Danio rerio

23 known processes

lft2

lefty2

(Aliases: fe38b03,wu:fe38b03,cb720,atv2)

lft2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.999
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.987
tube morphogenesis GO:0035239 349 0.932
Mouse
regulation of heart morphogenesis GO:2000826 17 0.927
determination of left right asymmetry in nervous system GO:0035545 4 0.921
Zebrafish
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.915
embryonic organ morphogenesis GO:0048562 274 0.905
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.895
notochord development GO:0030903 54 0.846
gastrulation GO:0007369 208 0.846
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.833
Mouse
determination of heart left right asymmetry GO:0061371 117 0.831
Zebrafish
cardioblast migration GO:0003260 7 0.796
digestive tract development GO:0048565 265 0.796
Mouse
convergent extension involved in gastrulation GO:0060027 71 0.781
heart jogging GO:0003146 40 0.779
embryonic heart tube development GO:0035050 133 0.777
Zebrafish
cell migration GO:0016477 237 0.773
Mouse
digestive tract morphogenesis GO:0048546 231 0.766
Mouse
vasculature development GO:0001944 278 0.746
negative regulation of protein complex assembly GO:0031333 1 0.744
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.731
Mouse
negative regulation of mesodermal cell fate specification GO:0042662 3 0.720
convergent extension GO:0060026 118 0.704
organic cyclic compound biosynthetic process GO:1901362 223 0.703
Mouse
heart morphogenesis GO:0003007 156 0.695
blood vessel development GO:0001568 246 0.695
regulation of rna metabolic process GO:0051252 224 0.681
Mouse
regionalization GO:0003002 274 0.651
determination of left right symmetry GO:0007368 179 0.649
Zebrafish Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.647
cellular component movement GO:0006928 335 0.639
Mouse
bmp signaling pathway involved in heart jogging GO:0003303 14 0.634
determination of left right asymmetry in diencephalon GO:0035462 4 0.626
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.616
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.610
Mouse
cellular biosynthetic process GO:0044249 286 0.592
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.587
Mouse
heart field specification GO:0003128 1 0.578
heart valve formation GO:0003188 4 0.573
determination of dorsal ventral asymmetry GO:0048262 34 0.562
nucleic acid templated transcription GO:0097659 181 0.557
Mouse
cardiac chamber formation GO:0003207 4 0.556
determination of bilateral symmetry GO:0009855 204 0.556
Zebrafish Mouse
segmentation GO:0035282 97 0.554
regulation of metabolic process GO:0019222 359 0.547
Mouse
organ formation GO:0048645 17 0.541
spemann organizer formation GO:0060061 10 0.529
organic substance biosynthetic process GO:1901576 289 0.520
Mouse
embryonic eye morphogenesis GO:0048048 30 0.519
cell migration involved in gastrulation GO:0042074 79 0.514
Mouse
muscle tissue development GO:0060537 110 0.501
blood vessel morphogenesis GO:0048514 216 0.500
transcription from rna polymerase ii promoter GO:0006366 80 0.492
Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.490
heart looping GO:0001947 94 0.481
organic cyclic compound metabolic process GO:1901360 301 0.475
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.474
Mouse
rna metabolic process GO:0016070 219 0.471
Mouse
sensory organ morphogenesis GO:0090596 200 0.469
atrioventricular valve formation GO:0003190 3 0.466
nucleic acid metabolic process GO:0090304 244 0.459
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.451
Mouse
digestive system development GO:0055123 289 0.451
Mouse
localization of cell GO:0051674 244 0.443
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.441
Mouse
specification of symmetry GO:0009799 204 0.439
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.424
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.424
Mouse
epithelial tube morphogenesis GO:0060562 148 0.421
transcription dna templated GO:0006351 181 0.414
Mouse
regulation of cellular metabolic process GO:0031323 320 0.406
Mouse
signal transduction GO:0007165 455 0.405
Mouse
ventricular cardiac muscle cell differentiation GO:0055012 6 0.404
cell morphogenesis GO:0000902 289 0.404
rna biosynthetic process GO:0032774 181 0.385
Mouse
atrioventricular valve morphogenesis GO:0003181 6 0.381
