Danio rerio

0 known processes

spc24

SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)

(Aliases: zgc:110417,wu:fb79a02)

spc24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound metabolic process GO:1901360 301 0.220
cell cycle GO:0007049 93 0.140
response to chemical GO:0042221 320 0.132
negative regulation of biological process GO:0048519 304 0.126
positive regulation of dna metabolic process GO:0051054 1 0.117
cell death GO:0008219 121 0.114
regulation of response to stimulus GO:0048583 269 0.101
response to stress GO:0006950 263 0.101
regulation of circadian rhythm GO:0042752 4 0.096
signal transduction by p53 class mediator GO:0072331 13 0.094
double strand break repair via homologous recombination GO:0000724 1 0.094
small molecule metabolic process GO:0044281 77 0.092
double strand break repair GO:0006302 3 0.092
negative regulation of cellular process GO:0048523 283 0.089
larval development GO:0002164 2 0.085
regulation of multicellular organismal development GO:2000026 223 0.085
aging GO:0007568 2 0.082
organelle organization GO:0006996 227 0.078
organic acid metabolic process GO:0006082 31 0.077
biosynthetic process GO:0009058 294 0.077
cellular nitrogen compound metabolic process GO:0034641 290 0.076
cellular macromolecule metabolic process GO:0044260 391 0.074
transcription dna templated GO:0006351 181 0.074
meiotic nuclear division GO:0007126 4 0.073
cellular biosynthetic process GO:0044249 286 0.070
positive regulation of cellular process GO:0048522 201 0.063
organic substance biosynthetic process GO:1901576 289 0.062
regulation of dna recombination GO:0000018 2 0.061
nitrogen compound metabolic process GO:0006807 319 0.059
positive regulation of cellular catabolic process GO:0031331 3 0.058
signal transduction GO:0007165 455 0.057
single organism metabolic process GO:0044710 217 0.057
regulation of metabolic process GO:0019222 359 0.057
regulation of primary metabolic process GO:0080090 311 0.056
apoptotic process GO:0006915 116 0.054
recombinational repair GO:0000725 1 0.054
gene expression GO:0010467 252 0.053
nucleobase containing compound metabolic process GO:0006139 274 0.052
regulation of gene expression GO:0010468 265 0.052
cellular component biogenesis GO:0044085 178 0.052
nucleic acid metabolic process GO:0090304 244 0.050
positive regulation of cell cycle GO:0045787 3 0.049
oxoacid metabolic process GO:0043436 31 0.049
heterocycle metabolic process GO:0046483 290 0.048
regulation of reactive oxygen species metabolic process GO:2000377 2 0.046
peptidyl lysine dimethylation GO:0018027 1 0.046
meiotic chromosome segregation GO:0045132 3 0.045
histone h3 k4 methylation GO:0051568 2 0.045
amine metabolic process GO:0009308 2 0.044
central nervous system development GO:0007417 387 0.044
regulation of apoptotic process GO:0042981 98 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.044
regulation of developmental process GO:0050793 247 0.043
single organism organelle organization GO:1902589 199 0.043
mitotic cell cycle embryonic GO:0045448 2 0.043
negative regulation of mapk cascade GO:0043409 4 0.043
morphogenesis of an epithelium GO:0002009 333 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
positive regulation of catabolic process GO:0009896 4 0.042
response to organic substance GO:0010033 153 0.042
carboxylic acid metabolic process GO:0019752 22 0.041
g2 m transition of mitotic cell cycle GO:0000086 4 0.041
cellular ketone metabolic process GO:0042180 11 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
regulation of protein complex assembly GO:0043254 3 0.040
head development GO:0060322 303 0.040
cellular component assembly GO:0022607 170 0.040
intracellular signal transduction GO:0035556 85 0.039
regulation of multicellular organismal process GO:0051239 277 0.038
regulation of cellular amine metabolic process GO:0033238 0 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
sensory organ development GO:0007423 393 0.037
cellular response to chemical stimulus GO:0070887 157 0.036
purine nucleoside monophosphate catabolic process GO:0009128 4 0.036
regulation of biological quality GO:0065008 263 0.036
mitotic cell cycle process GO:1903047 48 0.035
positive regulation of histone modification GO:0031058 1 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.035
neuron differentiation GO:0030182 353 0.034
regulation of signaling GO:0023051 235 0.034
digestive system development GO:0055123 289 0.034
protein acetylation GO:0006473 2 0.034
sensory organ morphogenesis GO:0090596 200 0.033
response to alkaloid GO:0043279 2 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
regulation of chromosome segregation GO:0051983 1 0.032
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
cell cycle arrest GO:0007050 1 0.031
cellular response to decreased oxygen levels GO:0036294 1 0.031
cell migration GO:0016477 237 0.031
cellular component movement GO:0006928 335 0.031
positive regulation of developmental process GO:0051094 50 0.031
