Danio rerio

14 known processes

st14a

suppression of tumorigenicity 14 (colon carcinoma) a

(Aliases: zgc:152657,zgc:152656,MGC152657,MGC152656,MGC192760,MGC136950,wu:fl72f01,st14,zgc:136950,wu:fi41g07)

st14a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epidermis development GO:0008544 48 0.551
cell migration GO:0016477 237 0.453
neutrophil migration GO:1990266 10 0.327
cell motility GO:0048870 244 0.307
cellular component movement GO:0006928 335 0.306
skin development GO:0043588 54 0.211
cellular carbohydrate metabolic process GO:0044262 4 0.192
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.164
inner ear development GO:0048839 126 0.150
response to abiotic stimulus GO:0009628 122 0.144
mechanosensory lateral line system development GO:0048881 49 0.142
sensory organ development GO:0007423 393 0.122
cell junction organization GO:0034330 11 0.111
response to oxygen levels GO:0070482 25 0.109
glomerulus development GO:0032835 27 0.106
myeloid leukocyte migration GO:0097529 12 0.105
embryonic viscerocranium morphogenesis GO:0048703 52 0.098
positive regulation of transport GO:0051050 2 0.094
hematopoietic stem cell differentiation GO:0060218 20 0.093
regulation of dna templated transcription in response to stress GO:0043620 0 0.091
leukocyte chemotaxis GO:0030595 12 0.090
regulation of nitrogen compound metabolic process GO:0051171 251 0.089
response to external stimulus GO:0009605 264 0.084
response to mechanical stimulus GO:0009612 24 0.083
actin polymerization or depolymerization GO:0008154 2 0.083
cellular amino acid metabolic process GO:0006520 7 0.080
neutrophil chemotaxis GO:0030593 10 0.078
alcohol biosynthetic process GO:0046165 2 0.078
regulation of cellular component movement GO:0051270 55 0.077
cellular modified amino acid metabolic process GO:0006575 3 0.077
locomotion GO:0040011 313 0.076
stem cell maintenance GO:0019827 4 0.075
immune system process GO:0002376 241 0.074
epidermal cell differentiation GO:0009913 36 0.074
embryonic organ development GO:0048568 381 0.073
adherens junction organization GO:0034332 4 0.073
cellular response to chemical stimulus GO:0070887 157 0.072
granulocyte migration GO:0097530 11 0.069
urogenital system development GO:0001655 97 0.067
extracellular structure organization GO:0043062 27 0.066
regulation of mrna processing GO:0050684 3 0.065
kidney development GO:0001822 92 0.063
autophagy GO:0006914 4 0.063
head development GO:0060322 303 0.062
rna metabolic process GO:0016070 219 0.061
epithelial cell morphogenesis GO:0003382 2 0.061
lateral line system development GO:0048925 76 0.060
organic acid metabolic process GO:0006082 31 0.057
cell chemotaxis GO:0060326 17 0.056
regulation of carbohydrate metabolic process GO:0006109 4 0.056
chordate embryonic development GO:0043009 271 0.056
granulocyte chemotaxis GO:0071621 11 0.055
regulation of cell shape GO:0008360 1 0.053
leukocyte migration GO:0050900 15 0.052
cell projection organization GO:0030030 284 0.051
cell projection morphogenesis GO:0048858 244 0.051
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.051
regulation of lipase activity GO:0060191 2 0.050
regulation of cell migration GO:0030334 40 0.050
hematopoietic progenitor cell differentiation GO:0002244 23 0.047
positive regulation of cytoskeleton organization GO:0051495 3 0.047
extracellular matrix organization GO:0030198 27 0.046
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.046
monoamine transport GO:0015844 1 0.045
positive regulation of macromolecule metabolic process GO:0010604 93 0.045
response to amino acid GO:0043200 2 0.045
regulation of biological quality GO:0065008 263 0.043
aging GO:0007568 2 0.043
detection of stimulus GO:0051606 29 0.042
vasculature development GO:0001944 278 0.042
positive regulation of secretion by cell GO:1903532 1 0.040
cell cell junction organization GO:0045216 10 0.040
protein dephosphorylation GO:0006470 3 0.040
regulation of phospholipase c activity GO:1900274 1 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
polyol metabolic process GO:0019751 1 0.039
positive regulation of cellular process GO:0048522 201 0.039
immune system development GO:0002520 191 0.039
protein polymerization GO:0051258 4 0.039
establishment of epithelial cell polarity GO:0090162 2 0.038
cellular component biogenesis GO:0044085 178 0.038
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.038
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.037
positive regulation of cellular component biogenesis GO:0044089 3 0.037
inositol phosphate metabolic process GO:0043647 1 0.037
response to inorganic substance GO:0010035 38 0.037
hair cell differentiation GO:0035315 32 0.036
actin filament based movement GO:0030048 1 0.036
