Danio rerio

48 known processes

tcf7l1b

transcription factor 7-like 1b (T-cell specific, HMG-box)

(Aliases: tcf3b)

tcf7l1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.600
Mouse Worm Fly
head development GO:0060322 303 0.581
regulation of gene expression GO:0010468 265 0.545
Zebrafish Mouse Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.422
Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.421
Mouse Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.408
Zebrafish Mouse Worm Fly
biosynthetic process GO:0009058 294 0.401
Zebrafish Mouse Worm Fly
chordate embryonic development GO:0043009 271 0.364
generation of neurons GO:0048699 385 0.359
brain development GO:0007420 293 0.342
embryo development ending in birth or egg hatching GO:0009792 271 0.323
nitrogen compound metabolic process GO:0006807 319 0.303
Mouse Worm Fly
eye development GO:0001654 277 0.302
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.291
Mouse Worm Fly
transcription dna templated GO:0006351 181 0.287
Mouse Worm Fly
regulation of developmental process GO:0050793 247 0.273
Zebrafish Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.263
Mouse Worm Fly
nucleic acid templated transcription GO:0097659 181 0.256
Mouse Worm Fly
camera type eye development GO:0043010 222 0.250
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.249
Mouse Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.242
Mouse Worm Fly
regionalization GO:0003002 274 0.235
aromatic compound biosynthetic process GO:0019438 217 0.235
Mouse Worm Fly
central nervous system development GO:0007417 387 0.227
morphogenesis of an epithelium GO:0002009 333 0.218
locomotion GO:0040011 313 0.217
Zebrafish
cellular biosynthetic process GO:0044249 286 0.217
Zebrafish Mouse Worm Fly
ion transport GO:0006811 114 0.215
anterior posterior pattern specification GO:0009952 152 0.215
cellular aromatic compound metabolic process GO:0006725 295 0.214
Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.211
Zebrafish Mouse Worm Fly
cellular ketone metabolic process GO:0042180 11 0.210
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.207
Fly
rna biosynthetic process GO:0032774 181 0.207
Mouse Worm Fly
sensory organ development GO:0007423 393 0.206
Zebrafish
cell migration GO:0016477 237 0.206
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.195
Mouse Worm Fly
spinal cord development GO:0021510 46 0.194
Zebrafish
single organism localization GO:1902578 225 0.194
Worm
maintenance of location GO:0051235 4 0.193
neuron development GO:0048666 262 0.191
Worm
regulation of biosynthetic process GO:0009889 250 0.189
Zebrafish Mouse Worm Fly
neuron projection guidance GO:0097485 86 0.188
organic cyclic compound metabolic process GO:1901360 301 0.187
Mouse Worm Fly
organic substance biosynthetic process GO:1901576 289 0.182
Zebrafish Mouse Worm Fly
regulation of cell differentiation GO:0045595 142 0.179
Zebrafish Mouse Worm Fly
nucleic acid metabolic process GO:0090304 244 0.173
Mouse Worm Fly
axonogenesis GO:0007409 152 0.173
cellular nitrogen compound metabolic process GO:0034641 290 0.171
Mouse Worm Fly
neuron differentiation GO:0030182 353 0.170
Zebrafish Worm
macromolecule biosynthetic process GO:0009059 227 0.168
Mouse Worm Fly
gene expression GO:0010467 252 0.165
Zebrafish Mouse Worm Fly
transport GO:0006810 220 0.165
Worm
regulation of biological quality GO:0065008 263 0.162
Zebrafish
cell projection morphogenesis GO:0048858 244 0.157
regulation of signal transduction GO:0009966 225 0.153
Zebrafish Fly
negative regulation of cellular process GO:0048523 283 0.148
Zebrafish Mouse Worm Fly
chemotaxis GO:0006935 104 0.146
axon guidance GO:0007411 86 0.146
regulation of epithelial cell proliferation GO:0050678 3 0.145
embryonic organ development GO:0048568 381 0.145
Zebrafish
establishment of localization GO:0051234 244 0.145
Worm
regulation of rna metabolic process GO:0051252 224 0.144
Mouse Worm Fly
signal transduction GO:0007165 455 0.143
Zebrafish Fly
