Danio rerio

17 known processes

eif2ak2

eukaryotic translation initiation factor 2-alpha kinase 2

(Aliases: pkr)

eif2ak2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene expression GO:0010467 252 0.070
Human Mouse
aging GO:0007568 2 0.065
zymogen activation GO:0031638 3 0.062
positive regulation of stress activated mapk cascade GO:0032874 3 0.061
Mouse
female sex differentiation GO:0046660 4 0.058
establishment of protein localization to organelle GO:0072594 4 0.054
larval development GO:0002164 2 0.053
immune system process GO:0002376 241 0.053
Mouse
regulation of stem cell proliferation GO:0072091 2 0.050
Mouse
regulation of reproductive process GO:2000241 4 0.050
meiotic nuclear division GO:0007126 4 0.050
immunoglobulin mediated immune response GO:0016064 3 0.049
plasminogen activation GO:0031639 3 0.045
positive regulation of transport GO:0051050 2 0.044
nitrogen compound metabolic process GO:0006807 319 0.044
Human
female gonad development GO:0008585 4 0.043
muscle cell development GO:0055001 115 0.043
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.042
Human Mouse
signal transduction GO:0007165 455 0.042
Human Mouse
interspecies interaction between organisms GO:0044419 4 0.041
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.041
Human
negative regulation of biological process GO:0048519 304 0.041
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.039
Human
embryonic organ development GO:0048568 381 0.039
cellular macromolecule metabolic process GO:0044260 391 0.039
regulation of cellular metabolic process GO:0031323 320 0.039
Human Mouse
nik nf kappab signaling GO:0038061 1 0.039
Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.039
Mouse
stem cell proliferation GO:0072089 4 0.039
Mouse
regulation of cytokine production GO:0001817 3 0.038
Mouse
positive regulation of cytokine production GO:0001819 2 0.037
Mouse
regulation of signaling GO:0023051 235 0.037
Human Mouse
protein import GO:0017038 3 0.036
protein localization to nucleus GO:0034504 3 0.036
regulation of cell communication GO:0010646 232 0.036
Human Mouse
determination of left right symmetry GO:0007368 179 0.035
sensory organ development GO:0007423 393 0.035
regulation of stem cell differentiation GO:2000736 4 0.035
Mouse
regulation of establishment of protein localization GO:0070201 4 0.035
determination of bilateral symmetry GO:0009855 204 0.034
negative regulation of cellular process GO:0048523 283 0.034
Human Mouse
regulation of protein transport GO:0051223 3 0.034
cellular biosynthetic process GO:0044249 286 0.034
Human Mouse
regulation of hormone secretion GO:0046883 2 0.034
protein metabolic process GO:0019538 183 0.034
single organism nuclear import GO:1902593 3 0.033
cell substrate adhesion GO:0031589 4 0.033
regulation of innate immune response GO:0045088 11 0.033
regulation of meiotic cell cycle GO:0051445 1 0.033
regulation of cell substrate adhesion GO:0010810 1 0.033
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.033
i kappab kinase nf kappab signaling GO:0007249 4 0.033
positive regulation of cell cycle GO:0045787 3 0.032
protein import into nucleus GO:0006606 3 0.031
androgen metabolic process GO:0008209 2 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
Human
response to topologically incorrect protein GO:0035966 2 0.031
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.031
organic substance biosynthetic process GO:1901576 289 0.031
Human Mouse
cellular response to topologically incorrect protein GO:0035967 2 0.030
Mouse
nuclear transport GO:0051169 4 0.030
development of primary female sexual characteristics GO:0046545 4 0.030
regulation of biological quality GO:0065008 263 0.030
organic cyclic compound metabolic process GO:1901360 301 0.029
Human
response to drug GO:0042493 3 0.029
response to other organism GO:0051707 97 0.029
Human
organism emergence from protective structure GO:0071684 4 0.029
response to external stimulus GO:0009605 264 0.028
Human
regulation of cytoplasmic transport GO:1903649 4 0.028
pericardium development GO:0060039 1 0.028
cellular response to unfolded protein GO:0034620 2 0.028
Mouse
interaction with host GO:0051701 4 0.028
nuclear import GO:0051170 3 0.028
regulation of primary metabolic process GO:0080090 311 0.028
Human
regulation of signal transduction GO:0009966 225 0.028
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.028
