Danio rerio

0 known processes

lap3

leucine aminopeptidase 3

(Aliases: im:7150907)

lap3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 4 0.233
larval development GO:0002164 2 0.209
zymogen activation GO:0031638 3 0.173
meiotic nuclear division GO:0007126 4 0.111
coenzyme biosynthetic process GO:0009108 2 0.095
mitochondrial transport GO:0006839 2 0.088
biosynthetic process GO:0009058 294 0.068
cofactor metabolic process GO:0051186 15 0.066
gene expression GO:0010467 252 0.056
neuron differentiation GO:0030182 353 0.049
establishment of protein localization to organelle GO:0072594 4 0.047
cellular biosynthetic process GO:0044249 286 0.047
regulation of peptidase activity GO:0052547 23 0.046
positive regulation of biological process GO:0048518 253 0.046
response to stress GO:0006950 263 0.043
positive regulation of cellular process GO:0048522 201 0.043
regulation of metabolic process GO:0019222 359 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.039
cellular response to topologically incorrect protein GO:0035967 2 0.038
cell part morphogenesis GO:0032990 246 0.038
cellular component disassembly GO:0022411 1 0.037
cellular component assembly GO:0022607 170 0.037
meiotic cell cycle process GO:1903046 3 0.034
negative regulation of cellular process GO:0048523 283 0.034
multicellular organism growth GO:0035264 4 0.033
head development GO:0060322 303 0.033
developmental growth GO:0048589 166 0.033
intra s dna damage checkpoint GO:0031573 1 0.032
response to chemical GO:0042221 320 0.032
cellular component movement GO:0006928 335 0.032
locomotion GO:0040011 313 0.031
single organism metabolic process GO:0044710 217 0.031
mononuclear cell proliferation GO:0032943 1 0.031
endoplasmic reticulum unfolded protein response GO:0030968 2 0.030
response to unfolded protein GO:0006986 2 0.029
response to external stimulus GO:0009605 264 0.029
nuclear export GO:0051168 1 0.029
er nucleus signaling pathway GO:0006984 2 0.029
organelle organization GO:0006996 227 0.029
aging GO:0007568 2 0.029
organic substance biosynthetic process GO:1901576 289 0.029
small molecule metabolic process GO:0044281 77 0.029
protein import GO:0017038 3 0.029
regulation of cellular metabolic process GO:0031323 320 0.028
brain development GO:0007420 293 0.028
signal transduction GO:0007165 455 0.027
nucleic acid metabolic process GO:0090304 244 0.027
growth GO:0040007 174 0.026
central nervous system development GO:0007417 387 0.026
organic acid metabolic process GO:0006082 31 0.026
actin polymerization or depolymerization GO:0008154 2 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.025
carboxylic acid metabolic process GO:0019752 22 0.024
heterocycle metabolic process GO:0046483 290 0.024
mitochondrion morphogenesis GO:0070584 2 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.024
dna catabolic process GO:0006308 1 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
protein metabolic process GO:0019538 183 0.023
Mouse
cellular amino acid metabolic process GO:0006520 7 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
cellular ketone metabolic process GO:0042180 11 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
cell death GO:0008219 121 0.021
organic cyclic compound metabolic process GO:1901360 301 0.020
thioester metabolic process GO:0035383 1 0.020
oxoacid metabolic process GO:0043436 31 0.020
somatic muscle development GO:0007525 4 0.020
cellular protein metabolic process GO:0044267 129 0.020
leukocyte proliferation GO:0070661 1 0.020
response to biotic stimulus GO:0009607 97 0.020
response to other organism GO:0051707 97 0.019
intracellular estrogen receptor signaling pathway GO:0030520 3 0.019
regulation of dna replication GO:0006275 3 0.019
single organism organelle organization GO:1902589 199 0.019
cell migration GO:0016477 237 0.019
generation of neurons GO:0048699 385 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
response to external biotic stimulus GO:0043207 97 0.018
double strand break repair GO:0006302 3 0.018
lipid storage GO:0019915 1 0.018
regulation of cell death GO:0010941 103 0.018
cell morphogenesis GO:0000902 289 0.018
dicarboxylic acid metabolic process GO:0043648 1 0.018
membrane invagination GO:0010324 1 0.017
organic acid catabolic process GO:0016054 3 0.017
phagocytosis engulfment GO:0006911 1 0.017
negative regulation of dna metabolic process GO:0051053 4 0.017
response to organic substance GO:0010033 153 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
actin filament polymerization GO:0030041 2 0.017
regulation of cellular component organization GO:0051128 86 0.017
pyrimidine containing compound metabolic process GO:0072527 3 0.017
single organism biosynthetic process GO:0044711 71 0.017
regulation of cytokine production GO:0001817 3 0.016
secondary metabolic process GO:0019748 3 0.016
positive regulation of cell activation GO:0050867 1 0.016
maintenance of location GO:0051235 4 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
oxidoreduction coenzyme metabolic process GO:0006733 1 0.016
