Danio rerio

0 known processes

gtf2b

general transcription factor IIB

(Aliases: zgc:66258,wu:fc44c11)

gtf2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.310
regulation of meiotic cell cycle GO:0051445 1 0.257
larval development GO:0002164 2 0.199
regulation of primary metabolic process GO:0080090 311 0.143
Fly
organelle organization GO:0006996 227 0.133
response to chemical GO:0042221 320 0.123
nucleobase containing compound metabolic process GO:0006139 274 0.116
Fly
cell motility GO:0048870 244 0.113
cellular nitrogen compound metabolic process GO:0034641 290 0.108
Fly
cell projection morphogenesis GO:0048858 244 0.107
embryo development ending in birth or egg hatching GO:0009792 271 0.104
Worm
positive regulation of cellular process GO:0048522 201 0.103
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.099
transcription dna templated GO:0006351 181 0.096
Fly
positive regulation of biological process GO:0048518 253 0.093
nucleic acid metabolic process GO:0090304 244 0.091
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.089
modification dependent protein catabolic process GO:0019941 3 0.089
cell cycle g1 s phase transition GO:0044843 1 0.086
locomotion GO:0040011 313 0.086
meiotic chromosome segregation GO:0045132 3 0.085
modification dependent macromolecule catabolic process GO:0043632 3 0.085
regulation of cell shape GO:0008360 1 0.084
regulation of multicellular organismal process GO:0051239 277 0.080
positive regulation of cell cycle GO:0045787 3 0.080
cellular component movement GO:0006928 335 0.077
nuclear division GO:0000280 23 0.073
g1 s transition of mitotic cell cycle GO:0000082 1 0.072
negative regulation of cellular process GO:0048523 283 0.067
development of primary female sexual characteristics GO:0046545 4 0.066
cell migration GO:0016477 237 0.066
nucleic acid templated transcription GO:0097659 181 0.063
Fly
cellular component morphogenesis GO:0032989 336 0.062
single organism organelle organization GO:1902589 199 0.061
regulation of cellular metabolic process GO:0031323 320 0.060
Fly
cell projection organization GO:0030030 284 0.060
response to stress GO:0006950 263 0.059
ubiquitin dependent protein catabolic process GO:0006511 3 0.059
response to uv GO:0009411 3 0.059
localization of cell GO:0051674 244 0.058
response to external stimulus GO:0009605 264 0.057
cell morphogenesis GO:0000902 289 0.056
nitrogen compound metabolic process GO:0006807 319 0.056
Fly
regulation of mrna processing GO:0050684 3 0.056
gene expression GO:0010467 252 0.056
Fly
cellular protein catabolic process GO:0044257 4 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.053
meiosis i GO:0007127 1 0.050
regulation of developmental process GO:0050793 247 0.049
protein metabolic process GO:0019538 183 0.047
chromosome organization GO:0051276 31 0.046
female gonad development GO:0008585 4 0.046
protein k48 linked ubiquitination GO:0070936 1 0.044
dna templated transcription elongation GO:0006354 3 0.044
cortical actin cytoskeleton organization GO:0030866 1 0.042
negative regulation of biological process GO:0048519 304 0.041
response to abiotic stimulus GO:0009628 122 0.041
regulation of biological quality GO:0065008 263 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
organic substance biosynthetic process GO:1901576 289 0.040
Fly
heterocycle metabolic process GO:0046483 290 0.040
Fly
chromosome organization involved in meiosis GO:0070192 1 0.040
cellular macromolecule metabolic process GO:0044260 391 0.039
Fly
response to biotic stimulus GO:0009607 97 0.039
meiotic cell cycle process GO:1903046 3 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.038
Fly
lipid homeostasis GO:0055088 3 0.038
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.036
regulation of metabolic process GO:0019222 359 0.036
Fly
establishment of localization GO:0051234 244 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.034
Fly
multi organism process GO:0051704 134 0.034
double strand break repair via homologous recombination GO:0000724 1 0.034
regulation of multicellular organismal development GO:2000026 223 0.033
regulation of cell differentiation GO:0045595 142 0.032
death GO:0016265 121 0.032
single organism reproductive process GO:0044702 40 0.032
autophagy GO:0006914 4 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
Fly
single organism localization GO:1902578 225 0.031
neuron development GO:0048666 262 0.031
female sex differentiation GO:0046660 4 0.031
cellular biosynthetic process GO:0044249 286 0.031
Fly
organic cyclic compound metabolic process GO:1901360 301 0.031
Fly
sensory organ development GO:0007423 393 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Fly
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of cell proliferation GO:0042127 37 0.030
regulation of rna metabolic process GO:0051252 224 0.030
Fly
regulation of gene expression GO:0010468 265 0.030
Fly
heterocycle biosynthetic process GO:0018130 215 0.029
Fly
cellular protein metabolic process GO:0044267 129 0.029
regulation of transcription dna templated GO:0006355 213 0.029
