Danio rerio

5 known processes

si:ch1073-210b3.1

si:ch1073-210b3.1

si:ch1073-210b3.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.141
response to mechanical stimulus GO:0009612 24 0.117
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.114
regulation of binding GO:0051098 3 0.092
nuclear import GO:0051170 3 0.086
larval development GO:0002164 2 0.078
regulation of cellular amine metabolic process GO:0033238 0 0.076
nucleocytoplasmic transport GO:0006913 4 0.067
amine metabolic process GO:0009308 2 0.063
single organism nuclear import GO:1902593 3 0.060
central nervous system development GO:0007417 387 0.057
ubiquitin dependent protein catabolic process GO:0006511 3 0.056
cellular amine metabolic process GO:0044106 2 0.055
regulation of cellular ketone metabolic process GO:0010565 7 0.055
positive regulation of catabolic process GO:0009896 4 0.051
modification dependent macromolecule catabolic process GO:0043632 3 0.051
organic acid metabolic process GO:0006082 31 0.050
head development GO:0060322 303 0.049
response to abiotic stimulus GO:0009628 122 0.047
cellular ketone metabolic process GO:0042180 11 0.047
cellular protein catabolic process GO:0044257 4 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.044
protein targeting to nucleus GO:0044744 3 0.043
modification dependent protein catabolic process GO:0019941 3 0.040
cellular macromolecule metabolic process GO:0044260 391 0.039
protein import GO:0017038 3 0.039
positive regulation of cellular component biogenesis GO:0044089 3 0.039
phagocytosis GO:0006909 3 0.037
small molecule metabolic process GO:0044281 77 0.037
positive regulation of cellular catabolic process GO:0031331 3 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
aging GO:0007568 2 0.034
tube morphogenesis GO:0035239 349 0.034
signal transduction GO:0007165 455 0.034
protein secretion GO:0009306 1 0.034
cellular amino acid metabolic process GO:0006520 7 0.033
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
morphogenesis of an epithelium GO:0002009 333 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
response to chemical GO:0042221 320 0.031
regulation of protein ubiquitination GO:0031396 3 0.031
regulation of neural precursor cell proliferation GO:2000177 3 0.030
maintenance of location GO:0051235 4 0.030
regulation of developmental process GO:0050793 247 0.030
regionalization GO:0003002 274 0.029
organic hydroxy compound transport GO:0015850 14 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
regulation of signal transduction GO:0009966 225 0.028
brain development GO:0007420 293 0.028
anterior posterior pattern specification GO:0009952 152 0.027
regulation of biological quality GO:0065008 263 0.027
positive regulation of transport GO:0051050 2 0.027
regulation of sterol transport GO:0032371 3 0.027
multicellular organism growth GO:0035264 4 0.027
skeletal system development GO:0001501 181 0.026
system process GO:0003008 185 0.026
lipid storage GO:0019915 1 0.025
stem cell maintenance GO:0019827 4 0.025
cellular response to external stimulus GO:0071496 2 0.025
chemosensory behavior GO:0007635 1 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
somite development GO:0061053 96 0.025
nuclear transport GO:0051169 4 0.025
regulation of protein transport GO:0051223 3 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
regulation of protein catabolic process GO:0042176 1 0.024
establishment of localization GO:0051234 244 0.024
regulation of cellular protein catabolic process GO:1903362 1 0.024
single organism metabolic process GO:0044710 217 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
regulation of cell activation GO:0050865 1 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
regulation of autophagy GO:0010506 3 0.023
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of synapse assembly GO:0051963 3 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
amino acid transport GO:0006865 2 0.022
single organism localization GO:1902578 225 0.022
specification of symmetry GO:0009799 204 0.022
regulation of primary metabolic process GO:0080090 311 0.022
regulation of metabolic process GO:0019222 359 0.022
digestive tract development GO:0048565 265 0.022
chordate embryonic development GO:0043009 271 0.022
camera type eye development GO:0043010 222 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of biosynthetic process GO:0009889 250 0.021
mononuclear cell proliferation GO:0032943 1 0.021
response to drug GO:0042493 3 0.021
protein localization to nucleus GO:0034504 3 0.021
female sex differentiation GO:0046660 4 0.021
meiotic nuclear division GO:0007126 4 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
connective tissue development GO:0061448 99 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
transcription dna templated GO:0006351 181 0.020
cellular component morphogenesis GO:0032989 336 0.020
regulation of protein complex assembly GO:0043254 3 0.020
gtp metabolic process GO:0046039 4 0.020
embryonic organ development GO:0048568 381 0.020
regulation of phosphate metabolic process GO:0019220 43 0.020
membrane invagination GO:0010324 1 0.020
female gonad development GO:0008585 4 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
blood circulation GO:0008015 87 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of reproductive process GO:2000241 4 0.019
intracellular signal transduction GO:0035556 85 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