regulation of signaling GO:0023051 235 0.143
Zebrafish Fly
single organism transport GO:0044765 206 0.132
Worm
cell motility GO:0048870 244 0.130
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.128
Mouse Worm Fly
notochord development GO:0030903 54 0.126
organic cyclic compound biosynthetic process GO:1901362 223 0.125
Mouse Worm Fly
taxis GO:0042330 109 0.124
tube morphogenesis GO:0035239 349 0.122
Zebrafish Worm
regulation of cellular biosynthetic process GO:0031326 245 0.121
Zebrafish Mouse Worm Fly
muscle cell development GO:0055001 115 0.121
Zebrafish
cellular component morphogenesis GO:0032989 336 0.118
regulation of cell fate specification GO:0042659 20 0.116
Worm
rna metabolic process GO:0016070 219 0.116
Mouse Worm Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.115
Mouse Worm Fly
cell part morphogenesis GO:0032990 246 0.111
cellular nitrogen compound biosynthetic process GO:0044271 218 0.109
Mouse Worm Fly
positive regulation of transport GO:0051050 2 0.108
regulation of metabolic process GO:0019222 359 0.107
Zebrafish Mouse Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.104
Mouse Worm Fly
calcium ion transport into cytosol GO:0060402 3 0.097
cellular macromolecule metabolic process GO:0044260 391 0.095
Mouse Worm Fly
heterocycle metabolic process GO:0046483 290 0.094
Mouse Worm Fly
proximal distal pattern formation GO:0009954 1 0.094
Worm
neural tube development GO:0021915 62 0.093
regulation of macromolecule biosynthetic process GO:0010556 225 0.093
Mouse Worm Fly
positive regulation of transcription dna templated GO:0045893 57 0.091
Mouse Worm Fly
neuron projection morphogenesis GO:0048812 161 0.091
guanosine containing compound catabolic process GO:1901069 2 0.088
larval development GO:0002164 2 0.088
Worm
oxoacid metabolic process GO:0043436 31 0.087
Zebrafish
stem cell proliferation GO:0072089 4 0.087
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.085
Mouse Worm Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.085
single organism metabolic process GO:0044710 217 0.083
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.082
Mouse Worm Fly
protein targeting to nucleus GO:0044744 3 0.081
muscle structure development GO:0061061 196 0.080
Zebrafish Worm
eye morphogenesis GO:0048592 144 0.080
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.079
developmental growth involved in morphogenesis GO:0060560 86 0.079
cardiac cell fate commitment GO:0060911 1 0.078
specification of symmetry GO:0009799 204 0.077
system process GO:0003008 185 0.077
Zebrafish Worm
lymph vessel development GO:0001945 27 0.077
regulation of catenin import into nucleus GO:0035412 2 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.077
negative regulation of metabolic process GO:0009892 86 0.075
Mouse Worm Fly
regulation of synapse assembly GO:0051963 3 0.075
cytosolic calcium ion transport GO:0060401 3 0.075
cell fate specification GO:0001708 68 0.075
Worm
regulation of multicellular organismal process GO:0051239 277 0.074
Zebrafish Mouse Worm Fly
negative regulation of chemotaxis GO:0050922 4 0.070
embryonic limb morphogenesis GO:0030326 2 0.070
positive regulation of stem cell proliferation GO:2000648 1 0.069
regulation of primary metabolic process GO:0080090 311 0.067
Zebrafish Mouse Worm Fly
regulation of cell communication GO:0010646 232 0.067
Zebrafish Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.067
Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.067
Zebrafish
skeletal system development GO:0001501 181 0.066
positive regulation of macromolecule metabolic process GO:0010604 93 0.066
Zebrafish Mouse Worm Fly
neuron projection development GO:0031175 180 0.066
regulation of cell proliferation GO:0042127 37 0.065
carboxylic acid metabolic process GO:0019752 22 0.065
Zebrafish
cell projection organization GO:0030030 284 0.065
response to organic substance GO:0010033 153 0.064
somatic muscle development GO:0007525 4 0.064
negative regulation of biological process GO:0048519 304 0.063