maintenance of location GO:0051235 4 0.030
response to endogenous stimulus GO:0009719 83 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
response to drug GO:0042493 3 0.030
protein metabolic process GO:0019538 183 0.030
heart development GO:0007507 313 0.029
cell cycle g2 m phase transition GO:0044839 4 0.029
centrosome cycle GO:0007098 1 0.029
cellular response to oxygen levels GO:0071453 1 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
single organism localization GO:1902578 225 0.028
rna localization GO:0006403 4 0.028
cellular localization GO:0051641 97 0.027
programmed cell death GO:0012501 119 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
meiosis i GO:0007127 1 0.027
immune system development GO:0002520 191 0.027
single organism nuclear import GO:1902593 3 0.027
dna metabolic process GO:0006259 27 0.027
positive regulation of biological process GO:0048518 253 0.026
positive regulation of chromatin modification GO:1903310 1 0.026
blood vessel morphogenesis GO:0048514 216 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
macromolecule modification GO:0043412 111 0.026
heterocycle biosynthetic process GO:0018130 215 0.025
microtubule organizing center organization GO:0031023 1 0.025
cell projection organization GO:0030030 284 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
atp catabolic process GO:0006200 4 0.025
rna metabolic process GO:0016070 219 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
nuclear transport GO:0051169 4 0.024
negative regulation of developmental process GO:0051093 65 0.024
centrosome organization GO:0051297 1 0.024
negative regulation of nuclear division GO:0051784 3 0.024
regulation of protein transport GO:0051223 3 0.024
multicellular organism growth GO:0035264 4 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
regulation of cell communication GO:0010646 232 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
meiotic cell cycle process GO:1903046 3 0.023
vasculature development GO:0001944 278 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
protein targeting to nucleus GO:0044744 3 0.022
cellular response to stress GO:0033554 62 0.022
nucleic acid templated transcription GO:0097659 181 0.022
regulation of transcription dna templated GO:0006355 213 0.022
locomotion GO:0040011 313 0.022
immune system process GO:0002376 241 0.022
cellular protein modification process GO:0006464 100 0.022
negative regulation of cell cycle GO:0045786 14 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
cell substrate adhesion GO:0031589 4 0.021
regulation of embryonic development GO:0045995 47 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
camera type eye morphogenesis GO:0048593 108 0.021
specification of axis polarity GO:0065001 4 0.021
regulation of protein catabolic process GO:0042176 1 0.021
blood vessel development GO:0001568 246 0.021
guanosine containing compound metabolic process GO:1901068 4 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
regulation of signal transduction GO:0009966 225 0.020
cellular amine metabolic process GO:0044106 2 0.020
organism emergence from protective structure GO:0071684 4 0.020
carbohydrate derivative metabolic process GO:1901135 61 0.020
negative regulation of mitosis GO:0045839 3 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.019
regulation of programmed cell death GO:0043067 101 0.019
cell morphogenesis GO:0000902 289 0.019
protein import GO:0017038 3 0.019
response to organic cyclic compound GO:0014070 51 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
generation of neurons GO:0048699 385 0.019
oocyte maturation GO:0001556 4 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
regulation of mitotic cell cycle embryonic GO:0009794 2 0.019
protein localization to nucleus GO:0034504 3 0.018
positive regulation of chromosome organization GO:2001252 1 0.018
embryonic organ development GO:0048568 381 0.018
negative regulation of signal transduction GO:0009968 94 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
cell motility GO:0048870 244 0.018
regulation of mitotic cell cycle phase transition GO:1901990 8 0.018
protein acylation GO:0043543 3 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
viral process GO:0016032 1 0.018
cell cycle process GO:0022402 53 0.018
cellular response to radiation GO:0071478 4 0.017
protein import into nucleus GO:0006606 3 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
tube morphogenesis GO:0035239 349 0.017
brain development GO:0007420 293 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
cognition GO:0050890 1 0.017
intracellular mrna localization GO:0008298 1 0.017
regulation of histone methylation GO:0031060 3 0.017
regulation of biosynthetic process GO:0009889 250 0.017
negative regulation of gene expression GO:0010629 65 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
regulation of multicellular organism growth GO:0040014 4 0.016
hatching GO:0035188 4 0.016
cell proliferation GO:0008283 80 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