heart formation GO:0060914 13 0.372
striated muscle tissue development GO:0014706 110 0.370
optic placode formation GO:0001743 4 0.369
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.369
regulation of nodal signaling pathway GO:1900107 4 0.368
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.366
Mouse
bmp signaling pathway involved in heart development GO:0061312 15 0.364
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.361
nucleobase containing compound biosynthetic process GO:0034654 205 0.356
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.350
regulation of primary metabolic process GO:0080090 311 0.344
Mouse
angiogenesis GO:0001525 158 0.342
formation of primary germ layer GO:0001704 62 0.342
optic placode formation involved in camera type eye formation GO:0046619 3 0.340
erythrocyte differentiation GO:0030218 54 0.338
embryonic pectoral fin morphogenesis GO:0035118 24 0.330
notochord morphogenesis GO:0048570 17 0.314
hepatic duct development GO:0061011 2 0.308
heart valve morphogenesis GO:0003179 8 0.304
embryonic heart tube left right pattern formation GO:0060971 5 0.297
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.292
cardiac atrium morphogenesis GO:0003209 2 0.283
morphogenesis of an epithelium GO:0002009 333 0.282
gall bladder development GO:0061010 1 0.281
eye morphogenesis GO:0048592 144 0.278
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.265
enzyme linked receptor protein signaling pathway GO:0007167 106 0.260
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.256
Mouse
embryonic pattern specification GO:0009880 44 0.254
macromolecule biosynthetic process GO:0009059 227 0.248
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.248
Mouse
muscle cell differentiation GO:0042692 139 0.248
biosynthetic process GO:0009058 294 0.236
Mouse
neuron differentiation GO:0030182 353 0.232
cell projection organization GO:0030030 284 0.227
dorsal ventral pattern formation GO:0009953 125 0.227
Zebrafish
cell motility GO:0048870 244 0.223
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.223
ear morphogenesis GO:0042471 64 0.222
cardiac cell fate commitment GO:0060911 1 0.221
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.217
Mouse
axon guidance GO:0007411 86 0.215
inner ear morphogenesis GO:0042472 63 0.213
determination of dorsal identity GO:0048263 13 0.209
cellular nitrogen compound metabolic process GO:0034641 290 0.206
Mouse
atrial ventricular junction remodeling GO:0003294 2 0.204
regulation of wnt signaling pathway GO:0030111 53 0.202
kupffer s vesicle development GO:0070121 50 0.198
negative regulation of rna metabolic process GO:0051253 48 0.198
Mouse
cerebellum formation GO:0021588 2 0.194
axial mesoderm formation GO:0048320 4 0.192
regulation of developmental process GO:0050793 247 0.192
wnt signaling pathway GO:0016055 80 0.191
hematopoietic or lymphoid organ development GO:0048534 191 0.190
regulation of organ morphogenesis GO:2000027 35 0.188
heterocycle metabolic process GO:0046483 290 0.188
Mouse
diencephalon development GO:0021536 58 0.185
Zebrafish
somitogenesis GO:0001756 87 0.185
anterior posterior pattern specification GO:0009952 152 0.181
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.180
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.180
Mouse
mesenchyme development GO:0060485 127 0.180
Zebrafish
floor plate morphogenesis GO:0033505 12 0.178
neuron projection development GO:0031175 180 0.178
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.177
limb bud formation GO:0060174 2 0.176
ventral midline development GO:0007418 13 0.171
heart development GO:0007507 313 0.157
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.156
generation of neurons GO:0048699 385 0.154
outflow tract morphogenesis GO:0003151 1 0.154
positive regulation of map kinase activity GO:0043406 3 0.154
regulation of gene expression GO:0010468 265 0.153
Mouse
erythrocyte homeostasis GO:0034101 55 0.153
axon development GO:0061564 166 0.149
cell part morphogenesis GO:0032990 246 0.147
negative regulation of biological process GO:0048519 304 0.146
Mouse
neuron development GO:0048666 262 0.142
response to endogenous stimulus GO:0009719 83 0.141
embryonic camera type eye morphogenesis GO:0048596 19 0.140
gastrulation with mouth forming second GO:0001702 44 0.138
peptide metabolic process GO:0006518 1 0.137
