Danio rerio

81 known processes

ncl1

nicalin

(Aliases: wu:fb07e09,zgc:77236,wu:fk52a06)

ncl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal process GO:0051239 277 0.457
regulation of metabolic process GO:0019222 359 0.405
multicellular organism growth GO:0035264 4 0.324
cellular protein catabolic process GO:0044257 4 0.286
regulation of multicellular organism growth GO:0040014 4 0.243
cellular macromolecule biosynthetic process GO:0034645 224 0.207
nucleic acid metabolic process GO:0090304 244 0.203
aging GO:0007568 2 0.195
organic cyclic compound metabolic process GO:1901360 301 0.185
cellular biosynthetic process GO:0044249 286 0.168
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.167
cellular macromolecule metabolic process GO:0044260 391 0.167
regulation of developmental process GO:0050793 247 0.163
determination of bilateral symmetry GO:0009855 204 0.148
regulation of biosynthetic process GO:0009889 250 0.134
regulation of macromolecule metabolic process GO:0060255 317 0.128
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.124
regulation of nucleic acid templated transcription GO:1903506 213 0.123
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.120
cellular aromatic compound metabolic process GO:0006725 295 0.119
positive regulation of biological process GO:0048518 253 0.119
cellular nitrogen compound metabolic process GO:0034641 290 0.116
specification of symmetry GO:0009799 204 0.115
gene expression GO:0010467 252 0.112
larval development GO:0002164 2 0.112
lateral inhibition GO:0046331 1 0.111
ubiquitin dependent protein catabolic process GO:0006511 3 0.106
embryonic heart tube morphogenesis GO:0003143 108 0.105
organic substance biosynthetic process GO:1901576 289 0.099
regulation of primary metabolic process GO:0080090 311 0.099
cell surface receptor signaling pathway GO:0007166 325 0.090
regulation of response to stimulus GO:0048583 269 0.090
rna biosynthetic process GO:0032774 181 0.089
cellular protein metabolic process GO:0044267 129 0.089
determination of left right symmetry GO:0007368 179 0.089
nucleic acid templated transcription GO:0097659 181 0.084
embryonic organ development GO:0048568 381 0.082
nitrogen compound metabolic process GO:0006807 319 0.082
heterocycle biosynthetic process GO:0018130 215 0.081
developmental growth GO:0048589 166 0.081
negative regulation of protein phosphorylation GO:0001933 4 0.079
positive regulation of transport GO:0051050 2 0.078
nucleobase containing compound biosynthetic process GO:0034654 205 0.077
regulation of cell communication GO:0010646 232 0.075
negative regulation of cellular process GO:0048523 283 0.075
cell death GO:0008219 121 0.071
protein metabolic process GO:0019538 183 0.070
homeostatic process GO:0042592 142 0.070
negative regulation of signal transduction GO:0009968 94 0.068
regulation of cellular metabolic process GO:0031323 320 0.067
transcription dna templated GO:0006351 181 0.065
protein modification process GO:0036211 100 0.065
rna metabolic process GO:0016070 219 0.065
heart development GO:0007507 313 0.064
mesenchyme development GO:0060485 127 0.063
cellular amine metabolic process GO:0044106 2 0.063
tube morphogenesis GO:0035239 349 0.062
establishment of protein localization to organelle GO:0072594 4 0.061
embryonic heart tube development GO:0035050 133 0.059
cellular protein modification process GO:0006464 100 0.059
ribonucleoside monophosphate catabolic process GO:0009158 4 0.059
nucleobase containing compound metabolic process GO:0006139 274 0.058
heterocycle metabolic process GO:0046483 290 0.058
apoptotic process GO:0006915 116 0.057
nucleoside monophosphate catabolic process GO:0009125 4 0.056
negative regulation of multicellular organismal process GO:0051241 69 0.055
oxoacid metabolic process GO:0043436 31 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
modification dependent macromolecule catabolic process GO:0043632 3 0.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.053
macromolecule biosynthetic process GO:0009059 227 0.053
mitochondrion organization GO:0007005 4 0.051
regionalization GO:0003002 274 0.051
regulation of gene expression GO:0010468 265 0.051
regulation of signal transduction GO:0009966 225 0.051
single organism transport GO:0044765 206 0.051
negative regulation of metabolic process GO:0009892 86 0.050
enzyme linked receptor protein signaling pathway GO:0007167 106 0.050
atp catabolic process GO:0006200 4 0.050
modification dependent protein catabolic process GO:0019941 3 0.049
macromolecule modification GO:0043412 111 0.049
pole plasm assembly GO:0007315 4 0.046
post embryonic morphogenesis GO:0009886 4 0.046
protein import GO:0017038 3 0.046
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.045
growth GO:0040007 174 0.045
maintenance of location GO:0051235 4 0.045
immune system process GO:0002376 241 0.042
negative regulation of biological process GO:0048519 304 0.042
positive regulation of cell cycle GO:0045787 3 0.042
fertilization GO:0009566 3 0.042
stem cell differentiation GO:0048863 117 0.042
compound eye development GO:0048749 2 0.041
chordate embryonic development GO:0043009 271 0.041
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
proteasomal protein catabolic process GO:0010498 2 0.040
protein secretion GO:0009306 1 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.040
brain development GO:0007420 293 0.039
regulation of biological quality GO:0065008 263 0.038
negative regulation of cellular metabolic process GO:0031324 77 0.038
response to topologically incorrect protein GO:0035966 2 0.038
heart looping GO:0001947 94 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.037
phagocytosis GO:0006909 3 0.037
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.036
immune system development GO:0002520 191 0.036