Zebrafish Mouse Worm Fly
cell migration involved in gastrulation GO:0042074 79 0.063
regulation of transcription dna templated GO:0006355 213 0.063
Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.062
Mouse Worm Fly
response to chemical GO:0042221 320 0.062
axon development GO:0061564 166 0.061
regulation of stem cell differentiation GO:2000736 4 0.061
Mouse
regulation of nervous system development GO:0051960 90 0.059
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.058
protein import into nucleus GO:0006606 3 0.057
skeletal system morphogenesis GO:0048705 102 0.057
morphogenesis of embryonic epithelium GO:0016331 30 0.057
nuclear import GO:0051170 3 0.056
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.056
regulation of anatomical structure morphogenesis GO:0022603 130 0.056
single organism nuclear import GO:1902593 3 0.056
regulation of multicellular organismal development GO:2000026 223 0.056
Zebrafish Worm
lipid storage GO:0019915 1 0.056
formation of primary germ layer GO:0001704 62 0.055
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.055
Mouse Worm Fly
stem cell maintenance GO:0019827 4 0.055
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.054
lymph vessel morphogenesis GO:0036303 25 0.054
determination of bilateral symmetry GO:0009855 204 0.054
hematopoietic or lymphoid organ development GO:0048534 191 0.054
cellular localization GO:0051641 97 0.053
aging GO:0007568 2 0.053
negative regulation of macromolecule metabolic process GO:0010605 76 0.052
Mouse Worm Fly
central nervous system neuron differentiation GO:0021953 74 0.052
Zebrafish
cell fate commitment GO:0045165 99 0.051
Worm
negative regulation of gene expression GO:0010629 65 0.051
Mouse Worm Fly
negative regulation of biosynthetic process GO:0009890 55 0.051
Mouse Worm Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.051
Mouse Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.051
Mouse Worm Fly
epithelial tube morphogenesis GO:0060562 148 0.050
establishment of protein localization to organelle GO:0072594 4 0.050
actin filament based movement GO:0030048 1 0.050
muscle fiber development GO:0048747 52 0.050
Zebrafish
diencephalon development GO:0021536 58 0.050
Zebrafish
muscle cell differentiation GO:0042692 139 0.050
Zebrafish
positive regulation of gene expression GO:0010628 71 0.050
Zebrafish Mouse Worm Fly
sequestering of calcium ion GO:0051208 3 0.049
regulation of neural precursor cell proliferation GO:2000177 3 0.049
stem cell differentiation GO:0048863 117 0.049
Zebrafish Mouse
lymphangiogenesis GO:0001946 25 0.049
phosphorus metabolic process GO:0006793 109 0.049
regulation of mesenchymal cell proliferation GO:0010464 1 0.048
negative regulation of sequestering of calcium ion GO:0051283 4 0.048
gtp metabolic process GO:0046039 4 0.047
positive regulation of cellular amine metabolic process GO:0033240 0 0.047
blood vessel development GO:0001568 246 0.047
growth GO:0040007 174 0.047
Zebrafish
negative regulation of rna metabolic process GO:0051253 48 0.046
Mouse Worm Fly
regulation of molecular function GO:0065009 70 0.046
single organism organelle organization GO:1902589 199 0.046
Worm
regulation of protein targeting GO:1903533 2 0.045
glial cell proliferation GO:0014009 4 0.045
positive regulation of catabolic process GO:0009896 4 0.044
positive regulation of cellular process GO:0048522 201 0.044
cartilage development GO:0051216 96 0.044
embryonic skeletal system development GO:0048706 97 0.044
sequestering of metal ion GO:0051238 3 0.044
single organism cellular localization GO:1902580 46 0.044
positive regulation of notch signaling pathway GO:0045747 3 0.044
regulation of response to stimulus GO:0048583 269 0.043
Zebrafish Fly
amine metabolic process GO:0009308 2 0.043
cilium morphogenesis GO:0060271 85 0.043
regulation of localization GO:0032879 104 0.043
Zebrafish Worm
neurotransmitter transport GO:0006836 2 0.043
cellular response to chemical stimulus GO:0070887 157 0.043