pharyngeal muscle development GO:0043282 4 0.135
cellular component morphogenesis GO:0032989 336 0.135
regulation of cell communication GO:0010646 232 0.134
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.133
Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.133
single organism organelle organization GO:1902589 199 0.131
cardiac chamber morphogenesis GO:0003206 12 0.131
neural crest cell differentiation GO:0014033 72 0.129
cell differentiation in spinal cord GO:0021515 40 0.129
cellular amide metabolic process GO:0043603 4 0.128
floor plate formation GO:0021508 12 0.127
cell migration involved in heart formation GO:0060974 10 0.127
positive regulation of cellular process GO:0048522 201 0.127
bmp signaling pathway GO:0030509 52 0.126
blood circulation GO:0008015 87 0.126
embryonic camera type eye development GO:0031076 29 0.124
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.122
chordate embryonic development GO:0043009 271 0.121
regulation of cardiac muscle tissue development GO:0055024 1 0.120
female gonad development GO:0008585 4 0.118
negative regulation of cellular process GO:0048523 283 0.115
Mouse
female sex differentiation GO:0046660 4 0.111
embryonic hemopoiesis GO:0035162 53 0.111
photoreceptor cell fate commitment GO:0046552 1 0.108
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.107
ameboidal type cell migration GO:0001667 143 0.107
Mouse
stem cell development GO:0048864 82 0.106
camera type eye development GO:0043010 222 0.106
eye development GO:0001654 277 0.106
response to chemical GO:0042221 320 0.105
Mouse
anterior posterior axis specification GO:0009948 20 0.105
Mouse
embryonic camera type eye formation GO:0060900 10 0.103
heart valve development GO:0003170 14 0.103
oligodendrocyte cell fate specification GO:0021778 4 0.102
regulation of macromolecule metabolic process GO:0060255 317 0.101
Mouse
mesendoderm development GO:0048382 10 0.097
somite development GO:0061053 96 0.097
response to retinoic acid GO:0032526 6 0.097
Mouse
epithelial to mesenchymal transition GO:0001837 21 0.097
cardiocyte differentiation GO:0035051 44 0.096
cell morphogenesis involved in differentiation GO:0000904 195 0.095
regulation of cell migration GO:0030334 40 0.094
axis specification GO:0009798 43 0.092
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.091
antimicrobial humoral response GO:0019730 2 0.089
ectoderm development GO:0007398 9 0.089
ectodermal placode formation GO:0060788 26 0.088
mesoderm development GO:0007498 88 0.087
Zebrafish
myeloid cell homeostasis GO:0002262 56 0.087
cardiac chamber development GO:0003205 19 0.085
skeletal muscle organ development GO:0060538 78 0.084
mesenchymal cell development GO:0014031 78 0.083
endoderm formation GO:0001706 29 0.083
axial mesodermal cell fate specification GO:0048327 3 0.082
nitrogen compound metabolic process GO:0006807 319 0.082
Mouse
kidney development GO:0001822 92 0.082
liver development GO:0001889 96 0.080
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.080
Mouse
non canonical wnt signaling pathway GO:0035567 13 0.080
negative regulation of transcription dna templated GO:0045892 45 0.080
Mouse
negative regulation of gastrulation GO:2000542 11 0.080
regulation of cellular component movement GO:0051270 55 0.080
taxis GO:0042330 109 0.079
notochord formation GO:0014028 6 0.079
retina development in camera type eye GO:0060041 146 0.078
endocrine system development GO:0035270 65 0.077
mediolateral intercalation GO:0060031 3 0.077
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.076
Mouse
tissue remodeling GO:0048771 4 0.076
nucleobase containing compound metabolic process GO:0006139 274 0.076
Mouse
mesoderm formation GO:0001707 43 0.075
locomotion GO:0040011 313 0.075
Mouse
regulation of localization GO:0032879 104 0.074
regulation of nitrogen compound metabolic process GO:0051171 251 0.074
Mouse
embryonic digestive tract development GO:0048566 4 0.073
foregut morphogenesis GO:0007440 4 0.071
regulation of anatomical structure morphogenesis GO:0022603 130 0.071
urogenital system development GO:0001655 97 0.070
positive regulation of cell cycle GO:0045787 3 0.069
retinal ganglion cell axon guidance GO:0031290 35 0.069
gene expression GO:0010467 252 0.068
Mouse
negative regulation of mesoderm development GO:2000381 5 0.067
positive regulation of rna metabolic process GO:0051254 59 0.066
