Danio rerio

0 known processes

dbx2

developing brain homeobox 2

(Aliases: hlx3,zgc:110519)

dbx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biosynthetic process GO:0009058 294 0.093
signal transduction GO:0007165 455 0.085
macromolecule biosynthetic process GO:0009059 227 0.082
regulation of macromolecule metabolic process GO:0060255 317 0.079
nitrogen compound metabolic process GO:0006807 319 0.066
cellular macromolecule metabolic process GO:0044260 391 0.066
aromatic compound biosynthetic process GO:0019438 217 0.066
cellular biosynthetic process GO:0044249 286 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.062
regulation of nitrogen compound metabolic process GO:0051171 251 0.062
cell surface receptor signaling pathway GO:0007166 325 0.062
regionalization GO:0003002 274 0.060
neuron differentiation GO:0030182 353 0.058
regulation of metabolic process GO:0019222 359 0.057
stem cell maintenance GO:0019827 4 0.057
organic cyclic compound metabolic process GO:1901360 301 0.055
positive regulation of transport GO:0051050 2 0.054
regulation of rna biosynthetic process GO:2001141 213 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
heterocycle metabolic process GO:0046483 290 0.052
transcription dna templated GO:0006351 181 0.052
cellular aromatic compound metabolic process GO:0006725 295 0.051
nucleobase containing compound metabolic process GO:0006139 274 0.048
aging GO:0007568 2 0.048
cellular macromolecule biosynthetic process GO:0034645 224 0.048
nucleic acid templated transcription GO:0097659 181 0.047
cellular component morphogenesis GO:0032989 336 0.047
rna metabolic process GO:0016070 219 0.046
organic substance biosynthetic process GO:1901576 289 0.045
positive regulation of biological process GO:0048518 253 0.045
heterocycle biosynthetic process GO:0018130 215 0.045
nucleic acid metabolic process GO:0090304 244 0.045
central nervous system development GO:0007417 387 0.044
tube morphogenesis GO:0035239 349 0.044
regulation of multicellular organismal process GO:0051239 277 0.043
regulation of developmental process GO:0050793 247 0.042
generation of neurons GO:0048699 385 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.041
regulation of cytokine production GO:0001817 3 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.041
cellular component movement GO:0006928 335 0.041
regulation of rna metabolic process GO:0051252 224 0.039
larval development GO:0002164 2 0.038
morphogenesis of an epithelium GO:0002009 333 0.038
locomotion GO:0040011 313 0.038
rna biosynthetic process GO:0032774 181 0.038
negative regulation of signal transduction GO:0009968 94 0.038
cell morphogenesis involved in differentiation GO:0000904 195 0.038
regulation of nucleic acid templated transcription GO:1903506 213 0.037
regulation of cell communication GO:0010646 232 0.037
regulation of multicellular organism growth GO:0040014 4 0.036
regulation of gene expression GO:0010468 265 0.035
muscle organ development GO:0007517 101 0.035
multicellular organism growth GO:0035264 4 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
regulation of synapse assembly GO:0051963 3 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
cell part morphogenesis GO:0032990 246 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
negative regulation of cellular process GO:0048523 283 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
digestive system development GO:0055123 289 0.033
nucleocytoplasmic transport GO:0006913 4 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
regulation of transcription dna templated GO:0006355 213 0.032
cellular response to external stimulus GO:0071496 2 0.031
regulation of biosynthetic process GO:0009889 250 0.031
cell projection organization GO:0030030 284 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
brain development GO:0007420 293 0.030
regulation of stem cell differentiation GO:2000736 4 0.029
cell morphogenesis GO:0000902 289 0.029
protein import GO:0017038 3 0.029
maintenance of location GO:0051235 4 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
gastrulation GO:0007369 208 0.029
gene expression GO:0010467 252 0.029
nuclear transport GO:0051169 4 0.028
localization of cell GO:0051674 244 0.028
neuron projection morphogenesis GO:0048812 161 0.028
regulation of protein transport GO:0051223 3 0.028
embryonic organ morphogenesis GO:0048562 274 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
negative regulation of biological process GO:0048519 304 0.027
cellular amine metabolic process GO:0044106 2 0.027
cell projection morphogenesis GO:0048858 244 0.027
protein secretion GO:0009306 1 0.027
developmental growth GO:0048589 166 0.027
regulation of primary metabolic process GO:0080090 311 0.027
embryonic organ development GO:0048568 381 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
amine metabolic process GO:0009308 2 0.025
regulation of synapse organization GO:0050807 3 0.025
protein targeting to nucleus GO:0044744 3 0.025
lipid storage GO:0019915 1 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
regulation of binding GO:0051098 3 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
small molecule metabolic process GO:0044281 77 0.024
dorsal ventral pattern formation GO:0009953 125 0.024
response to external stimulus GO:0009605 264 0.024
growth GO:0040007 174 0.024
regulation of signal transduction GO:0009966 225 0.024
digestive tract morphogenesis GO:0048546 231 0.023
