Danio rerio

0 known processes

prdm8

PR domain containing 8

(Aliases: wu:fd12b11,prdm8a,zgc:63680)

prdm8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.317
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.189
Mouse
regulation of transcription dna templated GO:0006355 213 0.163
Mouse
rna metabolic process GO:0016070 219 0.145
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.128
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.127
Mouse
gene expression GO:0010467 252 0.122
Mouse
regulation of metabolic process GO:0019222 359 0.118
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.111
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.108
Mouse
heterocycle metabolic process GO:0046483 290 0.107
Mouse
regulation of biosynthetic process GO:0009889 250 0.107
Mouse
negative regulation of cellular process GO:0048523 283 0.106
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.102
Mouse
sensory organ development GO:0007423 393 0.101
macromolecule biosynthetic process GO:0009059 227 0.099
Mouse
nucleic acid metabolic process GO:0090304 244 0.094
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.094
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.091
Mouse
cellular biosynthetic process GO:0044249 286 0.090
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.089
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.088
Mouse
rna biosynthetic process GO:0032774 181 0.088
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.079
Mouse
neuron differentiation GO:0030182 353 0.079
organic substance biosynthetic process GO:1901576 289 0.076
Mouse
regulation of gene expression GO:0010468 265 0.073
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.073
morphogenesis of an epithelium GO:0002009 333 0.070
cell fate commitment GO:0045165 99 0.068
larval development GO:0002164 2 0.067
regulation of cellular metabolic process GO:0031323 320 0.066
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.066
guanosine containing compound metabolic process GO:1901068 4 0.061
central nervous system development GO:0007417 387 0.060
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.059
gtp metabolic process GO:0046039 4 0.059
positive regulation of cellular process GO:0048522 201 0.059
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.059
heterocycle biosynthetic process GO:0018130 215 0.058
Mouse
eye development GO:0001654 277 0.058
positive regulation of biological process GO:0048518 253 0.058
Mouse
regulation of rna metabolic process GO:0051252 224 0.058
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.057
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.056
Mouse
phagocytosis GO:0006909 3 0.055
neuron development GO:0048666 262 0.054
cellular aromatic compound metabolic process GO:0006725 295 0.053
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.053
Mouse
biosynthetic process GO:0009058 294 0.052
Mouse
cell motility GO:0048870 244 0.052
nucleic acid templated transcription GO:0097659 181 0.050
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
Mouse
lipid catabolic process GO:0016042 4 0.048
negative regulation of gene expression GO:0010629 65 0.048
Mouse
regulation of cell communication GO:0010646 232 0.047
transcription dna templated GO:0006351 181 0.047
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.047
Mouse
generation of neurons GO:0048699 385 0.046
Mouse
nitrogen compound metabolic process GO:0006807 319 0.046
Mouse
regulation of response to stimulus GO:0048583 269 0.046
brain development GO:0007420 293 0.045
regulation of signaling GO:0023051 235 0.045
regulation of primary metabolic process GO:0080090 311 0.045
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.044
regulation of nervous system development GO:0051960 90 0.043
Mouse
camera type eye development GO:0043010 222 0.042
head development GO:0060322 303 0.041
negative regulation of biological process GO:0048519 304 0.040
Mouse
renal system development GO:0072001 94 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
Mouse
regionalization GO:0003002 274 0.040
cell projection organization GO:0030030 284 0.039
cellular response to external stimulus GO:0071496 2 0.039
muscle structure development GO:0061061 196 0.039
regulation of circadian rhythm GO:0042752 4 0.038
positive regulation of metabolic process GO:0009893 108 0.038
aging GO:0007568 2 0.037
negative regulation of rna metabolic process GO:0051253 48 0.037
Mouse
maintenance of location GO:0051235 4 0.036
positive regulation of cell cycle GO:0045787 3 0.035
positive regulation of catabolic process GO:0009896 4 0.035
regulation of cell matrix adhesion GO:0001952 1 0.033
establishment of localization GO:0051234 244 0.033
gtp catabolic process GO:0006184 2 0.033
stem cell differentiation GO:0048863 117 0.033
fin development GO:0033333 77 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
gland development GO:0048732 143 0.031
nuclear import GO:0051170 3 0.031
regulation of biological quality GO:0065008 263 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
adult behavior GO:0030534 2 0.030
cellular component morphogenesis GO:0032989 336 0.030
startle response GO:0001964 4 0.029
vasculature development GO:0001944 278 0.029
mesenchyme development GO:0060485 127 0.029
synaptic target recognition GO:0008039 1 0.028
protein targeting to nucleus GO:0044744 3 0.028
negative regulation of metabolic process GO:0009892 86 0.028
Mouse
oligodendrocyte differentiation GO:0048709 23 0.028
Mouse
protein import into nucleus GO:0006606 3 0.028
response to carbohydrate GO:0009743 3 0.028
regulation of neurogenesis GO:0050767 87 0.028
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.027
response to chemical GO:0042221 320 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
internal protein amino acid acetylation GO:0006475 2 0.027
retina development in camera type eye GO:0060041 146 0.027
regulation of dendrite development GO:0050773 3 0.027
sensory perception of pain GO:0019233 1 0.027
cell part morphogenesis GO:0032990 246 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
