Danio rerio

0 known processes

ctrb1

chymotrypsinogen B1

(Aliases: wu:fb61f07,wu:fb69e12)

ctrb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to amine GO:0014075 1 0.253
heart development GO:0007507 313 0.146
multicellular organism growth GO:0035264 4 0.138
response to alkaloid GO:0043279 2 0.118
single organism localization GO:1902578 225 0.090
meiotic chromosome segregation GO:0045132 3 0.087
aging GO:0007568 2 0.084
diterpenoid metabolic process GO:0016101 15 0.078
spermatid differentiation GO:0048515 2 0.071
synaptic target recognition GO:0008039 1 0.070
larval development GO:0002164 2 0.067
regulation of multicellular organism growth GO:0040014 4 0.065
zymogen activation GO:0031638 3 0.060
generation of neurons GO:0048699 385 0.057
localization of cell GO:0051674 244 0.055
response to amphetamine GO:0001975 1 0.054
response to nicotine GO:0035094 2 0.054
organic cyclic compound metabolic process GO:1901360 301 0.051
signal transduction GO:0007165 455 0.051
regulation of autophagy GO:0010506 3 0.049
dicarboxylic acid transport GO:0006835 1 0.049
cellular ketone metabolic process GO:0042180 11 0.046
autophagy GO:0006914 4 0.046
cell migration GO:0016477 237 0.043
digestive system development GO:0055123 289 0.043
response to glucocorticoid GO:0051384 1 0.040
regulation of organ growth GO:0046620 3 0.040
positive regulation of transport GO:0051050 2 0.040
small molecule catabolic process GO:0044282 3 0.040
endothelial cell migration GO:0043542 19 0.038
peripheral nervous system development GO:0007422 55 0.038
response to organic substance GO:0010033 153 0.037
astrocyte differentiation GO:0048708 1 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.035
neuron development GO:0048666 262 0.034
monoamine transport GO:0015844 1 0.034
response to chemical GO:0042221 320 0.033
establishment of localization GO:0051234 244 0.033
epithelium migration GO:0090132 25 0.033
nucleic acid metabolic process GO:0090304 244 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.032
adult behavior GO:0030534 2 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
regulation of signal transduction GO:0009966 225 0.032
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.031
cellular component movement GO:0006928 335 0.031
muscle structure development GO:0061061 196 0.031
endosomal transport GO:0016197 2 0.030
biosynthetic process GO:0009058 294 0.030
transport GO:0006810 220 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
central nervous system development GO:0007417 387 0.030
single organism organelle organization GO:1902589 199 0.030
cell motility GO:0048870 244 0.030
cellular hormone metabolic process GO:0034754 19 0.030
terpenoid metabolic process GO:0006721 15 0.029
positive regulation of epithelial cell differentiation GO:0030858 2 0.029
small molecule metabolic process GO:0044281 77 0.029
transcription dna templated GO:0006351 181 0.029
gtp catabolic process GO:0006184 2 0.029
nucleic acid templated transcription GO:0097659 181 0.029
cell projection organization GO:0030030 284 0.028
neuron differentiation GO:0030182 353 0.028
rna metabolic process GO:0016070 219 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
heart morphogenesis GO:0003007 156 0.027
mitochondrion organization GO:0007005 4 0.027
meiotic nuclear division GO:0007126 4 0.027
regulation of cytokine production GO:0001817 3 0.027
regulation of tube size GO:0035150 2 0.027
female meiotic division GO:0007143 2 0.027
cellular macromolecule metabolic process GO:0044260 391 0.026
response to ketone GO:1901654 1 0.026
olfactory bulb development GO:0021772 4 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
regulation of developmental process GO:0050793 247 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
regulation of blood vessel size GO:0050880 2 0.026
muscle cell differentiation GO:0042692 139 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
regulation of hormone secretion GO:0046883 2 0.026
response to wounding GO:0009611 116 0.026
amine metabolic process GO:0009308 2 0.026
cellular amine metabolic process GO:0044106 2 0.026
digestive tract development GO:0048565 265 0.025
kidney development GO:0001822 92 0.025
regulation of blood pressure GO:0008217 1 0.025
primary alcohol metabolic process GO:0034308 7 0.025
negative regulation of cellular process GO:0048523 283 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
glucose homeostasis GO:0042593 1 0.025
regulation of rna biosynthetic process GO:2001141 213 0.025
regeneration GO:0031099 91 0.025
regulation of cell communication GO:0010646 232 0.024
regulation of signaling GO:0023051 235 0.024
locomotion GO:0040011 313 0.024
protein metabolic process GO:0019538 183 0.024
ameboidal type cell migration GO:0001667 143 0.024
chordate embryonic development GO:0043009 271 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
nuclear transport GO:0051169 4 0.024
regulation of cell shape GO:0008360 1 0.024
regulation of rna metabolic process GO:0051252 224 0.023
endocrine process GO:0050886 2 0.023
regulation of biosynthetic process GO:0009889 250 0.023
exocrine pancreas development GO:0031017 28 0.023
organelle assembly GO:0070925 110 0.023
positive regulation of biological process GO:0048518 253 0.023
regulation of response to stimulus GO:0048583 269 0.023
tube morphogenesis GO:0035239 349 0.023
organonitrogen compound metabolic process GO:1901564 74 0.022