Fly
cellular response to organic substance GO:0071310 105 0.029
compound eye development GO:0048749 2 0.029
regulation of synapse organization GO:0050807 3 0.028
rna biosynthetic process GO:0032774 181 0.028
Fly
mitochondrion organization GO:0007005 4 0.028
regulation of chromosome segregation GO:0051983 1 0.028
positive regulation of catabolic process GO:0009896 4 0.027
single fertilization GO:0007338 3 0.027
mitotic cell cycle GO:0000278 64 0.027
recombinational repair GO:0000725 1 0.027
positive regulation of chromatin modification GO:1903310 1 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.027
Fly
response to external biotic stimulus GO:0043207 97 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
negative regulation of synapse assembly GO:0051964 2 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
single organism metabolic process GO:0044710 217 0.026
rna metabolic process GO:0016070 219 0.026
Fly
transport GO:0006810 220 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
Fly
fertilization GO:0009566 3 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.025
Fly
neuroblast proliferation GO:0007405 2 0.025
response to other organism GO:0051707 97 0.025
cell part morphogenesis GO:0032990 246 0.025
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
Fly
meiosis ii GO:0007135 1 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
maintenance of location GO:0051235 4 0.024
cellular response to radiation GO:0071478 4 0.024
vasculature development GO:0001944 278 0.023
dna templated transcription initiation GO:0006352 1 0.023
Fly
generation of neurons GO:0048699 385 0.022
cellular response to starvation GO:0009267 1 0.022
regulation of reproductive process GO:2000241 4 0.022
regulation of protein complex assembly GO:0043254 3 0.022
aging GO:0007568 2 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of gene expression epigenetic GO:0040029 11 0.022
organelle fission GO:0048285 23 0.022
microtubule based process GO:0007017 60 0.022
regulation of cellular component organization GO:0051128 86 0.022
protein secretion GO:0009306 1 0.022
double strand break repair GO:0006302 3 0.021
heart development GO:0007507 313 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
Fly
cellular response to chemical stimulus GO:0070887 157 0.021
signal transduction GO:0007165 455 0.021
lipid storage GO:0019915 1 0.020
response to temperature stimulus GO:0009266 15 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
cell cycle GO:0007049 93 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.020
chordate embryonic development GO:0043009 271 0.020
neuron differentiation GO:0030182 353 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
post golgi vesicle mediated transport GO:0006892 1 0.020
regulation of response to stimulus GO:0048583 269 0.020
blood vessel development GO:0001568 246 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of signaling GO:0023051 235 0.019
negative regulation of metabolic process GO:0009892 86 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular response to light stimulus GO:0071482 4 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
proteolysis GO:0006508 38 0.019
positive regulation of gene expression GO:0010628 71 0.018
cellular response to nutrient levels GO:0031669 2 0.018
apoptotic process GO:0006915 116 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
developmental growth GO:0048589 166 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
cytoskeleton organization GO:0007010 96 0.018
membrane fusion GO:0061025 2 0.018
mrna metabolic process GO:0016071 20 0.018
positive regulation of transport GO:0051050 2 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of biosynthetic process GO:0009889 250 0.018
Fly
single organism membrane fusion GO:0044801 2 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
cellular component assembly GO:0022607 170 0.017
eye development GO:0001654 277 0.017
regulation of organelle organization GO:0033043 29 0.017
apoptotic process involved in development GO:1902742 2 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
Fly
microtubule cytoskeleton organization GO:0000226 33 0.016
gene silencing GO:0016458 4 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
embryonic organ development GO:0048568 381 0.016
mononuclear cell proliferation GO:0032943 1 0.016
response to organic substance GO:0010033 153 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
macromolecule modification GO:0043412 111 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of apoptotic process GO:0042981 98 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of protein catabolic process GO:0042176 1 0.015
mitochondrial transport GO:0006839 2 0.015
hemopoiesis GO:0030097 183 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
blood vessel morphogenesis GO:0048514 216 0.015
macroautophagy GO:0016236 1 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
muscle organ development GO:0007517 101 0.015
regulation of synapse assembly GO:0051963 3 0.015