Human
chordate embryonic development GO:0043009 271 0.027
meiotic cell cycle process GO:1903046 3 0.027
positive regulation of leukocyte mediated immunity GO:0002705 1 0.027
multi organism cellular process GO:0044764 2 0.027
Human Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
immune system development GO:0002520 191 0.027
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.027
Human
nitric oxide biosynthetic process GO:0006809 2 0.027
muscle structure development GO:0061061 196 0.027
multicellular organismal response to stress GO:0033555 2 0.027
regulation of natural killer cell mediated cytotoxicity GO:0042269 1 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.026
positive regulation of secretion by cell GO:1903532 1 0.026
positive regulation of catabolic process GO:0009896 4 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
regulation of protein targeting GO:1903533 2 0.025
defense response GO:0006952 47 0.025
hematopoietic stem cell differentiation GO:0060218 20 0.025
Mouse
protein targeting to nucleus GO:0044744 3 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
peptide metabolic process GO:0006518 1 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
Human
organonitrogen compound metabolic process GO:1901564 74 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
Human
nucleic acid metabolic process GO:0090304 244 0.025
Human
cellular response to external stimulus GO:0071496 2 0.025
regulation of protein import into nucleus GO:0042306 2 0.024
regulation of metabolic process GO:0019222 359 0.024
Human Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.024
pericardium morphogenesis GO:0003344 1 0.024
establishment of localization GO:0051234 244 0.024
protein maturation GO:0051604 12 0.024
positive regulation of cell division GO:0051781 2 0.024
regulation of natural killer cell mediated immunity GO:0002715 1 0.023
positive regulation of biological process GO:0048518 253 0.023
Human Mouse
protein secretion GO:0009306 1 0.023
hormone secretion GO:0046879 2 0.023
regulation of binding GO:0051098 3 0.023
membrane lipid biosynthetic process GO:0046467 2 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
specification of symmetry GO:0009799 204 0.023
inner ear development GO:0048839 126 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
innate immune response GO:0045087 13 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
regulation of production of molecular mediator of immune response GO:0002700 1 0.022
embryonic skeletal system development GO:0048706 97 0.022
somatic muscle development GO:0007525 4 0.022
b cell activation GO:0042113 2 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.022
Human
regulation of intracellular protein transport GO:0033157 3 0.022
hormone transport GO:0009914 2 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
Human
regulation of response to stimulus GO:0048583 269 0.022
Human Mouse
autophagy GO:0006914 4 0.021
stem cell maintenance GO:0019827 4 0.021
cellular protein catabolic process GO:0044257 4 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
cell motility GO:0048870 244 0.021
response to external biotic stimulus GO:0043207 97 0.021
Human
rna biosynthetic process GO:0032774 181 0.021
Human
response to biotic stimulus GO:0009607 97 0.021
Human
response to carbohydrate GO:0009743 3 0.020
synaptic target recognition GO:0008039 1 0.020
positive regulation of secretion GO:0051047 1 0.020
cellular response to starvation GO:0009267 1 0.020
positive regulation of gtp catabolic process GO:0033126 1 0.020
cell proliferation GO:0008283 80 0.020
Human Mouse
gtp metabolic process GO:0046039 4 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
Mouse
biosynthetic process GO:0009058 294 0.020
Human Mouse
regulation of cell shape GO:0008360 1 0.020
rna localization GO:0006403 4 0.020
sphingolipid biosynthetic process GO:0030148 2 0.020
er nucleus signaling pathway GO:0006984 2 0.020
Mouse
heterocycle metabolic process GO:0046483 290 0.020
Human
positive regulation of cell adhesion GO:0045785 1 0.020
striated muscle cell differentiation GO:0051146 129 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
response to alkaloid GO:0043279 2 0.020
phagocytosis GO:0006909 3 0.020
positive regulation of cell activation GO:0050867 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
striated muscle cell development GO:0055002 108 0.019
