Danio rerio

0 known processes

cspg4

chondroitin sulfate proteoglycan 4

cspg4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.152
signal transduction GO:0007165 455 0.103
larval development GO:0002164 2 0.102
embryonic organ development GO:0048568 381 0.088
cell surface receptor signaling pathway GO:0007166 325 0.083
regulation of response to stimulus GO:0048583 269 0.077
cell motility GO:0048870 244 0.066
eye development GO:0001654 277 0.058
positive regulation of transport GO:0051050 2 0.057
regulation of signal transduction GO:0009966 225 0.056
aging GO:0007568 2 0.055
localization of cell GO:0051674 244 0.054
cellular response to external stimulus GO:0071496 2 0.049
regulation of signaling GO:0023051 235 0.048
morphogenesis of an epithelium GO:0002009 333 0.047
tube morphogenesis GO:0035239 349 0.047
vasculature development GO:0001944 278 0.046
digestive system development GO:0055123 289 0.045
camera type eye development GO:0043010 222 0.042
cell substrate adhesion GO:0031589 4 0.042
muscle structure development GO:0061061 196 0.040
positive regulation of cell cycle GO:0045787 3 0.039
maintenance of location GO:0051235 4 0.039
sensory perception of pain GO:0019233 1 0.039
g protein coupled receptor signaling pathway GO:0007186 74 0.038
cell migration GO:0016477 237 0.038
positive regulation of inflammatory response GO:0050729 1 0.037
skeletal muscle organ development GO:0060538 78 0.036
cellular component movement GO:0006928 335 0.036
negative regulation of cellular process GO:0048523 283 0.036
regulation of cell communication GO:0010646 232 0.035
cell morphogenesis GO:0000902 289 0.035
stem cell maintenance GO:0019827 4 0.033
lateral inhibition GO:0046331 1 0.033
lipid storage GO:0019915 1 0.033
regulation of sodium ion transport GO:0002028 2 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
organelle organization GO:0006996 227 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
multicellular organism growth GO:0035264 4 0.030
positive regulation of catabolic process GO:0009896 4 0.030
nucleic acid metabolic process GO:0090304 244 0.029
smooth muscle contraction GO:0006939 2 0.029
regulation of protein catabolic process GO:0042176 1 0.029
cell projection organization GO:0030030 284 0.029
cellular protein catabolic process GO:0044257 4 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
system process GO:0003008 185 0.028
enzyme linked receptor protein signaling pathway GO:0007167 106 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
cellular component morphogenesis GO:0032989 336 0.027
organic substance biosynthetic process GO:1901576 289 0.027
blood vessel development GO:0001568 246 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
actin polymerization or depolymerization GO:0008154 2 0.026
establishment of localization GO:0051234 244 0.026
regulation of epithelial cell proliferation GO:0050678 3 0.026
renal system development GO:0072001 94 0.026
cellular macromolecule metabolic process GO:0044260 391 0.025
negative regulation of biological process GO:0048519 304 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
angiogenesis GO:0001525 158 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
regulation of inflammatory response GO:0050727 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
response to organic substance GO:0010033 153 0.024
neuron development GO:0048666 262 0.024
cyclic purine nucleotide metabolic process GO:0052652 18 0.024
regulation of protein complex assembly GO:0043254 3 0.024
meiotic nuclear division GO:0007126 4 0.024
female sex differentiation GO:0046660 4 0.023
neuromast development GO:0048884 46 0.023
regulation of metal ion transport GO:0010959 4 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
biosynthetic process GO:0009058 294 0.022
heart development GO:0007507 313 0.022
phagocytosis GO:0006909 3 0.022
embryonic heart tube development GO:0035050 133 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
phosphorus metabolic process GO:0006793 109 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
endosomal transport GO:0016197 2 0.022
retina development in camera type eye GO:0060041 146 0.022
cellular response to nutrient levels GO:0031669 2 0.022
regulation of muscle contraction GO:0006937 3 0.021
regulation of gene expression GO:0010468 265 0.021
regulation of synapse organization GO:0050807 3 0.021
cellular response to starvation GO:0009267 1 0.021
muscle organ development GO:0007517 101 0.021
neutrophil migration GO:1990266 10 0.021
digestive tract morphogenesis GO:0048546 231 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
response to wounding GO:0009611 116 0.021
negative regulation of signal transduction GO:0009968 94 0.021
regulation of tube size GO:0035150 2 0.021
urogenital system development GO:0001655 97 0.021
stem cell proliferation GO:0072089 4 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
cellular biosynthetic process GO:0044249 286 0.020
protein localization to plasma membrane GO:0072659 1 0.020
regulation of localization GO:0032879 104 0.020
blood vessel morphogenesis GO:0048514 216 0.020
regulation of cytokine production GO:0001817 3 0.020
amine metabolic process GO:0009308 2 0.020
generation of neurons GO:0048699 385 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
mesenchyme development GO:0060485 127 0.020
protein polymerization GO:0051258 4 0.020
immune system process GO:0002376 241 0.020
taxis GO:0042330 109 0.020
transcription dna templated GO:0006351 181 0.020
heterocycle biosynthetic process GO:0018130 215 0.019
gastrulation GO:0007369 208 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
establishment of endothelial barrier GO:0061028 3 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
autophagy GO:0006914 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