primary neural tube formation GO:0014020 1 0.042
dorsal ventral pattern formation GO:0009953 125 0.042
Zebrafish
negative regulation of nucleic acid templated transcription GO:1903507 45 0.042
Mouse Worm Fly
regulation of binding GO:0051098 3 0.042
cellular response to organic substance GO:0071310 105 0.042
embryonic skeletal system morphogenesis GO:0048704 93 0.042
gastrulation GO:0007369 208 0.041
Worm
transmembrane transport GO:0055085 120 0.041
cell substrate adhesion GO:0031589 4 0.041
positive regulation of rna metabolic process GO:0051254 59 0.041
Mouse Worm Fly
cellular component movement GO:0006928 335 0.041
Zebrafish
nuclear transport GO:0051169 4 0.041
digestive tract morphogenesis GO:0048546 231 0.040
Zebrafish Worm
mesenchymal cell proliferation GO:0010463 1 0.040
regulation of nucleoside metabolic process GO:0009118 2 0.040
mesenchymal cell development GO:0014031 78 0.040
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.039
regulation of cellular component movement GO:0051270 55 0.039
Zebrafish
negative regulation of signaling GO:0023057 96 0.039
Zebrafish
skeletal muscle organ development GO:0060538 78 0.039
myeloid cell differentiation GO:0030099 86 0.039
homeostatic process GO:0042592 142 0.039
Zebrafish
response to stress GO:0006950 263 0.038
Zebrafish
cell differentiation in spinal cord GO:0021515 40 0.038
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.038
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.038
Zebrafish
establishment of localization in cell GO:0051649 77 0.038
localization of cell GO:0051674 244 0.038
Zebrafish
regulation of synapse organization GO:0050807 3 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
specification of axis polarity GO:0065001 4 0.037
Worm
guanosine containing compound metabolic process GO:1901068 4 0.037
gtp catabolic process GO:0006184 2 0.037
epithelial cell differentiation GO:0030855 116 0.037
regulation of purine nucleotide catabolic process GO:0033121 2 0.037
determination of left right symmetry GO:0007368 179 0.037
transcription from rna polymerase ii promoter GO:0006366 80 0.036
Mouse Worm Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.036
Zebrafish
protein metabolic process GO:0019538 183 0.036
rostrocaudal neural tube patterning GO:0021903 29 0.036
multicellular organismal metabolic process GO:0044236 2 0.035
midbrain hindbrain boundary development GO:0030917 23 0.035
forebrain development GO:0030900 96 0.035
Zebrafish
protein import GO:0017038 3 0.035
response to drug GO:0042493 3 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.035
negative regulation of neurogenesis GO:0050768 20 0.035
cellular amine metabolic process GO:0044106 2 0.034
regulation of organ growth GO:0046620 3 0.034
somatic stem cell maintenance GO:0035019 1 0.034
Mouse
neural tube patterning GO:0021532 33 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.034
exocytosis GO:0006887 1 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
cell surface receptor signaling pathway GO:0007166 325 0.034
Zebrafish Fly
vasculature development GO:0001944 278 0.034
negative regulation of multicellular organismal process GO:0051241 69 0.033
Worm
embryonic organ morphogenesis GO:0048562 274 0.033
Zebrafish
release of sequestered calcium ion into cytosol GO:0051209 3 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
Worm
cell proliferation GO:0008283 80 0.033
positive regulation of nucleotide catabolic process GO:0030813 1 0.033
embryonic heart tube development GO:0035050 133 0.033
microtubule based process GO:0007017 60 0.033
Worm
protein localization to nucleus GO:0034504 3 0.033
somite development GO:0061053 96 0.032
Zebrafish
regulation of nucleotide catabolic process GO:0030811 2 0.032
negative regulation of wnt signaling pathway GO:0030178 30 0.032
Zebrafish
regulation of reproductive process GO:2000241 4 0.032
positive regulation of signal transduction GO:0009967 56 0.032
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.032
