Danio rerio

0 known processes

tubb5

tubulin, beta 5

tubb5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.642
optic nerve development GO:0021554 15 0.431
brain development GO:0007420 293 0.378
optic nerve morphogenesis GO:0021631 6 0.350
cranial nerve development GO:0021545 42 0.325
nerve development GO:0021675 45 0.254
digestive tract morphogenesis GO:0048546 231 0.225
regulation of protein complex assembly GO:0043254 3 0.195
cranial nerve morphogenesis GO:0021602 15 0.168
neuron differentiation GO:0030182 353 0.165
regulation of cell communication GO:0010646 232 0.165
cytokinesis GO:0000910 3 0.161
cell part morphogenesis GO:0032990 246 0.158
neuron development GO:0048666 262 0.155
cellular component morphogenesis GO:0032989 336 0.151
positive regulation of transport GO:0051050 2 0.150
system process GO:0003008 185 0.147
cell projection organization GO:0030030 284 0.140
signal transduction GO:0007165 455 0.139
exocytosis GO:0006887 1 0.116
positive regulation of exocytosis GO:0045921 1 0.108
positive regulation of secretion by cell GO:1903532 1 0.105
generation of neurons GO:0048699 385 0.105
cell morphogenesis GO:0000902 289 0.102
cell projection morphogenesis GO:0048858 244 0.102
negative regulation of biological process GO:0048519 304 0.101
optic nerve formation GO:0021634 6 0.097
digestive tract development GO:0048565 265 0.096
eye development GO:0001654 277 0.096
regulation of apoptotic process GO:0042981 98 0.091
camera type eye development GO:0043010 222 0.087
fertilization GO:0009566 3 0.085
sensory organ development GO:0007423 393 0.083
sprouting angiogenesis GO:0002040 53 0.083
epithelial cell differentiation GO:0030855 116 0.082
negative regulation of apoptotic process GO:0043066 55 0.077
skeletal muscle organ development GO:0060538 78 0.077
cranial nerve formation GO:0021603 13 0.075
cell surface receptor signaling pathway GO:0007166 325 0.074
regulation of signaling GO:0023051 235 0.074
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.074
negative regulation of cell communication GO:0010648 96 0.072
apoptotic process GO:0006915 116 0.072
positive regulation of secretion GO:0051047 1 0.071
negative regulation of protein complex assembly GO:0031333 1 0.071
regionalization GO:0003002 274 0.070
epithelial cell development GO:0002064 42 0.070
negative regulation of ras protein signal transduction GO:0046580 1 0.069
central nervous system neuron differentiation GO:0021953 74 0.067
hematopoietic or lymphoid organ development GO:0048534 191 0.066
head development GO:0060322 303 0.066
negative regulation of programmed cell death GO:0043069 58 0.065
negative regulation of cellular process GO:0048523 283 0.064
cell cycle g1 s phase transition GO:0044843 1 0.063
digestive system development GO:0055123 289 0.063
regulation of exocytosis GO:0017157 1 0.062
determination of bilateral symmetry GO:0009855 204 0.062
actin filament polymerization GO:0030041 2 0.061
cytoskeleton dependent cytokinesis GO:0061640 3 0.060
hormone transport GO:0009914 2 0.060
aorta development GO:0035904 4 0.060
regulation of establishment of protein localization GO:0070201 4 0.059
programmed cell death GO:0012501 119 0.055
regulation of response to stimulus GO:0048583 269 0.052
dorsal ventral pattern formation GO:0009953 125 0.052
actin polymerization or depolymerization GO:0008154 2 0.052
homeostatic process GO:0042592 142 0.051
axon development GO:0061564 166 0.051
cellular component movement GO:0006928 335 0.049
epiboly GO:0090504 41 0.048
regulation of cellular component movement GO:0051270 55 0.048
regeneration GO:0031099 91 0.047
response to chemical GO:0042221 320 0.047
actin filament based process GO:0030029 64 0.047
ras protein signal transduction GO:0007265 7 0.046
specification of symmetry GO:0009799 204 0.046
regulation of protein polymerization GO:0032271 2 0.046
glucose homeostasis GO:0042593 1 0.045
negative regulation of signal transduction GO:0009968 94 0.045
gastrulation GO:0007369 208 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
protein localization to plasma membrane GO:0072659 1 0.045
aging GO:0007568 2 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.042
stem cell maintenance GO:0019827 4 0.042
growth GO:0040007 174 0.042
regulation of biological quality GO:0065008 263 0.042
regulation of signal transduction GO:0009966 225 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
regulation of gtp catabolic process GO:0033124 2 0.041
cell migration involved in gastrulation GO:0042074 79 0.040
nuclear migration GO:0007097 3 0.040
neuron projection guidance GO:0097485 86 0.040
negative regulation of intracellular protein transport GO:0090317 3 0.040
