.024
Human
regulation of molecular function GO:0065009 70 0.024
Human Yeast
regulation of apoptotic signaling pathway GO:2001233 12 0.023
Human
cell part morphogenesis GO:0032990 246 0.023
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
protein metabolic process GO:0019538 183 0.023
Human Yeast Rat
cellular component disassembly GO:0022411 1 0.023
negative regulation of apoptotic process GO:0043066 55 0.023
axon development GO:0061564 166 0.022
Worm
negative regulation of cellular metabolic process GO:0031324 77 0.022
Human Yeast Rat
positive regulation of multicellular organismal process GO:0051240 52 0.022
pancreas development GO:0031016 84 0.022
cytokinesis GO:0000910 3 0.022
Worm
aromatic compound biosynthetic process GO:0019438 217 0.022
translational initiation GO:0006413 3 0.022
mitotic cell cycle checkpoint GO:0007093 5 0.022
negative regulation of dna metabolic process GO:0051053 4 0.021
protein import GO:0017038 3 0.021
phosphorus metabolic process GO:0006793 109 0.021
Human Yeast
neuron development GO:0048666 262 0.021
Worm
protein secretion GO:0009306 1 0.021
response to external biotic stimulus GO:0043207 97 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
Human Fly
homeostatic process GO:0042592 142 0.021
Human Yeast Fly
oxoacid metabolic process GO:0043436 31 0.020
negative regulation of biological process GO:0048519 304 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
Human
response to organic substance GO:0010033 153 0.020
Yeast
positive regulation of response to stimulus GO:0048584 80 0.020
Human
myeloid cell development GO:0061515 32 0.020
leukocyte differentiation GO:0002521 25 0.020
cellular macromolecule catabolic process GO:0044265 12 0.020
Human
dorsal ventral pattern formation GO:0009953 125 0.020
kupffer s vesicle development GO:0070121 50 0.020
blood vessel development GO:0001568 246 0.019
phosphorylation GO:0016310 69 0.019
Human
meiotic chromosome segregation GO:0045132 3 0.019
negative regulation of metabolic process GO:0009892 86 0.019
Human Yeast Rat
chemotaxis GO:0006935 104 0.019
Worm
erythrocyte differentiation GO:0030218 54 0.019
lymphocyte proliferation GO:0046651 1 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
regulation of mitotic cell cycle GO:0007346 25 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.018
Worm
organonitrogen compound metabolic process GO:1901564 74 0.018
Human Yeast
regulation of cell division GO:0051302 12 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
response to other organism GO:0051707 97 0.018
cell morphogenesis GO:0000902 289 0.018
Worm
response to transition metal nanoparticle GO:1990267 28 0.018
carbohydrate homeostasis GO:0033500 1 0.018
Yeast
organic acid metabolic process GO:0006082 31 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
Human
response to abiotic stimulus GO:0009628 122 0.018
spermatogenesis GO:0007283 7 0.018
cellular protein metabolic process GO:0044267 129 0.017
Human Yeast Rat
cell division GO:0051301 20 0.017
macromolecule localization GO:0033036 54 0.017
positive regulation of molecular function GO:0044093 33 0.017
Human
positive regulation of signaling GO:0023056 56 0.017
Human
cell projection morphogenesis GO:0048858 244 0.017
Worm
single organism nuclear import GO:1902593 3 0.017
establishment of localization in cell GO:0051649 77 0.016
regulation of protein metabolic process GO:0051246 56 0.016
Human Yeast Rat
spindle organization GO:0007051 5 0.016
protein localization GO:0008104 40 0.016
interspecies interaction between organisms GO:0044419 4 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
Human Yeast
negative regulation of signaling GO:0023057 96 0.016
positive regulation of cell death GO:0010942 29 0.016
Human
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
meiotic spindle organization GO:0000212 1 0.016
regulation of peptidase activity GO:0052547 23 0.016
Human
regulation of cellular component organization GO:0051128 86 0.015
Human Rat
innate immune response GO:0045087 13 0.015
fertilization GO:0009566 3 0.015
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.015
axon guidance GO:0007411 86 0.015
Worm
dna metabolic process GO:0006259 27 0.015
immune response GO:0006955 28 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
negative regulation of signal transduction GO:0009968 94 0.015
muscle organ development GO:0007517 101 0.015
spermatid differentiation GO:0048515 2 0.015
neuron apoptotic process GO:0051402 20 0.015
somatic stem cell maintenance GO:0035019 1 0.015