regulation of protein import into nucleus GO:0042306 2 0.032
synaptic vesicle transport GO:0048489 1 0.031
positive regulation of nucleoside metabolic process GO:0045979 1 0.031
organic acid metabolic process GO:0006082 31 0.031
Zebrafish
myotube differentiation GO:0014902 45 0.031
regulation of protein localization to nucleus GO:1900180 2 0.031
digestive tract development GO:0048565 265 0.031
Zebrafish Worm
neuroblast proliferation GO:0007405 2 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
regulation of protein binding GO:0043393 3 0.030
digestive system development GO:0055123 289 0.030
Zebrafish Worm
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.030
Worm
embryonic hemopoiesis GO:0035162 53 0.030
retina development in camera type eye GO:0060041 146 0.029
skin development GO:0043588 54 0.029
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.029
negative regulation of developmental process GO:0051093 65 0.029
Mouse Worm
neural tube formation GO:0001841 16 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
epithelial cell morphogenesis GO:0003382 2 0.028
cellular component disassembly GO:0022411 1 0.028
macromolecule localization GO:0033036 54 0.028
gland development GO:0048732 143 0.028
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.028
regulation of collateral sprouting in absence of injury GO:0048696 4 0.028
cellular component assembly GO:0022607 170 0.028
negative regulation of gliogenesis GO:0014014 1 0.028
positive regulation of map kinase activity GO:0043406 3 0.028
ion transmembrane transport GO:0034220 91 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
negative regulation of smoothened signaling pathway GO:0045879 6 0.027
fertilization GO:0009566 3 0.027
spermatid differentiation GO:0048515 2 0.027
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.027
glial cell migration GO:0008347 3 0.027
positive regulation of myeloid cell differentiation GO:0045639 2 0.026
positive regulation of embryonic development GO:0040019 3 0.026
negative regulation of response to stimulus GO:0048585 104 0.026
Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
negative regulation of reproductive process GO:2000242 3 0.026
compound eye development GO:0048749 2 0.026
macromolecule modification GO:0043412 111 0.026
heart looping GO:0001947 94 0.025
specification of organ identity GO:0010092 2 0.025
neurotransmitter secretion GO:0007269 2 0.025
hemopoiesis GO:0030097 183 0.025
positive regulation of cell cycle GO:0045787 3 0.025
mesenchyme development GO:0060485 127 0.025
Zebrafish
regulation of neuron projection development GO:0010975 40 0.025
negative regulation of signal transduction GO:0009968 94 0.025
Zebrafish
regulation of protein transport GO:0051223 3 0.024
regulation of multicellular organismal metabolic process GO:0044246 2 0.024
regulation of embryonic development GO:0045995 47 0.024
intestinal epithelial structure maintenance GO:0060729 7 0.024
Zebrafish
regulation of gtp catabolic process GO:0033124 2 0.024
tissue homeostasis GO:0001894 25 0.024
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.024
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.024
foregut morphogenesis GO:0007440 4 0.024
organic substance transport GO:0071702 58 0.023
cellular response to retinoic acid GO:0071300 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cell cycle GO:0007049 93 0.023
Worm
regulation of locomotion GO:0040012 55 0.023
Zebrafish
production of molecular mediator of immune response GO:0002440 2 0.023
cation homeostasis GO:0055080 33 0.023
regulation of myotube differentiation GO:0010830 2 0.023
epithelial structure maintenance GO:0010669 8 0.023
Zebrafish
ventral spinal cord development GO:0021517 35 0.023
organelle localization GO:0051640 49 0.023
homeostasis of number of cells within a tissue GO:0048873 4 0.022
Zebrafish
morphogenesis of an epithelial fold GO:0060571 1 0.022
heart development GO:0007507 313 0.022
Fly
protein secretion GO:0009306 1 0.022
exocrine system development GO:0035272 28 0.022
