Danio rerio

0 known processes

zgc:113143

zgc:113143

zgc:113143 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
recombinational repair GO:0000725 1 0.316
Human
double strand break repair via homologous recombination GO:0000724 1 0.214
Human
organic cyclic compound metabolic process GO:1901360 301 0.210
Human
meiosis i GO:0007127 1 0.184
cellular aromatic compound metabolic process GO:0006725 295 0.167
Human
meiotic nuclear division GO:0007126 4 0.164
negative regulation of nuclear division GO:0051784 3 0.134
cellular macromolecule biosynthetic process GO:0034645 224 0.123
Human
nitrogen compound metabolic process GO:0006807 319 0.122
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.113
Human
rna biosynthetic process GO:0032774 181 0.099
Human
cell part morphogenesis GO:0032990 246 0.094
protein metabolic process GO:0019538 183 0.093
regulation of multicellular organism growth GO:0040014 4 0.093
regulation of transcription dna templated GO:0006355 213 0.086
Human
regulation of rna metabolic process GO:0051252 224 0.086
Human
regulation of cellular biosynthetic process GO:0031326 245 0.083
Human
positive regulation of cell cycle GO:0045787 3 0.074
cellular component biogenesis GO:0044085 178 0.073
transcription dna templated GO:0006351 181 0.072
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.072
Human
telomere organization GO:0032200 1 0.067
cellular response to dna damage stimulus GO:0006974 24 0.066
Human
cellular component assembly GO:0022607 170 0.066
single organism organelle organization GO:1902589 199 0.064
heterocycle biosynthetic process GO:0018130 215 0.064
Human
response to stress GO:0006950 263 0.063
Human
regulation of macromolecule metabolic process GO:0060255 317 0.063
Human
multicellular organism growth GO:0035264 4 0.062
sister chromatid cohesion GO:0007062 2 0.061
cilium organization GO:0044782 71 0.060
ribonucleoside monophosphate catabolic process GO:0009158 4 0.060
organelle organization GO:0006996 227 0.059
positive regulation of protein complex assembly GO:0031334 2 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.056
Human
cell cycle g2 m phase transition GO:0044839 4 0.056
regulation of rna biosynthetic process GO:2001141 213 0.055
Human
meiotic cell cycle process GO:1903046 3 0.055
regulation of macromolecule biosynthetic process GO:0010556 225 0.055
Human
g2 m transition of mitotic cell cycle GO:0000086 4 0.054
immunoglobulin mediated immune response GO:0016064 3 0.053
regulation of gene expression GO:0010468 265 0.053
Human
atp catabolic process GO:0006200 4 0.051
signal transduction GO:0007165 455 0.051
cellular component movement GO:0006928 335 0.050
organelle assembly GO:0070925 110 0.050
cellular macromolecule metabolic process GO:0044260 391 0.049
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.049
localization of cell GO:0051674 244 0.048
double strand break repair GO:0006302 3 0.047
Human
purine nucleoside monophosphate catabolic process GO:0009128 4 0.047
cell substrate adhesion GO:0031589 4 0.047
regulation of metabolic process GO:0019222 359 0.045
Human
negative regulation of biological process GO:0048519 304 0.045
Human
nucleobase containing compound metabolic process GO:0006139 274 0.044
Human
cell projection morphogenesis GO:0048858 244 0.043
nucleic acid templated transcription GO:0097659 181 0.042
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.042
Human
sensory organ development GO:0007423 393 0.042
heterocycle metabolic process GO:0046483 290 0.041
Human
mitotic dna damage checkpoint GO:0044773 4 0.040
regulation of cellular metabolic process GO:0031323 320 0.040
Human
immune system process GO:0002376 241 0.040
cellular component assembly involved in morphogenesis GO:0010927 107 0.039
larval development GO:0002164 2 0.039
cell migration GO:0016477 237 0.039
positive regulation of dna metabolic process GO:0051054 1 0.038
spermatid development GO:0007286 2 0.038
organic substance biosynthetic process GO:1901576 289 0.038
Human
nucleoside monophosphate catabolic process GO:0009125 4 0.038
cellular component morphogenesis GO:0032989 336 0.037
negative regulation of mitosis GO:0045839 3 0.037
spindle assembly GO:0051225 2 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.035
cellular response to organic substance GO:0071310 105 0.035
spermatid differentiation GO:0048515 2 0.035
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
Human
regulation of biological quality GO:0065008 263 0.034
homeostatic process GO:0042592 142 0.034
microtubule organizing center organization GO:0031023 1 0.034
cilium assembly GO:0042384 58 0.034
cell projection organization GO:0030030 284 0.034
b cell activation GO:0042113 2 0.033
telomere maintenance GO:0000723 1 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
Human
regulation of dna recombination GO:0000018 2 0.032
regulation of protein complex assembly GO:0043254 3 0.032
cell projection assembly GO:0030031 64 0.031
negative regulation of response to stimulus GO:0048585 104 0.031
biosynthetic process GO:0009058 294 0.031
Human
macromolecule biosynthetic process GO:0009059 227 0.031
Human
locomotion GO:0040011 313 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