chromosome organization involved in meiosis GO:0070192 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
camera type eye development GO:0043010 222 0.016
death GO:0016265 121 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
establishment of localization GO:0051234 244 0.016
gtp catabolic process GO:0006184 2 0.016
organic substance catabolic process GO:1901575 28 0.015
specification of symmetry GO:0009799 204 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
ras protein signal transduction GO:0007265 7 0.015
regulation of cell cycle GO:0051726 52 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
regulation of cell activation GO:0050865 1 0.015
negative regulation of protein transport GO:0051224 3 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.014
positive regulation of metabolic process GO:0009893 108 0.014
cellular response to external stimulus GO:0071496 2 0.014
hemopoiesis GO:0030097 183 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of cell death GO:0010941 103 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
rna biosynthetic process GO:0032774 181 0.014
regulation of protein metabolic process GO:0051246 56 0.014
chromosome organization GO:0051276 31 0.014
negative regulation of signaling GO:0023057 96 0.014
regulation of rna metabolic process GO:0051252 224 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
determination of left right symmetry GO:0007368 179 0.014
positive regulation of transport GO:0051050 2 0.014
regulation of binding GO:0051098 3 0.014
protein modification process GO:0036211 100 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
anterior posterior pattern specification GO:0009952 152 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
cell aging GO:0007569 2 0.013
multi organism cellular process GO:0044764 2 0.013
eye morphogenesis GO:0048592 144 0.013
neuron development GO:0048666 262 0.013
gtp metabolic process GO:0046039 4 0.013
protein complex disassembly GO:0043241 1 0.013
localization of cell GO:0051674 244 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
nucleotide metabolic process GO:0009117 28 0.013
regulation of mitochondrion organization GO:0010821 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of cell shape GO:0008360 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of organelle assembly GO:1902115 4 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
cellular component disassembly GO:0022411 1 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
phosphorus metabolic process GO:0006793 109 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
adult behavior GO:0030534 2 0.012
stem cell proliferation GO:0072089 4 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
female meiotic division GO:0007143 2 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
organelle fission GO:0048285 23 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
negative regulation of cell communication GO:0010648 96 0.012
lipid storage GO:0019915 1 0.012
protein homooligomerization GO:0051260 3 0.012
chemosensory behavior GO:0007635 1 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
response to transition metal nanoparticle GO:1990267 28 0.012
secondary metabolic process GO:0019748 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
membrane invagination GO:0010324 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
cellular response to organic substance GO:0071310 105 0.011
eye development GO:0001654 277 0.011
phagocytosis engulfment GO:0006911 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
regulation of protein targeting GO:1903533 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of cellular component organization GO:0051128 86 0.011
protein complex localization GO:0031503 1 0.011
response to abiotic stimulus GO:0009628 122 0.011
response to corticosteroid GO:0031960 1 0.011
nuclear import GO:0051170 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
phagocytosis GO:0006909 3 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
regulation of dna metabolic process GO:0051052 11 0.010
homeostatic process GO:0042592 142 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
eye photoreceptor cell development GO:0042462 30 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
protein ubiquitination GO:0016567 11 0.010
regulation of reproductive process GO:2000241 4 0.010
tube closure GO:0060606 1 0.010
hormone secretion GO:0046879 2 0.010
mitotic nuclear division GO:0007067 18 0.010
microtubule based process GO:0007017 60 0.010
spermatid development GO:0007286 2 0.010
ameboidal type cell migration GO:0001667 143 0.010
response to decreased oxygen levels GO:0036293 25 0.010
negative regulation of catabolic process GO:0009895 3 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
methylation GO:0032259 22 0.010

spc24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
nervous system disease DOID:863 0 0.016
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013