Danio rerio

43 known processes

mylipa

myosin regulatory light chain interacting protein a

(Aliases: wu:fj36b03,zgc:55987,Mir,mylip)

mylipa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.129
modification dependent macromolecule catabolic process GO:0043632 3 0.121
regulation of metabolic process GO:0019222 359 0.109
cell projection morphogenesis GO:0048858 244 0.098
cellular protein catabolic process GO:0044257 4 0.098
proteasomal protein catabolic process GO:0010498 2 0.095
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.089
modification dependent protein catabolic process GO:0019941 3 0.085
ubiquitin dependent protein catabolic process GO:0006511 3 0.074
rna biosynthetic process GO:0032774 181 0.074
regulation of biosynthetic process GO:0009889 250 0.068
regulation of gene expression GO:0010468 265 0.066
larval development GO:0002164 2 0.063
regulation of multicellular organism growth GO:0040014 4 0.056
macromolecule biosynthetic process GO:0009059 227 0.052
cellular macromolecule metabolic process GO:0044260 391 0.052
Human
biosynthetic process GO:0009058 294 0.048
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.047
meiotic nuclear division GO:0007126 4 0.047
negative regulation of cellular process GO:0048523 283 0.046
locomotor rhythm GO:0045475 3 0.044
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.043
single organism organelle organization GO:1902589 199 0.042
regulation of circadian rhythm GO:0042752 4 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
cellular component morphogenesis GO:0032989 336 0.041
adult behavior GO:0030534 2 0.041
lipid storage GO:0019915 1 0.040
regulation of developmental process GO:0050793 247 0.040
multicellular organism growth GO:0035264 4 0.039
single organism metabolic process GO:0044710 217 0.038
regulation of signal transduction GO:0009966 225 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
maintenance of location GO:0051235 4 0.036
peptidyl lysine acetylation GO:0018394 2 0.036
regulation of protein catabolic process GO:0042176 1 0.035
negative regulation of biological process GO:0048519 304 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
heterocycle metabolic process GO:0046483 290 0.034
regulation of nucleic acid templated transcription GO:1903506 213 0.034
immune system development GO:0002520 191 0.033
organelle organization GO:0006996 227 0.033
meiosis i GO:0007127 1 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
cellular modified amino acid metabolic process GO:0006575 3 0.032
protein polyubiquitination GO:0000209 4 0.032
positive regulation of protein complex assembly GO:0031334 2 0.032
response to chemical GO:0042221 320 0.032
regulation of cellular metabolic process GO:0031323 320 0.031
regulation of rna metabolic process GO:0051252 224 0.030
regulation of transcription dna templated GO:0006355 213 0.030
gene expression GO:0010467 252 0.029
nucleocytoplasmic transport GO:0006913 4 0.027
organic substance biosynthetic process GO:1901576 289 0.027
system process GO:0003008 185 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
regulation of binding GO:0051098 3 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
regulation of biological quality GO:0065008 263 0.025
nucleic acid metabolic process GO:0090304 244 0.025
i kappab kinase nf kappab signaling GO:0007249 4 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
regulation of organelle assembly GO:1902115 4 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.024
negative regulation of kinase activity GO:0033673 4 0.024
developmental growth GO:0048589 166 0.024
hemopoiesis GO:0030097 183 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.023
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.022
negative regulation of cellular biosynthetic process GO:0031327 55 0.022
regulation of cell communication GO:0010646 232 0.022
meiotic chromosome segregation GO:0045132 3 0.021
membrane invagination GO:0010324 1 0.021
entrainment of circadian clock GO:0009649 2 0.021
ventricular cardiac muscle tissue development GO:0003229 3 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
negative regulation of gene expression GO:0010629 65 0.021
signal transduction GO:0007165 455 0.021
protein import GO:0017038 3 0.020
regulation of response to stimulus GO:0048583 269 0.020
b cell activation GO:0042113 2 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
regulation of mrna processing GO:0050684 3 0.020
transcription dna templated GO:0006351 181 0.020
regulation of filopodium assembly GO:0051489 2 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.018
organelle assembly GO:0070925 110 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
regulation of signaling GO:0023051 235 0.018
protein polymerization GO:0051258 4 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
protein metabolic process GO:0019538 183 0.018
Human
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
regulation of intracellular ph GO:0051453 1 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