actin filament polymerization GO:0030041 2 0.019
protein import into nucleus GO:0006606 3 0.019
phagocytosis engulfment GO:0006911 1 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
muscle structure development GO:0061061 196 0.019
oxoacid metabolic process GO:0043436 31 0.019
cellular response to starvation GO:0009267 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
sensory organ development GO:0007423 393 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
cellular response to nutrient levels GO:0031669 2 0.019
leukocyte proliferation GO:0070661 1 0.018
angiogenesis GO:0001525 158 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cell migration GO:0016477 237 0.018
regulation of gene expression GO:0010468 265 0.018
regulation of response to stimulus GO:0048583 269 0.018
protein polymerization GO:0051258 4 0.018
rna biosynthetic process GO:0032774 181 0.018
cartilage development GO:0051216 96 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of sodium ion transport GO:0002028 2 0.017
autophagy GO:0006914 4 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular component disassembly GO:0022411 1 0.017
rna metabolic process GO:0016070 219 0.017
cellular biosynthetic process GO:0044249 286 0.017
transmembrane transport GO:0055085 120 0.017
regulation of transcription dna templated GO:0006355 213 0.017
membrane fusion GO:0061025 2 0.017
gtp catabolic process GO:0006184 2 0.017
circulatory system process GO:0003013 87 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
cellular component movement GO:0006928 335 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
determination of bilateral symmetry GO:0009855 204 0.017
cellular protein modification process GO:0006464 100 0.016
lymphocyte proliferation GO:0046651 1 0.016
positive regulation of gtpase activity GO:0043547 1 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
small molecule catabolic process GO:0044282 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
gene expression GO:0010467 252 0.016
muscle cell development GO:0055001 115 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
negative regulation of catabolic process GO:0009895 3 0.016
meiotic cell cycle process GO:1903046 3 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of blood pressure GO:0008217 1 0.016
hemopoiesis GO:0030097 183 0.016
cell proliferation GO:0008283 80 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
immune system process GO:0002376 241 0.016
cell morphogenesis GO:0000902 289 0.016
response to glucose GO:0009749 3 0.016
stem cell proliferation GO:0072089 4 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of cell communication GO:0010646 232 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
positive regulation of cellular process GO:0048522 201 0.015
positive regulation of biological process GO:0048518 253 0.015
golgi vesicle transport GO:0048193 3 0.015
transport GO:0006810 220 0.015
regulation of tube size GO:0035150 2 0.015
regulation of mrna processing GO:0050684 3 0.015
epithelial cell differentiation GO:0030855 116 0.015
b cell activation GO:0042113 2 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
rna localization GO:0006403 4 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
developmental programmed cell death GO:0010623 4 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
regulation of cytokine production GO:0001817 3 0.015
heterocycle biosynthetic process GO:0018130 215 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
branching morphogenesis of an epithelial tube GO:0048754 15 0.014
protein homooligomerization GO:0051260 3 0.014
organelle fusion GO:0048284 3 0.014
macromolecular complex disassembly GO:0032984 1 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
cell motility GO:0048870 244 0.014
regulation of signaling GO:0023051 235 0.014
regulation of cell shape GO:0008360 1 0.014
response to monosaccharide GO:0034284 3 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
cytokinesis GO:0000910 3 0.014
organic substance biosynthetic process GO:1901576 289 0.014
hormone transport GO:0009914 2 0.014
protein complex disassembly GO:0043241 1 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
cellular component biogenesis GO:0044085 178 0.014
atp catabolic process GO:0006200 4 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
digestive system development GO:0055123 289 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
interspecies interaction between organisms GO:0044419 4 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
nuclear export GO:0051168 1 0.013
endosome organization GO:0007032 2 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
ear development GO:0043583 127 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
lipid catabolic process GO:0016042 4 0.013
convergent extension GO:0060026 118 0.013
mitochondrion organization GO:0007005 4 0.013
positive regulation of cell activation GO:0050867 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
tissue remodeling GO:0048771 4 0.013
determination of left right symmetry GO:0007368 179 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
regulation of organelle assembly GO:1902115 4 0.013
heterocycle metabolic process GO:0046483 290 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
sequestering of metal ion GO:0051238 3 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cell part morphogenesis GO:0032990 246 0.013
protein metabolic process GO:0019538 183 0.013