striated muscle tissue development GO:0014706 110 0.019
hormone biosynthetic process GO:0042446 3 0.019
maintenance of location GO:0051235 4 0.019
endoplasmic reticulum unfolded protein response GO:0030968 2 0.019
Mouse
carbon dioxide transport GO:0015670 3 0.019
single organism metabolic process GO:0044710 217 0.019
Human Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.019
positive regulation of cell substrate adhesion GO:0010811 1 0.019
regulation of muscle contraction GO:0006937 3 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.019
response to chemical GO:0042221 320 0.019
Human Mouse
skeletal system development GO:0001501 181 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.018
negative regulation of reproductive process GO:2000242 3 0.018
carbohydrate homeostasis GO:0033500 1 0.018
regulation of skeletal muscle tissue development GO:0048641 4 0.018
regulation of protein catabolic process GO:0042176 1 0.018
complement activation GO:0006956 3 0.018
lipid storage GO:0019915 1 0.018
regulation of dna recombination GO:0000018 2 0.018
viral process GO:0016032 1 0.018
Human Mouse
meiosis i GO:0007127 1 0.018
cellular amide metabolic process GO:0043603 4 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
Human Mouse
cellular amine metabolic process GO:0044106 2 0.018
stem cell division GO:0017145 1 0.017
gastrulation GO:0007369 208 0.017
negative regulation of cytokine production GO:0001818 1 0.017
response to unfolded protein GO:0006986 2 0.017
Mouse
homeostatic process GO:0042592 142 0.017
amine metabolic process GO:0009308 2 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
Human
circadian sleep wake cycle GO:0042745 2 0.017
regulation of endocrine process GO:0044060 2 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
translational initiation GO:0006413 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
peptidyl serine modification GO:0018209 2 0.017
membrane invagination GO:0010324 1 0.016
fatty acid transport GO:0015908 1 0.016
cellular component movement GO:0006928 335 0.016
cell killing GO:0001906 2 0.016
response to corticosteroid GO:0031960 1 0.016
single organism localization GO:1902578 225 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
brain development GO:0007420 293 0.016
regulation of transporter activity GO:0032409 2 0.016
transport GO:0006810 220 0.016
long chain fatty acid transport GO:0015909 1 0.016
energy reserve metabolic process GO:0006112 2 0.016
leukocyte proliferation GO:0070661 1 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.016
Human Mouse
organelle organization GO:0006996 227 0.016
regulation of metal ion transport GO:0010959 4 0.016
nitric oxide metabolic process GO:0046209 2 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
cellular protein metabolic process GO:0044267 129 0.016
somitogenesis GO:0001756 87 0.016
centrosome organization GO:0051297 1 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
Human
lateral line system development GO:0048925 76 0.016
regulation of gene expression GO:0010468 265 0.016
Human
regulation of rna biosynthetic process GO:2001141 213 0.016
Human
cellular response to extracellular stimulus GO:0031668 2 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.015
Mouse
b cell mediated immunity GO:0019724 3 0.015
response to stress GO:0006950 263 0.015
Mouse
calcium ion import GO:0070509 4 0.015
skeletal system morphogenesis GO:0048705 102 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
Human
positive regulation of dna metabolic process GO:0051054 1 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of cell activation GO:0050865 1 0.015
hatching GO:0035188 4 0.015
vasculature development GO:0001944 278 0.015
post embryonic organ development GO:0048569 4 0.015
golgi vesicle transport GO:0048193 3 0.015
negative regulation of translation GO:0017148 1 0.015
Human
mechanosensory lateral line system development GO:0048881 49 0.015
protein acetylation GO:0006473 2 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
gas transport GO:0015669 3 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
fin development GO:0033333 77 0.015
anion transport GO:0006820 38 0.015
regulation of cardiac muscle contraction GO:0055117 2 0.015
nucleic acid templated transcription GO:0097659 181 0.015
Human
response to glucose GO:0009749 3 0.015
mononuclear cell proliferation GO:0032943 1 0.015
