Danio rerio

20 known processes

mastl

microtubule associated serine/threonine kinase-like

(Aliases: GW,zgc:100990,im:7149025,GWL,MAST-L,wu:fa02a12)

mastl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.218
nucleic acid metabolic process GO:0090304 244 0.160
regulation of metabolic process GO:0019222 359 0.148
Human
organic cyclic compound metabolic process GO:1901360 301 0.146
cellular component biogenesis GO:0044085 178 0.146
positive regulation of cell cycle GO:0045787 3 0.135
regulation of cellular metabolic process GO:0031323 320 0.114
Human
modification dependent protein catabolic process GO:0019941 3 0.108
regulation of macromolecule metabolic process GO:0060255 317 0.107
regulation of nitrogen compound metabolic process GO:0051171 251 0.104
cellular nitrogen compound metabolic process GO:0034641 290 0.101
regulation of biological quality GO:0065008 263 0.097
guanosine containing compound metabolic process GO:1901068 4 0.094
negative regulation of biological process GO:0048519 304 0.093
Human
phagocytosis GO:0006909 3 0.086
cell cycle GO:0007049 93 0.086
Human
negative regulation of cellular process GO:0048523 283 0.083
Human
programmed cell death GO:0012501 119 0.082
regulation of developmental process GO:0050793 247 0.082
cellular macromolecule metabolic process GO:0044260 391 0.081
Human
microtubule organizing center organization GO:0031023 1 0.075
establishment of localization GO:0051234 244 0.073
locomotion GO:0040011 313 0.071
aging GO:0007568 2 0.071
anterior posterior pattern specification GO:0009952 152 0.070
organic cyclic compound biosynthetic process GO:1901362 223 0.070
response to stress GO:0006950 263 0.069
meiotic nuclear division GO:0007126 4 0.069
regulation of cellular biosynthetic process GO:0031326 245 0.068
cell surface receptor signaling pathway GO:0007166 325 0.064
gtp catabolic process GO:0006184 2 0.063
central nervous system development GO:0007417 387 0.063
single organism transport GO:0044765 206 0.062
stem cell proliferation GO:0072089 4 0.061
homeostatic process GO:0042592 142 0.059
regulation of cell differentiation GO:0045595 142 0.059
sensory organ morphogenesis GO:0090596 200 0.058
cellular response to chemical stimulus GO:0070887 157 0.058
death GO:0016265 121 0.058
cell migration GO:0016477 237 0.057
positive regulation of cellular process GO:0048522 201 0.055
epithelial cell differentiation GO:0030855 116 0.055
regulation of multicellular organism growth GO:0040014 4 0.054
regionalization GO:0003002 274 0.054
regulation of meiotic cell cycle GO:0051445 1 0.054
nucleobase containing compound metabolic process GO:0006139 274 0.053
cellular component assembly GO:0022607 170 0.053
cell death GO:0008219 121 0.053
cell fate commitment GO:0045165 99 0.052
multi organism process GO:0051704 134 0.051
response to chemical GO:0042221 320 0.051
regulation of rna metabolic process GO:0051252 224 0.051
positive regulation of biological process GO:0048518 253 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.047
mitotic cell cycle GO:0000278 64 0.047
Human
transport GO:0006810 220 0.044
response to external stimulus GO:0009605 264 0.044
heterocycle metabolic process GO:0046483 290 0.044
multicellular organism growth GO:0035264 4 0.043
regulation of signal transduction GO:0009966 225 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
g1 s transition of mitotic cell cycle GO:0000082 1 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.042
head development GO:0060322 303 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
cell cycle g1 s phase transition GO:0044843 1 0.041
gene expression GO:0010467 252 0.040
organic substance catabolic process GO:1901575 28 0.040
nucleobase containing compound biosynthetic process GO:0034654 205 0.040
cell part morphogenesis GO:0032990 246 0.040
regulation of signaling GO:0023051 235 0.040
positive regulation of oocyte development GO:0060282 1 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.039
hematopoietic or lymphoid organ development GO:0048534 191 0.038
heart development GO:0007507 313 0.038
signal transduction GO:0007165 455 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
embryonic organ development GO:0048568 381 0.037
developmental process involved in reproduction GO:0003006 27 0.037
regulation of biosynthetic process GO:0009889 250 0.036
regulation of binding GO:0051098 3 0.036
