Danio rerio

0 known processes

sprn2

shadow of prion protein 2

(Aliases: zgc:123052,Sho2,PrP-rel-1,wu:fj12d11,sprnb,MGC123052)

sprn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.061
positive regulation of transport GO:0051050 2 0.052
aging GO:0007568 2 0.048
single organism transport GO:0044765 206 0.046
signal transduction GO:0007165 455 0.043
cell surface receptor signaling pathway GO:0007166 325 0.041
regulation of cytokine production GO:0001817 3 0.039
response to external stimulus GO:0009605 264 0.036
phagocytosis GO:0006909 3 0.036
cellular response to external stimulus GO:0071496 2 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
regulation of multicellular organismal process GO:0051239 277 0.034
protein acetylation GO:0006473 2 0.034
system process GO:0003008 185 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
head development GO:0060322 303 0.032
regulation of biological quality GO:0065008 263 0.031
response to chemical GO:0042221 320 0.031
regulation of metal ion transport GO:0010959 4 0.031
multicellular organism growth GO:0035264 4 0.030
autophagy GO:0006914 4 0.030
response to stress GO:0006950 263 0.030
transport GO:0006810 220 0.030
cellular component morphogenesis GO:0032989 336 0.029
single organism localization GO:1902578 225 0.029
positive regulation of catabolic process GO:0009896 4 0.029
neuron differentiation GO:0030182 353 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
cognition GO:0050890 1 0.029
lipid storage GO:0019915 1 0.028
cell morphogenesis GO:0000902 289 0.028
peptidyl lysine acetylation GO:0018394 2 0.028
protein localization to nucleus GO:0034504 3 0.028
cation transport GO:0006812 81 0.028
establishment of protein localization to organelle GO:0072594 4 0.027
nuclear import GO:0051170 3 0.027
cellular protein catabolic process GO:0044257 4 0.027
regulation of blood pressure GO:0008217 1 0.027
maintenance of location GO:0051235 4 0.027
regulation of tube size GO:0035150 2 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.026
immune system process GO:0002376 241 0.026
g protein coupled receptor signaling pathway GO:0007186 74 0.026
establishment of localization GO:0051234 244 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
eye development GO:0001654 277 0.025
ion transmembrane transport GO:0034220 91 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
nuclear transport GO:0051169 4 0.025
regulation of response to stimulus GO:0048583 269 0.025
generation of neurons GO:0048699 385 0.025
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
heterocycle metabolic process GO:0046483 290 0.024
regulation of blood vessel size GO:0050880 2 0.024
protein acylation GO:0043543 3 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
central nervous system development GO:0007417 387 0.024
response to drug GO:0042493 3 0.024
regulation of protein transport GO:0051223 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
sensory organ development GO:0007423 393 0.024
positive regulation of cell activation GO:0050867 1 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of multicellular organismal development GO:2000026 223 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
positive regulation of cytokine production GO:0001819 2 0.023
immune system development GO:0002520 191 0.023
internal protein amino acid acetylation GO:0006475 2 0.023
protein secretion GO:0009306 1 0.023
amine metabolic process GO:0009308 2 0.023
stem cell proliferation GO:0072089 4 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
positive regulation of secretion GO:0051047 1 0.023
brain development GO:0007420 293 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
transmembrane transport GO:0055085 120 0.023
regulation of autophagy GO:0010506 3 0.023
gene expression GO:0010467 252 0.023
cell part morphogenesis GO:0032990 246 0.023
hemopoiesis GO:0030097 183 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
monovalent inorganic cation transport GO:0015672 42 0.022
cellular response to starvation GO:0009267 1 0.022
glucose homeostasis GO:0042593 1 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
cellular response to nutrient levels GO:0031669 2 0.022
leukocyte proliferation GO:0070661 1 0.022
regulation of developmental process GO:0050793 247 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
specification of symmetry GO:0009799 204 0.022
positive regulation of biological process GO:0048518 253 0.022
neuron development GO:0048666 262 0.022
homeostatic process GO:0042592 142 0.022
regulation of signal transduction GO:0009966 225 0.022
internal peptidyl lysine acetylation GO:0018393 2 0.021
vasculature development GO:0001944 278 0.021
cation transmembrane transport GO:0098655 65 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
regulation of signaling GO:0023051 235 0.021
single organism metabolic process GO:0044710 217 0.021
cellular biosynthetic process GO:0044249 286 0.021
regulation of inflammatory response GO:0050727 2 0.021
protein import GO:0017038 3 0.021
adult behavior GO:0030534 2 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
response to carbohydrate GO:0009743 3 0.021
negative regulation of biological process GO:0048519 304 0.021
cell projection morphogenesis GO:0048858 244 0.021
cell projection organization GO:0030030 284 0.021
blood vessel development GO:0001568 246 0.021
embryonic organ development GO:0048568 381 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