nuclear import GO:0051170 3 0.017
regulation of sarcomere organization GO:0060297 2 0.017
meiotic cell cycle process GO:1903046 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
cell morphogenesis GO:0000902 289 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
protein dephosphorylation GO:0006470 3 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of endocrine process GO:0044060 2 0.016
nuclear transport GO:0051169 4 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
cellular protein metabolic process GO:0044267 129 0.016
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
protein modification process GO:0036211 100 0.016
Human
rna metabolic process GO:0016070 219 0.016
protein acetylation GO:0006473 2 0.016
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
macromolecule modification GO:0043412 111 0.015
Human
internal peptidyl lysine acetylation GO:0018393 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
response to stress GO:0006950 263 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
negative regulation of signal transduction GO:0009968 94 0.015
positive regulation of transport GO:0051050 2 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
small molecule catabolic process GO:0044282 3 0.015
long chain fatty acid metabolic process GO:0001676 1 0.015
cellular biosynthetic process GO:0044249 286 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
cell projection organization GO:0030030 284 0.015
male meiosis GO:0007140 2 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
response to ketone GO:1901654 1 0.014
negative regulation of metabolic process GO:0009892 86 0.014
regulation of dna templated transcription in response to stress GO:0043620 0 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
response to hypoxia GO:0001666 25 0.014
b cell differentiation GO:0030183 1 0.013
regulation of protein metabolic process GO:0051246 56 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
positive regulation of striated muscle cell differentiation GO:0051155 1 0.013
specification of symmetry GO:0009799 204 0.013
response to dexamethasone GO:0071548 1 0.013
stem cell maintenance GO:0019827 4 0.013
transport GO:0006810 220 0.013
vasculature development GO:0001944 278 0.013
regionalization GO:0003002 274 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
protein acylation GO:0043543 3 0.013
response to bacterium GO:0009617 58 0.013
entrainment of circadian clock by photoperiod GO:0043153 1 0.013
smooth muscle tissue development GO:0048745 1 0.013
regulation of organ growth GO:0046620 3 0.013
rna localization GO:0006403 4 0.013
regulation of cell activation GO:0050865 1 0.013
cell part morphogenesis GO:0032990 246 0.013
response to biotic stimulus GO:0009607 97 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
mitochondrion organization GO:0007005 4 0.013
dna metabolic process GO:0006259 27 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.012
protein localization to nucleus GO:0034504 3 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
aging GO:0007568 2 0.012
actin filament based process GO:0030029 64 0.012
regulation of lipid transport GO:0032368 4 0.012
cell proliferation involved in heart morphogenesis GO:0061323 2 0.012
iron ion homeostasis GO:0055072 4 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
steroid hormone secretion GO:0035929 1 0.012
regulation of ph GO:0006885 3 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of cellular ph GO:0030641 1 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
positive regulation of cell cycle GO:0045787 3 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
regulation of cell projection assembly GO:0060491 4 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
autophagy GO:0006914 4 0.011
positive regulation of metabolic process GO:0009893 108 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of reproductive process GO:2000241 4 0.011
phagocytosis GO:0006909 3 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
positive regulation of cellular process GO:0048522 201 0.011
negative regulation of cell death GO:0060548 60 0.011
protein stabilization GO:0050821 2 0.011
ph reduction GO:0045851 1 0.011
organic acid metabolic process GO:0006082 31 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
protein import into nucleus GO:0006606 3 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
positive regulation of biological process GO:0048518 253 0.011
immune system process GO:0002376 241 0.011
pronephros development GO:0048793 69 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
lipid metabolic process GO:0006629 52 0.010
response to nutrient GO:0007584 3 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
neuron projection morphogenesis GO:0048812 161 0.010

mylipa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.014
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
aplastic anemia DOID:12449 0 0.011
bone marrow disease DOID:4961 0 0.011
anemia DOID:2355 0 0.011