growth GO:0040007 174 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
response to endogenous stimulus GO:0009719 83 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
death GO:0016265 121 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
determination of bilateral symmetry GO:0009855 204 0.022
cellular biosynthetic process GO:0044249 286 0.022
embryonic viscerocranium morphogenesis GO:0048703 52 0.022
wnt signaling pathway GO:0016055 80 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
regulation of binding GO:0051098 3 0.021
neurotransmitter secretion GO:0007269 2 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.021
organic substance biosynthetic process GO:1901576 289 0.021
muscle cell development GO:0055001 115 0.021
cell projection morphogenesis GO:0048858 244 0.021
response to organic cyclic compound GO:0014070 51 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
interspecies interaction between organisms GO:0044419 4 0.020
positive regulation of secretion GO:0051047 1 0.020
single organism transport GO:0044765 206 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
actin filament based movement GO:0030048 1 0.020
smooth muscle contraction GO:0006939 2 0.020
response to corticosteroid GO:0031960 1 0.020
positive regulation of epithelial cell migration GO:0010634 2 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.020
tissue migration GO:0090130 37 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
positive regulation of cellular process GO:0048522 201 0.019
organelle organization GO:0006996 227 0.019
protein secretion GO:0009306 1 0.019
phagocytosis GO:0006909 3 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
cell part morphogenesis GO:0032990 246 0.019
apical junction assembly GO:0043297 1 0.019
cellular response to organic substance GO:0071310 105 0.019
response to drug GO:0042493 3 0.019
embryonic organ morphogenesis GO:0048562 274 0.018
pancreas development GO:0031016 84 0.018
response to stress GO:0006950 263 0.018
female meiosis chromosome segregation GO:0016321 1 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
carbohydrate homeostasis GO:0033500 1 0.018
developmental growth GO:0048589 166 0.018
response to steroid hormone GO:0048545 35 0.018
cellular component morphogenesis GO:0032989 336 0.018
lipid catabolic process GO:0016042 4 0.018
regulation of reproductive process GO:2000241 4 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
cell morphogenesis GO:0000902 289 0.017
protein modification process GO:0036211 100 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
wound healing GO:0042060 90 0.017
regulation of protein transport GO:0051223 3 0.017
epiboly GO:0090504 41 0.017
cellular response to external stimulus GO:0071496 2 0.017
hormone secretion GO:0046879 2 0.017
retinoid metabolic process GO:0001523 15 0.017
regulation of hormone levels GO:0010817 21 0.017
hemopoiesis GO:0030097 183 0.017
apoptotic process GO:0006915 116 0.017
specification of symmetry GO:0009799 204 0.017
ovulation cycle GO:0042698 2 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
neurotransmitter transport GO:0006836 2 0.017
response to external stimulus GO:0009605 264 0.017
positive regulation of translation GO:0045727 1 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
hindbrain development GO:0030902 91 0.016
regionalization GO:0003002 274 0.016
response to glucose GO:0009749 3 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
tissue regeneration GO:0042246 74 0.016
behavior GO:0007610 74 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
er nucleus signaling pathway GO:0006984 2 0.016
vasculature development GO:0001944 278 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
gene expression GO:0010467 252 0.015
regulation of primary metabolic process GO:0080090 311 0.015
gastrulation GO:0007369 208 0.015
cellular component disassembly GO:0022411 1 0.015
rna biosynthetic process GO:0032774 181 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
olfactory lobe development GO:0021988 4 0.015
multi organism reproductive process GO:0044703 36 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
protein targeting to nucleus GO:0044744 3 0.015
negative regulation of dna replication GO:0008156 2 0.015
isoprenoid metabolic process GO:0006720 15 0.015
regulation of protein binding GO:0043393 3 0.015
nuclear import GO:0051170 3 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
heterocycle metabolic process GO:0046483 290 0.015
type b pancreatic cell development GO:0003323 4 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
glial cell migration GO:0008347 3 0.015
oocyte maturation GO:0001556 4 0.015
positive regulation of catabolic process GO:0009896 4 0.015
positive regulation of gene expression GO:0010628 71 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
striated muscle cell development GO:0055002 108 0.015
response to hexose GO:0009746 3 0.014
head development GO:0060322 303 0.014
skeletal muscle organ development GO:0060538 78 0.014
neuroblast proliferation GO:0007405 2 0.014
hindbrain morphogenesis GO:0021575 22 0.014
regulation of heart growth GO:0060420 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
positive regulation of muscle organ development GO:0048636 1 0.014
cognition GO:0050890 1 0.014