locomotion GO:0040011 313 0.020
cellular amine metabolic process GO:0044106 2 0.020
carbohydrate homeostasis GO:0033500 1 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
ion transport GO:0006811 114 0.020
mononuclear cell proliferation GO:0032943 1 0.020
b cell activation GO:0042113 2 0.020
chemosensory behavior GO:0007635 1 0.020
protein import into nucleus GO:0006606 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
negative regulation of catabolic process GO:0009895 3 0.020
meiotic cell cycle process GO:1903046 3 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
modification dependent protein catabolic process GO:0019941 3 0.019
negative regulation of cellular process GO:0048523 283 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
regulation of cell communication GO:0010646 232 0.019
response to hexose GO:0009746 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
cellular ketone metabolic process GO:0042180 11 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
gtp metabolic process GO:0046039 4 0.019
cellular component biogenesis GO:0044085 178 0.019
cellular component movement GO:0006928 335 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
organic substance biosynthetic process GO:1901576 289 0.019
positive regulation of immune effector process GO:0002699 3 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
gtp catabolic process GO:0006184 2 0.018
single organism nuclear import GO:1902593 3 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
positive regulation of cell cycle GO:0045787 3 0.018
inorganic ion transmembrane transport GO:0098660 57 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
blood circulation GO:0008015 87 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
transcription dna templated GO:0006351 181 0.017
rna metabolic process GO:0016070 219 0.017
chordate embryonic development GO:0043009 271 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
positive regulation of leukocyte mediated immunity GO:0002705 1 0.017
response to monosaccharide GO:0034284 3 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
lymphocyte proliferation GO:0046651 1 0.017
regulation of primary metabolic process GO:0080090 311 0.017
endocrine process GO:0050886 2 0.017
regulation of endocrine process GO:0044060 2 0.017
tube morphogenesis GO:0035239 349 0.017
stem cell maintenance GO:0019827 4 0.017
mitochondrion organization GO:0007005 4 0.017
tissue remodeling GO:0048771 4 0.017
determination of bilateral symmetry GO:0009855 204 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
response to abiotic stimulus GO:0009628 122 0.017
nucleic acid templated transcription GO:0097659 181 0.016
regulation of hormone secretion GO:0046883 2 0.016
inorganic cation transmembrane transport GO:0098662 50 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
biosynthetic process GO:0009058 294 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
regulation of calcium ion transport GO:0051924 2 0.016
neurotransmitter transport GO:0006836 2 0.016
regulation of dendrite development GO:0050773 3 0.016
regulation of protein complex assembly GO:0043254 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of circadian rhythm GO:0042752 4 0.016
protein metabolic process GO:0019538 183 0.016
peptide transport GO:0015833 1 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
female gonad development GO:0008585 4 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
organic acid metabolic process GO:0006082 31 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
lipid catabolic process GO:0016042 4 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
heart development GO:0007507 313 0.015
positive regulation of cellular process GO:0048522 201 0.015
small molecule metabolic process GO:0044281 77 0.015
protein targeting to nucleus GO:0044744 3 0.015
compound eye development GO:0048749 2 0.015
hormone transport GO:0009914 2 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
female sex differentiation GO:0046660 4 0.015
immunoglobulin mediated immune response GO:0016064 3 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
nucleic acid metabolic process GO:0090304 244 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
circulatory system process GO:0003013 87 0.015
rna biosynthetic process GO:0032774 181 0.015
regulation of ph GO:0006885 3 0.015
metal ion transport GO:0030001 58 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
taxis GO:0042330 109 0.015
muscle cell development GO:0055001 115 0.015
neuron projection morphogenesis GO:0048812 161 0.015
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
regulation of cell differentiation GO:0045595 142 0.014
regulation of reproductive process GO:2000241 4 0.014
axonogenesis GO:0007409 152 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
hormone secretion GO:0046879 2 0.014
negative regulation of secretion GO:0051048 2 0.014
regulation of synapse organization GO:0050807 3 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of gene expression GO:0010468 265 0.014
regionalization GO:0003002 274 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
heart process GO:0003015 71 0.014
regulation of metabolic process GO:0019222 359 0.014
regulation of mrna processing GO:0050684 3 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regulation of muscle contraction GO:0006937 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of transporter activity GO:0032409 2 0.013
