Danio rerio

0 known processes

LOC100005504

Gig2-like protein DreL

LOC100005504 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
fluid transport GO:0042044 17 0.594
urea transmembrane transport GO:0071918 9 0.394
water transport GO:0006833 15 0.299
one carbon compound transport GO:0019755 14 0.266
ion transmembrane transport GO:0034220 91 0.216
ammonium transmembrane transport GO:0072488 2 0.185
glycerol transport GO:0015793 7 0.140
inorganic anion transport GO:0015698 25 0.129
transmembrane transport GO:0055085 120 0.121
carbon dioxide transmembrane transport GO:0035378 1 0.103
monovalent inorganic cation transport GO:0015672 42 0.101
ion transport GO:0006811 114 0.091
inorganic ion transmembrane transport GO:0098660 57 0.087
carbon dioxide transport GO:0015670 3 0.075
aging GO:0007568 2 0.074
signal transduction GO:0007165 455 0.070
transport GO:0006810 220 0.069
sensory organ development GO:0007423 393 0.068
larval development GO:0002164 2 0.067
single organism transport GO:0044765 206 0.066
eye development GO:0001654 277 0.066
endosome organization GO:0007032 2 0.065
g protein coupled receptor signaling pathway GO:0007186 74 0.064
establishment of localization GO:0051234 244 0.060
immune system process GO:0002376 241 0.057
single organism localization GO:1902578 225 0.056
response to other organism GO:0051707 97 0.054
response to organic substance GO:0010033 153 0.052
polyol transport GO:0015791 7 0.051
response to external stimulus GO:0009605 264 0.049
homeostatic process GO:0042592 142 0.048
maintenance of location GO:0051235 4 0.046
response to chemical GO:0042221 320 0.045
response to glucocorticoid GO:0051384 1 0.044
regulation of metal ion transport GO:0010959 4 0.044
response to stress GO:0006950 263 0.043
response to carbohydrate GO:0009743 3 0.043
multicellular organism growth GO:0035264 4 0.043
camera type eye development GO:0043010 222 0.043
tube morphogenesis GO:0035239 349 0.042
lipid storage GO:0019915 1 0.042
response to monosaccharide GO:0034284 3 0.042
gas transport GO:0015669 3 0.041
anion transport GO:0006820 38 0.041
regulation of biological quality GO:0065008 263 0.040
phagocytosis GO:0006909 3 0.039
cation transmembrane transport GO:0098655 65 0.038
inorganic cation transmembrane transport GO:0098662 50 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.037
regulation of multicellular organismal process GO:0051239 277 0.037
positive regulation of transport GO:0051050 2 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
digestive system development GO:0055123 289 0.034
defense response to other organism GO:0098542 33 0.034
cellular response to hormone stimulus GO:0032870 39 0.034
response to glucose GO:0009749 3 0.032
cation transport GO:0006812 81 0.032
urea transport GO:0015840 11 0.032
multi organism process GO:0051704 134 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
positive regulation of cell cycle GO:0045787 3 0.031
response to biotic stimulus GO:0009607 97 0.031
response to external biotic stimulus GO:0043207 97 0.030
glucose homeostasis GO:0042593 1 0.029
negative regulation of biological process GO:0048519 304 0.028
regulation of cytokine production GO:0001817 3 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
regulation of response to stimulus GO:0048583 269 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
adult behavior GO:0030534 2 0.028
regulation of ph GO:0006885 3 0.028
response to corticosteroid GO:0031960 1 0.027
digestive tract morphogenesis GO:0048546 231 0.027
system process GO:0003008 185 0.027
cellular response to estrogen stimulus GO:0071391 24 0.027
amine metabolic process GO:0009308 2 0.026
positive regulation of catabolic process GO:0009896 4 0.026
rna metabolic process GO:0016070 219 0.026
macromolecule biosynthetic process GO:0009059 227 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
water homeostasis GO:0030104 4 0.025
cellular amine metabolic process GO:0044106 2 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
stem cell proliferation GO:0072089 4 0.024
embryonic organ development GO:0048568 381 0.024
specification of symmetry GO:0009799 204 0.024
gastrulation GO:0007369 208 0.024
heterocycle metabolic process GO:0046483 290 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
response to hexose GO:0009746 3 0.024
regulation of sodium ion transport GO:0002028 2 0.024
cellular ketone metabolic process GO:0042180 11 0.024
gtp metabolic process GO:0046039 4 0.023
biosynthetic process GO:0009058 294 0.023
organic hydroxy compound transport GO:0015850 14 0.023
regulation of tube size GO:0035150 2 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
lipid homeostasis GO:0055088 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
response to nutrient GO:0007584 3 0.022
negative regulation of cytokine production GO:0001818 1 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
stem cell division GO:0017145 1 0.022
response to bacterium GO:0009617 58 0.022
establishment of endothelial barrier GO:0061028 3 0.022
lipid catabolic process GO:0016042 4 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
nuclear transport GO:0051169 4 0.022
positive regulation of immune effector process GO:0002699 3 0.022
sodium ion transport GO:0006814 24 0.022
regulation of response to nutrient levels GO:0032107 1 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cellular response to organic cyclic compound GO:0071407 38 0.021
anion transmembrane transport GO:0098656 12 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
brain development GO:0007420 293 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
carbohydrate homeostasis GO:0033500 1 0.021
cellular response to organic substance GO:0071310 105 0.021
organic substance biosynthetic process GO:1901576 289 0.021
regulation of signal transduction GO:0009966 225 0.021
female sex differentiation GO:0046660 4 0.021
digestive tract development GO:0048565 265 0.021
protein targeting to nucleus GO:0044744 3 0.021
epiboly GO:0090504 41 0.021
regulation of primary metabolic process GO:0080090 311 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.020
