Danio rerio

0 known processes

zgc:55936

zgc:55936

(Aliases: MGC55936,fc66f09,wu:fc66f09,zgc:77313,Rnf8)

zgc:55936 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.211
positive regulation of cellular process GO:0048522 201 0.113
Human
nucleic acid metabolic process GO:0090304 244 0.099
Human
organelle organization GO:0006996 227 0.093
Human
regulation of cell communication GO:0010646 232 0.093
nucleocytoplasmic transport GO:0006913 4 0.086
aging GO:0007568 2 0.081
rna metabolic process GO:0016070 219 0.080
Human
regulation of biosynthetic process GO:0009889 250 0.079
Human
locomotion GO:0040011 313 0.075
positive regulation of biological process GO:0048518 253 0.075
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.074
Human
heterocycle biosynthetic process GO:0018130 215 0.073
Human
response to chemical GO:0042221 320 0.073
organic cyclic compound metabolic process GO:1901360 301 0.072
Human
single organism nuclear import GO:1902593 3 0.070
cell surface receptor signaling pathway GO:0007166 325 0.070
generation of neurons GO:0048699 385 0.068
signal transduction GO:0007165 455 0.067
negative regulation of biological process GO:0048519 304 0.066
Human
regulation of establishment of protein localization GO:0070201 4 0.063
positive regulation of transport GO:0051050 2 0.063
nuclear transport GO:0051169 4 0.063
embryo development ending in birth or egg hatching GO:0009792 271 0.062
cell projection morphogenesis GO:0048858 244 0.059
apoptotic process GO:0006915 116 0.058
cell death GO:0008219 121 0.057
multicellular organism growth GO:0035264 4 0.057
cellular nitrogen compound metabolic process GO:0034641 290 0.057
Human
regionalization GO:0003002 274 0.056
regulation of multicellular organism growth GO:0040014 4 0.056
positive regulation of metabolic process GO:0009893 108 0.056
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.055
Human
cellular response to chemical stimulus GO:0070887 157 0.054
eye development GO:0001654 277 0.053
cellular component morphogenesis GO:0032989 336 0.053
cellular biosynthetic process GO:0044249 286 0.050
Human
locomotor rhythm GO:0045475 3 0.050
transcription dna templated GO:0006351 181 0.049
Human
nitrogen compound metabolic process GO:0006807 319 0.049
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
Human
regulation of smoothened signaling pathway GO:0008589 18 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.046
Human
regulation of protein transport GO:0051223 3 0.045
gene expression GO:0010467 252 0.045
Human
rna localization GO:0006403 4 0.044
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
Human
stem cell division GO:0017145 1 0.044
compound eye development GO:0048749 2 0.043
programmed cell death GO:0012501 119 0.042
regulation of transcription dna templated GO:0006355 213 0.042
Human
positive regulation of cellular metabolic process GO:0031325 94 0.041
Human
stem cell maintenance GO:0019827 4 0.041
regulation of signaling GO:0023051 235 0.040
response to abiotic stimulus GO:0009628 122 0.040
Human
heterocycle metabolic process GO:0046483 290 0.040
Human
regulation of cell death GO:0010941 103 0.040
regulation of circadian rhythm GO:0042752 4 0.039
cell part morphogenesis GO:0032990 246 0.039
protein localization to nucleus GO:0034504 3 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
Human
regulation of metabolic process GO:0019222 359 0.039
Human
wnt signaling pathway GO:0016055 80 0.038
cell aging GO:0007569 2 0.038
cell projection organization GO:0030030 284 0.038
biosynthetic process GO:0009058 294 0.037
Human
neuron differentiation GO:0030182 353 0.037
protein import GO:0017038 3 0.037
cellular macromolecule metabolic process GO:0044260 391 0.037
Human
regulation of meiotic cell cycle GO:0051445 1 0.036
cellular component biogenesis GO:0044085 178 0.036
centrosome organization GO:0051297 1 0.035
neuroblast proliferation GO:0007405 2 0.035
single organism organelle organization GO:1902589 199 0.035
Human
regulation of protein ubiquitination GO:0031396 3 0.035
erk1 and erk2 cascade GO:0070371 4 0.035
organelle fission GO:0048285 23 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
Human
regulation of gene expression GO:0010468 265 0.035
Human
nuclear import GO:0051170 3 0.034
nuclear export GO:0051168 1 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
Human
meiotic nuclear division GO:0007126 4 0.034
positive regulation of jun kinase activity GO:0043507 2 0.034
cell morphogenesis involved in differentiation GO:0000904 195 0.033
regulation of apoptotic process GO:0042981 98 0.033
cellular protein catabolic process GO:0044257 4 0.033
Human
regulation of signal transduction GO:0009966 225 0.033