positive regulation of transport GO:0051050 2 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of ion transmembrane transporter activity GO:0032412 2 0.026
localization of cell GO:0051674 244 0.025
positive regulation of cytokine production GO:0001819 2 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
single organism localization GO:1902578 225 0.025
cellular ketone metabolic process GO:0042180 11 0.025
transmission of nerve impulse GO:0019226 19 0.025
phagocytosis engulfment GO:0006911 1 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
Mouse
regulation of protein transport GO:0051223 3 0.025
response to external stimulus GO:0009605 264 0.025
regulation of transporter activity GO:0032409 2 0.025
regulation of multicellular organismal development GO:2000026 223 0.024
Mouse
ion transport GO:0006811 114 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
regulation of signal transduction GO:0009966 225 0.024
positive regulation of gtpase activity GO:0043547 1 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
regulation of protein targeting GO:1903533 2 0.023
transmembrane transport GO:0055085 120 0.023
cell substrate adhesion GO:0031589 4 0.023
neuron projection development GO:0031175 180 0.023
amine metabolic process GO:0009308 2 0.023
negative regulation of gliogenesis GO:0014014 1 0.023
neuron projection morphogenesis GO:0048812 161 0.023
embryonic heart tube development GO:0035050 133 0.023
cell matrix adhesion GO:0007160 4 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
nuclear transport GO:0051169 4 0.022
positive regulation of ras protein signal transduction GO:0046579 1 0.022
negative regulation of transcription dna templated GO:0045892 45 0.022
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.022
pectoral fin development GO:0033339 50 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
response to alkaloid GO:0043279 2 0.022
regulation of dendrite morphogenesis GO:0048814 3 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
stem cell proliferation GO:0072089 4 0.022
kidney development GO:0001822 92 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
response to monosaccharide GO:0034284 3 0.021
signal transduction GO:0007165 455 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
embryonic organ development GO:0048568 381 0.021
single organism nuclear import GO:1902593 3 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
protein import GO:0017038 3 0.021
regulation of cellular component organization GO:0051128 86 0.021
heart development GO:0007507 313 0.021
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.020
peptidyl serine modification GO:0018209 2 0.020
determination of bilateral symmetry GO:0009855 204 0.020
positive regulation of gene expression GO:0010628 71 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
neuron neuron synaptic transmission GO:0007270 1 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of metal ion transport GO:0010959 4 0.020
urogenital system development GO:0001655 97 0.020
intracellular receptor signaling pathway GO:0030522 30 0.020
axon ensheathment in central nervous system GO:0032291 2 0.020
positive regulation of rna biosynthetic process GO:1902680 57 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
water homeostasis GO:0030104 4 0.019
sleep GO:0030431 1 0.019
membrane invagination GO:0010324 1 0.019
cellular component assembly GO:0022607 170 0.019
protein localization to nucleus GO:0034504 3 0.019
action potential GO:0001508 19 0.019
regulation of cell activation GO:0050865 1 0.019
neurological system process GO:0050877 62 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
Mouse
regulation of protein catabolic process GO:0042176 1 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
locomotion GO:0040011 313 0.019
specification of symmetry GO:0009799 204 0.019
camera type eye morphogenesis GO:0048593 108 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
blood vessel development GO:0001568 246 0.018
appendage development GO:0048736 80 0.018
chordate embryonic development GO:0043009 271 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
protein acylation GO:0043543 3 0.018
response to stress GO:0006950 263 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of cell development GO:0060284 100 0.018
Mouse
cell fate specification GO:0001708 68 0.018
cellular amine metabolic process GO:0044106 2 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
Mouse
homeostatic process GO:0042592 142 0.017
digestive system development GO:0055123 289 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
single organism transport GO:0044765 206 0.017
central nervous system neuron differentiation GO:0021953 74 0.017
oligodendrocyte development GO:0014003 7 0.017
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
Mouse
transport GO:0006810 220 0.017
system process GO:0003008 185 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
ion transmembrane transport GO:0034220 91 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
Mouse
cellular component movement GO:0006928 335 0.017
regulation of neuron differentiation GO:0045664 56 0.017
response to abiotic stimulus GO:0009628 122 0.017
regulation of dna replication GO:0006275 3 0.017
epithelial cell differentiation GO:0030855 116 0.016
cognition GO:0050890 1 0.016
regulation of skeletal muscle tissue development GO:0048641 4 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
convergent extension GO:0060026 118 0.016
lipid storage GO:0019915 1 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
Mouse
single organism metabolic process GO:0044710 217 0.016
determination of left right symmetry GO:0007368 179 0.016
response to external biotic stimulus GO:0043207 97 0.016
antimicrobial humoral response GO:0019730 2 0.016
regulation of glial cell differentiation GO:0045685 4 0.016
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
response to biotic stimulus GO:0009607 97 0.016
brain morphogenesis GO:0048854 18 0.016