regulation of ion transmembrane transporter activity GO:0032412 2 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
cellular component assembly GO:0022607 170 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.034
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.034
regulation of biosynthetic process GO:0009889 250 0.034
neuroblast proliferation GO:0007405 2 0.034
protein polyubiquitination GO:0000209 4 0.034
alpha amino acid metabolic process GO:1901605 3 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
regulation of vasculature development GO:1901342 33 0.033
ear development GO:0043583 127 0.033
protein k48 linked ubiquitination GO:0070936 1 0.033
cellular amine metabolic process GO:0044106 2 0.033
actin filament polymerization GO:0030041 2 0.032
regulation of carbohydrate biosynthetic process GO:0043255 1 0.032
chemotaxis GO:0006935 104 0.032
defense response to other organism GO:0098542 33 0.032
morphogenesis of an epithelium GO:0002009 333 0.032
single organism transport GO:0044765 206 0.032
nephron development GO:0072006 31 0.032
myotube differentiation GO:0014902 45 0.032
cellular pigmentation GO:0033059 30 0.031
heart contraction GO:0060047 71 0.031
hemopoiesis GO:0030097 183 0.031
regulation of gene expression GO:0010468 265 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.030
epithelial cell differentiation GO:0030855 116 0.030
blood vessel morphogenesis GO:0048514 216 0.030
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.030
embryonic skeletal system development GO:0048706 97 0.030
regulation of blood pressure GO:0008217 1 0.029
response to acid chemical GO:0001101 17 0.029
regulation of cell motility GO:2000145 46 0.029
protein complex disassembly GO:0043241 1 0.029
amine metabolic process GO:0009308 2 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
renal system development GO:0072001 94 0.029
heart process GO:0003015 71 0.028
cell morphogenesis GO:0000902 289 0.028
carbohydrate biosynthetic process GO:0016051 1 0.028
calcium ion homeostasis GO:0055074 19 0.028
negative regulation of defense response GO:0031348 2 0.028
regulation of blood circulation GO:1903522 32 0.028
regulation of protein complex assembly GO:0043254 3 0.028
regulation of protein targeting GO:1903533 2 0.028
striated muscle cell differentiation GO:0051146 129 0.028
medulla oblongata development GO:0021550 4 0.028
blood circulation GO:0008015 87 0.027
negative regulation of stem cell differentiation GO:2000737 2 0.027
establishment of localization GO:0051234 244 0.027
nucleic acid metabolic process GO:0090304 244 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
eye development GO:0001654 277 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
biosynthetic process GO:0009058 294 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
small molecule metabolic process GO:0044281 77 0.026
muscle cell differentiation GO:0042692 139 0.026
cilium morphogenesis GO:0060271 85 0.026
growth GO:0040007 174 0.026
glomerular epithelium development GO:0072010 12 0.026
nucleic acid templated transcription GO:0097659 181 0.025
vasculogenesis GO:0001570 41 0.025
regulation of synapse organization GO:0050807 3 0.025
regulation of primary metabolic process GO:0080090 311 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
protein localization to nucleus GO:0034504 3 0.025
response to chemical GO:0042221 320 0.025
single organism metabolic process GO:0044710 217 0.025
detection of abiotic stimulus GO:0009582 24 0.024
positive regulation of cellular biosynthetic process GO:0031328 68 0.024
cytokinesis GO:0000910 3 0.024
embryonic cranial skeleton morphogenesis GO:0048701 90 0.024
apical junction assembly GO:0043297 1 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
single organismal cell cell adhesion GO:0016337 29 0.024
brain development GO:0007420 293 0.024
stem cell division GO:0017145 1 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
s adenosylmethionine metabolic process GO:0046500 1 0.023
response to wounding GO:0009611 116 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
positive regulation of secretion GO:0051047 1 0.023
response to stress GO:0006950 263 0.023
regulation of filopodium assembly GO:0051489 2 0.023
cellular response to oxygen levels GO:0071453 1 0.023
blood vessel development GO:0001568 246 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
proteasomal protein catabolic process GO:0010498 2 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
inner ear receptor cell differentiation GO:0060113 29 0.022
regulation of protein complex disassembly GO:0043244 1 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
gene expression GO:0010467 252 0.022
regulation of cytokine production GO:0001817 3 0.022
glomerular filtration GO:0003094 6 0.022
