Danio rerio

57 known processes

popdc2

popeye domain containing 2

(Aliases: MGC158519)

popdc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle cell differentiation GO:0051146 129 0.388
system process GO:0003008 185 0.277
regulation of organelle assembly GO:1902115 4 0.274
muscle tissue development GO:0060537 110 0.240
rna biosynthetic process GO:0032774 181 0.224
heart looping GO:0001947 94 0.219
specification of symmetry GO:0009799 204 0.217
striated muscle tissue development GO:0014706 110 0.215
muscle cell differentiation GO:0042692 139 0.212
skeletal muscle tissue development GO:0007519 67 0.193
determination of left right symmetry GO:0007368 179 0.192
cardiac muscle cell differentiation GO:0055007 30 0.190
heart development GO:0007507 313 0.188
regulation of sarcomere organization GO:0060297 2 0.184
muscle cell development GO:0055001 115 0.175
muscle organ development GO:0007517 101 0.161
regulation of muscle contraction GO:0006937 3 0.135
somatic muscle development GO:0007525 4 0.133
muscle structure development GO:0061061 196 0.133
striated muscle cell development GO:0055002 108 0.131
tube morphogenesis GO:0035239 349 0.128
skeletal muscle organ development GO:0060538 78 0.122
embryonic heart tube development GO:0035050 133 0.122
heart morphogenesis GO:0003007 156 0.121
embryonic organ morphogenesis GO:0048562 274 0.118
cardiac muscle tissue development GO:0048738 48 0.114
embryonic heart tube morphogenesis GO:0003143 108 0.111
neuron differentiation GO:0030182 353 0.105
determination of bilateral symmetry GO:0009855 204 0.103
multicellular organismal signaling GO:0035637 22 0.103
larval development GO:0002164 2 0.098
heart contraction GO:0060047 71 0.095
tissue remodeling GO:0048771 4 0.095
embryonic organ development GO:0048568 381 0.090
actin filament based process GO:0030029 64 0.089
cardiocyte differentiation GO:0035051 44 0.087
heart process GO:0003015 71 0.087
organic cyclic compound metabolic process GO:1901360 301 0.085
epithelial tube morphogenesis GO:0060562 148 0.084
blood circulation GO:0008015 87 0.082
locomotion GO:0040011 313 0.081
nitrogen compound metabolic process GO:0006807 319 0.079
cardiac muscle cell development GO:0055013 20 0.079
actomyosin structure organization GO:0031032 53 0.077
regulation of rna metabolic process GO:0051252 224 0.071
cellular macromolecule metabolic process GO:0044260 391 0.070
cell projection organization GO:0030030 284 0.069
neuron projection development GO:0031175 180 0.069
nucleobase containing compound metabolic process GO:0006139 274 0.067
regulation of system process GO:0044057 40 0.067
regulation of biological quality GO:0065008 263 0.067
organelle organization GO:0006996 227 0.066
regulation of transcription dna templated GO:0006355 213 0.063
gene expression GO:0010467 252 0.062
cellular component morphogenesis GO:0032989 336 0.060
notochord development GO:0030903 54 0.059
adult behavior GO:0030534 2 0.058
actin filament based movement GO:0030048 1 0.057
cellular aromatic compound metabolic process GO:0006725 295 0.057
somite development GO:0061053 96 0.055
myofibril assembly GO:0030239 48 0.053
skeletal muscle myosin thick filament assembly GO:0030241 5 0.052
transport GO:0006810 220 0.052
head development GO:0060322 303 0.051
regulation of rna biosynthetic process GO:2001141 213 0.051
cell substrate adhesion GO:0031589 4 0.051
gastrulation GO:0007369 208 0.050
skeletal myofibril assembly GO:0014866 7 0.050
establishment of localization GO:0051234 244 0.049
regulation of developmental process GO:0050793 247 0.048
organelle assembly GO:0070925 110 0.048
transmembrane transport GO:0055085 120 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.046
regulation of blood circulation GO:1903522 32 0.046
sarcomerogenesis GO:0048769 4 0.045
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.044
cellular component biogenesis GO:0044085 178 0.044
digestive tract morphogenesis GO:0048546 231 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
regulation of multicellular organismal process GO:0051239 277 0.043
monovalent inorganic cation transport GO:0015672 42 0.043
regulation of heart contraction GO:0008016 32 0.042
digestive tract development GO:0048565 265 0.042
cardiac cell development GO:0055006 21 0.042
cellular component movement GO:0006928 335 0.042
neuron development GO:0048666 262 0.041
muscle fiber development GO:0048747 52 0.040
myotube differentiation GO:0014902 45 0.039
positive regulation of biological process GO:0048518 253 0.039
regulation of cellular biosynthetic process GO:0031326 245 0.038
cardiac myofibril assembly GO:0055003 9 0.038
aging GO:0007568 2 0.038
atp catabolic process GO:0006200 4 0.038
nucleic acid templated transcription GO:0097659 181 0.037
cytokinesis GO:0000910 3 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.037
regulation of ion transmembrane transport GO:0034765 18 0.037
regulation of heart growth GO:0060420 2 0.036
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
regulation of synapse assembly GO:0051963 3 0.035
cell proliferation involved in heart morphogenesis GO:0061323 2 0.035
regulation of multicellular organismal development GO:2000026 223 0.034
signal transduction GO:0007165 455 0.034
cardiac muscle myosin thick filament assembly GO:0071690 1 0.034
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
regulation of metabolic process GO:0019222 359 0.033
nucleic acid metabolic process GO:0090304 244 0.032
heterocycle metabolic process GO:0046483 290 0.032
bmp signaling pathway GO:0030509 52 0.032