neuron development GO:0048666 262 0.036
negative regulation of gene expression GO:0010629 65 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
macromolecule biosynthetic process GO:0009059 227 0.035
meiosis i GO:0007127 1 0.035
larval development GO:0002164 2 0.035
brain development GO:0007420 293 0.035
apoptotic process GO:0006915 116 0.035
rna metabolic process GO:0016070 219 0.035
positive regulation of cellular catabolic process GO:0031331 3 0.035
single organism localization GO:1902578 225 0.035
reproductive process GO:0022414 40 0.034
growth GO:0040007 174 0.034
rna biosynthetic process GO:0032774 181 0.034
ras protein signal transduction GO:0007265 7 0.033
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
double strand break repair GO:0006302 3 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.033
response to organic substance GO:0010033 153 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
developmental growth GO:0048589 166 0.033
peptidyl serine phosphorylation GO:0018105 1 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
cell projection organization GO:0030030 284 0.032
regulation of gtp catabolic process GO:0033124 2 0.032
stem cell division GO:0017145 1 0.031
myeloid cell development GO:0061515 32 0.031
cell substrate adhesion GO:0031589 4 0.031
maintenance of location GO:0051235 4 0.031
digestive system development GO:0055123 289 0.030
regulation of primary metabolic process GO:0080090 311 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.030
negative regulation of cell cycle GO:0045786 14 0.030
embryonic heart tube development GO:0035050 133 0.030
cell motility GO:0048870 244 0.029
meiotic cell cycle process GO:1903046 3 0.029
sensory organ development GO:0007423 393 0.029
gtp metabolic process GO:0046039 4 0.029
regulation of rna biosynthetic process GO:2001141 213 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
regulation of rho protein signal transduction GO:0035023 2 0.028
localization of cell GO:0051674 244 0.028
regulation of cell communication GO:0010646 232 0.028
protein localization to nucleus GO:0034504 3 0.028
cell morphogenesis GO:0000902 289 0.027
catabolic process GO:0009056 32 0.027
regulation of gene expression GO:0010468 265 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
heterocycle biosynthetic process GO:0018130 215 0.026
regulation of cell cycle GO:0051726 52 0.026
Human
regulation of cellular response to growth factor stimulus GO:0090287 35 0.026
vasculature development GO:0001944 278 0.026
regulation of apoptotic process GO:0042981 98 0.026
stem cell maintenance GO:0019827 4 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
camera type eye morphogenesis GO:0048593 108 0.026
response to carbohydrate GO:0009743 3 0.025
cellular amine metabolic process GO:0044106 2 0.025
nucleic acid templated transcription GO:0097659 181 0.025
cytoskeleton dependent cytokinesis GO:0061640 3 0.025
sex determination GO:0007530 1 0.025
cellular response to oxygen levels GO:0071453 1 0.025
cellular localization GO:0051641 97 0.025
positive regulation of catabolic process GO:0009896 4 0.025
cell projection morphogenesis GO:0048858 244 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
oogenesis GO:0048477 14 0.025
convergent extension involved in gastrulation GO:0060027 71 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.024
small gtpase mediated signal transduction GO:0007264 8 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
kidney development GO:0001822 92 0.024
phagocytosis engulfment GO:0006911 1 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
primary neural tube formation GO:0014020 1 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
multicellular organismal reproductive process GO:0048609 35 0.023
embryonic skeletal system morphogenesis GO:0048704 93 0.023
regulation of gtpase activity GO:0043087 2 0.023
positive regulation of gene expression GO:0010628 71 0.023
germ cell development GO:0007281 22 0.023
cellular protein catabolic process GO:0044257 4 0.022
neuroblast proliferation GO:0007405 2 0.022
lipid storage GO:0019915 1 0.022
negative regulation of mitotic cell cycle GO:0045930 11 0.022
myeloid cell differentiation GO:0030099 86 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
reproduction GO:0000003 40 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
centrosome organization GO:0051297 1 0.021
