Danio rerio

41 known processes

ofd1

oral-facial-digital syndrome 1

(Aliases: wu:fd17e11,wu:fa07a10,zgc:92562,MGC92562)

ofd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium organization GO:0044782 71 0.398
Mouse
cell morphogenesis GO:0000902 289 0.182
Mouse
cell part morphogenesis GO:0032990 246 0.166
Mouse
cilium morphogenesis GO:0060271 85 0.150
Mouse
cilium assembly GO:0042384 58 0.140
Mouse
cell projection morphogenesis GO:0048858 244 0.123
Mouse
regulation of cell communication GO:0010646 232 0.121
Mouse
single organism localization GO:1902578 225 0.113
protein metabolic process GO:0019538 183 0.111
photoreceptor cell outer segment organization GO:0035845 9 0.110
ribonucleoside monophosphate catabolic process GO:0009158 4 0.109
cell projection organization GO:0030030 284 0.104
Mouse
sensory organ development GO:0007423 393 0.102
regulation of response to stimulus GO:0048583 269 0.093
Mouse
cellular localization GO:0051641 97 0.091
establishment of localization GO:0051234 244 0.088
modification dependent protein catabolic process GO:0019941 3 0.088
regulation of primary metabolic process GO:0080090 311 0.084
determination of left right symmetry GO:0007368 179 0.084
cellular component morphogenesis GO:0032989 336 0.082
Mouse
negative regulation of biological process GO:0048519 304 0.081
Mouse
nucleocytoplasmic transport GO:0006913 4 0.081
atp catabolic process GO:0006200 4 0.081
cell projection assembly GO:0030031 64 0.078
Mouse
signal transduction GO:0007165 455 0.078
Mouse
specification of symmetry GO:0009799 204 0.076
microtubule based movement GO:0007018 33 0.075
protein modification process GO:0036211 100 0.073
convergent extension involved in gastrulation GO:0060027 71 0.071
morphogenesis of an epithelium GO:0002009 333 0.067
positive regulation of dna metabolic process GO:0051054 1 0.067
cellular component movement GO:0006928 335 0.062
digestive tract development GO:0048565 265 0.060
digestive system development GO:0055123 289 0.059
larval development GO:0002164 2 0.059
transport GO:0006810 220 0.058
positive regulation of cellular component biogenesis GO:0044089 3 0.057
head development GO:0060322 303 0.054
intracellular signal transduction GO:0035556 85 0.054
cytokinesis GO:0000910 3 0.052
embryonic organ development GO:0048568 381 0.050
neuron development GO:0048666 262 0.050
heterocycle metabolic process GO:0046483 290 0.049
single organism organelle organization GO:1902589 199 0.048
Mouse
negative regulation of cellular process GO:0048523 283 0.048
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.046
immune system process GO:0002376 241 0.045
telomere organization GO:0032200 1 0.044
phosphorus metabolic process GO:0006793 109 0.044
maintenance of location GO:0051235 4 0.044
nucleoside monophosphate catabolic process GO:0009125 4 0.042
positive regulation of catabolic process GO:0009896 4 0.042
digestive tract morphogenesis GO:0048546 231 0.041
cellular component assembly involved in morphogenesis GO:0010927 107 0.041
Mouse
single organism transport GO:0044765 206 0.041
protein localization to nucleus GO:0034504 3 0.041
convergent extension GO:0060026 118 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
heart development GO:0007507 313 0.039
organic cyclic compound metabolic process GO:1901360 301 0.039
retina development in camera type eye GO:0060041 146 0.038
protein import into nucleus GO:0006606 3 0.038
determination of bilateral symmetry GO:0009855 204 0.038
regulation of signaling GO:0023051 235 0.038
Mouse
pigmentation GO:0043473 85 0.038
cellular response to dna damage stimulus GO:0006974 24 0.038
eye development GO:0001654 277 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
regulation of metabolic process GO:0019222 359 0.034
cellular response to organic substance GO:0071310 105 0.033
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.033
regulation of synapse organization GO:0050807 3 0.033
multicellular organism growth GO:0035264 4 0.032
protein complex subunit organization GO:0071822 46 0.032
cellular response to chemical stimulus GO:0070887 157 0.031
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.031
telomere maintenance GO:0000723 1 0.031
meiotic nuclear division GO:0007126 4 0.031
cognition GO:0050890 1 0.030
negative regulation of signaling GO:0023057 96 0.030
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
regionalization GO:0003002 274 0.029
Mouse
cellular protein modification process GO:0006464 100 0.028
positive regulation of map kinase activity GO:0043406 3 0.028
regulation of dna replication GO:0006275 3 0.027