cellular component movement GO:0006928 335 0.033
cellular localization GO:0051641 97 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
phagocytosis GO:0006909 3 0.032
regulation of developmental process GO:0050793 247 0.032
neuron projection development GO:0031175 180 0.032
adult behavior GO:0030534 2 0.032
death GO:0016265 121 0.031
cognition GO:0050890 1 0.031
sensory organ development GO:0007423 393 0.031
glial cell proliferation GO:0014009 4 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
lateral inhibition GO:0046331 1 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
Human
positive regulation of apoptotic signaling pathway GO:2001235 1 0.030
protein metabolic process GO:0019538 183 0.030
Human
rna biosynthetic process GO:0032774 181 0.030
Human
maintenance of location GO:0051235 4 0.030
protein targeting to nucleus GO:0044744 3 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.029
Human
cytokinesis GO:0000910 3 0.029
neuron remodeling GO:0016322 1 0.029
embryonic organ development GO:0048568 381 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
positive regulation of signal transduction GO:0009967 56 0.029
regulation of protein import into nucleus GO:0042306 2 0.028
dna metabolic process GO:0006259 27 0.028
Human
regulation of protein complex assembly GO:0043254 3 0.028
single organism metabolic process GO:0044710 217 0.028
Human
transport GO:0006810 220 0.028
negative regulation of tor signaling GO:0032007 2 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
regulation of biological quality GO:0065008 263 0.027
macromolecular complex disassembly GO:0032984 1 0.027
regulation of synapse organization GO:0050807 3 0.027
morphogenesis of an epithelium GO:0002009 333 0.027
positive regulation of cell cycle GO:0045787 3 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
Human
negative regulation of cellular process GO:0048523 283 0.026
Human
macromolecule biosynthetic process GO:0009059 227 0.026
Human
response to stress GO:0006950 263 0.026
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
regulation of reproductive process GO:2000241 4 0.026
stem cell proliferation GO:0072089 4 0.026
protein polymerization GO:0051258 4 0.026
regulation of cellular component organization GO:0051128 86 0.025
amine metabolic process GO:0009308 2 0.025
neuron projection morphogenesis GO:0048812 161 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
blood vessel development GO:0001568 246 0.025
angiogenesis GO:0001525 158 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.025
axonogenesis GO:0007409 152 0.025
cellular component assembly GO:0022607 170 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
cellular response to radiation GO:0071478 4 0.025
regulation of microtubule cytoskeleton organization GO:0070507 3 0.025
single organism transport GO:0044765 206 0.024
microtubule organizing center organization GO:0031023 1 0.024
chemotaxis GO:0006935 104 0.024
male meiosis GO:0007140 2 0.024
cellular response to nutrient levels GO:0031669 2 0.024
response to endogenous stimulus GO:0009719 83 0.024
cellular response to starvation GO:0009267 1 0.024
chemosensory behavior GO:0007635 1 0.024
regulation of synapse assembly GO:0051963 3 0.024
cellular component disassembly GO:0022411 1 0.024
response to organic substance GO:0010033 153 0.023
positive regulation of catabolic process GO:0009896 4 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
Human
cellular amine metabolic process GO:0044106 2 0.022
regulation of organelle assembly GO:1902115 4 0.022
cellular response to endogenous stimulus GO:0071495 68 0.022
protein import into nucleus GO:0006606 3 0.022
sex determination GO:0007530 1 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
Human
cellular response to external stimulus GO:0071496 2 0.022
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
vasculature development GO:0001944 278 0.021
nucleic acid templated transcription GO:0097659 181 0.021
Human
organic substance biosynthetic process GO:1901576 289 0.021
Human
system process GO:0003008 185 0.021
intracellular signal transduction GO:0035556 85 0.021
protein polyubiquitination GO:0000209 4 0.021
Human
regulation of protein targeting GO:1903533 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
cell morphogenesis GO:0000902 289 0.021
protein complex disassembly GO:0043241 1 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.021
cellular response to organic substance GO:0071310 105 0.021
establishment of localization GO:0051234 244 0.021
cellular protein modification process GO:0006464 100 0.020
Human
eye morphogenesis GO:0048592 144 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