neurotransmitter transport GO:0006836 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
positive regulation of immune effector process GO:0002699 3 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
lateral inhibition GO:0046331 1 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
generation of neurons GO:0048699 385 0.012
positive regulation of signal transduction GO:0009967 56 0.012
embryonic heart tube development GO:0035050 133 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
adult behavior GO:0030534 2 0.012
localization of cell GO:0051674 244 0.012
phosphorus metabolic process GO:0006793 109 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of lipid transport GO:0032368 4 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
response to external biotic stimulus GO:0043207 97 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
regulation of rna metabolic process GO:0051252 224 0.012
muscle organ development GO:0007517 101 0.012
embryonic skeletal system development GO:0048706 97 0.012
protein acylation GO:0043543 3 0.012
regulation of transporter activity GO:0032409 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
protein stabilization GO:0050821 2 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of inflammatory response GO:0050727 2 0.012
positive regulation of metabolic process GO:0009893 108 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of protein polymerization GO:0032271 2 0.012
exocytosis GO:0006887 1 0.012
spermatid development GO:0007286 2 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
chloride transmembrane transport GO:1902476 4 0.012
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
neuron development GO:0048666 262 0.012
positive regulation of reproductive process GO:2000243 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.011
retina development in camera type eye GO:0060041 146 0.011
positive regulation of multi organism process GO:0043902 3 0.011
ovulation cycle process GO:0022602 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
muscle cell differentiation GO:0042692 139 0.011
homeostatic process GO:0042592 142 0.011
negative regulation of kinase activity GO:0033673 4 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of catalytic activity GO:0050790 55 0.011
eye development GO:0001654 277 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
hormone secretion GO:0046879 2 0.011
cellular component assembly GO:0022607 170 0.011
b cell mediated immunity GO:0019724 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
cell projection organization GO:0030030 284 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
cell proliferation in hindbrain GO:0021534 4 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
glial cell migration GO:0008347 3 0.011
response to carbohydrate GO:0009743 3 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of cell projection assembly GO:0060491 4 0.011
carbohydrate homeostasis GO:0033500 1 0.011
response to organic substance GO:0010033 153 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
vasculature development GO:0001944 278 0.011
inner ear development GO:0048839 126 0.011
biosynthetic process GO:0009058 294 0.011
protein acetylation GO:0006473 2 0.011
negative regulation of biological process GO:0048519 304 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
developmental growth GO:0048589 166 0.011
spermatid differentiation GO:0048515 2 0.011
striated muscle cell development GO:0055002 108 0.011
insulin like growth factor receptor signaling pathway GO:0048009 4 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
protein dephosphorylation GO:0006470 3 0.011
olfactory lobe development GO:0021988 4 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of chromatin modification GO:1903310 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
neurotransmitter secretion GO:0007269 2 0.010
somitogenesis GO:0001756 87 0.010
meiotic chromosome segregation GO:0045132 3 0.010
regulation of cell differentiation GO:0045595 142 0.010
negative regulation of defense response GO:0031348 2 0.010
response to antibiotic GO:0046677 1 0.010
growth GO:0040007 174 0.010
blood vessel morphogenesis GO:0048514 216 0.010
somatic muscle development GO:0007525 4 0.010
nucleic acid metabolic process GO:0090304 244 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
digestive tract morphogenesis GO:0048546 231 0.010
fatty acid transport GO:0015908 1 0.010
skeletal system morphogenesis GO:0048705 102 0.010
adherens junction organization GO:0034332 4 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
urogenital system development GO:0001655 97 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
response to hexose GO:0009746 3 0.010
peptide transport GO:0015833 1 0.010
response to corticosteroid GO:0031960 1 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
positive regulation of histone modification GO:0031058 1 0.010
apoptotic process involved in development GO:1902742 2 0.010
positive regulation of cell division GO:0051781 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
centrosome organization GO:0051297 1 0.010
response to other organism GO:0051707 97 0.010
lamellipodium assembly GO:0030032 1 0.010
lamellipodium organization GO:0097581 1 0.010

si:ch1073-210b3.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011
organ system cancer DOID:0050686 0 0.010
bone disease DOID:0080001 0 0.010
connective tissue disease DOID:65 0 0.010