determination of heart left right asymmetry GO:0061371 117 0.036
amine metabolic process GO:0009308 2 0.036
biosynthetic process GO:0009058 294 0.035
response to chemical GO:0042221 320 0.035
somitogenesis GO:0001756 87 0.034
single organism metabolic process GO:0044710 217 0.034
epithelial tube morphogenesis GO:0060562 148 0.034
regulation of signaling GO:0023051 235 0.033
positive regulation of developmental process GO:0051094 50 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
negative regulation of gene expression GO:0010629 65 0.033
programmed cell death GO:0012501 119 0.033
anterior posterior pattern specification GO:0009952 152 0.032
establishment of localization GO:0051234 244 0.032
i kappab kinase nf kappab signaling GO:0007249 4 0.032
cellular amino acid metabolic process GO:0006520 7 0.031
cellular component movement GO:0006928 335 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.031
lipid storage GO:0019915 1 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
embryonic organ morphogenesis GO:0048562 274 0.030
regulation of developmental growth GO:0048638 38 0.030
regulation of multicellular organismal development GO:2000026 223 0.030
cellular component morphogenesis GO:0032989 336 0.030
cell motility GO:0048870 244 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.029
response to drug GO:0042493 3 0.029
negative regulation of signaling GO:0023057 96 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
cellular component disassembly GO:0022411 1 0.029
cell migration GO:0016477 237 0.028
locomotion GO:0040011 313 0.028
Worm
purine nucleoside monophosphate catabolic process GO:0009128 4 0.028
single organism localization GO:1902578 225 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
hemopoiesis GO:0030097 183 0.027
negative regulation of kinase activity GO:0033673 4 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
vasculature development GO:0001944 278 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
transport GO:0006810 220 0.026
regulation of growth GO:0040008 42 0.026
cellular response to organic substance GO:0071310 105 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.026
regulation of binding GO:0051098 3 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
head development GO:0060322 303 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.025
ion homeostasis GO:0050801 41 0.025
regulation of rna metabolic process GO:0051252 224 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
intracellular signal transduction GO:0035556 85 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
central nervous system development GO:0007417 387 0.024
defense response GO:0006952 47 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
death GO:0016265 121 0.023
post embryonic organ development GO:0048569 4 0.023
segmentation GO:0035282 97 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
protein import into nucleus GO:0006606 3 0.022
negative regulation of cell communication GO:0010648 96 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.021
mitochondrial transport GO:0006839 2 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of cellular component organization GO:0051128 86 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
response to stress GO:0006950 263 0.021
mesoderm development GO:0007498 88 0.021
system process GO:0003008 185 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
establishment of localization in cell GO:0051649 77 0.020
signal transduction GO:0007165 455 0.020
regulation of cytokine production GO:0001817 3 0.020
heart morphogenesis GO:0003007 156 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
response to external stimulus GO:0009605 264 0.020
regulation of sequestering of calcium ion GO:0051282 4 0.019
response to unfolded protein GO:0006986 2 0.019
regulation of protein binding GO:0043393 3 0.019
zymogen activation GO:0031638 3 0.019
positive regulation of rna metabolic process GO:0051254 59 0.019
cellular response to external stimulus GO:0071496 2 0.019
protein targeting to nucleus GO:0044744 3 0.019
single fertilization GO:0007338 3 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.019
single organism nuclear import GO:1902593 3 0.018
cellular ketone metabolic process GO:0042180 11 0.018
nuclear transport GO:0051169 4 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.017
organic acid metabolic process GO:0006082 31 0.017
nuclear migration GO:0007097 3 0.017
protein acetylation GO:0006473 2 0.017
cellular catabolic process GO:0044248 27 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
sensory organ development GO:0007423 393 0.017
negative regulation of blood circulation GO:1903523 2 0.017
regulation of protein targeting GO:1903533 2 0.017
protein localization to nucleus GO:0034504 3 0.017
cellular response to nutrient levels GO:0031669 2 0.017
multi organism process GO:0051704 134 0.017
nuclear import GO:0051170 3 0.017
negative regulation of cellular protein metabolic process GO:0032269 16 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
response to biotic stimulus GO:0009607 97 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
female gonad development GO:0008585 4 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
protein glycosylation GO:0006486 9 0.017
negative regulation of developmental process GO:0051093 65 0.016
circulatory system process GO:0003013 87 0.016
cellular homeostasis GO:0019725 26 0.016
cellular response to steroid hormone stimulus GO:0071383 31 0.016
defense response to other organism GO:0098542 33 0.016
cellular component assembly GO:0022607 170 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
cytoplasm organization GO:0007028 4 0.016
rna localization GO:0006403 4 0.016
transmembrane transport GO:0055085 120 0.016
localization of cell GO:0051674 244 0.016
ion transmembrane transport GO:0034220 91 0.016