triglyceride homeostasis GO:0070328 2 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
Human
regulation of cellular metabolic process GO:0031323 320 0.020
Human
response to hexose GO:0009746 3 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
Human
cell cycle GO:0007049 93 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
Human
positive regulation of biosynthetic process GO:0009891 68 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
regulation of protein catabolic process GO:0042176 1 0.019
macromolecule modification GO:0043412 111 0.019
Human
response to external stimulus GO:0009605 264 0.019
cellular amino acid metabolic process GO:0006520 7 0.018
regulation of glial cell proliferation GO:0060251 4 0.018
neuron development GO:0048666 262 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
regulation of wnt signaling pathway GO:0030111 53 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
camera type eye development GO:0043010 222 0.018
axon development GO:0061564 166 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
negative regulation of developmental process GO:0051093 65 0.018
response to glucose GO:0009749 3 0.018
digestive tract development GO:0048565 265 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
single organism localization GO:1902578 225 0.017
regulation of rna metabolic process GO:0051252 224 0.017
Human
cellular respiration GO:0045333 3 0.017
spermatid development GO:0007286 2 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
positive regulation of rna biosynthetic process GO:1902680 57 0.017
protein heterooligomerization GO:0051291 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
circadian rhythm GO:0007623 19 0.017
intracellular mrna localization GO:0008298 1 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
Human
lipid storage GO:0019915 1 0.016
cytoskeleton organization GO:0007010 96 0.016
negative regulation of gene expression GO:0010629 65 0.016
Human
cellular protein metabolic process GO:0044267 129 0.016
Human
g2 dna damage checkpoint GO:0031572 3 0.016
convergent extension GO:0060026 118 0.016
peptide transport GO:0015833 1 0.016
lipid homeostasis GO:0055088 3 0.016
multi organism process GO:0051704 134 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
chromosome organization involved in meiosis GO:0070192 1 0.016
cell cycle process GO:0022402 53 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
Human
negative regulation of metabolic process GO:0009892 86 0.016
Human
negative regulation of kinase activity GO:0033673 4 0.016
negative regulation of protein complex assembly GO:0031333 1 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.015
brain development GO:0007420 293 0.015
hormone transport GO:0009914 2 0.015
smoothened signaling pathway GO:0007224 30 0.015
female gonad development GO:0008585 4 0.015
cellular ketone metabolic process GO:0042180 11 0.015
protein homooligomerization GO:0051260 3 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
Human
regulation of stem cell differentiation GO:2000736 4 0.015
head development GO:0060322 303 0.014
negative regulation of reproductive process GO:2000242 3 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of binding GO:0051098 3 0.014
developmental programmed cell death GO:0010623 4 0.014
blood vessel morphogenesis GO:0048514 216 0.014
positive regulation of secretion GO:0051047 1 0.014
digestive system development GO:0055123 289 0.014
regulation of molecular function GO:0065009 70 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
positive regulation of signaling GO:0023056 56 0.014
female sex differentiation GO:0046660 4 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
proepicardium development GO:0003342 4 0.014
developmental maturation GO:0021700 34 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
regulation of protein depolymerization GO:1901879 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of apoptotic process GO:0043065 29 0.013
microtubule depolymerization GO:0007019 1 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
positive regulation of cell communication GO:0010647 56 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
histone h3 k4 methylation GO:0051568 2 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
mitotic cell cycle GO:0000278 64 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
oxoacid metabolic process GO:0043436 31 0.013
organic acid metabolic process GO:0006082 31 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
protein dephosphorylation GO:0006470 3 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
Human
positive regulation of striated muscle tissue development GO:0045844 1 0.013