reproductive process GO:0022414 40 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of cell activation GO:0050865 1 0.014
steroid metabolic process GO:0008202 7 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
positive regulation of cytokine production GO:0001819 2 0.014
epithelial cell development GO:0002064 42 0.014
cellular response to methanol GO:0071405 4 0.013
heart valve formation GO:0003188 4 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
single organism nuclear import GO:1902593 3 0.013
hepaticobiliary system development GO:0061008 98 0.013
proteolysis GO:0006508 38 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
cellular component biogenesis GO:0044085 178 0.013
brain development GO:0007420 293 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
energy reserve metabolic process GO:0006112 2 0.013
exocytosis GO:0006887 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of mesenchymal cell proliferation GO:0010464 1 0.013
tissue remodeling GO:0048771 4 0.013
viral process GO:0016032 1 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
embryonic heart tube development GO:0035050 133 0.013
cellular component assembly GO:0022607 170 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
regulation of biological quality GO:0065008 263 0.013
embryonic organ development GO:0048568 381 0.013
protein polymerization GO:0051258 4 0.013
hormone metabolic process GO:0042445 19 0.013
ribosome assembly GO:0042255 1 0.013
organic heteropentacyclic compound metabolic process GO:1901376 1 0.013
negative regulation of biological process GO:0048519 304 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
response to methanol GO:0033986 4 0.013
regulation of metabolic process GO:0019222 359 0.013
system process GO:0003008 185 0.013
central nervous system myelination GO:0022010 2 0.013
lateral inhibition GO:0046331 1 0.013
regulation of gene expression GO:0010468 265 0.013
cellular protein catabolic process GO:0044257 4 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
sensory organ development GO:0007423 393 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
cardiac atrium development GO:0003230 4 0.012
negative regulation of reproductive process GO:2000242 3 0.012
regulation of protein complex assembly GO:0043254 3 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
maintenance of location GO:0051235 4 0.012
immune system process GO:0002376 241 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
dendrite guidance GO:0070983 0 0.012
macromolecule modification GO:0043412 111 0.012
regulation of inflammatory response GO:0050727 2 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
renal system development GO:0072001 94 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
neuron recognition GO:0008038 18 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
oxoacid metabolic process GO:0043436 31 0.012
regulation of calcium ion transport GO:0051924 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
rna localization GO:0006403 4 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
determination of left right symmetry GO:0007368 179 0.012
cell matrix adhesion GO:0007160 4 0.012
macromolecular complex disassembly GO:0032984 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
response to vitamin GO:0033273 3 0.012
cellular response to starvation GO:0009267 1 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
lamellipodium organization GO:0097581 1 0.011
activation of mapk activity GO:0000187 3 0.011
regulation of mrna processing GO:0050684 3 0.011
neuron fate determination GO:0048664 2 0.011
epidermal cell fate specification GO:0009957 4 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
auditory receptor cell fate determination GO:0042668 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
response to alcohol GO:0097305 14 0.011
fin regeneration GO:0031101 51 0.011
urogenital system development GO:0001655 97 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
cell adhesion GO:0007155 40 0.011
blood vessel development GO:0001568 246 0.011
heart looping GO:0001947 94 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
forebrain development GO:0030900 96 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
peptidyl serine modification GO:0018209 2 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
intramembranous ossification GO:0001957 3 0.010
multicellular organismal response to stress GO:0033555 2 0.010
protein import into nucleus GO:0006606 3 0.010
cell substrate adhesion GO:0031589 4 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
negative regulation of cytokine production GO:0001818 1 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
response to uv GO:0009411 3 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
meiosis i GO:0007127 1 0.010
eye morphogenesis GO:0048592 144 0.010
fertilization GO:0009566 3 0.010
stem cell proliferation GO:0072089 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
macromolecule deacylation GO:0098732 3 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
response to salt stress GO:0009651 10 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
activation of jun kinase activity GO:0007257 2 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010

ctrb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
maturity onset diabetes of the young DOID:0050524 0 0.020
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016