Danio rerio

3 known processes

smyhc1l

slow myosin heavy chain 1, like

(Aliases: smyhc1,myhc5)

smyhc1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.728
nitric oxide metabolic process GO:0046209 2 0.648
larval development GO:0002164 2 0.569
regulation of muscle contraction GO:0006937 3 0.507
somatic muscle development GO:0007525 4 0.462
post embryonic organ development GO:0048569 4 0.428
sarcomere organization GO:0045214 26 0.418
ventricular cardiac muscle tissue development GO:0003229 3 0.408
reactive nitrogen species metabolic process GO:2001057 0 0.383
mitochondrion organization GO:0007005 4 0.379
cell projection organization GO:0030030 284 0.365
patterning of blood vessels GO:0001569 15 0.363
skeletal myofibril assembly GO:0014866 7 0.345
lipid storage GO:0019915 1 0.345
heart development GO:0007507 313 0.333
blood vessel development GO:0001568 246 0.326
nitric oxide biosynthetic process GO:0006809 2 0.313
actomyosin structure organization GO:0031032 53 0.308
blood vessel morphogenesis GO:0048514 216 0.299
cellular component movement GO:0006928 335 0.296
myosin filament assembly GO:0031034 6 0.288
venous blood vessel development GO:0060841 9 0.285
blood circulation GO:0008015 87 0.256
vasculature development GO:0001944 278 0.250
striated muscle myosin thick filament assembly GO:0071688 6 0.248
cellular component morphogenesis GO:0032989 336 0.241
striated muscle cell development GO:0055002 108 0.241
signal transduction GO:0007165 455 0.238
heart process GO:0003015 71 0.235
actin cytoskeleton organization GO:0030036 63 0.234
organelle assembly GO:0070925 110 0.223
myofibril assembly GO:0030239 48 0.210
heart contraction GO:0060047 71 0.209
muscle cell development GO:0055001 115 0.209
cellular component assembly involved in morphogenesis GO:0010927 107 0.202
actin filament based process GO:0030029 64 0.202
striated muscle cell differentiation GO:0051146 129 0.196
maintenance of location GO:0051235 4 0.196
lymphoid lineage cell migration GO:0097534 4 0.196
cardiac muscle tissue morphogenesis GO:0055008 7 0.188
locomotion GO:0040011 313 0.188
heart morphogenesis GO:0003007 156 0.187
localization of cell GO:0051674 244 0.184
cardiac ventricle morphogenesis GO:0003208 7 0.183
neuron differentiation GO:0030182 353 0.180
angiogenesis GO:0001525 158 0.177
cell migration GO:0016477 237 0.176
immune system development GO:0002520 191 0.172
purine nucleoside monophosphate catabolic process GO:0009128 4 0.172
cell motility GO:0048870 244 0.168
skeletal muscle thin filament assembly GO:0030240 4 0.168
stem cell differentiation GO:0048863 117 0.166
myosin filament organization GO:0031033 6 0.161
venous blood vessel morphogenesis GO:0048845 3 0.156
morphogenesis of an epithelium GO:0002009 333 0.155
ribonucleoside monophosphate catabolic process GO:0009158 4 0.154
hematopoietic progenitor cell differentiation GO:0002244 23 0.153
muscle tissue development GO:0060537 110 0.153
tube morphogenesis GO:0035239 349 0.152
neuron development GO:0048666 262 0.145
regulation of response to stimulus GO:0048583 269 0.145
hematopoietic stem cell differentiation GO:0060218 20 0.144
cardiac muscle tissue development GO:0048738 48 0.141
axon development GO:0061564 166 0.137
circulatory system process GO:0003013 87 0.132
axonal fasciculation GO:0007413 11 0.131
multicellular organismal movement GO:0050879 8 0.130
organelle organization GO:0006996 227 0.129
mesoderm development GO:0007498 88 0.125
artery development GO:0060840 22 0.123
cellular nitrogen compound biosynthetic process GO:0044271 218 0.123
single organism organelle organization GO:1902589 199 0.122
muscle cell differentiation GO:0042692 139 0.119
regulation of system process GO:0044057 40 0.117
cardiac ventricle development GO:0003231 9 0.116
reactive oxygen species metabolic process GO:0072593 6 0.115
biosynthetic process GO:0009058 294 0.115
regulation of blood circulation GO:1903522 32 0.114
immune system process GO:0002376 241 0.114
cardiac chamber morphogenesis GO:0003206 12 0.111
hematopoietic or lymphoid organ development GO:0048534 191 0.111
hemopoiesis GO:0030097 183 0.108
regulation of heart contraction GO:0008016 32 0.107
regulation of signal transduction GO:0009966 225 0.105
regulation of striated muscle contraction GO:0006942 2 0.103
cardiac chamber development GO:0003205 19 0.102
muscle organ morphogenesis GO:0048644 8 0.100
pronephros development GO:0048793 69 0.096
intracellular signal transduction GO:0035556 85 0.094
cellular component assembly GO:0022607 170 0.094
epithelial tube morphogenesis GO:0060562 148 0.091
cytoskeleton organization GO:0007010 96 0.088
muscle structure development GO:0061061 196 0.087
cellular biosynthetic process GO:0044249 286 0.086
neuron projection development GO:0031175 180 0.084
protein localization to nucleus GO:0034504 3 0.080
developmental growth GO:0048589 166 0.077
ion homeostasis GO:0050801 41 0.076
regulation of primary metabolic process GO:0080090 311 0.076
