Danio rerio

35 known processes

mical2b

microtubule associated monoxygenase, calponin and LIM domain containing 2b

(Aliases: si:ch211-192p3.2)

mical2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ameboidal type cell migration GO:0001667 143 0.720
regulation of transcription dna templated GO:0006355 213 0.594
digestive tract development GO:0048565 265 0.590
cellular component movement GO:0006928 335 0.488
larval development GO:0002164 2 0.487
specification of symmetry GO:0009799 204 0.474
heart contraction GO:0060047 71 0.447
digestive system development GO:0055123 289 0.394
embryonic organ development GO:0048568 381 0.371
heart development GO:0007507 313 0.336
aging GO:0007568 2 0.330
cell motility GO:0048870 244 0.262
digestive tract morphogenesis GO:0048546 231 0.260
cilium morphogenesis GO:0060271 85 0.259
cellular component biogenesis GO:0044085 178 0.256
tube morphogenesis GO:0035239 349 0.246
immune system process GO:0002376 241 0.242
chemotaxis GO:0006935 104 0.234
regulation of cellular metabolic process GO:0031323 320 0.232
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.217
cell projection organization GO:0030030 284 0.211
cellular nitrogen compound metabolic process GO:0034641 290 0.197
epithelial tube morphogenesis GO:0060562 148 0.188
inner ear development GO:0048839 126 0.185
morphogenesis of an epithelium GO:0002009 333 0.183
heterocycle biosynthetic process GO:0018130 215 0.175
cell proliferation GO:0008283 80 0.174
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.160
regulation of biosynthetic process GO:0009889 250 0.152
regulation of cell growth GO:0001558 29 0.151
positive regulation of striated muscle tissue development GO:0045844 1 0.148
cellular response to extracellular stimulus GO:0031668 2 0.140
cardiac muscle tissue development GO:0048738 48 0.138
regulation of rna biosynthetic process GO:2001141 213 0.136
cellular component morphogenesis GO:0032989 336 0.136
organic substance biosynthetic process GO:1901576 289 0.132
striated muscle tissue development GO:0014706 110 0.131
brain development GO:0007420 293 0.131
central nervous system development GO:0007417 387 0.128
regulation of synapse assembly GO:0051963 3 0.127
signal transduction GO:0007165 455 0.124
protein localization to nucleus GO:0034504 3 0.117
determination of bilateral symmetry GO:0009855 204 0.114
nucleic acid templated transcription GO:0097659 181 0.109
muscle tissue development GO:0060537 110 0.109
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.106
regulation of synapse organization GO:0050807 3 0.101
regulation of primary metabolic process GO:0080090 311 0.100
sensory organ development GO:0007423 393 0.099
biosynthetic process GO:0009058 294 0.097
embryonic heart tube development GO:0035050 133 0.094
hematopoietic or lymphoid organ development GO:0048534 191 0.094
regulation of nucleic acid templated transcription GO:1903506 213 0.093
rna biosynthetic process GO:0032774 181 0.093
cell projection morphogenesis GO:0048858 244 0.091
cellular biosynthetic process GO:0044249 286 0.091
regulation of macromolecule biosynthetic process GO:0010556 225 0.088
lipid homeostasis GO:0055088 3 0.087
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.086
cell part morphogenesis GO:0032990 246 0.085
regulation of rna metabolic process GO:0051252 224 0.085
nuclear transport GO:0051169 4 0.084
positive regulation of cellular process GO:0048522 201 0.081
cell migration involved in gastrulation GO:0042074 79 0.081
regulation of organ growth GO:0046620 3 0.080
regulation of cell shape GO:0008360 1 0.079
eye development GO:0001654 277 0.078
cellular macromolecule metabolic process GO:0044260 391 0.076
nucleic acid metabolic process GO:0090304 244 0.072
cell matrix adhesion GO:0007160 4 0.071
organic cyclic compound biosynthetic process GO:1901362 223 0.071
protein metabolic process GO:0019538 183 0.067
forebrain development GO:0030900 96 0.066
cellular component assembly GO:0022607 170 0.066
single organism organelle organization GO:1902589 199 0.066
positive regulation of metabolic process GO:0009893 108 0.065
cellular protein complex assembly GO:0043623 19 0.064
aromatic compound biosynthetic process GO:0019438 217 0.064