rna metabolic process GO:0016070 219 0.014
translation GO:0006412 5 0.014
Yeast Rat
regulation of cell differentiation GO:0045595 142 0.014
negative regulation of cell death GO:0060548 60 0.014
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
spermatid development GO:0007286 2 0.014
regulation of neuron apoptotic process GO:0043523 17 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.014
brain development GO:0007420 293 0.014
positive regulation of gene expression GO:0010628 71 0.014
protein import into nucleus GO:0006606 3 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.014
Worm
regulation of localization GO:0032879 104 0.014
positive regulation of cell communication GO:0010647 56 0.014
Human
neuron remodeling GO:0016322 1 0.013
regulation of developmental growth GO:0048638 38 0.013
erythrocyte homeostasis GO:0034101 55 0.013
regulation of synapse organization GO:0050807 3 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
nucleic acid transport GO:0050657 2 0.013
regulation of protein targeting GO:1903533 2 0.013
single organism biosynthetic process GO:0044711 71 0.013
Fly
regulation of stem cell proliferation GO:0072091 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
Human Yeast Mouse
glucose homeostasis GO:0042593 1 0.013
Yeast
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
Human
lymphocyte differentiation GO:0030098 9 0.013
neurological system process GO:0050877 62 0.013
post embryonic development GO:0009791 7 0.013
Worm
cellular component movement GO:0006928 335 0.013
Human Worm
cellular response to stress GO:0033554 62 0.013
Human Mouse Fly
eye morphogenesis GO:0048592 144 0.012
positive regulation of cytokine production GO:0001819 2 0.012
female gamete generation GO:0007292 14 0.012
Fly
establishment of localization GO:0051234 244 0.012
Human Mouse Rat
trabecula morphogenesis GO:0061383 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
Human
epithelial tube morphogenesis GO:0060562 148 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
regulation of catalytic activity GO:0050790 55 0.012
Human Yeast
regulation of programmed cell death GO:0043067 101 0.012
Human
negative regulation of cell cycle process GO:0010948 9 0.012
response to wounding GO:0009611 116 0.012
cell type specific apoptotic process GO:0097285 22 0.011
regulation of cell activation GO:0050865 1 0.011
female meiotic division GO:0007143 2 0.011
Worm
response to oxygen levels GO:0070482 25 0.011
ras protein signal transduction GO:0007265 7 0.011
response to oxygen containing compound GO:1901700 55 0.011
Human Yeast Mouse
small molecule metabolic process GO:0044281 77 0.011
Human Yeast
regulation of nucleotide catabolic process GO:0030811 2 0.011
Human
stem cell differentiation GO:0048863 117 0.011
sensory organ morphogenesis GO:0090596 200 0.011
lymphocyte homeostasis GO:0002260 1 0.011
mononuclear cell proliferation GO:0032943 1 0.011
mesoderm development GO:0007498 88 0.011
embryonic pattern specification GO:0009880 44 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
organelle localization GO:0051640 49 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
Human
rna processing GO:0006396 25 0.011
regulation of inflammatory response GO:0050727 2 0.011
single organism cell adhesion GO:0098602 29 0.010
ribonucleoprotein complex biogenesis GO:0022613 13 0.010
establishment of organelle localization GO:0051656 45 0.010
cellular protein modification process GO:0006464 100 0.010
Human
pigmentation GO:0043473 85 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
Yeast Rat
positive regulation of peptidase activity GO:0010952 10 0.010
Human
neuroblast differentiation GO:0014016 1 0.010
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.010
macromolecule catabolic process GO:0009057 15 0.010
Human
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
Worm
organelle fission GO:0048285 23 0.010
Worm
positive regulation of transcription dna templated GO:0045893 57 0.010
protein targeting to nucleus GO:0044744 3 0.010

gnb2l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.282
immune system disease DOID:2914 0 0.066
nervous system disease DOID:863 0 0.041
congenital hypoplastic anemia DOID:1342 0 0.018
diamond blackfan anemia DOID:1339 0 0.018
aplastic anemia DOID:12449 0 0.018
bone marrow disease DOID:4961 0 0.018
anemia DOID:2355 0 0.018
hematopoietic system disease DOID:74 0 0.018
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
colorectal cancer DOID:9256 0 0.011