striated muscle tissue development GO:0014706 110 0.076
urogenital system development GO:0001655 97 0.074
skeletal muscle contraction GO:0003009 5 0.073
regulation of biological quality GO:0065008 263 0.073
lymphoid lineage cell migration into thymus GO:0097535 4 0.071
digestive system development GO:0055123 289 0.071
regulation of multicellular organismal process GO:0051239 277 0.071
regionalization GO:0003002 274 0.068
small molecule metabolic process GO:0044281 77 0.067
protein metabolic process GO:0019538 183 0.065
cellular cation homeostasis GO:0030003 17 0.063
anatomical structure homeostasis GO:0060249 36 0.063
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
cellular ion homeostasis GO:0006873 17 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.060
cellular aromatic compound metabolic process GO:0006725 295 0.060
system process GO:0003008 185 0.060
divalent inorganic cation homeostasis GO:0072507 22 0.059
regulation of protein import into nucleus GO:0042306 2 0.059
establishment of localization GO:0051234 244 0.059
homeostatic process GO:0042592 142 0.059
regulation of nitric oxide mediated signal transduction GO:0010749 1 0.057
voluntary skeletal muscle contraction GO:0003010 4 0.057
macromolecular complex subunit organization GO:0043933 74 0.056
renal system development GO:0072001 94 0.054
regulation of intracellular signal transduction GO:1902531 57 0.054
atp catabolic process GO:0006200 4 0.053
cell projection morphogenesis GO:0048858 244 0.053
actin filament organization GO:0007015 15 0.053
transport GO:0006810 220 0.052
ameboidal type cell migration GO:0001667 143 0.051
cardiac muscle cell differentiation GO:0055007 30 0.050
regulation of transcription dna templated GO:0006355 213 0.049
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.049
nucleoside monophosphate catabolic process GO:0009125 4 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.046
regulation of metabolic process GO:0019222 359 0.046
regulation of signaling GO:0023051 235 0.046
regulation of purine nucleotide catabolic process GO:0033121 2 0.046
nucleic acid templated transcription GO:0097659 181 0.045
regulation of protein targeting GO:1903533 2 0.045
muscle organ development GO:0007517 101 0.045
neuron projection morphogenesis GO:0048812 161 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
regulation of protein transport GO:0051223 3 0.042
negative chemotaxis GO:0050919 1 0.041
nucleobase containing compound metabolic process GO:0006139 274 0.041
regulation of nucleoside metabolic process GO:0009118 2 0.041
metal ion homeostasis GO:0055065 26 0.040
heterocycle metabolic process GO:0046483 290 0.040
morphogenesis of a branching structure GO:0001763 21 0.040
organic substance biosynthetic process GO:1901576 289 0.040
generation of neurons GO:0048699 385 0.040
regulation of nucleotide catabolic process GO:0030811 2 0.039
outflow tract morphogenesis GO:0003151 1 0.039
regulation of cell communication GO:0010646 232 0.038
embryonic heart tube development GO:0035050 133 0.038
chemical homeostasis GO:0048878 49 0.038
cell part morphogenesis GO:0032990 246 0.038
kidney development GO:0001822 92 0.038
multi organism process GO:0051704 134 0.038
response to chemical GO:0042221 320 0.038
morphogenesis of a branching epithelium GO:0061138 16 0.038
segmentation GO:0035282 97 0.037
regulation of protein localization to nucleus GO:1900180 2 0.036
protein complex subunit organization GO:0071822 46 0.036
multicellular organism growth GO:0035264 4 0.036
protein import GO:0017038 3 0.035
cation homeostasis GO:0055080 33 0.035
muscle system process GO:0003012 20 0.034
axon guidance GO:0007411 86 0.034
nitric oxide mediated signal transduction GO:0007263 2 0.034
muscle cell cellular homeostasis GO:0046716 5 0.034
muscle contraction GO:0006936 18 0.034
actin filament based movement GO:0030048 1 0.033
nuclear import GO:0051170 3 0.033
sexual reproduction GO:0019953 36 0.033
macromolecule catabolic process GO:0009057 15 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
cardiocyte differentiation GO:0035051 44 0.033
cell morphogenesis GO:0000902 289 0.032
inositol lipid mediated signaling GO:0048017 2 0.032
digestive tract development GO:0048565 265 0.032
cellular protein catabolic process GO:0044257 4 0.031
neuron recognition GO:0008038 18 0.031
response to drug GO:0042493 3 0.031
cell surface receptor signaling pathway GO:0007166 325 0.030
macromolecular complex assembly GO:0065003 35 0.030
nuclear transport GO:0051169 4 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
cognition GO:0050890 1 0.030
muscle tissue morphogenesis GO:0060415 7 0.029
cell recognition GO:0008037 19 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
single organism metabolic process GO:0044710 217 0.028
negative regulation of biological process GO:0048519 304 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
meiotic cell cycle process GO:1903046 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