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of gtpase activity GO:0043087 2 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
striated muscle tissue development GO:0014706 110 0.015
cellular response to oxygen levels GO:0071453 1 0.015
positive regulation of signaling GO:0023056 56 0.015
positive regulation of cell activation GO:0050867 1 0.015
fertilization GO:0009566 3 0.015
compound eye development GO:0048749 2 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
glial cell development GO:0021782 20 0.015
Mouse
locomotor rhythm GO:0045475 3 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.015
multicellular organism growth GO:0035264 4 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
peptidyl serine phosphorylation GO:0018105 1 0.014
multicellular organismal signaling GO:0035637 22 0.014
negative regulation of cell communication GO:0010648 96 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
response to hexose GO:0009746 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
female sex differentiation GO:0046660 4 0.014
regulation of cytokine production GO:0001817 3 0.014
hepaticobiliary system development GO:0061008 98 0.014
spermatid differentiation GO:0048515 2 0.014
proximal distal pattern formation GO:0009954 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
Mouse
cell migration GO:0016477 237 0.014
heart morphogenesis GO:0003007 156 0.014
amino acid transport GO:0006865 2 0.013
meiotic nuclear division GO:0007126 4 0.013
positive regulation of cell communication GO:0010647 56 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
blood vessel morphogenesis GO:0048514 216 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
Mouse
positive regulation of response to stimulus GO:0048584 80 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
positive regulation of secretion GO:0051047 1 0.013
skeletal system morphogenesis GO:0048705 102 0.013
eye morphogenesis GO:0048592 144 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
response to glucose GO:0009749 3 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
protein acetylation GO:0006473 2 0.013
protein secretion GO:0009306 1 0.013
cellular protein catabolic process GO:0044257 4 0.013
glial cell differentiation GO:0010001 42 0.013
Mouse
negative regulation of response to stimulus GO:0048585 104 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
autophagy GO:0006914 4 0.013
astrocyte differentiation GO:0048708 1 0.013
mesenchymal cell differentiation GO:0048762 87 0.012
cytokinesis GO:0000910 3 0.012
response to amphetamine GO:0001975 1 0.012
multi organism process GO:0051704 134 0.012
response to organic cyclic compound GO:0014070 51 0.012
regulation of synapse assembly GO:0051963 3 0.012
cellular response to nutrient levels GO:0031669 2 0.012
regulation of sodium ion transport GO:0002028 2 0.012
cellular localization GO:0051641 97 0.012
protein metabolic process GO:0019538 183 0.012
post embryonic organ development GO:0048569 4 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
regulation of apoptotic process GO:0042981 98 0.012
axonogenesis GO:0007409 152 0.012
muscle cell differentiation GO:0042692 139 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of reproductive process GO:2000241 4 0.012
central nervous system myelination GO:0022010 2 0.012
response to lipid GO:0033993 60 0.012
spermatid development GO:0007286 2 0.012
sequestering of metal ion GO:0051238 3 0.012
ameboidal type cell migration GO:0001667 143 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
skeletal system development GO:0001501 181 0.012
negative regulation of developmental process GO:0051093 65 0.012
neuronal action potential GO:0019228 18 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
regulation of membrane potential GO:0042391 23 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
forebrain development GO:0030900 96 0.011
regulation of cell projection organization GO:0031344 44 0.011
response to ketone GO:1901654 1 0.011
endosomal transport GO:0016197 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
regulation of neurological system process GO:0031644 2 0.011
regulation of developmental process GO:0050793 247 0.011
Mouse
negative regulation of signal transduction GO:0009968 94 0.011
ventral spinal cord development GO:0021517 35 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
regulation of blood pressure GO:0008217 1 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
protein stabilization GO:0050821 2 0.011
cell cell signaling GO:0007267 52 0.011
female gonad development GO:0008585 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
nuclear migration GO:0007097 3 0.011
regulation of ph GO:0006885 3 0.011
regulation of molecular function GO:0065009 70 0.011
immune system process GO:0002376 241 0.011
single organism organelle organization GO:1902589 199 0.011
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
cell cycle arrest GO:0007050 1 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.010
interspecies interaction between organisms GO:0044419 4 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
stem cell division GO:0017145 1 0.010
response to other organism GO:0051707 97 0.010
skeletal muscle organ development GO:0060538 78 0.010
organelle organization GO:0006996 227 0.010
muscle tissue development GO:0060537 110 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
neural crest cell differentiation GO:0014033 72 0.010
neuron migration GO:0001764 22 0.010
negative regulation of catabolic process GO:0009895 3 0.010
peptidyl threonine modification GO:0018210 1 0.010
intracellular signal transduction GO:0035556 85 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
regulation of binding GO:0051098 3 0.010
behavior GO:0007610 74 0.010
positive regulation of ras gtpase activity GO:0032320 1 0.010
mitochondrion organization GO:0007005 4 0.010

prdm8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.011
nervous system disease DOID:863 0 0.011
cardiovascular system disease DOID:1287 0 0.010