taxis GO:0042330 109 0.039
small gtpase mediated signal transduction GO:0007264 8 0.039
cartilage development GO:0051216 96 0.039
protein stabilization GO:0050821 2 0.038
membrane fusion GO:0061025 2 0.038
g1 s transition of mitotic cell cycle GO:0000082 1 0.037
immune system process GO:0002376 241 0.037
regulation of localization GO:0032879 104 0.036
protein polymerization GO:0051258 4 0.036
cytokinetic process GO:0032506 2 0.036
larval development GO:0002164 2 0.036
energy reserve metabolic process GO:0006112 2 0.036
organelle organization GO:0006996 227 0.036
Mouse
nucleocytoplasmic transport GO:0006913 4 0.035
signal transduction in absence of ligand GO:0038034 1 0.035
response to organic substance GO:0010033 153 0.034
regulation of calcium ion dependent exocytosis GO:0017158 1 0.034
retina layer formation GO:0010842 24 0.033
axonogenesis GO:0007409 152 0.033
death GO:0016265 121 0.033
spinal cord development GO:0021510 46 0.033
actin filament organization GO:0007015 15 0.033
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.033
embryonic organ development GO:0048568 381 0.033
negative regulation of response to stimulus GO:0048585 104 0.032
cell morphogenesis involved in differentiation GO:0000904 195 0.032
negative regulation of cell death GO:0060548 60 0.032
convergent extension GO:0060026 118 0.032
cell differentiation in spinal cord GO:0021515 40 0.032
actin cytoskeleton organization GO:0030036 63 0.032
neuron projection morphogenesis GO:0048812 161 0.031
cell death GO:0008219 121 0.031
protein acylation GO:0043543 3 0.031
wnt signaling pathway GO:0016055 80 0.030
protein complex biogenesis GO:0070271 30 0.030
Mouse
cellular component disassembly GO:0022411 1 0.030
forebrain development GO:0030900 96 0.030
peptide transport GO:0015833 1 0.030
nucleic acid templated transcription GO:0097659 181 0.029
blood vessel development GO:0001568 246 0.029
mesoderm development GO:0007498 88 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
muscle structure development GO:0061061 196 0.029
germ line stem cell maintenance GO:0030718 2 0.029
chemical homeostasis GO:0048878 49 0.029
intracellular signal transduction GO:0035556 85 0.028
neuron projection development GO:0031175 180 0.028
cardiac cell fate commitment GO:0060911 1 0.028
regulation of microtubule cytoskeleton organization GO:0070507 3 0.028
establishment of localization in cell GO:0051649 77 0.028
protein acetylation GO:0006473 2 0.027
single organism transport GO:0044765 206 0.027
negative regulation of cellular component organization GO:0051129 16 0.027
spinal cord motor neuron differentiation GO:0021522 26 0.027
endoderm development GO:0007492 49 0.027
inner ear receptor cell development GO:0060119 20 0.027
regulation of cell death GO:0010941 103 0.027
protein targeting to membrane GO:0006612 1 0.027
phagocytosis GO:0006909 3 0.026
establishment of localization GO:0051234 244 0.026
segmentation GO:0035282 97 0.026
epithelial cell morphogenesis GO:0003382 2 0.026
tissue regeneration GO:0042246 74 0.026
cellular response to organic substance GO:0071310 105 0.026
gliogenesis GO:0042063 45 0.025
endothelium development GO:0003158 25 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
outflow tract morphogenesis GO:0003151 1 0.025
sympathetic nervous system development GO:0048485 3 0.025
lamellipodium organization GO:0097581 1 0.025
macromolecular complex disassembly GO:0032984 1 0.025
muscle organ development GO:0007517 101 0.025
stem cell division GO:0017145 1 0.024
response to nutrient GO:0007584 3 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
cellular protein complex assembly GO:0043623 19 0.024
reactive oxygen species metabolic process GO:0072593 6 0.024
nuclear transport GO:0051169 4 0.024
retina development in camera type eye GO:0060041 146 0.024
cell proliferation GO:0008283 80 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
homeostasis of number of cells GO:0048872 62 0.023
cellular macromolecular complex assembly GO:0034622 24 0.023
vesicle mediated transport GO:0016192 22 0.023
inner ear receptor cell differentiation GO:0060113 29 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
regulation of hormone secretion GO:0046883 2 0.022
regulation of reactive oxygen species metabolic process GO:2000377 2 0.022
regulation of programmed cell death GO:0043067 101 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
adult behavior GO:0030534 2 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
neuron remodeling GO:0016322 1 0.021
transcription dna templated GO:0006351 181 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
connective tissue development GO:0061448 99 0.021