protein localization to nucleus GO:0034504 3 0.023
sensory organ development GO:0007423 393 0.023
regulation of response to stimulus GO:0048583 269 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
regulation of protein targeting GO:1903533 2 0.023
muscle structure development GO:0061061 196 0.022
establishment of localization GO:0051234 244 0.022
wnt signaling pathway GO:0016055 80 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
single organism metabolic process GO:0044710 217 0.022
organelle organization GO:0006996 227 0.022
stem cell proliferation GO:0072089 4 0.022
nuclear import GO:0051170 3 0.022
single organism nuclear import GO:1902593 3 0.022
stem cell differentiation GO:0048863 117 0.022
axon development GO:0061564 166 0.022
positive regulation of cellular process GO:0048522 201 0.022
neuron projection development GO:0031175 180 0.021
membrane fusion GO:0061025 2 0.021
regulation of signaling GO:0023051 235 0.021
negative regulation of cell communication GO:0010648 96 0.021
mesenchyme development GO:0060485 127 0.021
cell motility GO:0048870 244 0.021
negative regulation of signaling GO:0023057 96 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
development of primary female sexual characteristics GO:0046545 4 0.020
regulation of protein complex assembly GO:0043254 3 0.020
spinal cord development GO:0021510 46 0.020
cellular ketone metabolic process GO:0042180 11 0.020
single organism membrane fusion GO:0044801 2 0.020
determination of bilateral symmetry GO:0009855 204 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
regulation of cell shape GO:0008360 1 0.020
cellular component disassembly GO:0022411 1 0.020
gtp metabolic process GO:0046039 4 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of organ growth GO:0046620 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
cellular protein catabolic process GO:0044257 4 0.019
organic acid metabolic process GO:0006082 31 0.019
protein import into nucleus GO:0006606 3 0.019
response to chemical GO:0042221 320 0.019
gtp catabolic process GO:0006184 2 0.019
eye development GO:0001654 277 0.019
female gonad development GO:0008585 4 0.019
renal tubule morphogenesis GO:0061333 1 0.019
mitochondrion organization GO:0007005 4 0.019
negative regulation of protein transport GO:0051224 3 0.019
anterior posterior pattern specification GO:0009952 152 0.019
specification of symmetry GO:0009799 204 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
synaptic target recognition GO:0008039 1 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.019
axonogenesis GO:0007409 152 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
amino acid transport GO:0006865 2 0.018
head development GO:0060322 303 0.018
system process GO:0003008 185 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
multi organism process GO:0051704 134 0.018
positive regulation of secretion GO:0051047 1 0.018
compound eye development GO:0048749 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of reproductive process GO:2000241 4 0.018
response to drug GO:0042493 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
camera type eye development GO:0043010 222 0.017
germ line stem cell maintenance GO:0030718 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
muscle cell differentiation GO:0042692 139 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
intracellular signal transduction GO:0035556 85 0.017
neuron development GO:0048666 262 0.017
cellular protein metabolic process GO:0044267 129 0.017
female sex differentiation GO:0046660 4 0.017
chordate embryonic development GO:0043009 271 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
positive regulation of cell cycle GO:0045787 3 0.016
cell fate specification GO:0001708 68 0.016
protein metabolic process GO:0019538 183 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
sensory organ morphogenesis GO:0090596 200 0.016
blood vessel development GO:0001568 246 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
stem cell development GO:0048864 82 0.016
response to monosaccharide GO:0034284 3 0.015
segmentation GO:0035282 97 0.015
somatic stem cell maintenance GO:0035019 1 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of protein binding GO:0043393 3 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
regulation of biological quality GO:0065008 263 0.015
somatic muscle development GO:0007525 4 0.015
cell migration GO:0016477 237 0.015
negative regulation of metabolic process GO:0009892 86 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
tissue remodeling GO:0048771 4 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
response to stress GO:0006950 263 0.015
peptide transport GO:0015833 1 0.014
response to biotic stimulus GO:0009607 97 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of nervous system development GO:0051960 90 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
death GO:0016265 121 0.014
transport GO:0006810 220 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
positive regulation of cytokine production GO:0001819 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
mesoderm development GO:0007498 88 0.014
b cell activation GO:0042113 2 0.014
somite development GO:0061053 96 0.014
cellular response to nutrient levels GO:0031669 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
single organism organelle organization GO:1902589 199 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
regulation of autophagy GO:0010506 3 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