sympathetic nervous system development GO:0048485 3 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
central nervous system development GO:0007417 387 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
death GO:0016265 121 0.026
cellular macromolecular complex assembly GO:0034622 24 0.026
protein targeting to nucleus GO:0044744 3 0.026
cardiac muscle cell development GO:0055013 20 0.025
cellular component biogenesis GO:0044085 178 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
cytokinesis GO:0000910 3 0.024
regulation of blood pressure GO:0008217 1 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
motor neuron axon guidance GO:0008045 23 0.023
axonogenesis GO:0007409 152 0.023
twitch skeletal muscle contraction GO:0014721 4 0.023
single organism reproductive process GO:0044702 40 0.023
anatomical structure arrangement GO:0048532 2 0.023
cytoskeleton dependent cytokinesis GO:0061640 3 0.022
positive regulation of transport GO:0051050 2 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
somite development GO:0061053 96 0.022
regulation of circadian rhythm GO:0042752 4 0.022
aging GO:0007568 2 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
branching morphogenesis of an epithelial tube GO:0048754 15 0.022
rna metabolic process GO:0016070 219 0.022
apoptotic process GO:0006915 116 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
tissue remodeling GO:0048771 4 0.021
negative regulation of sequestering of calcium ion GO:0051283 4 0.021
regulation of metal ion transport GO:0010959 4 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of localization GO:0032879 104 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
cardiac cell development GO:0055006 21 0.020
facial nerve morphogenesis GO:0021610 1 0.020
regulation of apoptotic process GO:0042981 98 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
response to alkaloid GO:0043279 2 0.020
female gamete generation GO:0007292 14 0.020
regulation of protein complex disassembly GO:0043244 1 0.020
gene expression GO:0010467 252 0.020
chemotaxis GO:0006935 104 0.020
catabolic process GO:0009056 32 0.019
phosphorus metabolic process GO:0006793 109 0.019
cytokinetic process GO:0032506 2 0.019
regulation of transporter activity GO:0032409 2 0.019
epithelium migration GO:0090132 25 0.019
cellular homeostasis GO:0019725 26 0.019
cellular metal ion homeostasis GO:0006875 16 0.019
convergent extension GO:0060026 118 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
digestive tract morphogenesis GO:0048546 231 0.018
rna biosynthetic process GO:0032774 181 0.018
response to stress GO:0006950 263 0.018
meiotic nuclear division GO:0007126 4 0.018
regulation of organelle assembly GO:1902115 4 0.018
mesenchyme development GO:0060485 127 0.018
protein depolymerization GO:0051261 1 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
head development GO:0060322 303 0.017
cell cycle g2 m phase transition GO:0044839 4 0.017
multicellular organism reproduction GO:0032504 35 0.017
bmp signaling pathway GO:0030509 52 0.017
meiotic chromosome segregation GO:0045132 3 0.017
striated muscle contraction GO:0006941 12 0.017
somitogenesis GO:0001756 87 0.017
nucleic acid metabolic process GO:0090304 244 0.017
positive regulation of epithelial cell migration GO:0010634 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
negative regulation of axon guidance GO:1902668 1 0.016
cell cycle GO:0007049 93 0.016
stem cell maintenance GO:0019827 4 0.016
protein dephosphorylation GO:0006470 3 0.016
regulation of growth GO:0040008 42 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
neural crest cell development GO:0014032 62 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
negative regulation of chemotaxis GO:0050922 4 0.016
protein complex assembly GO:0006461 30 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
gamete generation GO:0007276 33 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
adult behavior GO:0030534 2 0.016
cellular response to external stimulus GO:0071496 2 0.016
protein complex biogenesis GO:0070271 30 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
protein complex disassembly GO:0043241 1 0.015
taxis GO:0042330 109 0.015
response to external stimulus GO:0009605 264 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
macromolecule localization GO:0033036 54 0.015
organic acid metabolic process GO:0006082 31 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
facial nerve development GO:0021561 3 0.014
protein import into nucleus GO:0006606 3 0.014
programmed cell death GO:0012501 119 0.014
regulation of gene expression GO:0010468 265 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of axon extension GO:0030516 24 0.014
oxoacid metabolic process GO:0043436 31 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
gastrulation GO:0007369 208 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
response to oxygen containing compound GO:1901700 55 0.014