neuron neuron synaptic transmission GO:0007270 1 0.020
cellular protein catabolic process GO:0044257 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
regulation of gene expression GO:0010468 265 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
regionalization GO:0003002 274 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of signaling GO:0023051 235 0.020
amide transport GO:0042886 12 0.020
mitochondrion organization GO:0007005 4 0.020
positive regulation of biological process GO:0048518 253 0.020
cellular response to starvation GO:0009267 1 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
defense response to bacterium GO:0042742 22 0.019
nuclear import GO:0051170 3 0.019
nucleic acid templated transcription GO:0097659 181 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
head development GO:0060322 303 0.019
heart contraction GO:0060047 71 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
renal absorption GO:0070293 1 0.019
carbohydrate transport GO:0008643 13 0.019
stem cell maintenance GO:0019827 4 0.019
long chain fatty acid metabolic process GO:0001676 1 0.019
regulation of blood vessel size GO:0050880 2 0.019
regulation of cell activation GO:0050865 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
locomotion GO:0040011 313 0.018
protein import into nucleus GO:0006606 3 0.018
organelle organization GO:0006996 227 0.018
multicellular organismal water homeostasis GO:0050891 1 0.018
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.018
protein import GO:0017038 3 0.018
single organism nuclear import GO:1902593 3 0.018
cellular response to nutrient levels GO:0031669 2 0.018
gene expression GO:0010467 252 0.018
peptide transport GO:0015833 1 0.018
regulation of binding GO:0051098 3 0.018
pericardium development GO:0060039 1 0.018
protein secretion GO:0009306 1 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of developmental process GO:0050793 247 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
negative regulation of catabolic process GO:0009895 3 0.017
regulation of biosynthetic process GO:0009889 250 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
small molecule metabolic process GO:0044281 77 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
germ line stem cell maintenance GO:0030718 2 0.017
cellular component biogenesis GO:0044085 178 0.017
determination of left right symmetry GO:0007368 179 0.017
developmental growth GO:0048589 166 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
somatic muscle development GO:0007525 4 0.017
heart development GO:0007507 313 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
vasculature development GO:0001944 278 0.017
regulation of cellular ph GO:0030641 1 0.017
phosphatidylinositol mediated signaling GO:0048015 2 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
regulation of gtpase activity GO:0043087 2 0.016
organic substance transport GO:0071702 58 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
regulation of protein complex assembly GO:0043254 3 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
tissue remodeling GO:0048771 4 0.016
central nervous system development GO:0007417 387 0.016
negative regulation of cellular process GO:0048523 283 0.016
gtp catabolic process GO:0006184 2 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
positive regulation of blood circulation GO:1903524 2 0.016
retina development in camera type eye GO:0060041 146 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
compound eye development GO:0048749 2 0.016
regulation of rna metabolic process GO:0051252 224 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cellular biosynthetic process GO:0044249 286 0.016
regulation of metabolic process GO:0019222 359 0.016
regulation of blood pressure GO:0008217 1 0.016
hormone transport GO:0009914 2 0.016
regulation of intracellular ph GO:0051453 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
synaptic transmission cholinergic GO:0007271 4 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
positive regulation of secretion GO:0051047 1 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
response to salt stress GO:0009651 10 0.016
spermatid development GO:0007286 2 0.016
female gonad development GO:0008585 4 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
positive regulation of cytokine production GO:0001819 2 0.016
fatty acid transport GO:0015908 1 0.015
negative regulation of defense response GO:0031348 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
spermatid differentiation GO:0048515 2 0.015
ovulation cycle process GO:0022602 2 0.015
dicarboxylic acid transport GO:0006835 1 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
neuromast development GO:0048884 46 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
cellular response to external stimulus GO:0071496 2 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
blood vessel development GO:0001568 246 0.015
autophagy GO:0006914 4 0.015
regulation of reproductive process GO:2000241 4 0.015
cell morphogenesis GO:0000902 289 0.015
transcription dna templated GO:0006351 181 0.015
hormone secretion GO:0046879 2 0.015
sensory system development GO:0048880 76 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
protein localization to nucleus GO:0034504 3 0.015
response to vitamin GO:0033273 3 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of synaptic plasticity GO:0048167 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
sensory organ morphogenesis GO:0090596 200 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
long chain fatty acid transport GO:0015909 1 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
hatching GO:0035188 4 0.014
determination of bilateral symmetry GO:0009855 204 0.014
protein homooligomerization GO:0051260 3 0.014
regulation of inflammatory response GO:0050727 2 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
protein acetylation GO:0006473 2 0.014
meiotic nuclear division GO:0007126 4 0.014
cellular component morphogenesis GO:0032989 336 0.014