protein depolymerization GO:0051261 1 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.021
retina development in camera type eye GO:0060041 146 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
syncytium formation GO:0006949 12 0.021
embryonic heart tube development GO:0035050 133 0.021
cellular response to starvation GO:0009267 1 0.021
desmosome assembly GO:0002159 2 0.021
macromolecular complex disassembly GO:0032984 1 0.021
cellular localization GO:0051641 97 0.021
protein localization to plasma membrane GO:0072659 1 0.021
cellular response to nutrient levels GO:0031669 2 0.021
adult behavior GO:0030534 2 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
positive regulation of biological process GO:0048518 253 0.021
transcription dna templated GO:0006351 181 0.021
regulation of signal transduction GO:0009966 225 0.020
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.020
detection of mechanical stimulus GO:0050982 11 0.020
meiotic nuclear division GO:0007126 4 0.020
regulation of response to external stimulus GO:0032101 31 0.020
single organism membrane organization GO:0044802 20 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
angiogenesis GO:0001525 158 0.020
renal filtration GO:0097205 10 0.020
regulation of metabolic process GO:0019222 359 0.020
skeletal system development GO:0001501 181 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
organic substance biosynthetic process GO:1901576 289 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
cell part morphogenesis GO:0032990 246 0.019
cellular component disassembly GO:0022411 1 0.019
angioblast cell migration GO:0035476 9 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
negative regulation of cell communication GO:0010648 96 0.018
positive regulation of defense response to virus by host GO:0002230 0 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
actin cytoskeleton organization GO:0030036 63 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
stem cell proliferation GO:0072089 4 0.018
actin filament based process GO:0030029 64 0.018
cartilage morphogenesis GO:0060536 13 0.018
rna 3 end processing GO:0031123 2 0.018
granulocyte differentiation GO:0030851 8 0.018
regulation of transcription dna templated GO:0006355 213 0.018
cell cell junction maintenance GO:0045217 1 0.017
heterocycle metabolic process GO:0046483 290 0.017
regulation of circadian rhythm GO:0042752 4 0.017
syncytium formation by plasma membrane fusion GO:0000768 12 0.017
mechanoreceptor differentiation GO:0042490 37 0.017
cellular component maintenance GO:0043954 3 0.017
nuclear transport GO:0051169 4 0.017
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.017
response to metal ion GO:0010038 34 0.017
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.016
detection of stimulus involved in sensory perception GO:0050906 21 0.016
epithelial cell differentiation involved in kidney development GO:0035850 13 0.016
sensory system development GO:0048880 76 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
tight junction assembly GO:0070830 1 0.015
regulation of transporter activity GO:0032409 2 0.015
regulation of protein depolymerization GO:1901879 1 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of mrna catabolic process GO:0061013 3 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
regulation of synapse assembly GO:0051963 3 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
positive regulation of metabolic process GO:0009893 108 0.015
regulation of rna metabolic process GO:0051252 224 0.015
cellular ketone metabolic process GO:0042180 11 0.015
gland development GO:0048732 143 0.015
protein secretion GO:0009306 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
cardiac cell fate commitment GO:0060911 1 0.014
detection of external stimulus GO:0009581 24 0.014
ion transmembrane transport GO:0034220 91 0.014
dna templated transcription elongation GO:0006354 3 0.014
cardiac conduction system development GO:0003161 1 0.014
cofactor metabolic process GO:0051186 15 0.014
regulation of cell death GO:0010941 103 0.014
metal ion homeostasis GO:0055065 26 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
positive regulation of glucose transport GO:0010828 1 0.014
regulation of heart contraction GO:0008016 32 0.014
stem cell differentiation GO:0048863 117 0.014
protein import into nucleus GO:0006606 3 0.014
nuclear migration GO:0007097 3 0.014
glomerulus vasculature development GO:0072012 2 0.014
actin filament organization GO:0007015 15 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
system process GO:0003008 185 0.014
digestive tract development GO:0048565 265 0.013
cellular response to radiation GO:0071478 4 0.013
t cell differentiation in thymus GO:0033077 6 0.013