cellular protein metabolic process GO:0044267 129 0.027
regulation of organelle assembly GO:1902115 4 0.027
purine nucleoside monophosphate catabolic process GO:0009128 4 0.027
neuron differentiation GO:0030182 353 0.027
camera type eye development GO:0043010 222 0.027
multi organism process GO:0051704 134 0.027
intracellular transport GO:0046907 32 0.027
tube morphogenesis GO:0035239 349 0.026
lipid storage GO:0019915 1 0.026
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.026
negative regulation of cell communication GO:0010648 96 0.026
Mouse
single organism metabolic process GO:0044710 217 0.026
regulation of protein ubiquitination GO:0031396 3 0.026
cellular protein catabolic process GO:0044257 4 0.026
negative regulation of response to stimulus GO:0048585 104 0.025
Mouse
negative regulation of intracellular transport GO:0032387 3 0.025
positive regulation of transport GO:0051050 2 0.025
epithelial cell differentiation GO:0030855 116 0.025
organelle localization GO:0051640 49 0.025
regulation of response to oxidative stress GO:1902882 2 0.024
regulation of protein binding GO:0043393 3 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
dna metabolic process GO:0006259 27 0.024
positive regulation of signaling GO:0023056 56 0.024
negative regulation of signal transduction GO:0009968 94 0.024
Mouse
regulation of developmental process GO:0050793 247 0.023
Mouse
negative regulation of ras protein signal transduction GO:0046580 1 0.023
positive regulation of notch signaling pathway GO:0045747 3 0.023
nuclear export GO:0051168 1 0.023
regulation of cellular component organization GO:0051128 86 0.023
establishment of localization in cell GO:0051649 77 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of skeletal muscle tissue development GO:0048641 4 0.022
negative regulation of cytoplasmic transport GO:1903650 2 0.022
regulation of binding GO:0051098 3 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
response to stress GO:0006950 263 0.022
aging GO:0007568 2 0.022
cilium movement GO:0003341 26 0.021
regulation of biological quality GO:0065008 263 0.021
microtubule based process GO:0007017 60 0.021
nuclear transport GO:0051169 4 0.021
spermatid differentiation GO:0048515 2 0.021
protein import GO:0017038 3 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
macromolecule localization GO:0033036 54 0.021
homeostatic process GO:0042592 142 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
Mouse
ear development GO:0043583 127 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.020
response to uv GO:0009411 3 0.020
organelle organization GO:0006996 227 0.020
Mouse
regulation of protein catabolic process GO:0042176 1 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
small molecule metabolic process GO:0044281 77 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
cellular response to stress GO:0033554 62 0.020
transcription dna templated GO:0006351 181 0.020
positive regulation of cell cycle GO:0045787 3 0.020
response to chemical GO:0042221 320 0.020
Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
protein complex disassembly GO:0043241 1 0.019
regulation of protein complex assembly GO:0043254 3 0.019
cellular amine metabolic process GO:0044106 2 0.019
macromolecule modification GO:0043412 111 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.018
regulation of signal transduction GO:0009966 225 0.018
Mouse
positive regulation of biological process GO:0048518 253 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
single organism nuclear import GO:1902593 3 0.018
negative regulation of protein import into nucleus GO:0042308 2 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
cellular component assembly GO:0022607 170 0.017
Mouse
renal system development GO:0072001 94 0.017
central nervous system development GO:0007417 387 0.017
nuclear import GO:0051170 3 0.017
single organism intracellular transport GO:1902582 25 0.017
phosphorylation GO:0016310 69 0.017
mitotic cell cycle GO:0000278 64 0.017
negative regulation of intracellular protein transport GO:0090317 3 0.017
double strand break repair GO:0006302 3 0.017
organic substance catabolic process GO:1901575 28 0.017
regulation of organ growth GO:0046620 3 0.017
chromosome organization GO:0051276 31 0.017
exocytosis GO:0006887 1 0.017
spermatid development GO:0007286 2 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of synapse assembly GO:0051963 3 0.017
macromolecular complex disassembly GO:0032984 1 0.016
system process GO:0003008 185 0.016
response to carbohydrate GO:0009743 3 0.016