phagocytosis GO:0006909 3 0.016
amine metabolic process GO:0009308 2 0.016
lymphocyte proliferation GO:0046651 1 0.015
death GO:0016265 121 0.015
single organism localization GO:1902578 225 0.015
nitrogen compound metabolic process GO:0006807 319 0.015
cell growth GO:0016049 57 0.015
protein stabilization GO:0050821 2 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
localization of cell GO:0051674 244 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.015
axon development GO:0061564 166 0.015
regulation of neurogenesis GO:0050767 87 0.015
tissue remodeling GO:0048771 4 0.015
nucleotide metabolic process GO:0009117 28 0.015
regulation of cysteine type endopeptidase activity GO:2000116 21 0.015
negative regulation of cell communication GO:0010648 96 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of catalytic activity GO:0050790 55 0.014
quinone metabolic process GO:1901661 1 0.014
positive regulation of cytokine production GO:0001819 2 0.014
protein import into nucleus GO:0006606 3 0.014
cofactor biosynthetic process GO:0051188 10 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of nervous system development GO:0051960 90 0.014
establishment of localization GO:0051234 244 0.014
oxidative phosphorylation GO:0006119 1 0.014
vasculature development GO:0001944 278 0.014
determination of left right symmetry GO:0007368 179 0.014
liver development GO:0001889 96 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
regulation of endopeptidase activity GO:0052548 23 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
cellular component biogenesis GO:0044085 178 0.014
cellular response to stress GO:0033554 62 0.014
cartilage development GO:0051216 96 0.014
cellular amine metabolic process GO:0044106 2 0.014
central nervous system neuron differentiation GO:0021953 74 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.013
stem cell proliferation GO:0072089 4 0.013
regulation of developmental process GO:0050793 247 0.013
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
reproduction GO:0000003 40 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
regulation of mrna processing GO:0050684 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
determination of bilateral symmetry GO:0009855 204 0.013
gland development GO:0048732 143 0.013
cellular localization GO:0051641 97 0.012
regulation of protein polymerization GO:0032271 2 0.012
protein processing GO:0016485 12 0.012
protein secretion GO:0009306 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
phenol containing compound biosynthetic process GO:0046189 4 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
single organism transport GO:0044765 206 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
nuclear transport GO:0051169 4 0.012
proteolysis GO:0006508 38 0.012
Mouse
specification of symmetry GO:0009799 204 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
amino acid transport GO:0006865 2 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of biosynthetic process GO:0009889 250 0.011
meiosis i GO:0007127 1 0.011
multi organism process GO:0051704 134 0.011
protein modification process GO:0036211 100 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
cell cycle arrest GO:0007050 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of programmed cell death GO:0043067 101 0.011
response to endoplasmic reticulum stress GO:0034976 6 0.011
cellular protein catabolic process GO:0044257 4 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
regulation of cell activation GO:0050865 1 0.011
b cell activation GO:0042113 2 0.011
adult behavior GO:0030534 2 0.011
regulation of protein complex assembly GO:0043254 3 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
regulation of binding GO:0051098 3 0.011
regulation of wound healing GO:0061041 2 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
positive regulation of transport GO:0051050 2 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
myeloid cell differentiation GO:0030099 86 0.010
positive regulation of peptidase activity GO:0010952 10 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
ketone biosynthetic process GO:0042181 2 0.010
regulation of primary metabolic process GO:0080090 311 0.010
protein acetylation GO:0006473 2 0.010
rna metabolic process GO:0016070 219 0.010
somatic cell dna recombination GO:0016444 1 0.010
regulation of glucose transport GO:0010827 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
establishment of localization in cell GO:0051649 77 0.010
cellular response to oxygen levels GO:0071453 1 0.010
phosphorus metabolic process GO:0006793 109 0.010

lap3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.143
nervous system disease DOID:863 0 0.073
disease of metabolism DOID:0014667 0 0.051
inherited metabolic disorder DOID:655 0 0.051
mitochondrial metabolism disease DOID:700 0 0.032
neuromuscular disease DOID:440 0 0.025
charcot marie tooth disease DOID:10595 0 0.025
neuropathy DOID:870 0 0.025
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020