regulation of cytoskeleton organization GO:0051493 11 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
protein complex disassembly GO:0043241 1 0.021
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.021
positive regulation of protein polymerization GO:0032273 2 0.020
carbohydrate homeostasis GO:0033500 1 0.020
determination of left right symmetry GO:0007368 179 0.020
blood vessel morphogenesis GO:0048514 216 0.020
phagocytosis engulfment GO:0006911 1 0.020
response to monosaccharide GO:0034284 3 0.020
regulation of cell projection assembly GO:0060491 4 0.020
immune system development GO:0002520 191 0.020
regulation of cell motility GO:2000145 46 0.020
nuclear export GO:0051168 1 0.020
cytoskeleton organization GO:0007010 96 0.020
Mouse
regulation of protein transport GO:0051223 3 0.019
neurological system process GO:0050877 62 0.019
cell cycle arrest GO:0007050 1 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
forebrain cell migration GO:0021885 1 0.019
endothelial cell development GO:0001885 12 0.019
angiogenesis GO:0001525 158 0.019
protein complex assembly GO:0006461 30 0.019
Mouse
lamellipodium assembly GO:0030032 1 0.019
aorta morphogenesis GO:0035909 3 0.019
camera type eye morphogenesis GO:0048593 108 0.019
chemosensory behavior GO:0007635 1 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
actin filament based movement GO:0030048 1 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
limb bud formation GO:0060174 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
vasculature development GO:0001944 278 0.018
eye morphogenesis GO:0048592 144 0.018
somite development GO:0061053 96 0.018
regulation of neuron projection development GO:0010975 40 0.018
negative regulation of cell migration GO:0030336 17 0.018
cell migration to the midline involved in heart development GO:0003318 12 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
negative regulation of developmental process GO:0051093 65 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
single organism cellular localization GO:1902580 46 0.018
meiotic cell cycle process GO:1903046 3 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
membrane invagination GO:0010324 1 0.017
post embryonic organ development GO:0048569 4 0.017
wound healing GO:0042060 90 0.017
response to glucose GO:0009749 3 0.017
defense response to fungus GO:0050832 2 0.017
negative regulation of signaling GO:0023057 96 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
gastrulation with mouth forming second GO:0001702 44 0.017
chordate embryonic development GO:0043009 271 0.016
neural retina development GO:0003407 49 0.016
sensory organ morphogenesis GO:0090596 200 0.016
regulation of cell activation GO:0050865 1 0.016
skeletal system development GO:0001501 181 0.016
small molecule metabolic process GO:0044281 77 0.016
hemopoiesis GO:0030097 183 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
amine metabolic process GO:0009308 2 0.016
regulation of wnt signaling pathway GO:0030111 53 0.015
negative regulation of protein transport GO:0051224 3 0.015
atrioventricular valve morphogenesis GO:0003181 6 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
transport GO:0006810 220 0.015
single organism carbohydrate metabolic process GO:0044723 12 0.015
central nervous system projection neuron axonogenesis GO:0021952 15 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.015
regulation of neurogenesis GO:0050767 87 0.015
regulation of anatomical structure size GO:0090066 33 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
protein processing GO:0016485 12 0.015
protein localization to membrane GO:0072657 9 0.015
epidermis development GO:0008544 48 0.014
endothelial cell differentiation GO:0045446 20 0.014
cardiac chamber formation GO:0003207 4 0.014
response to wounding GO:0009611 116 0.014
establishment of nucleus localization GO:0040023 7 0.014
regulation of gtpase activity GO:0043087 2 0.014
neuron projection extension GO:1990138 45 0.014
somatic stem cell maintenance GO:0035019 1 0.014
compound eye development GO:0048749 2 0.014
calcium ion dependent exocytosis GO:0017156 1 0.014
ovulation cycle process GO:0022602 2 0.014
single fertilization GO:0007338 3 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of transport GO:0051049 45 0.014
regulation of cellular response to growth factor stimulus GO:0090287 35 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.014
pronuclear migration GO:0035046 1 0.014
positive regulation of epithelial cell differentiation GO:0030858 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of growth GO:0040008 42 0.014