muscle structure development GO:0061061 196 0.066
sensory organ development GO:0007423 393 0.063
development of primary female sexual characteristics GO:0046545 4 0.062
multi organism process GO:0051704 134 0.062
neural crest cell migration GO:0001755 42 0.062
atrioventricular valve development GO:0003171 11 0.062
cell projection morphogenesis GO:0048858 244 0.059
inner ear development GO:0048839 126 0.058
camera type eye morphogenesis GO:0048593 108 0.058
regulation of cardiac chamber morphogenesis GO:1901219 2 0.057
mesenchymal cell differentiation GO:0048762 87 0.057
system process GO:0003008 185 0.057
negative regulation of response to stimulus GO:0048585 104 0.056
Mouse
positive regulation of skeletal muscle tissue development GO:0048643 1 0.055
regulation of reproductive process GO:2000241 4 0.054
hemopoiesis GO:0030097 183 0.054
negative regulation of signaling GO:0023057 96 0.053
Mouse
striated muscle cell differentiation GO:0051146 129 0.053
mesoderm morphogenesis GO:0048332 51 0.053
endodermal cell fate specification GO:0001714 17 0.053
embryo development ending in birth or egg hatching GO:0009792 271 0.052
otic placode formation GO:0043049 23 0.052
gland development GO:0048732 143 0.052
regulation of locomotion GO:0040012 55 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.050
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.050
regulation of signaling GO:0023051 235 0.050
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.049
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.049
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.049
convergent extension involved in axis elongation GO:0060028 26 0.049
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.048
cardiac conduction system development GO:0003161 1 0.048
negative regulation of leukocyte differentiation GO:1902106 1 0.047
embryonic skeletal system morphogenesis GO:0048704 93 0.047
embryonic neurocranium morphogenesis GO:0048702 15 0.047
cell proliferation GO:0008283 80 0.047
Mouse
heart growth GO:0060419 7 0.047
floor plate development GO:0033504 15 0.047
cardiac atrium development GO:0003230 4 0.047
negative regulation of cell differentiation GO:0045596 46 0.046
post embryonic morphogenesis GO:0009886 4 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.045
negative regulation of rna biosynthetic process GO:1902679 45 0.045
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.044
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.044
Mouse
cardiac muscle cell differentiation GO:0055007 30 0.044
renal system development GO:0072001 94 0.043
mononuclear cell proliferation GO:0032943 1 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.043
Mouse
ear development GO:0043583 127 0.043
chemotaxis GO:0006935 104 0.043
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.042
hepatocyte proliferation GO:0072574 2 0.042
endoderm development GO:0007492 49 0.041
central nervous system neuron differentiation GO:0021953 74 0.041
response to lipid GO:0033993 60 0.041
Mouse
regulation of response to stimulus GO:0048583 269 0.041
Mouse
cardiogenic plate morphogenesis GO:0003142 1 0.041
cellular response to stress GO:0033554 62 0.040
negative regulation of metabolic process GO:0009892 86 0.040
Mouse
lipid storage GO:0019915 1 0.040
pronephros development GO:0048793 69 0.039
aorta development GO:0035904 4 0.039
negative regulation of cellular metabolic process GO:0031324 77 0.039
Mouse
neural tube development GO:0021915 62 0.039
cellular response to chemical stimulus GO:0070887 157 0.039
cell division GO:0051301 20 0.038
intermediate mesoderm development GO:0048389 2 0.038
kidney morphogenesis GO:0060993 15 0.038
protein metabolic process GO:0019538 183 0.038
regulation of epithelial cell proliferation GO:0050678 3 0.038
heterocycle biosynthetic process GO:0018130 215 0.038
Mouse
spinal cord development GO:0021510 46 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
Mouse
muscle organ development GO:0007517 101 0.036
positive regulation of nucleic acid templated transcription GO:1903508 57 0.036
regulation of cellular component organization GO:0051128 86 0.036
Mouse
regulation of cell motility GO:2000145 46 0.035
response to stress GO:0006950 263 0.035
dorsal convergence GO:0060030 14 0.035
ventricular cardiac muscle tissue development GO:0003229 3 0.034
specification of organ position GO:0010159 3 0.034