zymogen activation GO:0031638 3 0.013
regulation of developmental process GO:0050793 247 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
posterior lateral line system development GO:0048915 46 0.013
regulation of sodium ion transport GO:0002028 2 0.013
glucose import GO:0046323 2 0.013
single organism organelle organization GO:1902589 199 0.013
muscle organ development GO:0007517 101 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
signal transduction GO:0007165 455 0.013
response to organonitrogen compound GO:0010243 12 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
mononuclear cell proliferation GO:0032943 1 0.013
sensory perception of mechanical stimulus GO:0050954 16 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of system process GO:0044057 40 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
rna biosynthetic process GO:0032774 181 0.013
cellular protein catabolic process GO:0044257 4 0.012
cellular response to external stimulus GO:0071496 2 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
skeletal system morphogenesis GO:0048705 102 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
protein modification process GO:0036211 100 0.012
hepaticobiliary system development GO:0061008 98 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
response to uv GO:0009411 3 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
melanosome localization GO:0032400 21 0.012
small molecule catabolic process GO:0044282 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
multi organism cellular process GO:0044764 2 0.012
positive regulation of cell death GO:0010942 29 0.012
larval development GO:0002164 2 0.012
cellular response to hypoxia GO:0071456 1 0.012
regulation of locomotion GO:0040012 55 0.012
regulation of wound healing GO:0061041 2 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
macroautophagy GO:0016236 1 0.012
connective tissue development GO:0061448 99 0.012
regulation of glucose transport GO:0010827 1 0.012
cell substrate adhesion GO:0031589 4 0.012
negative regulation of cellular process GO:0048523 283 0.012
establishment of pigment granule localization GO:0051905 22 0.012
response to decreased oxygen levels GO:0036293 25 0.012
organic cyclic compound metabolic process GO:1901360 301 0.011
lymphocyte proliferation GO:0046651 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
intracellular signal transduction GO:0035556 85 0.011
liver development GO:0001889 96 0.011
central nervous system neuron development GO:0021954 29 0.011
central nervous system development GO:0007417 387 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regulation of phospholipase activity GO:0010517 2 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
protein import GO:0017038 3 0.011
protein homooligomerization GO:0051260 3 0.011
wound healing GO:0042060 90 0.011
regulation of cell communication GO:0010646 232 0.011
cognition GO:0050890 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of peptidase activity GO:0052547 23 0.011
cellular protein complex disassembly GO:0043624 1 0.011
sodium ion transport GO:0006814 24 0.011
single organism membrane fusion GO:0044801 2 0.011
determination of dorsal ventral asymmetry GO:0048262 34 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
digestive tract morphogenesis GO:0048546 231 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
cartilage development GO:0051216 96 0.011
macromolecule modification GO:0043412 111 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
striated muscle tissue development GO:0014706 110 0.011
maintenance of location GO:0051235 4 0.010
protein metabolic process GO:0019538 183 0.010
cellular response to stress GO:0033554 62 0.010
regulation of organ growth GO:0046620 3 0.010
keratinocyte differentiation GO:0030216 0 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.010
kidney epithelium development GO:0072073 23 0.010
single organism nuclear import GO:1902593 3 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
generation of neurons GO:0048699 385 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
tissue regeneration GO:0042246 74 0.010
response to organic substance GO:0010033 153 0.010

st14a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
reproductive organ cancer DOID:193 0 0.021
female reproductive organ cancer DOID:120 0 0.021
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
heart disease DOID:114 0 0.017
cardiomyopathy DOID:0050700 0 0.017
cardiovascular system disease DOID:1287 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017
disease of metabolism DOID:0014667 0 0.016
amyloidosis DOID:9120 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
breast cancer DOID:1612 0 0.010
thoracic cancer DOID:5093 0 0.010