cellular response to retinoic acid GO:0071300 1 0.014
regulation of fatty acid metabolic process GO:0019217 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
response to hexose GO:0009746 3 0.014
positive regulation of nervous system development GO:0051962 25 0.014
developmental growth GO:0048589 166 0.013
regulation of vesicle mediated transport GO:0060627 9 0.013
cellular component assembly GO:0022607 170 0.013
Mouse
action potential GO:0001508 19 0.013
extracellular matrix organization GO:0030198 27 0.013
cellular amine metabolic process GO:0044106 2 0.013
appendage morphogenesis GO:0035107 56 0.013
regulation of neuron differentiation GO:0045664 56 0.013
ameboidal type cell migration GO:0001667 143 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
hatching GO:0035188 4 0.013
glial cell proliferation GO:0014009 4 0.013
cellular ketone metabolic process GO:0042180 11 0.013
mitotic cytokinesis GO:0000281 3 0.013
anterior posterior pattern specification GO:0009952 152 0.013
positive regulation of signaling GO:0023056 56 0.013
astrocyte differentiation GO:0048708 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
metal ion homeostasis GO:0055065 26 0.013
negative regulation of intracellular transport GO:0032387 3 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
gland development GO:0048732 143 0.012
positive regulation of translation GO:0045727 1 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of protein binding GO:0043393 3 0.012
single organism localization GO:1902578 225 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
nucleic acid metabolic process GO:0090304 244 0.012
cell proliferation in hindbrain GO:0021534 4 0.012
positive regulation of biological process GO:0048518 253 0.012
localization of cell GO:0051674 244 0.012
lipid storage GO:0019915 1 0.012
long chain fatty acid transport GO:0015909 1 0.012
central nervous system neuron development GO:0021954 29 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
establishment of endothelial barrier GO:0061028 3 0.012
maintenance of location GO:0051235 4 0.012
negative regulation of neuron differentiation GO:0045665 10 0.012
positive regulation of apoptotic process GO:0043065 29 0.012
regulation of establishment of planar polarity GO:0090175 4 0.012
fin regeneration GO:0031101 51 0.012
hormone secretion GO:0046879 2 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
gtp metabolic process GO:0046039 4 0.012
ion homeostasis GO:0050801 41 0.012
regulation of developmental process GO:0050793 247 0.012
neural tube development GO:0021915 62 0.012
macromolecule biosynthetic process GO:0009059 227 0.011
regulation of cellular localization GO:0060341 12 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
endothelial cell fate commitment GO:0060839 3 0.011
cell proliferation in forebrain GO:0021846 3 0.011
positive regulation of cell communication GO:0010647 56 0.011
heart development GO:0007507 313 0.011
negative regulation of neuron projection development GO:0010977 9 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
peripheral nervous system neuron development GO:0048935 22 0.011
midbrain development GO:0030901 28 0.011
multicellular organism growth GO:0035264 4 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
positive regulation of signal transduction GO:0009967 56 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
microtubule polymerization GO:0046785 2 0.011
stem cell proliferation GO:0072089 4 0.011
positive regulation of catabolic process GO:0009896 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
regulation of protein targeting GO:1903533 2 0.011
tube morphogenesis GO:0035239 349 0.011
somitogenesis GO:0001756 87 0.011
cell migration involved in heart development GO:0060973 22 0.011
neuroblast proliferation GO:0007405 2 0.010
distal tubule development GO:0072017 1 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
regulation of cell size GO:0008361 29 0.010
venous blood vessel development GO:0060841 9 0.010
endomembrane system organization GO:0010256 13 0.010
mitochondrion organization GO:0007005 4 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
synaptic vesicle transport GO:0048489 1 0.010
smooth muscle contraction GO:0006939 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010

tubb5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.101
lissencephaly DOID:0050453 0 0.090
congenital nervous system abnormality DOID:2490 0 0.090
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.020
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
disease of metabolism DOID:0014667 0 0.010
amyloidosis DOID:9120 0 0.010
acquired metabolic disease DOID:0060158 0 0.010