protein dephosphorylation GO:0006470 3 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
purine nucleotide metabolic process GO:0006163 27 0.016
cell motility GO:0048870 244 0.016
regulation of gene expression GO:0010468 265 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
negative regulation of protein transport GO:0051224 3 0.016
somatic stem cell maintenance GO:0035019 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
single organism cellular localization GO:1902580 46 0.016
regulation of protein metabolic process GO:0051246 56 0.016
meiotic cell cycle process GO:1903046 3 0.016
circulatory system process GO:0003013 87 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
regulation of exocytosis GO:0017157 1 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
phosphatidylinositol mediated signaling GO:0048015 2 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
amine metabolic process GO:0009308 2 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
Mouse
fin regeneration GO:0031101 51 0.015
cytoskeleton organization GO:0007010 96 0.014
Mouse
cellular protein complex assembly GO:0043623 19 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of dna metabolic process GO:0051052 11 0.014
nonmotile primary cilium assembly GO:0035058 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
anatomical structure homeostasis GO:0060249 36 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
regulation of organelle organization GO:0033043 29 0.014
positive regulation of metabolic process GO:0009893 108 0.014
cellular catabolic process GO:0044248 27 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cartilage development GO:0051216 96 0.014
chemical homeostasis GO:0048878 49 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
catabolic process GO:0009056 32 0.014
gastrulation GO:0007369 208 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
positive regulation of cellular process GO:0048522 201 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
forebrain development GO:0030900 96 0.013
regulation of cell development GO:0060284 100 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
proteolysis GO:0006508 38 0.013
response to corticosteroid GO:0031960 1 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
microtubule bundle formation GO:0001578 9 0.013
Mouse
establishment of organelle localization GO:0051656 45 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
organic acid metabolic process GO:0006082 31 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of rho protein signal transduction GO:0035023 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular ketone metabolic process GO:0042180 11 0.012
biosynthetic process GO:0009058 294 0.012
adult behavior GO:0030534 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
negative chemotaxis GO:0050919 1 0.012
cellular component biogenesis GO:0044085 178 0.012
Mouse
chemotaxis GO:0006935 104 0.012
regulation of tube size GO:0035150 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
limbic system development GO:0021761 16 0.012
protein targeting to nucleus GO:0044744 3 0.012
developmental programmed cell death GO:0010623 4 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
protein modification by small protein conjugation or removal GO:0070647 14 0.011
protein localization GO:0008104 40 0.011
cell migration GO:0016477 237 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
oxoacid metabolic process GO:0043436 31 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
multicellular organismal response to stress GO:0033555 2 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
generation of neurons GO:0048699 385 0.011
meiosis i GO:0007127 1 0.011
regulation of glucose import GO:0046324 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
positive regulation of signal transduction GO:0009967 56 0.011
centrosome organization GO:0051297 1 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
Mouse
neuron projection development GO:0031175 180 0.010
meiotic chromosome segregation GO:0045132 3 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
hemopoiesis GO:0030097 183 0.010
wnt signaling pathway GO:0016055 80 0.010
regulation of catalytic activity GO:0050790 55 0.010
regulation of proteolysis GO:0030162 24 0.010
positive regulation of cell communication GO:0010647 56 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
negative regulation of cytokine production GO:0001818 1 0.010
negative regulation of reproductive process GO:2000242 3 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010

ofd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011