negative regulation of mitosis GO:0045839 3 0.015
calcium ion homeostasis GO:0055074 19 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
response to other organism GO:0051707 97 0.015
ion transport GO:0006811 114 0.015
organelle organization GO:0006996 227 0.015
phagocytosis engulfment GO:0006911 1 0.015
diencephalon development GO:0021536 58 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
tissue remodeling GO:0048771 4 0.015
protein polyubiquitination GO:0000209 4 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
dna biosynthetic process GO:0071897 3 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
protein stabilization GO:0050821 2 0.015
regulation of protein transport GO:0051223 3 0.015
positive regulation of secretion GO:0051047 1 0.015
female sex differentiation GO:0046660 4 0.015
regulation of synapse organization GO:0050807 3 0.014
regulation of cell development GO:0060284 100 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
protein localization GO:0008104 40 0.014
cellular response to starvation GO:0009267 1 0.014
membrane invagination GO:0010324 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
cytokinesis GO:0000910 3 0.014
positive regulation of catabolic process GO:0009896 4 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
protein phosphorylation GO:0006468 47 0.014
negative regulation of autophagy GO:0010507 1 0.014
single organism organelle organization GO:1902589 199 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
calcium ion import GO:0070509 4 0.013
apoptotic process involved in morphogenesis GO:0060561 2 0.013
regulation of mesoderm development GO:2000380 11 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
eye development GO:0001654 277 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of cell activation GO:0050865 1 0.013
ovulation cycle GO:0042698 2 0.013
regulation of gtpase activity GO:0043087 2 0.013
forebrain cell migration GO:0021885 1 0.013
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.013
gtp catabolic process GO:0006184 2 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
convergent extension GO:0060026 118 0.013
striated muscle cell differentiation GO:0051146 129 0.013
ovarian follicle development GO:0001541 2 0.013
macromolecule localization GO:0033036 54 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
regulation of cell shape GO:0008360 1 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
macroautophagy GO:0016236 1 0.012
cellular amide metabolic process GO:0043603 4 0.012
protein n linked glycosylation GO:0006487 1 0.012
stem cell maintenance GO:0019827 4 0.012
blood circulation GO:0008015 87 0.012
somite development GO:0061053 96 0.012
blood vessel development GO:0001568 246 0.012
developmental programmed cell death GO:0010623 4 0.012
macromolecular complex disassembly GO:0032984 1 0.012
response to bacterium GO:0009617 58 0.012
organelle localization GO:0051640 49 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
spermatid development GO:0007286 2 0.012
dna catabolic process GO:0006308 1 0.012
stem cell development GO:0048864 82 0.012
response to organic substance GO:0010033 153 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
protein complex assembly GO:0006461 30 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
regulation of localization GO:0032879 104 0.012
regulation of reproductive process GO:2000241 4 0.012
internal protein amino acid acetylation GO:0006475 2 0.011
proteolysis GO:0006508 38 0.011
b cell activation GO:0042113 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
protein localization to plasma membrane GO:0072659 1 0.011
cellular localization GO:0051641 97 0.011
negative regulation of cell death GO:0060548 60 0.011
gtp metabolic process GO:0046039 4 0.011
stem cell proliferation GO:0072089 4 0.011
cranial nerve development GO:0021545 42 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
generation of neurons GO:0048699 385 0.011
striated muscle cell development GO:0055002 108 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
glycoprotein biosynthetic process GO:0009101 21 0.011
ribosome assembly GO:0042255 1 0.011
spindle assembly GO:0051225 2 0.011
heart contraction GO:0060047 71 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
protein acylation GO:0043543 3 0.011
regulation of transcription dna templated GO:0006355 213 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
cation homeostasis GO:0055080 33 0.011
negative regulation of catabolic process GO:0009895 3 0.011
negative regulation of reproductive process GO:2000242 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
regulation of cell death GO:0010941 103 0.011
cellular macromolecule catabolic process GO:0044265 12 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
phosphorus metabolic process GO:0006793 109 0.011
metal ion transport GO:0030001 58 0.010
regulation of metal ion transport GO:0010959 4 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
neuron apoptotic process GO:0051402 20 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
cell part morphogenesis GO:0032990 246 0.010
anatomical structure arrangement GO:0048532 2 0.010
establishment of organelle localization GO:0051656 45 0.010
spliceosomal complex assembly GO:0000245 1 0.010
olfactory lobe development GO:0021988 4 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
macromolecule catabolic process GO:0009057 15 0.010
organism emergence from protective structure GO:0071684 4 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010

ncl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
organ system cancer DOID:0050686 0 0.038
disease of metabolism DOID:0014667 0 0.026
disease of anatomical entity DOID:7 0 0.018
cardiovascular system disease DOID:1287 0 0.018
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013