lateral line system development GO:0048925 76 0.014
kidney development GO:0001822 92 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
hemopoiesis GO:0030097 183 0.014
single organism organelle organization GO:1902589 199 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
blood circulation GO:0008015 87 0.014
chloride transmembrane transport GO:1902476 4 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
embryonic heart tube development GO:0035050 133 0.014
ph reduction GO:0045851 1 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
chordate embryonic development GO:0043009 271 0.014
cellular component assembly GO:0022607 170 0.013
somite development GO:0061053 96 0.013
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
macroautophagy GO:0016236 1 0.013
interspecies interaction between organisms GO:0044419 4 0.013
negative regulation of secretion GO:0051048 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
regulation of autophagy GO:0010506 3 0.013
neurological system process GO:0050877 62 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
leukocyte proliferation GO:0070661 1 0.013
immune response GO:0006955 28 0.013
single organism membrane fusion GO:0044801 2 0.013
renal system development GO:0072001 94 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
heart looping GO:0001947 94 0.013
golgi vesicle transport GO:0048193 3 0.013
protein metabolic process GO:0019538 183 0.013
lymphocyte proliferation GO:0046651 1 0.013
toxin transport GO:1901998 2 0.013
regulation of circadian rhythm GO:0042752 4 0.013
fertilization GO:0009566 3 0.013
regulation of transporter activity GO:0032409 2 0.013
generation of neurons GO:0048699 385 0.013
nitrogen compound transport GO:0071705 23 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
cellular response to lipid GO:0071396 39 0.013
endocrine process GO:0050886 2 0.013
urogenital system development GO:0001655 97 0.013
single fertilization GO:0007338 3 0.013
regulation of photoreceptor cell differentiation GO:0046532 2 0.012
membrane invagination GO:0010324 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
inner ear development GO:0048839 126 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
response to amino acid GO:0043200 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of protein transport GO:0051223 3 0.012
positive regulation of cell killing GO:0031343 2 0.012
protein acylation GO:0043543 3 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
superoxide metabolic process GO:0006801 2 0.012
response to wounding GO:0009611 116 0.012
negative regulation of gene expression GO:0010629 65 0.012
intracellular signal transduction GO:0035556 85 0.012
phagocytosis engulfment GO:0006911 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
regulation of organ growth GO:0046620 3 0.012
cellular aldehyde metabolic process GO:0006081 4 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
positive regulation of cell division GO:0051781 2 0.012
eye morphogenesis GO:0048592 144 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
atp catabolic process GO:0006200 4 0.012
response to endogenous stimulus GO:0009719 83 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
lateral line development GO:0048882 66 0.012
ear development GO:0043583 127 0.012
organic acid metabolic process GO:0006082 31 0.012
cellular lipid catabolic process GO:0044242 3 0.012
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
circadian sleep wake cycle GO:0042745 2 0.011
chemical homeostasis GO:0048878 49 0.011
sex determination GO:0007530 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
peptidyl serine modification GO:0018209 2 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
insulin like growth factor receptor signaling pathway GO:0048009 4 0.011
gland development GO:0048732 143 0.011
response to topologically incorrect protein GO:0035966 2 0.011
response to uv GO:0009411 3 0.011
regulation of p38mapk cascade GO:1900744 1 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
tyrosine phosphorylation of stat protein GO:0007260 1 0.011
cellular component movement GO:0006928 335 0.011
defense response GO:0006952 47 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
somitogenesis GO:0001756 87 0.011
b cell activation GO:0042113 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of transcription dna templated GO:0006355 213 0.011
regulation of protein targeting GO:1903533 2 0.011
positive regulation of cellular process GO:0048522 201 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
complement activation GO:0006956 3 0.011
metal ion transport GO:0030001 58 0.011
cellular component disassembly GO:0022411 1 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
heart process GO:0003015 71 0.010
rna localization GO:0006403 4 0.010
muscle structure development GO:0061061 196 0.010
multicellular organismal response to stress GO:0033555 2 0.010
epithelial cell differentiation GO:0030855 116 0.010
regulation of lipid transport GO:0032368 4 0.010
cellular response to steroid hormone stimulus GO:0071383 31 0.010
pyruvate metabolic process GO:0006090 1 0.010
circulatory system process GO:0003013 87 0.010
segmentation GO:0035282 97 0.010
acylglycerol homeostasis GO:0055090 2 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
response to lipid GO:0033993 60 0.010
anterior posterior pattern specification GO:0009952 152 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
single organism metabolic process GO:0044710 217 0.010
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.010
kidney epithelium development GO:0072073 23 0.010
regulation of receptor activity GO:0010469 2 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
endosomal transport GO:0016197 2 0.010
growth GO:0040007 174 0.010
double strand break repair GO:0006302 3 0.010
response to hormone GO:0009725 48 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
p38mapk cascade GO:0038066 1 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
cell migration GO:0016477 237 0.010

LOC100005504 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010