growth GO:0040007 174 0.013
adherens junction organization GO:0034332 4 0.013
positive regulation of inflammatory response GO:0050729 1 0.013
protein dephosphorylation GO:0006470 3 0.013
response to glucose GO:0009749 3 0.013
response to wounding GO:0009611 116 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
amino acid transport GO:0006865 2 0.013
rna localization GO:0006403 4 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
cell migration GO:0016477 237 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
heart contraction GO:0060047 71 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
peptide metabolic process GO:0006518 1 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
positive regulation of translation GO:0045727 1 0.013
determination of left right symmetry GO:0007368 179 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
neuronal action potential GO:0019228 18 0.013
axon development GO:0061564 166 0.013
negative regulation of cytokine production GO:0001818 1 0.013
cellular component assembly GO:0022607 170 0.013
cytokinesis GO:0000910 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
developmental growth GO:0048589 166 0.013
regulation of cell shape GO:0008360 1 0.013
digestive system development GO:0055123 289 0.013
multicellular organismal signaling GO:0035637 22 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
response to alkaloid GO:0043279 2 0.012
positive regulation of histone modification GO:0031058 1 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
organelle assembly GO:0070925 110 0.012
energy reserve metabolic process GO:0006112 2 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
macroautophagy GO:0016236 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
membrane invagination GO:0010324 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
organism emergence from protective structure GO:0071684 4 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
localization of cell GO:0051674 244 0.012
secondary metabolic process GO:0019748 3 0.012
regulation of binding GO:0051098 3 0.012
protein homooligomerization GO:0051260 3 0.012
neuron projection development GO:0031175 180 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of membrane potential GO:0042391 23 0.012
sequestering of metal ion GO:0051238 3 0.012
cellular component disassembly GO:0022411 1 0.012
multicellular organismal response to stress GO:0033555 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
lipid homeostasis GO:0055088 3 0.012
neurological system process GO:0050877 62 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
macromolecule modification GO:0043412 111 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
spermatid development GO:0007286 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
atp catabolic process GO:0006200 4 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
retina development in camera type eye GO:0060041 146 0.011
meiotic nuclear division GO:0007126 4 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
regulation of wound healing GO:0061041 2 0.011
cell death GO:0008219 121 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
sleep GO:0030431 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
b cell mediated immunity GO:0019724 3 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
b cell differentiation GO:0030183 1 0.011
negative regulation of defense response GO:0031348 2 0.011
actin filament based movement GO:0030048 1 0.011
gas transport GO:0015669 3 0.011
cell motility GO:0048870 244 0.011
mechanosensory behavior GO:0007638 2 0.011
response to uv GO:0009411 3 0.011
small molecule catabolic process GO:0044282 3 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
cellular response to radiation GO:0071478 4 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
cellular protein metabolic process GO:0044267 129 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
somite development GO:0061053 96 0.011
chemotaxis GO:0006935 104 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
activation of mapk activity GO:0000187 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
water transport GO:0006833 15 0.010
regulation of dna recombination GO:0000018 2 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
protein heterooligomerization GO:0051291 1 0.010
cellular response to light stimulus GO:0071482 4 0.010
transmission of nerve impulse GO:0019226 19 0.010
macromolecular complex disassembly GO:0032984 1 0.010
cell substrate adhesion GO:0031589 4 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
nuclear export GO:0051168 1 0.010
regulation of protein polymerization GO:0032271 2 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
response to unfolded protein GO:0006986 2 0.010
regulation of localization GO:0032879 104 0.010
regulation of rna metabolic process GO:0051252 224 0.010
positive regulation of cell killing GO:0031343 2 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
cellular protein modification process GO:0006464 100 0.010
somatic muscle development GO:0007525 4 0.010
digestive tract morphogenesis GO:0048546 231 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
complement activation GO:0006956 3 0.010
photoreceptor cell differentiation GO:0046530 55 0.010
forebrain cell migration GO:0021885 1 0.010
centrosome organization GO:0051297 1 0.010

sprn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.010