response to uv GO:0009411 3 0.021
positive regulation of metabolic process GO:0009893 108 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
gland development GO:0048732 143 0.021
somatic muscle development GO:0007525 4 0.021
neuron differentiation GO:0030182 353 0.021
centrosome duplication GO:0051298 1 0.021
neuron projection morphogenesis GO:0048812 161 0.021
single organism organelle organization GO:1902589 199 0.021
Human
actin filament based process GO:0030029 64 0.021
autophagy GO:0006914 4 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
peptidyl serine modification GO:0018209 2 0.020
generation of neurons GO:0048699 385 0.020
regulation of protein transport GO:0051223 3 0.020
organic substance biosynthetic process GO:1901576 289 0.020
negative regulation of biosynthetic process GO:0009890 55 0.020
single organism metabolic process GO:0044710 217 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
regulation of oocyte development GO:0060281 3 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
regulation of cell death GO:0010941 103 0.019
regulation of stem cell differentiation GO:2000736 4 0.019
ameboidal type cell migration GO:0001667 143 0.019
blood vessel morphogenesis GO:0048514 216 0.018
axon development GO:0061564 166 0.018
regulation of protein binding GO:0043393 3 0.018
regulation of synapse organization GO:0050807 3 0.018
pancreas development GO:0031016 84 0.018
tube morphogenesis GO:0035239 349 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
heart morphogenesis GO:0003007 156 0.018
gamete generation GO:0007276 33 0.018
epiboly GO:0090504 41 0.018
eye morphogenesis GO:0048592 144 0.018
eye development GO:0001654 277 0.018
amine metabolic process GO:0009308 2 0.018
regulation of protein catabolic process GO:0042176 1 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
g2 dna damage checkpoint GO:0031572 3 0.017
smad protein complex assembly GO:0007183 1 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
cellular component movement GO:0006928 335 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
type b pancreatic cell development GO:0003323 4 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
gastrulation GO:0007369 208 0.016
dna metabolic process GO:0006259 27 0.016
determination of left right symmetry GO:0007368 179 0.016
forebrain development GO:0030900 96 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
membrane fusion GO:0061025 2 0.016
rna localization GO:0006403 4 0.016
establishment or maintenance of cell polarity GO:0007163 29 0.016
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.016
negative regulation of metabolic process GO:0009892 86 0.016
Human
regulation of synaptic plasticity GO:0048167 1 0.016
biosynthetic process GO:0009058 294 0.016
cellular protein metabolic process GO:0044267 129 0.016
Human
female gamete generation GO:0007292 14 0.016
determination of bilateral symmetry GO:0009855 204 0.016
meiotic cell cycle GO:0051321 5 0.016
cell proliferation GO:0008283 80 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
nuclear import GO:0051170 3 0.015
hard palate development GO:0060022 4 0.015
renal system development GO:0072001 94 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
immune system development GO:0002520 191 0.015
liver development GO:0001889 96 0.015
dorsal convergence GO:0060030 14 0.015
regulation of autophagy GO:0010506 3 0.015
system process GO:0003008 185 0.015
axonogenesis GO:0007409 152 0.015
membrane invagination GO:0010324 1 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
muscle structure development GO:0061061 196 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
cellular component morphogenesis GO:0032989 336 0.015
female meiotic division GO:0007143 2 0.015
camera type eye development GO:0043010 222 0.015
convergent extension GO:0060026 118 0.015
stem cell differentiation GO:0048863 117 0.015
urogenital system development GO:0001655 97 0.014
positive regulation of neuron apoptotic process GO:0043525 1 0.014
transcription dna templated GO:0006351 181 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
Human
blood vessel development GO:0001568 246 0.014
regulation of receptor mediated endocytosis GO:0048259 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
single organism nuclear import GO:1902593 3 0.014
regulation of ras gtpase activity GO:0032318 2 0.014