establishment of localization GO:0051234 244 0.034
response to organic cyclic compound GO:0014070 51 0.034
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.034
response to oxygen containing compound GO:1901700 55 0.033
Mouse
hypothalamus development GO:0021854 14 0.033
positive regulation of catabolic process GO:0009896 4 0.033
negative regulation of gene expression GO:0010629 65 0.032
Mouse
regulation of anterior head development GO:2000742 2 0.032
positive regulation of neuron migration GO:2001224 2 0.032
t cell differentiation in thymus GO:0033077 6 0.032
response to external stimulus GO:0009605 264 0.032
protein modification process GO:0036211 100 0.031
neural crest cell development GO:0014032 62 0.031
endocardial cushion development GO:0003197 6 0.031
hepatocyte differentiation GO:0070365 1 0.031
immune system development GO:0002520 191 0.031
response to fibroblast growth factor GO:0071774 22 0.030
cell migration to the midline involved in heart development GO:0003318 12 0.030
neural plate regionalization GO:0060897 10 0.030
hematopoietic progenitor cell differentiation GO:0002244 23 0.030
axonogenesis GO:0007409 152 0.030
axon extension GO:0048675 45 0.030
response to organic substance GO:0010033 153 0.029
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.029
Mouse
striated muscle cell proliferation GO:0014855 7 0.029
nephron morphogenesis GO:0072028 2 0.029
heart contraction GO:0060047 71 0.029
otic vesicle morphogenesis GO:0071600 34 0.029
regulation of cell proliferation GO:0042127 37 0.029
Mouse
skeletal muscle tissue development GO:0007519 67 0.029
negative regulation of biosynthetic process GO:0009890 55 0.028
Mouse
negative regulation of wnt signaling pathway GO:0030178 30 0.028
heart process GO:0003015 71 0.028
regulation of transcription dna templated GO:0006355 213 0.028
Mouse
hindbrain formation GO:0021576 3 0.028
specification of organ identity GO:0010092 2 0.028
nodal signaling pathway GO:0038092 7 0.027
Mouse
death GO:0016265 121 0.027
regulation of calcium ion transport GO:0051924 2 0.027
positive regulation of biological process GO:0048518 253 0.027
negative regulation of embryonic development GO:0045992 11 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.026
convergent extension involved in organogenesis GO:0060029 10 0.026
regulation of cellular response to growth factor stimulus GO:0090287 35 0.026
photoreceptor cell development GO:0042461 40 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
regulation of canonical wnt signaling pathway GO:0060828 34 0.026
neural tube patterning GO:0021532 33 0.026
canonical wnt signaling pathway GO:0060070 48 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
vasculogenesis GO:0001570 41 0.025
regulation of cardiac chamber formation GO:1901210 2 0.025
cell cell signaling GO:0007267 52 0.025
ventral spinal cord development GO:0021517 35 0.025
regulation of skeletal muscle tissue development GO:0048641 4 0.024
axis elongation GO:0003401 31 0.024
single organism metabolic process GO:0044710 217 0.024
astrocyte differentiation GO:0048708 1 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
behavior GO:0007610 74 0.024
anterior posterior axis specification embryo GO:0008595 5 0.024
sprouting angiogenesis GO:0002040 53 0.024
regulation of mesodermal cell fate specification GO:0042661 9 0.024
single organism biosynthetic process GO:0044711 71 0.024
positive regulation of endothelial cell differentiation GO:0045603 2 0.024
regulation of signal transduction GO:0009966 225 0.023
Mouse
homeostatic process GO:0042592 142 0.023
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.023
mesodermal cell fate specification GO:0007501 12 0.023
extraocular skeletal muscle development GO:0002074 3 0.023
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.023
negative regulation of muscle tissue development GO:1901862 2 0.023
cellular component assembly GO:0022607 170 0.023
Mouse
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.023
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.022
positive regulation of stem cell proliferation GO:2000648 1 0.022
protein complex biogenesis GO:0070271 30 0.022
Mouse
pancreas development GO:0031016 84 0.022
mesodermal cell differentiation GO:0048333 21 0.022
dorsal ventral axis specification GO:0009950 14 0.022
cellular component biogenesis GO:0044085 178 0.022