synaptic growth at neuromuscular junction GO:0051124 2 0.063
mitotic cell cycle GO:0000278 64 0.063
circulatory system process GO:0003013 87 0.063
single organism transport GO:0044765 206 0.063
nucleocytoplasmic transport GO:0006913 4 0.062
stem cell development GO:0048864 82 0.061
cardiac atrium development GO:0003230 4 0.060
generation of neurons GO:0048699 385 0.058
cell morphogenesis GO:0000902 289 0.057
multi organism cellular process GO:0044764 2 0.057
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
cell adhesion GO:0007155 40 0.056
macromolecule biosynthetic process GO:0009059 227 0.056
localization of cell GO:0051674 244 0.056
positive regulation of muscle organ development GO:0048636 1 0.055
nucleobase containing compound metabolic process GO:0006139 274 0.054
cell surface receptor signaling pathway GO:0007166 325 0.054
negative regulation of tor signaling GO:0032007 2 0.053
cell substrate adhesion GO:0031589 4 0.053
positive regulation of carbohydrate metabolic process GO:0045913 1 0.052
g1 s transition of mitotic cell cycle GO:0000082 1 0.052
positive regulation of gene expression GO:0010628 71 0.052
transport GO:0006810 220 0.052
regulation of cysteine type endopeptidase activity GO:2000116 21 0.051
pyruvate metabolic process GO:0006090 1 0.051
embryonic organ morphogenesis GO:0048562 274 0.050
heart process GO:0003015 71 0.050
camera type eye development GO:0043010 222 0.049
glucose homeostasis GO:0042593 1 0.049
regulation of heart contraction GO:0008016 32 0.048
actomyosin structure organization GO:0031032 53 0.047
regulation of protein transport GO:0051223 3 0.047
response to alkaloid GO:0043279 2 0.047
transcription from rna polymerase ii promoter GO:0006366 80 0.046
cellular response to nutrient levels GO:0031669 2 0.046
enzyme linked receptor protein signaling pathway GO:0007167 106 0.046
cytoskeleton organization GO:0007010 96 0.045
single organism localization GO:1902578 225 0.045
cell migration GO:0016477 237 0.045
regulation of multicellular organismal development GO:2000026 223 0.045
locomotory behavior GO:0007626 34 0.044
chemical homeostasis GO:0048878 49 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
locomotion GO:0040011 313 0.043
stem cell differentiation GO:0048863 117 0.042
embryonic hemopoiesis GO:0035162 53 0.042
cardiac atrium morphogenesis GO:0003209 2 0.041
response to stress GO:0006950 263 0.041
cell growth GO:0016049 57 0.041
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.041
transcription dna templated GO:0006351 181 0.040
regulation of embryonic development GO:0045995 47 0.040
negative regulation of dna metabolic process GO:0051053 4 0.040
regulation of growth GO:0040008 42 0.040
regulation of cell cycle GO:0051726 52 0.039
cellular carbohydrate metabolic process GO:0044262 4 0.039
protein import into nucleus GO:0006606 3 0.038
regulation of cellular biosynthetic process GO:0031326 245 0.038
erythrocyte homeostasis GO:0034101 55 0.038
multi organism reproductive process GO:0044703 36 0.038
negative regulation of protein complex assembly GO:0031333 1 0.038
organic cyclic compound metabolic process GO:1901360 301 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
homeostatic process GO:0042592 142 0.037
establishment of localization GO:0051234 244 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.037
response to dexamethasone GO:0071548 1 0.037
blood circulation GO:0008015 87 0.037
head development GO:0060322 303 0.036
mesenchymal cell development GO:0014031 78 0.036
taxis GO:0042330 109 0.036
regulation of developmental growth GO:0048638 38 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
actin filament based process GO:0030029 64 0.035
positive regulation of cell cycle GO:0045787 3 0.035
tube closure GO:0060606 1 0.035
regulation of cell matrix adhesion GO:0001952 1 0.035
lateral line development GO:0048882 66 0.034
positive regulation of transport GO:0051050 2 0.034
epidermis development GO:0008544 48 0.034
positive regulation of biosynthetic process GO:0009891 68 0.034
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.034
otolith development GO:0048840 32 0.033
regulation of carbohydrate metabolic process GO:0006109 4 0.033
energy homeostasis GO:0097009 3 0.033