Human
reciprocal dna recombination GO:0035825 1 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
regulation of biosynthetic process GO:0009889 250 0.030
Human
peptidyl serine phosphorylation GO:0018105 1 0.030
embryonic organ development GO:0048568 381 0.030
regulation of nucleic acid templated transcription GO:1903506 213 0.030
Human
growth GO:0040007 174 0.030
immune system development GO:0002520 191 0.029
intracellular signal transduction GO:0035556 85 0.029
cell morphogenesis GO:0000902 289 0.028
developmental growth GO:0048589 166 0.028
cell cycle GO:0007049 93 0.028
Human Mouse
cellular biosynthetic process GO:0044249 286 0.027
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.027
response to chemical GO:0042221 320 0.027
regulation of response to stimulus GO:0048583 269 0.027
regulation of locomotion GO:0040012 55 0.027
connective tissue development GO:0061448 99 0.027
response to abiotic stimulus GO:0009628 122 0.027
single organism metabolic process GO:0044710 217 0.026
Human
dna templated transcription initiation GO:0006352 1 0.026
mitotic recombination GO:0006312 2 0.026
regulation of signaling GO:0023051 235 0.026
eye development GO:0001654 277 0.026
b cell mediated immunity GO:0019724 3 0.026
catabolic process GO:0009056 32 0.026
Human
single organism transport GO:0044765 206 0.025
cellular protein metabolic process GO:0044267 129 0.025
negative regulation of metabolic process GO:0009892 86 0.024
Human
nucleic acid metabolic process GO:0090304 244 0.024
Human
response to organic substance GO:0010033 153 0.024
protein acetylation GO:0006473 2 0.024
regulation of signal transduction GO:0009966 225 0.024
negative regulation of gene expression GO:0010629 65 0.023
Human
cellular response to stress GO:0033554 62 0.023
Human
cellular amine metabolic process GO:0044106 2 0.023
response to external stimulus GO:0009605 264 0.023
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
chromosome organization GO:0051276 31 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.022
Human
cilium morphogenesis GO:0060271 85 0.022
amine metabolic process GO:0009308 2 0.022
system process GO:0003008 185 0.022
somatic cell dna recombination GO:0016444 1 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
Human
cellular catabolic process GO:0044248 27 0.022
Human
regulation of gene silencing GO:0060968 1 0.021
protein modification process GO:0036211 100 0.021
cellular response to external stimulus GO:0071496 2 0.021
male meiosis GO:0007140 2 0.021
protein targeting to nucleus GO:0044744 3 0.021
positive regulation of biological process GO:0048518 253 0.021
aromatic compound catabolic process GO:0019439 15 0.021
Human
aromatic compound biosynthetic process GO:0019438 217 0.021
Human
regulation of localization GO:0032879 104 0.021
cell motility GO:0048870 244 0.021
tube morphogenesis GO:0035239 349 0.021
regulation of binding GO:0051098 3 0.021
cytokinesis GO:0000910 3 0.020
angiogenesis GO:0001525 158 0.020
phagocytosis GO:0006909 3 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
camera type eye development GO:0043010 222 0.020
transport GO:0006810 220 0.020
gene expression GO:0010467 252 0.019
Human
dna catabolic process GO:0006308 1 0.019
Human
regulation of cellular amine metabolic process GO:0033238 0 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
peptidyl serine modification GO:0018209 2 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
meiotic chromosome segregation GO:0045132 3 0.019
female sex differentiation GO:0046660 4 0.019
photoreceptor cell outer segment organization GO:0035845 9 0.018
regulation of primary metabolic process GO:0080090 311 0.018
Human
negative regulation of dna replication GO:0008156 2 0.018
reciprocal meiotic recombination GO:0007131 1 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of cell activation GO:0050865 1 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
Human
regulation of response to extracellular stimulus GO:0032104 1 0.017
programmed cell death GO:0012501 119 0.017
mitotic g2 dna damage checkpoint GO:0007095 3 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
Human
rna localization GO:0006403 4 0.017
chromosome organization involved in meiosis GO:0070192 1 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
cell cycle process GO:0022402 53 0.017
Human Mouse
cellular response to chemical stimulus GO:0070887 157 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
microtubule cytoskeleton organization GO:0000226 33 0.017
negative regulation of transcription dna templated GO:0045892 45 0.017
Human
production of molecular mediator of immune response GO:0002440 2 0.017
establishment of localization GO:0051234 244 0.017
small molecule metabolic process GO:0044281 77 0.017
head development GO:0060322 303 0.017
melanosome localization GO:0032400 21 0.017
mitotic cell cycle GO:0000278 64 0.016
Mouse
rna metabolic process GO:0016070 219 0.016
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
negative regulation of rna biosynthetic process GO:1902679 45 0.016
Human
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.016
regulation of cell communication GO:0010646 232 0.016