septum transversum development GO:0003343 4 0.013
mitotic cytokinesis GO:0000281 3 0.013
sensory organ morphogenesis GO:0090596 200 0.013
protein modification process GO:0036211 100 0.012
Human
autophagy GO:0006914 4 0.012
response to monosaccharide GO:0034284 3 0.012
cell substrate adhesion GO:0031589 4 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
Human
chromatin modification GO:0016568 21 0.012
Human
central nervous system development GO:0007417 387 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
negative regulation of gliogenesis GO:0014014 1 0.012
negative regulation of signaling GO:0023057 96 0.012
cell cell signaling GO:0007267 52 0.012
negative regulation of cell cycle GO:0045786 14 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
heart development GO:0007507 313 0.012
specification of organ identity GO:0010092 2 0.012
chromatin organization GO:0006325 22 0.012
Human
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
Human
mitotic dna integrity checkpoint GO:0044774 4 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
response to radiation GO:0009314 51 0.012
Human
polarized epithelial cell differentiation GO:0030859 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
dna modification GO:0006304 8 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
immune system process GO:0002376 241 0.012
cell maturation GO:0048469 23 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
negative regulation of cell communication GO:0010648 96 0.011
gastrulation GO:0007369 208 0.011
regulation of response to stimulus GO:0048583 269 0.011
Human
sleep GO:0030431 1 0.011
macroautophagy GO:0016236 1 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
organelle assembly GO:0070925 110 0.011
primary neural tube formation GO:0014020 1 0.011
translational initiation GO:0006413 3 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
meiosis i GO:0007127 1 0.011
cell motility GO:0048870 244 0.011
hormone secretion GO:0046879 2 0.011
regulation of jun kinase activity GO:0043506 3 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
negative regulation of catabolic process GO:0009895 3 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
activation of mapk activity GO:0000187 3 0.011
single organism reproductive process GO:0044702 40 0.011
cellular response to light stimulus GO:0071482 4 0.011
phagocytosis engulfment GO:0006911 1 0.011
chromosome organization GO:0051276 31 0.011
Human
positive regulation of map kinase activity GO:0043406 3 0.011
proteolysis GO:0006508 38 0.011
Human
synaptic growth at neuromuscular junction GO:0051124 2 0.011
positive regulation of translation GO:0045727 1 0.011
positive regulation of molecular function GO:0044093 33 0.011
negative regulation of smoothened signaling pathway GO:0045879 6 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
Human
somatic stem cell maintenance GO:0035019 1 0.011
protein acylation GO:0043543 3 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
rna polyadenylation GO:0043631 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
negative regulation of cell death GO:0060548 60 0.011
cellular protein complex disassembly GO:0043624 1 0.011
response to vitamin GO:0033273 3 0.011
lipid digestion GO:0044241 3 0.011
rna export from nucleus GO:0006405 1 0.011
establishment of localization in cell GO:0051649 77 0.011
positive regulation of rna metabolic process GO:0051254 59 0.010
protein complex biogenesis GO:0070271 30 0.010
centrosome cycle GO:0007098 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
mitochondrion morphogenesis GO:0070584 2 0.010
tube morphogenesis GO:0035239 349 0.010
response to carbohydrate GO:0009743 3 0.010
membrane invagination GO:0010324 1 0.010
actin filament polymerization GO:0030041 2 0.010
taxis GO:0042330 109 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
phosphorylation GO:0016310 69 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
negative regulation of signal transduction GO:0009968 94 0.010
circadian behavior GO:0048512 5 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
regulation of cell cycle process GO:0010564 20 0.010
rna 3 end processing GO:0031123 2 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
negative regulation of defense response GO:0031348 2 0.010
reciprocal meiotic recombination GO:0007131 1 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
regulation of tor signaling GO:0032006 7 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
Human
regulation of organ growth GO:0046620 3 0.010

zgc:55936 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.024
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.010