positive regulation of biological process GO:0048518 253 0.033
regulation of circadian rhythm GO:0042752 4 0.032
regulation of reproductive process GO:2000241 4 0.032
response to organic substance GO:0010033 153 0.032
nitrogen compound metabolic process GO:0006807 319 0.032
regulation of gene expression GO:0010468 265 0.031
catabolic process GO:0009056 32 0.030
gland development GO:0048732 143 0.030
regulation of cardiac muscle tissue development GO:0055024 1 0.030
ectodermal placode development GO:0071696 37 0.030
cell cycle g2 m phase transition GO:0044839 4 0.030
response to hexose GO:0009746 3 0.030
response to ketone GO:1901654 1 0.030
cell cycle process GO:0022402 53 0.029
regulation of lipid catabolic process GO:0050994 2 0.029
ras protein signal transduction GO:0007265 7 0.029
intestinal absorption GO:0050892 2 0.029
regulation of metabolic process GO:0019222 359 0.029
regulation of biological quality GO:0065008 263 0.029
regulation of ion transmembrane transporter activity GO:0032412 2 0.029
homeostasis of number of cells GO:0048872 62 0.029
vasculature development GO:0001944 278 0.029
nuclear export GO:0051168 1 0.028
actin cytoskeleton organization GO:0030036 63 0.028
biological adhesion GO:0022610 40 0.028
cell cycle g1 s phase transition GO:0044843 1 0.028
actin filament organization GO:0007015 15 0.028
small gtpase mediated signal transduction GO:0007264 8 0.028
protein depolymerization GO:0051261 1 0.028
rna metabolic process GO:0016070 219 0.027
determination of left right symmetry GO:0007368 179 0.027
autophagy GO:0006914 4 0.027
cellular response to external stimulus GO:0071496 2 0.027
multi organism process GO:0051704 134 0.027
gastrulation GO:0007369 208 0.027
negative regulation of catabolic process GO:0009895 3 0.026
developmental growth GO:0048589 166 0.026
regulation of heart growth GO:0060420 2 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
muscle structure development GO:0061061 196 0.026
sensory perception of smell GO:0007608 2 0.026
regulation of localization GO:0032879 104 0.026
determination of ventral identity GO:0048264 21 0.025
mesenchyme development GO:0060485 127 0.025
positive regulation of nervous system development GO:0051962 25 0.025
regulation of protein complex assembly GO:0043254 3 0.025
organelle assembly GO:0070925 110 0.025
system process GO:0003008 185 0.025
cellular response to hypoxia GO:0071456 1 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
muscle cell fate determination GO:0007521 1 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
gene expression GO:0010467 252 0.025
regeneration GO:0031099 91 0.025
ovarian follicle development GO:0001541 2 0.024
regulation of cellular component biogenesis GO:0044087 12 0.024
axon development GO:0061564 166 0.024
regionalization GO:0003002 274 0.023
skeletal muscle organ development GO:0060538 78 0.023
regulation of apoptotic process GO:0042981 98 0.023
cytokinesis GO:0000910 3 0.023
convergent extension involved in gastrulation GO:0060027 71 0.023
protein complex subunit organization GO:0071822 46 0.023
cell cycle GO:0007049 93 0.023
mesenchymal cell differentiation GO:0048762 87 0.022
cation transport GO:0006812 81 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
cellular response to hormone stimulus GO:0032870 39 0.022
cellular localization GO:0051641 97 0.022
response to hormone GO:0009725 48 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
rna localization GO:0006403 4 0.022
programmed cell death GO:0012501 119 0.022
neural crest cell differentiation GO:0014033 72 0.021
fin morphogenesis GO:0033334 53 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
circadian rhythm GO:0007623 19 0.021
blood vessel morphogenesis GO:0048514 216 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
mitochondrion organization GO:0007005 4 0.021
organelle organization GO:0006996 227 0.021
regulation of membrane potential GO:0042391 23 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
convergent extension GO:0060026 118 0.021
response to nutrient levels GO:0031667 10 0.020
compound eye development GO:0048749 2 0.020
post embryonic organ development GO:0048569 4 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.020
embryonic pattern specification GO:0009880 44 0.020