regulation of protein complex assembly GO:0043254 3 0.015
Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
positive regulation of reproductive process GO:2000243 2 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
positive regulation of immune effector process GO:0002699 3 0.015
ovulation cycle process GO:0022602 2 0.015
adherens junction organization GO:0034332 4 0.015
cell proliferation involved in heart morphogenesis GO:0061323 2 0.015
phagocytosis engulfment GO:0006911 1 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
hemopoiesis GO:0030097 183 0.015
Mouse
macroautophagy GO:0016236 1 0.014
one carbon compound transport GO:0019755 14 0.014
nucleic acid transport GO:0050657 2 0.014
morphogenesis of an epithelial fold GO:0060571 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
circadian sleep wake cycle sleep GO:0050802 1 0.014
smooth muscle contraction GO:0006939 2 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
photoreceptor cell fate specification GO:0043704 1 0.014
rna metabolic process GO:0016070 219 0.014
Human
regulation of epithelial cell proliferation GO:0050678 3 0.014
protein complex localization GO:0031503 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.014
lymphocyte proliferation GO:0046651 1 0.014
muscle tissue development GO:0060537 110 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
regulation of skeletal muscle fiber development GO:0048742 2 0.014
protein processing GO:0016485 12 0.014
regulation of tube size GO:0035150 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
macromolecular complex disassembly GO:0032984 1 0.014
single organism organelle organization GO:1902589 199 0.014
positive regulation of cell killing GO:0031343 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
somite development GO:0061053 96 0.014
transcription dna templated GO:0006351 181 0.014
Human
endocrine process GO:0050886 2 0.014
astrocyte differentiation GO:0048708 1 0.014
rna transport GO:0050658 2 0.014
regulation of wound healing GO:0061041 2 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
natural killer cell mediated immunity GO:0002228 1 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
oxidation reduction process GO:0055114 41 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
Human Mouse
protein localization to plasma membrane GO:0072659 1 0.013
multi organism process GO:0051704 134 0.013
Human Mouse
cell matrix adhesion GO:0007160 4 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
retinal rod cell development GO:0046548 4 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
Human
regulation of organelle assembly GO:1902115 4 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of transcription dna templated GO:0006355 213 0.013
Human
cellular component disassembly GO:0022411 1 0.013
appendage morphogenesis GO:0035107 56 0.013
estrogen metabolic process GO:0008210 2 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
muscle fiber development GO:0048747 52 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
muscle cell differentiation GO:0042692 139 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
membrane fusion GO:0061025 2 0.013
immunoglobulin production GO:0002377 1 0.013
stem cell differentiation GO:0048863 117 0.013
Mouse
heart process GO:0003015 71 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
localization of cell GO:0051674 244 0.013
protein complex disassembly GO:0043241 1 0.013
microtubule organizing center organization GO:0031023 1 0.013
compound eye development GO:0048749 2 0.012
actin mediated cell contraction GO:0070252 1 0.012
cellular protein modification process GO:0006464 100 0.012
establishment of localization in cell GO:0051649 77 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
establishment of endothelial barrier GO:0061028 3 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
regulation of autophagy GO:0010506 3 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
multicellular organism growth GO:0035264 4 0.012
blood vessel development GO:0001568 246 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
regulation of lymphocyte mediated immunity GO:0002706 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
Human
protein homooligomerization GO:0051260 3 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
tissue remodeling GO:0048771 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