Mouse
endothelial cell fate commitment GO:0060839 3 0.022
somatic muscle development GO:0007525 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
gliogenesis GO:0042063 45 0.021
otic vesicle formation GO:0030916 27 0.021
regulation of epithelial to mesenchymal transition GO:0010717 3 0.021
photoreceptor cell differentiation GO:0046530 55 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.021
medial fin development GO:0033338 16 0.021
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.021
glial cell fate specification GO:0021780 4 0.021
cell fate specification GO:0001708 68 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
regulation of neuron migration GO:2001222 2 0.020
endodermal digestive tract morphogenesis GO:0061031 2 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
response to growth factor GO:0070848 39 0.020
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.019
regulation of gastrulation GO:0010470 24 0.019
cardiac muscle tissue regeneration GO:0061026 3 0.019
stem cell maintenance GO:0019827 4 0.019
trigeminal motor nucleus development GO:0021731 2 0.019
facial nucleus development GO:0021754 7 0.019
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.019
locomotory behavior GO:0007626 34 0.019
maintenance of location GO:0051235 4 0.019
regulation of mitotic cell cycle GO:0007346 25 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of embryonic development GO:0045995 47 0.019
sensory perception GO:0007600 39 0.019
programmed cell death GO:0012501 119 0.019
sensory epithelium regeneration GO:0070654 14 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.018
cell cycle GO:0007049 93 0.018
cell proliferation involved in heart morphogenesis GO:0061323 2 0.018
negative regulation of signal transduction GO:0009968 94 0.018
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.018
wnt signaling pathway involved in heart development GO:0003306 5 0.018
limbic system development GO:0021761 16 0.018
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.018
circulatory system process GO:0003013 87 0.018
neuron projection guidance GO:0097485 86 0.018
ectoderm formation GO:0001705 2 0.017
negative regulation of endodermal cell differentiation GO:1903225 8 0.017
organelle organization GO:0006996 227 0.017
appendage development GO:0048736 80 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
developmental induction GO:0031128 10 0.017
anterior head development GO:0097065 2 0.017
negative regulation of catabolic process GO:0009895 3 0.017
post anal tail morphogenesis GO:0036342 19 0.017
stem cell differentiation GO:0048863 117 0.016
regeneration GO:0031099 91 0.016
motor neuron axon guidance GO:0008045 23 0.016
regulation of heart growth GO:0060420 2 0.016
skeletal system development GO:0001501 181 0.016
lymphocyte proliferation GO:0046651 1 0.016
cell migration involved in heart development GO:0060973 22 0.016
left right pattern formation GO:0060972 19 0.016
lipid metabolic process GO:0006629 52 0.016
negative regulation of nucleic acid templated transcription GO:1903507 45 0.016
Mouse
larval development GO:0002164 2 0.016
striated muscle cell development GO:0055002 108 0.016
endocardial cushion morphogenesis GO:0003203 3 0.015
macromolecular complex assembly GO:0065003 35 0.015
Mouse
pons development GO:0021548 11 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
dorsal aorta morphogenesis GO:0035912 3 0.015
morphogenesis of a branching epithelium GO:0061138 16 0.015
retinal cell programmed cell death GO:0046666 2 0.015
neuron projection morphogenesis GO:0048812 161 0.014
negative regulation of cell communication GO:0010648 96 0.014
Mouse
morphogenesis of an epithelial fold GO:0060571 1 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
embryonic foregut morphogenesis GO:0048617 1 0.014
otic vesicle development GO:0071599 42 0.014
organ growth GO:0035265 12 0.014
negative chemotaxis GO:0050919 1 0.014
single organism reproductive process GO:0044702 40 0.014
regulation of binding GO:0051098 3 0.014
reproduction GO:0000003 40 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
transport GO:0006810 220 0.014

lft2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
acrocephalosyndactylia DOID:12960 0 0.014
dysostosis DOID:1934 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
synostosis DOID:11971 0 0.014