actin cytoskeleton organization GO:0030036 63 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
regulation of membrane potential GO:0042391 23 0.031
rna metabolic process GO:0016070 219 0.031
regulation of primary metabolic process GO:0080090 311 0.031
intracellular signal transduction GO:0035556 85 0.030
regulation of anatomical structure morphogenesis GO:0022603 130 0.030
cell morphogenesis GO:0000902 289 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.029
transmission of nerve impulse GO:0019226 19 0.029
voluntary skeletal muscle contraction GO:0003010 4 0.029
cytoskeleton organization GO:0007010 96 0.029
angiogenesis GO:0001525 158 0.028
cytokinetic process GO:0032506 2 0.028
locomotory behavior GO:0007626 34 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
meiotic nuclear division GO:0007126 4 0.028
cardiac atrium morphogenesis GO:0003209 2 0.027
cardiac muscle fiber development GO:0048739 3 0.027
blood vessel development GO:0001568 246 0.027
small molecule metabolic process GO:0044281 77 0.027
single organism organelle organization GO:1902589 199 0.027
sarcomere organization GO:0045214 26 0.027
inorganic cation transmembrane transport GO:0098662 50 0.027
positive regulation of blood circulation GO:1903524 2 0.027
positive regulation of transcription dna templated GO:0045893 57 0.026
vasculature development GO:0001944 278 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
generation of neurons GO:0048699 385 0.026
central nervous system development GO:0007417 387 0.025
cell part morphogenesis GO:0032990 246 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
determination of heart left right asymmetry GO:0061371 117 0.025
cell projection morphogenesis GO:0048858 244 0.025
digestive system development GO:0055123 289 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
positive regulation of striated muscle tissue development GO:0045844 1 0.024
inositol lipid mediated signaling GO:0048017 2 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.023
cardiac conduction GO:0061337 3 0.023
sodium ion transmembrane transport GO:0035725 21 0.023
rna localization GO:0006403 4 0.023
single organism metabolic process GO:0044710 217 0.023
organic substance biosynthetic process GO:1901576 289 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
regulation of organelle organization GO:0033043 29 0.022
positive regulation of muscle tissue development GO:1901863 1 0.022
circulatory system process GO:0003013 87 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
cellular biosynthetic process GO:0044249 286 0.022
somitogenesis GO:0001756 87 0.022
regionalization GO:0003002 274 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
regulation of gene expression GO:0010468 265 0.021
brain development GO:0007420 293 0.021
cell motility GO:0048870 244 0.021
cellular component assembly GO:0022607 170 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
sleep GO:0030431 1 0.020
neurotransmitter transport GO:0006836 2 0.020
positive regulation of transport GO:0051050 2 0.020
regulation of filopodium assembly GO:0051489 2 0.019
cell death in response to oxidative stress GO:0036473 2 0.019
blood vessel morphogenesis GO:0048514 216 0.019
action potential GO:0001508 19 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
sensory organ morphogenesis GO:0090596 200 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.018
organic acid metabolic process GO:0006082 31 0.018
atrial cardiac muscle cell development GO:0055014 4 0.018
regulation of organ growth GO:0046620 3 0.018
stem cell proliferation GO:0072089 4 0.018
regulation of reproductive process GO:2000241 4 0.018
mitochondrion organization GO:0007005 4 0.018
peptidyl lysine methylation GO:0018022 3 0.018
behavior GO:0007610 74 0.018
regulation of cell development GO:0060284 100 0.018
neurological system process GO:0050877 62 0.018
regulation of biosynthetic process GO:0009889 250 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
nephron epithelium morphogenesis GO:0072088 1 0.017
ventricular cardiac myofibril assembly GO:0055005 4 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
oxoacid metabolic process GO:0043436 31 0.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.017
positive regulation of rna metabolic process GO:0051254 59 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
regulation of metal ion transport GO:0010959 4 0.017
regulation of dendrite development GO:0050773 3 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
actin mediated cell contraction GO:0070252 1 0.017
positive regulation of gene expression GO:0010628 71 0.017
skeletal muscle fiber development GO:0048741 35 0.017
atrial cardiac myofibril assembly GO:0055004 2 0.017
ventricular cardiac muscle tissue development GO:0003229 3 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
positive regulation of metabolic process GO:0009893 108 0.016
axon development GO:0061564 166 0.016
regulation of cellular response to oxidative stress GO:1900407 2 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
ion transmembrane transport GO:0034220 91 0.016
regulation of skeletal muscle fiber development GO:0048742 2 0.016
amine metabolic process GO:0009308 2 0.016
regulation of heart rate GO:0002027 5 0.016
segmentation GO:0035282 97 0.016
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.016
regulation of blood pressure GO:0008217 1 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