protein phosphorylation GO:0006468 47 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
posttranscriptional gene silencing GO:0016441 3 0.015
cellular protein modification process GO:0006464 100 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
mitotic nuclear division GO:0007067 18 0.015
response to lipid GO:0033993 60 0.014
programmed cell death GO:0012501 119 0.014
neuron projection extension GO:1990138 45 0.014
cell cycle process GO:0022402 53 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
response to heat GO:0009408 6 0.014
digestive tract development GO:0048565 265 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
intracellular mrna localization GO:0008298 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
hatching GO:0035188 4 0.014
interspecies interaction between organisms GO:0044419 4 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
anterior posterior pattern specification GO:0009952 152 0.014
biological adhesion GO:0022610 40 0.014
lipid metabolic process GO:0006629 52 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of inflammatory response GO:0050727 2 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
immune system development GO:0002520 191 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
regulation of tube size GO:0035150 2 0.014
histone h3 k4 methylation GO:0051568 2 0.014
mitotic cell cycle process GO:1903047 48 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
protein polyubiquitination GO:0000209 4 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
stem cell proliferation GO:0072089 4 0.013
microtubule based movement GO:0007018 33 0.013
myeloid cell differentiation GO:0030099 86 0.013
spermatid development GO:0007286 2 0.013
homeostatic process GO:0042592 142 0.013
regulation of signal transduction GO:0009966 225 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
determination of left right symmetry GO:0007368 179 0.013
multicellular organism reproduction GO:0032504 35 0.013
regulation of cell activation GO:0050865 1 0.013
regionalization GO:0003002 274 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
response to topologically incorrect protein GO:0035966 2 0.013
positive regulation of signaling GO:0023056 56 0.013
neuron projection morphogenesis GO:0048812 161 0.013
gastrulation GO:0007369 208 0.013
protein modification process GO:0036211 100 0.013
regulation of blood vessel size GO:0050880 2 0.013
atp catabolic process GO:0006200 4 0.013
positive regulation of signal transduction GO:0009967 56 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
acylglycerol homeostasis GO:0055090 2 0.012
phagocytosis GO:0006909 3 0.012
regulation of cell cycle GO:0051726 52 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
protein localization to nucleus GO:0034504 3 0.012
determination of bilateral symmetry GO:0009855 204 0.012
intracellular signal transduction GO:0035556 85 0.012
segmentation GO:0035282 97 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of binding GO:0051098 3 0.012
Fly
cell growth GO:0016049 57 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
pronuclear migration GO:0035046 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
Fly
positive regulation of metabolic process GO:0009893 108 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
gtp metabolic process GO:0046039 4 0.011
negative regulation of molecular function GO:0044092 23 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
protein import GO:0017038 3 0.011
golgi vesicle transport GO:0048193 3 0.011
cell proliferation GO:0008283 80 0.011
angiogenesis GO:0001525 158 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of gene expression GO:0010629 65 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
response to wounding GO:0009611 116 0.011
negative regulation of signal transduction GO:0009968 94 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Fly
actin filament based movement GO:0030048 1 0.011
developmental programmed cell death GO:0010623 4 0.011
cytoplasm organization GO:0007028 4 0.011
growth GO:0040007 174 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
defense response GO:0006952 47 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
pole plasm assembly GO:0007315 4 0.011
multi organism cellular process GO:0044764 2 0.011
cell adhesion GO:0007155 40 0.011
reproduction GO:0000003 40 0.011
somitogenesis GO:0001756 87 0.011
cell division GO:0051301 20 0.010
single organism nuclear import GO:1902593 3 0.010
cell death GO:0008219 121 0.010
establishment of organelle localization GO:0051656 45 0.010
developmental cell growth GO:0048588 52 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
response to organic cyclic compound GO:0014070 51 0.010
response to light stimulus GO:0009416 46 0.010
cell cycle arrest GO:0007050 1 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.010
post embryonic morphogenesis GO:0009886 4 0.010
positive regulation of secretion by cell GO:1903532 1 0.010

gtf2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.011