regulation of organelle assembly GO:1902115 4 0.014
positive regulation of catabolic process GO:0009896 4 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
somitogenesis GO:0001756 87 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
oxoacid metabolic process GO:0043436 31 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of cell activation GO:0050865 1 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of tube size GO:0035150 2 0.013
digestive tract development GO:0048565 265 0.013
forebrain development GO:0030900 96 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of cell projection assembly GO:0060491 4 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
cell death GO:0008219 121 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of mrna processing GO:0050684 3 0.013
positive regulation of immune effector process GO:0002699 3 0.013
autophagy GO:0006914 4 0.013
heart development GO:0007507 313 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
adult behavior GO:0030534 2 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
organelle fusion GO:0048284 3 0.013
ear development GO:0043583 127 0.013
vasculature development GO:0001944 278 0.013
exocytosis GO:0006887 1 0.013
response to nutrient GO:0007584 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
blood vessel morphogenesis GO:0048514 216 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
positive regulation of metabolic process GO:0009893 108 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
cellular component assembly GO:0022607 170 0.012
response to carbohydrate GO:0009743 3 0.012
apoptotic process GO:0006915 116 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
response to other organism GO:0051707 97 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
response to external biotic stimulus GO:0043207 97 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
macromolecular complex disassembly GO:0032984 1 0.012
protein depolymerization GO:0051261 1 0.012
regulation of localization GO:0032879 104 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
regulation of cell death GO:0010941 103 0.012
kidney development GO:0001822 92 0.012
cell fate commitment GO:0045165 99 0.012
inner ear development GO:0048839 126 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
positive regulation of gene expression GO:0010628 71 0.012
astrocyte differentiation GO:0048708 1 0.012
protein complex disassembly GO:0043241 1 0.012
determination of left right symmetry GO:0007368 179 0.012
regulation of cell differentiation GO:0045595 142 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
phagocytosis GO:0006909 3 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
cellular component biogenesis GO:0044085 178 0.012
cell substrate junction assembly GO:0007044 2 0.012
meiotic nuclear division GO:0007126 4 0.012
macroautophagy GO:0016236 1 0.012
gland development GO:0048732 143 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
leukocyte proliferation GO:0070661 1 0.011
regeneration GO:0031099 91 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
protein acetylation GO:0006473 2 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
organelle assembly GO:0070925 110 0.011
positive regulation of blood circulation GO:1903524 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
oocyte maturation GO:0001556 4 0.011
chemotaxis GO:0006935 104 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
programmed cell death GO:0012501 119 0.011
glucose homeostasis GO:0042593 1 0.011
single organism localization GO:1902578 225 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
neuroblast proliferation GO:0007405 2 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
response to hexose GO:0009746 3 0.011
cell substrate adhesion GO:0031589 4 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
chemosensory behavior GO:0007635 1 0.011
diencephalon development GO:0021536 58 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of exocytosis GO:0017157 1 0.011
primary neural tube formation GO:0014020 1 0.011
protein homooligomerization GO:0051260 3 0.011
urogenital system development GO:0001655 97 0.011
muscle tissue development GO:0060537 110 0.011
regulation of transport GO:0051049 45 0.011
regulation of protein complex disassembly GO:0043244 1 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
homeostatic process GO:0042592 142 0.010
bmp signaling pathway GO:0030509 52 0.010
cellular protein modification process GO:0006464 100 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
phagocytosis engulfment GO:0006911 1 0.010
regulation of metal ion transport GO:0010959 4 0.010
rhombomere 5 development GO:0021571 4 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
stem cell division GO:0017145 1 0.010
skeletal system development GO:0001501 181 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
macromolecule modification GO:0043412 111 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
meiotic cell cycle process GO:1903046 3 0.010
neurotransmitter transport GO:0006836 2 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
immune system development GO:0002520 191 0.010
protein acylation GO:0043543 3 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
cognition GO:0050890 1 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010

dbx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.013
musculoskeletal system disease DOID:17 0 0.010