regulation of calcium ion transport GO:0051924 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of response to stimulus GO:0048583 269 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
regulation of transporter activity GO:0032409 2 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
cardiac atrium development GO:0003230 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
eye morphogenesis GO:0048592 144 0.015
chordate embryonic development GO:0043009 271 0.015
establishment of protein localization to organelle GO:0072594 4 0.014
protein dephosphorylation GO:0006470 3 0.014
response to external stimulus GO:0009605 264 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cardiac muscle cell contraction GO:0086003 1 0.014
myotube cell development GO:0014904 35 0.014
cardiac conduction system development GO:0003161 1 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
mechanosensory behavior GO:0007638 2 0.014
sensory organ development GO:0007423 393 0.014
cation transmembrane transport GO:0098655 65 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
cation transport GO:0006812 81 0.014
peptidyl serine modification GO:0018209 2 0.014
positive regulation of heart contraction GO:0045823 2 0.014
cell matrix adhesion GO:0007160 4 0.014
renal system development GO:0072001 94 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
cell aging GO:0007569 2 0.013
forebrain development GO:0030900 96 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
atrial ventricular junction remodeling GO:0003294 2 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
ameboidal type cell migration GO:0001667 143 0.013
sex determination GO:0007530 1 0.013
regeneration GO:0031099 91 0.013
cell adhesion GO:0007155 40 0.013
developmental growth GO:0048589 166 0.013
twitch skeletal muscle contraction GO:0014721 4 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
single organism transport GO:0044765 206 0.013
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.013
biosynthetic process GO:0009058 294 0.013
renal tubule morphogenesis GO:0061333 1 0.013
amino acid transport GO:0006865 2 0.012
multicellular organism growth GO:0035264 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
regulation of jak stat cascade GO:0046425 3 0.012
meiotic cell cycle process GO:1903046 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
renal system vasculature development GO:0061437 2 0.012
protein stabilization GO:0050821 2 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
biological adhesion GO:0022610 40 0.012
regulation of myotube differentiation GO:0010830 2 0.012
inner ear development GO:0048839 126 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
regulation of cardiac muscle tissue development GO:0055024 1 0.012
phosphorus metabolic process GO:0006793 109 0.012
response to chemical GO:0042221 320 0.012
regulation of actin filament based process GO:0032970 9 0.012
somite specification GO:0001757 12 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
response to alkaloid GO:0043279 2 0.012
stem cell differentiation GO:0048863 117 0.012
negative regulation of cellular process GO:0048523 283 0.012
cellular amine metabolic process GO:0044106 2 0.012
hemostasis GO:0007599 13 0.011
regulation of cell differentiation GO:0045595 142 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
myeloid cell differentiation GO:0030099 86 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
protein localization to nucleus GO:0034504 3 0.011
pronephric duct development GO:0039022 13 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
cellular response to nutrient levels GO:0031669 2 0.011
cellular ketone metabolic process GO:0042180 11 0.011
growth GO:0040007 174 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
neuronal action potential GO:0019228 18 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
eye development GO:0001654 277 0.011
heart valve development GO:0003170 14 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
single organism membrane fusion GO:0044801 2 0.011
cardiac chamber formation GO:0003207 4 0.011
regulation of organ morphogenesis GO:2000027 35 0.011
nucleobase containing compound catabolic process GO:0034655 15 0.011
cell fate specification GO:0001708 68 0.011
gtp catabolic process GO:0006184 2 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.011
spermatid development GO:0007286 2 0.011
regulation of cardiac muscle cell contraction GO:0086004 1 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of apoptotic process GO:0042981 98 0.010
regulation of ion transport GO:0043269 22 0.010
mesenchymal cell differentiation GO:0048762 87 0.010
trabecula morphogenesis GO:0061383 2 0.010
regulation of tube size GO:0035150 2 0.010
fatty acid catabolic process GO:0009062 1 0.010
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.010
regulation of signaling GO:0023051 235 0.010
cell migration GO:0016477 237 0.010
homeostasis of number of cells GO:0048872 62 0.010
regulation of blood vessel size GO:0050880 2 0.010
heart jogging GO:0003146 40 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
sensory perception of pain GO:0019233 1 0.010

popdc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.136
muscular disease DOID:0080000 0 0.136
heart disease DOID:114 0 0.136
cardiomyopathy DOID:0050700 0 0.136
disease of anatomical entity DOID:7 0 0.136
intrinsic cardiomyopathy DOID:0060036 0 0.136
cardiovascular system disease DOID:1287 0 0.136
musculoskeletal system disease DOID:17 0 0.136
muscle tissue disease DOID:66 0 0.136
hypertrophic cardiomyopathy DOID:11984 0 0.081
nervous system disease DOID:863 0 0.013