peptidyl serine modification GO:0018209 2 0.020
cellular protein modification process GO:0006464 100 0.020
nephron tubule morphogenesis GO:0072078 1 0.020
metal ion transport GO:0030001 58 0.020
ion transport GO:0006811 114 0.020
protein import GO:0017038 3 0.019
regulation of cellular component movement GO:0051270 55 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.019
protein targeting to nucleus GO:0044744 3 0.019
organelle localization GO:0051640 49 0.019
pectoral fin development GO:0033339 50 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
regulation of cell proliferation GO:0042127 37 0.019
skeletal muscle tissue development GO:0007519 67 0.019
neuron projection extension GO:1990138 45 0.019
carbohydrate homeostasis GO:0033500 1 0.019
multicellular organism growth GO:0035264 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
nuclear import GO:0051170 3 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.018
regulation of cell differentiation GO:0045595 142 0.018
positive regulation of cell proliferation GO:0008284 15 0.018
embryonic skeletal joint development GO:0072498 3 0.018
specification of organ identity GO:0010092 2 0.018
female gamete generation GO:0007292 14 0.018
cellular response to starvation GO:0009267 1 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
negative regulation of gene expression GO:0010629 65 0.018
hemopoiesis GO:0030097 183 0.018
positive regulation of catabolic process GO:0009896 4 0.018
single organism nuclear import GO:1902593 3 0.018
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.017
heterocycle metabolic process GO:0046483 290 0.017
blood vessel development GO:0001568 246 0.017
muscle cell differentiation GO:0042692 139 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
protein stabilization GO:0050821 2 0.017
determination of dorsal ventral asymmetry GO:0048262 34 0.017
immune system development GO:0002520 191 0.017
negative regulation of cellular process GO:0048523 283 0.017
cellular response to oxygen levels GO:0071453 1 0.017
sensory organ morphogenesis GO:0090596 200 0.017
lateral line system development GO:0048925 76 0.017
skin development GO:0043588 54 0.016
response to chemical GO:0042221 320 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
negative regulation of translation GO:0017148 1 0.016
inner ear morphogenesis GO:0042472 63 0.016
stem cell maintenance GO:0019827 4 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
morphogenesis of embryonic epithelium GO:0016331 30 0.016
embryonic pectoral fin morphogenesis GO:0035118 24 0.016
kupffer s vesicle development GO:0070121 50 0.015
endocrine system development GO:0035270 65 0.015
primary neural tube formation GO:0014020 1 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of transporter activity GO:0032409 2 0.015
negative regulation of muscle cell differentiation GO:0051148 1 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
muscle contraction GO:0006936 18 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
mechanosensory lateral line system development GO:0048881 49 0.015
single organism metabolic process GO:0044710 217 0.015
positive regulation of synapse assembly GO:0051965 1 0.015
mitotic nuclear division GO:0007067 18 0.014
viral process GO:0016032 1 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
cellular response to stress GO:0033554 62 0.014
negative regulation of blood circulation GO:1903523 2 0.014
cell substrate junction assembly GO:0007044 2 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
hepaticobiliary system development GO:0061008 98 0.014
regulation of autophagy GO:0010506 3 0.014
lipid digestion GO:0044241 3 0.014
intracellular signal transduction GO:0035556 85 0.014
response to starvation GO:0042594 5 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.014
aorta morphogenesis GO:0035909 3 0.014
striated muscle cell development GO:0055002 108 0.014
cardiac chamber development GO:0003205 19 0.014
phosphorylation GO:0016310 69 0.014
cell death GO:0008219 121 0.013
regulation of cellular component size GO:0032535 30 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
response to hydrogen peroxide GO:0042542 3 0.013
response to glucose GO:0009749 3 0.013
angiogenesis GO:0001525 158 0.013