stem cell differentiation GO:0048863 117 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
sequestering of metal ion GO:0051238 3 0.019
nuclear transport GO:0051169 4 0.019
hemopoiesis GO:0030097 183 0.018
regulation of binding GO:0051098 3 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
regulation of biosynthetic process GO:0009889 250 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
embryonic skeletal system development GO:0048706 97 0.018
adult behavior GO:0030534 2 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
regulation of protein transport GO:0051223 3 0.018
wnt signaling pathway GO:0016055 80 0.018
skeletal system development GO:0001501 181 0.017
immune system development GO:0002520 191 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
lateral line development GO:0048882 66 0.017
response to external stimulus GO:0009605 264 0.017
protein localization to nucleus GO:0034504 3 0.017
single organism organelle organization GO:1902589 199 0.017
response to chemical GO:0042221 320 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
cell projection morphogenesis GO:0048858 244 0.017
digestive tract development GO:0048565 265 0.017
wound healing GO:0042060 90 0.017
nucleic acid templated transcription GO:0097659 181 0.017
cellular response to radiation GO:0071478 4 0.017
brain development GO:0007420 293 0.016
regulation of blood vessel size GO:0050880 2 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
regulation of locomotion GO:0040012 55 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
rna metabolic process GO:0016070 219 0.016
regulation of developmental process GO:0050793 247 0.016
protein complex disassembly GO:0043241 1 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
macromolecular complex disassembly GO:0032984 1 0.016
rna localization GO:0006403 4 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
gtp catabolic process GO:0006184 2 0.016
single organism metabolic process GO:0044710 217 0.016
sensory system development GO:0048880 76 0.016
locomotion GO:0040011 313 0.016
cellular ketone metabolic process GO:0042180 11 0.016
monovalent inorganic cation transport GO:0015672 42 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.016
kidney development GO:0001822 92 0.015
protein acetylation GO:0006473 2 0.015
protein metabolic process GO:0019538 183 0.015
protein acylation GO:0043543 3 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
olfactory lobe development GO:0021988 4 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
sensory organ morphogenesis GO:0090596 200 0.015
cellular response to organic substance GO:0071310 105 0.015
regulation of metabolic process GO:0019222 359 0.015
phototransduction GO:0007602 2 0.015
muscle cell differentiation GO:0042692 139 0.015
negative regulation of signaling GO:0023057 96 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
locomotor rhythm GO:0045475 3 0.015
response to drug GO:0042493 3 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
cellular amine metabolic process GO:0044106 2 0.015
energy reserve metabolic process GO:0006112 2 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.014
membrane fusion GO:0061025 2 0.014
stem cell development GO:0048864 82 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
epithelial cell differentiation GO:0030855 116 0.014
regulation of protein polymerization GO:0032271 2 0.014
head development GO:0060322 303 0.014
determination of bilateral symmetry GO:0009855 204 0.014
canonical wnt signaling pathway GO:0060070 48 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of protein binding GO:0043393 3 0.014
endocrine system development GO:0035270 65 0.014
heart morphogenesis GO:0003007 156 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of cell activation GO:0050865 1 0.014
sequestering of calcium ion GO:0051208 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
rna biosynthetic process GO:0032774 181 0.014
gene expression GO:0010467 252 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
single organism transport GO:0044765 206 0.014
response to amino acid GO:0043200 2 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
chordate embryonic development GO:0043009 271 0.014
neuron differentiation GO:0030182 353 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
cognition GO:0050890 1 0.014
tissue remodeling GO:0048771 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
eye morphogenesis GO:0048592 144 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
mitochondrion organization GO:0007005 4 0.013
hormone secretion GO:0046879 2 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
protein import GO:0017038 3 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
neuron projection morphogenesis GO:0048812 161 0.013
synaptic vesicle localization GO:0097479 1 0.013
protein import into nucleus GO:0006606 3 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
response to alkaloid GO:0043279 2 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
exocytosis GO:0006887 1 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
protein heterooligomerization GO:0051291 1 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
transport GO:0006810 220 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
determination of left right symmetry GO:0007368 179 0.013
specification of symmetry GO:0009799 204 0.013
compound eye development GO:0048749 2 0.013
synaptic vesicle transport GO:0048489 1 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
regulation of rna metabolic process GO:0051252 224 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
adherens junction organization GO:0034332 4 0.013
response to stress GO:0006950 263 0.013
ovulation cycle process GO:0022602 2 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