regulation of endothelial cell proliferation GO:0001936 1 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
response to monosaccharide GO:0034284 3 0.014
organic substance catabolic process GO:1901575 28 0.014
amine metabolic process GO:0009308 2 0.014
neuron projection guidance GO:0097485 86 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
regulation of developmental process GO:0050793 247 0.014
actin mediated cell contraction GO:0070252 1 0.014
growth GO:0040007 174 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
regulation of chemotaxis GO:0050920 18 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
positive regulation of protein kinase b signaling GO:0051897 1 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
endothelial cell migration GO:0043542 19 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
regulation of mrna processing GO:0050684 3 0.013
cardiac atrium development GO:0003230 4 0.013
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
membrane fusion GO:0061025 2 0.013
behavior GO:0007610 74 0.013
embryonic pattern specification GO:0009880 44 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
organism emergence from protective structure GO:0071684 4 0.013
single organism membrane fusion GO:0044801 2 0.013
reproduction GO:0000003 40 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
regulation of nucleotide metabolic process GO:0006140 17 0.013
positive regulation of cytokine production GO:0001819 2 0.013
response to uv GO:0009411 3 0.013
heart looping GO:0001947 94 0.013
cellular response to hypoxia GO:0071456 1 0.013
regulation of molecular function GO:0065009 70 0.012
macromolecular complex disassembly GO:0032984 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of cytokine production GO:0001817 3 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
autophagy GO:0006914 4 0.012
post embryonic morphogenesis GO:0009886 4 0.012
response to organic substance GO:0010033 153 0.012
wnt signaling pathway GO:0016055 80 0.012
regulation of muscle system process GO:0090257 5 0.012
sprouting angiogenesis GO:0002040 53 0.012
regulation of protein catabolic process GO:0042176 1 0.012
brain development GO:0007420 293 0.012
regulation of reproductive process GO:2000241 4 0.012
gtp catabolic process GO:0006184 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
exocytosis GO:0006887 1 0.012
cell death GO:0008219 121 0.012
positive regulation of endothelial cell migration GO:0010595 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.012
cellular protein complex assembly GO:0043623 19 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
rna modification GO:0009451 2 0.012
regulation of developmental growth GO:0048638 38 0.012
positive regulation of cell activation GO:0050867 1 0.012
gland development GO:0048732 143 0.012
embryonic organ development GO:0048568 381 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.011
branchiomotor neuron axon guidance GO:0021785 1 0.011
single organism cellular localization GO:1902580 46 0.011
regulation of cell projection organization GO:0031344 44 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
appendage development GO:0048736 80 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
peptide transport GO:0015833 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
locomotor rhythm GO:0045475 3 0.011
membrane invagination GO:0010324 1 0.011
cardiac atrium morphogenesis GO:0003209 2 0.011
developmental programmed cell death GO:0010623 4 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
sequestering of calcium ion GO:0051208 3 0.011
cellular component disassembly GO:0022411 1 0.011
calcium ion homeostasis GO:0055074 19 0.011
positive regulation of reproductive process GO:2000243 2 0.011
cellular response to oxygen levels GO:0071453 1 0.011
epithelial cell migration GO:0010631 25 0.011
multi organism reproductive process GO:0044703 36 0.011
regulation of gtpase activity GO:0043087 2 0.010
neuron projection extension GO:1990138 45 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
neuroblast proliferation GO:0007405 2 0.010
autonomic nervous system development GO:0048483 19 0.010
cellular localization GO:0051641 97 0.010
cellular protein complex disassembly GO:0043624 1 0.010
tissue migration GO:0090130 37 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
positive regulation of catabolic process GO:0009896 4 0.010
phagocytosis GO:0006909 3 0.010
ribonucleotide metabolic process GO:0009259 27 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of cellular biosynthetic process GO:0031326 245 0.010
sequestering of metal ion GO:0051238 3 0.010
hormone secretion GO:0046879 2 0.010
regulation of cell development GO:0060284 100 0.010
peripheral nervous system neuron differentiation GO:0048934 28 0.010

smyhc1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.098
muscular disease DOID:0080000 0 0.041
musculoskeletal system disease DOID:17 0 0.041
muscle tissue disease DOID:66 0 0.034
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013