muscle tissue morphogenesis GO:0060415 7 0.013
adult behavior GO:0030534 2 0.013
positive regulation of signal transduction GO:0009967 56 0.013
myeloid cell homeostasis GO:0002262 56 0.013
response to monosaccharide GO:0034284 3 0.013
appendage morphogenesis GO:0035107 56 0.013
cardiac muscle tissue morphogenesis GO:0055008 7 0.013
regulation of metal ion transport GO:0010959 4 0.013
axon guidance GO:0007411 86 0.013
ear development GO:0043583 127 0.013
negative regulation of ras protein signal transduction GO:0046580 1 0.013
cellular catabolic process GO:0044248 27 0.013
protein complex disassembly GO:0043241 1 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
protein complex biogenesis GO:0070271 30 0.013
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
response to endogenous stimulus GO:0009719 83 0.012
growth GO:0040007 174 0.012
neuron projection development GO:0031175 180 0.012
organic substance transport GO:0071702 58 0.012
mesoderm formation GO:0001707 43 0.012
glucose import GO:0046323 2 0.012
hydrogen peroxide metabolic process GO:0042743 2 0.012
rna modification GO:0009451 2 0.012
regulation of cell maturation GO:1903429 1 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
cation transmembrane transport GO:0098655 65 0.012
macromolecule modification GO:0043412 111 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
posterior lateral line development GO:0048916 38 0.012
response to metal ion GO:0010038 34 0.012
neuron projection guidance GO:0097485 86 0.012
smooth muscle tissue development GO:0048745 1 0.012
cation homeostasis GO:0055080 33 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
regulation of dna replication GO:0006275 3 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
eye morphogenesis GO:0048592 144 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
regulation of hydrolase activity GO:0051336 28 0.011
startle response GO:0001964 4 0.011
calcium mediated signaling GO:0019722 2 0.011
single organism cellular localization GO:1902580 46 0.011
interspecies interaction between organisms GO:0044419 4 0.011
heart morphogenesis GO:0003007 156 0.011
regulation of locomotion GO:0040012 55 0.011
establishment or maintenance of cell polarity GO:0007163 29 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of transmembrane transport GO:0034762 18 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of protein catabolic process GO:0042176 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
actin filament bundle organization GO:0061572 6 0.011
gtp catabolic process GO:0006184 2 0.011
cilium movement GO:0003341 26 0.011
membrane repolarization GO:0086009 2 0.011
wound healing GO:0042060 90 0.011
regulation of protein binding GO:0043393 3 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
response to uv GO:0009411 3 0.011
locus ceruleus development GO:0021703 3 0.011
chordate embryonic development GO:0043009 271 0.011
exocrine system development GO:0035272 28 0.011
rna 3 end processing GO:0031123 2 0.011
regulation of muscle organ development GO:0048634 9 0.011
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.010
response to corticosteroid GO:0031960 1 0.010
germ line stem cell maintenance GO:0030718 2 0.010
cell migration involved in heart development GO:0060973 22 0.010
inorganic ion transmembrane transport GO:0098660 57 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
exocrine pancreas development GO:0031017 28 0.010
neural crest cell development GO:0014032 62 0.010
bmp signaling pathway GO:0030509 52 0.010
lipid metabolic process GO:0006629 52 0.010
striated muscle cell differentiation GO:0051146 129 0.010
axon extension GO:0048675 45 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
glucocorticoid metabolic process GO:0008211 2 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
regulation of neurogenesis GO:0050767 87 0.010

mical2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.102
disease of anatomical entity DOID:7 0 0.102
hematopoietic system disease DOID:74 0 0.073
muscular disease DOID:0080000 0 0.023
musculoskeletal system disease DOID:17 0 0.023
muscle tissue disease DOID:66 0 0.023
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.013
myopathy DOID:423 0 0.010