regulation of histone methylation GO:0031060 3 0.016
positive regulation of cell division GO:0051781 2 0.016
digestive system development GO:0055123 289 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
cellular protein modification process GO:0006464 100 0.015
protein import GO:0017038 3 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
negative regulation of signal transduction GO:0009968 94 0.015
regulation of protein catabolic process GO:0042176 1 0.015
positive regulation of metabolic process GO:0009893 108 0.015
cytoskeleton organization GO:0007010 96 0.015
regulation of cytokine production GO:0001817 3 0.015
regulation of dna metabolic process GO:0051052 11 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
Mouse
negative regulation of rna metabolic process GO:0051253 48 0.014
Human
mitotic dna integrity checkpoint GO:0044774 4 0.014
histone h3 k4 methylation GO:0051568 2 0.014
single organism reproductive process GO:0044702 40 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
central nervous system development GO:0007417 387 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
anatomical structure homeostasis GO:0060249 36 0.014
macromolecular complex assembly GO:0065003 35 0.014
response to drug GO:0042493 3 0.014
regulation of blood pressure GO:0008217 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
negative regulation of cellular process GO:0048523 283 0.014
Human
regulation of cell cycle GO:0051726 52 0.014
intracellular mrna localization GO:0008298 1 0.014
gastrulation GO:0007369 208 0.014
cellular response to starvation GO:0009267 1 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
positive regulation of histone modification GO:0031058 1 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
regulation of tube size GO:0035150 2 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
Human
chromosome segregation GO:0007059 12 0.013
digestive tract development GO:0048565 265 0.013
mitotic cell cycle process GO:1903047 48 0.013
Mouse
morphogenesis of an epithelium GO:0002009 333 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
Human
determination of bilateral symmetry GO:0009855 204 0.013
germ cell development GO:0007281 22 0.013
immunoglobulin production GO:0002377 1 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
developmental programmed cell death GO:0010623 4 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
positive regulation of catabolic process GO:0009896 4 0.012
protein localization to nucleus GO:0034504 3 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
cellular ketone metabolic process GO:0042180 11 0.012
oocyte maturation GO:0001556 4 0.012
ameboidal type cell migration GO:0001667 143 0.012
cellular protein catabolic process GO:0044257 4 0.012
meiosis ii GO:0007135 1 0.012
regulation of cellular component movement GO:0051270 55 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
Human
blood vessel development GO:0001568 246 0.012
multicellular organism reproduction GO:0032504 35 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
Human
maintenance of location GO:0051235 4 0.011
hemopoiesis GO:0030097 183 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
regulation of blood vessel size GO:0050880 2 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regionalization GO:0003002 274 0.011
response to uv GO:0009411 3 0.011
histone h3 k9 modification GO:0061647 5 0.011
regulation of cell cycle g2 m phase transition GO:1902749 4 0.011
immune response GO:0006955 28 0.011
gamete generation GO:0007276 33 0.011
specification of axis polarity GO:0065001 4 0.011
multi organism process GO:0051704 134 0.011
regulation of dna replication GO:0006275 3 0.011
nuclear transport GO:0051169 4 0.011
mrna export from nucleus GO:0006406 1 0.011
macromolecule modification GO:0043412 111 0.011
neurological system process GO:0050877 62 0.011
organic cyclic compound catabolic process GO:1901361 15 0.011
Human
guanosine containing compound metabolic process GO:1901068 4 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
regulation of cell aging GO:0090342 1 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
Mouse
oxoacid metabolic process GO:0043436 31 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
cellular response to radiation GO:0071478 4 0.010
chordate embryonic development GO:0043009 271 0.010
Mouse
myeloid cell development GO:0061515 32 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
neuron projection morphogenesis GO:0048812 161 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
Human
retina development in camera type eye GO:0060041 146 0.010
vasculature development GO:0001944 278 0.010

zgc:113143 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
congenital hypoplastic anemia DOID:1342 0 0.045
immune system disease DOID:2914 0 0.045
aplastic anemia DOID:12449 0 0.045
bone marrow disease DOID:4961 0 0.045
anemia DOID:2355 0 0.045
hematopoietic system disease DOID:74 0 0.045
nervous system disease DOID:863 0 0.030
central nervous system disease DOID:331 0 0.020
tauopathy DOID:680 0 0.020
neurodegenerative disease DOID:1289 0 0.020
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019