collagen metabolic process GO:0032963 2 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
cellular component morphogenesis GO:0032989 336 0.012
neuromast development GO:0048884 46 0.012
regionalization GO:0003002 274 0.012
organelle fusion GO:0048284 3 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
Human
appendage development GO:0048736 80 0.012
cartilage development GO:0051216 96 0.012
response to glucocorticoid GO:0051384 1 0.012
protein modification process GO:0036211 100 0.012
negative regulation of multi organism process GO:0043901 3 0.012
Human Mouse
atp catabolic process GO:0006200 4 0.012
cellular response to organic substance GO:0071310 105 0.012
Mouse
cell morphogenesis GO:0000902 289 0.011
androgen biosynthetic process GO:0006702 1 0.011
sleep GO:0030431 1 0.011
regulation of developmental process GO:0050793 247 0.011
Mouse
renal tubule morphogenesis GO:0061333 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of rna metabolic process GO:0051252 224 0.011
Human
regulation of circadian rhythm GO:0042752 4 0.011
angiogenesis GO:0001525 158 0.011
ear development GO:0043583 127 0.011
cell aging GO:0007569 2 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
Human Mouse
protein polyubiquitination GO:0000209 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
muscle organ development GO:0007517 101 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
cellular component assembly GO:0022607 170 0.011
Mouse
immune effector process GO:0002252 23 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.011
regulation of translational initiation GO:0006446 1 0.011
response to bacterium GO:0009617 58 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
eye development GO:0001654 277 0.011
connective tissue development GO:0061448 99 0.011
response to nutrient GO:0007584 3 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
regulation of myotube differentiation GO:0010830 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
centrosome cycle GO:0007098 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
cell migration GO:0016477 237 0.011
calcium mediated signaling GO:0019722 2 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
regulation of immune system process GO:0002682 34 0.011
Mouse
cytoskeleton organization GO:0007010 96 0.011
cognition GO:0050890 1 0.011
negative regulation of kinase activity GO:0033673 4 0.011
fluid transport GO:0042044 17 0.011
protein dephosphorylation GO:0006470 3 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
heart contraction GO:0060047 71 0.010
positive regulation of gliogenesis GO:0014015 2 0.010
sex determination GO:0007530 1 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
oxoacid metabolic process GO:0043436 31 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
cellular component biogenesis GO:0044085 178 0.010
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
regulation of calcium ion transport GO:0051924 2 0.010
regulation of blood pressure GO:0008217 1 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
endosomal transport GO:0016197 2 0.010
positive regulation of cellular process GO:0048522 201 0.010
Human Mouse
tube morphogenesis GO:0035239 349 0.010
somatic stem cell maintenance GO:0035019 1 0.010
skeletal muscle organ development GO:0060538 78 0.010
epithelial cell differentiation GO:0030855 116 0.010
regulation of apoptotic process GO:0042981 98 0.010
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
positive regulation of innate immune response GO:0045089 8 0.010
regulation of cell killing GO:0031341 2 0.010
response to ketone GO:1901654 1 0.010
synaptic vesicle transport GO:0048489 1 0.010
alcohol biosynthetic process GO:0046165 2 0.010
locomotion GO:0040011 313 0.010
neuroblast proliferation GO:0007405 2 0.010
smooth muscle tissue development GO:0048745 1 0.010
phosphorylation GO:0016310 69 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
single organism membrane fusion GO:0044801 2 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
Human
long chain fatty acid biosynthetic process GO:0042759 1 0.010
response to hexose GO:0009746 3 0.010
regulation of molecular function GO:0065009 70 0.010
Human
peptide transport GO:0015833 1 0.010
positive regulation of neuron death GO:1901216 1 0.010

eif2ak2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
disease of cellular proliferation DOID:14566 0 0.011