regulation of molecular function GO:0065009 70 0.014
Human
spindle assembly involved in mitosis GO:0090307 1 0.014
regulation of hydrolase activity GO:0051336 28 0.014
Human
positive regulation of gtpase activity GO:0043547 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
negative regulation of nucleic acid templated transcription GO:1903507 45 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
cellular biosynthetic process GO:0044249 286 0.014
regulation of cell development GO:0060284 100 0.014
positive regulation of apoptotic process GO:0043065 29 0.014
regulation of epithelial to mesenchymal transition GO:0010717 3 0.014
regulation of reproductive process GO:2000241 4 0.014
tissue regeneration GO:0042246 74 0.013
response to hexose GO:0009746 3 0.013
nuclear transport GO:0051169 4 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
hepaticobiliary system development GO:0061008 98 0.013
protein metabolic process GO:0019538 183 0.013
Human
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of cellular component size GO:0032535 30 0.013
regulation of cellular component organization GO:0051128 86 0.013
organelle organization GO:0006996 227 0.013
Human
multicellular organism reproduction GO:0032504 35 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
establishment of organelle localization GO:0051656 45 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.013
protein heterooligomerization GO:0051291 1 0.013
protein targeting to nucleus GO:0044744 3 0.013
mitotic cytokinesis GO:0000281 3 0.013
mitochondrion organization GO:0007005 4 0.013
mesoderm development GO:0007498 88 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
regulation of cell shape GO:0008360 1 0.013
lipid homeostasis GO:0055088 3 0.013
positive regulation of transport GO:0051050 2 0.013
protein import GO:0017038 3 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
negative regulation of catabolic process GO:0009895 3 0.012
blood circulation GO:0008015 87 0.012
mesenchyme development GO:0060485 127 0.012
erythrocyte homeostasis GO:0034101 55 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
retina development in camera type eye GO:0060041 146 0.012
rna transport GO:0050658 2 0.012
macromolecule modification GO:0043412 111 0.012
Human
aromatic compound catabolic process GO:0019439 15 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
hindbrain development GO:0030902 91 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of protein complex assembly GO:0043254 3 0.012
homeostasis of number of cells GO:0048872 62 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
macromolecular complex assembly GO:0065003 35 0.012
protein stabilization GO:0050821 2 0.012
organelle fission GO:0048285 23 0.011
Human
regulation of protein ubiquitination GO:0031396 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
single organism cell adhesion GO:0098602 29 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
medulla oblongata development GO:0021550 4 0.011
regulation of cytokine production GO:0001817 3 0.011
cellular response to organic substance GO:0071310 105 0.011
single organism cellular localization GO:1902580 46 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
response to monosaccharide GO:0034284 3 0.011
protein import into nucleus GO:0006606 3 0.011
angiogenesis GO:0001525 158 0.011
centrosome cycle GO:0007098 1 0.011
response to glucose GO:0009749 3 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
vesicle mediated transport GO:0016192 22 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
adherens junction organization GO:0034332 4 0.011
cell substrate junction assembly GO:0007044 2 0.011
response to biotic stimulus GO:0009607 97 0.010
regulation of rho gtpase activity GO:0032319 1 0.010
nuclear division GO:0000280 23 0.010
Human
cellular carbohydrate metabolic process GO:0044262 4 0.010
mitotic cell cycle process GO:1903047 48 0.010
Human
developmental maturation GO:0021700 34 0.010
multi organism cellular process GO:0044764 2 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
compound eye development GO:0048749 2 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
sulfate transport GO:0008272 2 0.010

mastl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
disease of anatomical entity DOID:7 0 0.013
Human
immune system disease DOID:2914 0 0.011
Human