regulation of cell migration GO:0030334 40 0.013
neurotransmitter transport GO:0006836 2 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
somatic muscle development GO:0007525 4 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of dendrite development GO:0050773 3 0.013
response to topologically incorrect protein GO:0035966 2 0.013
response to uv GO:0009411 3 0.013
organic acid metabolic process GO:0006082 31 0.012
cell cycle arrest GO:0007050 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
pericardium development GO:0060039 1 0.012
programmed cell death GO:0012501 119 0.012
positive regulation of biological process GO:0048518 253 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
regulation of cellular component movement GO:0051270 55 0.012
myeloid cell differentiation GO:0030099 86 0.012
axon development GO:0061564 166 0.012
stem cell division GO:0017145 1 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
amino acid transport GO:0006865 2 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
macroautophagy GO:0016236 1 0.012
blood circulation GO:0008015 87 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
positive regulation of camp metabolic process GO:0030816 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
heterocycle metabolic process GO:0046483 290 0.012
positive regulation of cytokine production GO:0001819 2 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
small molecule catabolic process GO:0044282 3 0.012
homeostatic process GO:0042592 142 0.012
mononuclear cell proliferation GO:0032943 1 0.012
neural crest cell development GO:0014032 62 0.012
atp catabolic process GO:0006200 4 0.012
mesenchymal cell development GO:0014031 78 0.012
response to carbohydrate GO:0009743 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
organelle assembly GO:0070925 110 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of primary metabolic process GO:0080090 311 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
single organism membrane fusion GO:0044801 2 0.012
erythrocyte homeostasis GO:0034101 55 0.012
carbohydrate homeostasis GO:0033500 1 0.012
small molecule metabolic process GO:0044281 77 0.012
female gonad development GO:0008585 4 0.012
multicellular organismal response to stress GO:0033555 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
intracellular mrna localization GO:0008298 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
positive regulation of secretion GO:0051047 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
hormone transport GO:0009914 2 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of protein targeting GO:1903533 2 0.011
positive regulation of cell activation GO:0050867 1 0.011
regulation of growth rate GO:0040009 1 0.011
response to vitamin GO:0033273 3 0.011
membrane invagination GO:0010324 1 0.011
gtp metabolic process GO:0046039 4 0.011
response to corticosteroid GO:0031960 1 0.011
myeloid leukocyte migration GO:0097529 12 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
single organism localization GO:1902578 225 0.011
olfactory bulb development GO:0021772 4 0.011
positive regulation of neutrophil migration GO:1902624 0 0.011
protein homooligomerization GO:0051260 3 0.011
centrosome organization GO:0051297 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
ribonucleotide biosynthetic process GO:0009260 20 0.011
regulation of calcium ion transport GO:0051924 2 0.011
regulation of cell projection assembly GO:0060491 4 0.011
regulation of protein depolymerization GO:1901879 1 0.011
response to decreased oxygen levels GO:0036293 25 0.011
apoptotic process GO:0006915 116 0.011
negative regulation of metabolic process GO:0009892 86 0.011
oxoacid metabolic process GO:0043436 31 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
organism emergence from protective structure GO:0071684 4 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
dna templated transcription elongation GO:0006354 3 0.011
regulation of cell shape GO:0008360 1 0.010
cell part morphogenesis GO:0032990 246 0.010
regulation of autophagy GO:0010506 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
lymphocyte proliferation GO:0046651 1 0.010
positive regulation of immune effector process GO:0002699 3 0.010
notch signaling pathway GO:0007219 35 0.010
heart contraction GO:0060047 71 0.010
leukocyte proliferation GO:0070661 1 0.010
regulation of cell motility GO:2000145 46 0.010
neuroblast proliferation GO:0007405 2 0.010
ovulation cycle GO:0042698 2 0.010
protein dephosphorylation GO:0006470 3 0.010
regulation of biological quality GO:0065008 263 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
protein secretion GO:0009306 1 0.010
meiotic chromosome segregation GO:0045132 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
lateral line system development GO:0048925 76 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
multi organism process GO:0051704 134 0.010
regulation of organ growth GO:0046620 3 0.010
neural crest cell differentiation GO:0014033 72 0.010
cytokinesis GO:0000910 3 0.010
ion transport GO:0006811 114 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
cartilage development GO:0051216 96 0.010
peptide transport GO:0015833 1 0.010
regulation of jak stat cascade GO:0046425 3 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010

cspg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.096
musculoskeletal system disease DOID:17 0 0.039
myopathy DOID:423 0 0.036
muscular disease DOID:0080000 0 0.036
muscle tissue disease DOID:66 0 0.036
nervous system disease DOID:863 0 0.020
cardiovascular system disease DOID:1287 0 0.017
heart disease DOID:114 0 0.016
cardiomyopathy DOID:0050700 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.011