Fly
somitogenesis GO:0001756 87 0.022
Zebrafish
response to endogenous stimulus GO:0009719 83 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
regulation of cellular component size GO:0032535 30 0.021
hindbrain development GO:0030902 91 0.021
negative regulation of cell communication GO:0010648 96 0.021
Zebrafish
cellular protein catabolic process GO:0044257 4 0.021
regulation of neurogenesis GO:0050767 87 0.021
Zebrafish
synaptic target recognition GO:0008039 1 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
regulation of cell size GO:0008361 29 0.021
mesoderm development GO:0007498 88 0.021
Mouse Worm
regulation of intracellular protein transport GO:0033157 3 0.021
mitotic cell cycle GO:0000278 64 0.021
Worm
developmental process involved in reproduction GO:0003006 27 0.021
Worm
cellular cation homeostasis GO:0030003 17 0.021
ventral spinal cord interneuron differentiation GO:0021514 12 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
ameboidal type cell migration GO:0001667 143 0.020
Zebrafish
spermatid development GO:0007286 2 0.020
collagen metabolic process GO:0032963 2 0.020
midbrain development GO:0030901 28 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
cognition GO:0050890 1 0.020
cellular protein modification process GO:0006464 100 0.020
epithelial cell proliferation GO:0050673 17 0.020
stem cell division GO:0017145 1 0.020
motor neuron axon guidance GO:0008045 23 0.020
adult behavior GO:0030534 2 0.020
regulation of skeletal muscle fiber development GO:0048742 2 0.020
phagocytosis GO:0006909 3 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
aorta development GO:0035904 4 0.020
fat soluble vitamin metabolic process GO:0006775 4 0.019
neural crest cell migration GO:0001755 42 0.019
Zebrafish
atp catabolic process GO:0006200 4 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
pancreas development GO:0031016 84 0.019
endothelial cell fate commitment GO:0060839 3 0.019
ectoderm development GO:0007398 9 0.019
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
neuron fate commitment GO:0048663 26 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
axis specification GO:0009798 43 0.019
Mouse Worm
regulation of apoptotic process GO:0042981 98 0.019
anatomical structure arrangement GO:0048532 2 0.019
striated muscle cell development GO:0055002 108 0.019
Zebrafish
tissue regeneration GO:0042246 74 0.019
Zebrafish
positive regulation of cytoskeleton organization GO:0051495 3 0.019
multi organism process GO:0051704 134 0.019
erythrocyte differentiation GO:0030218 54 0.019
regulation of glial cell differentiation GO:0045685 4 0.019
reproduction GO:0000003 40 0.019
Worm
cell death GO:0008219 121 0.018
Worm
peptidyl lysine acetylation GO:0018394 2 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
negative regulation of axon guidance GO:1902668 1 0.018
actin mediated cell contraction GO:0070252 1 0.018
protein modification process GO:0036211 100 0.018
regeneration GO:0031099 91 0.018
Zebrafish
behavior GO:0007610 74 0.018
mesenchymal cell differentiation GO:0048762 87 0.018
Zebrafish
carbohydrate derivative metabolic process GO:1901135 61 0.017
ear development GO:0043583 127 0.017
positive regulation of biological process GO:0048518 253 0.017
positive regulation of neural precursor cell proliferation GO:2000179 1 0.017
regulation of cell projection assembly GO:0060491 4 0.017
bmp signaling pathway GO:0030509 52 0.017
anterior posterior axis specification GO:0009948 20 0.017
Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.017
cation transport GO:0006812 81 0.017
muscle organ development GO:0007517 101 0.017
Worm
camera type eye morphogenesis GO:0048593 108 0.017
Zebrafish
cell matrix adhesion GO:0007160 4 0.017
positive regulation of cellular biosynthetic process GO:0031328 68 0.017
Mouse Worm Fly
negative regulation of cellular metabolic process GO:0031324 77 0.017
Mouse Worm Fly
development of primary female sexual characteristics GO:0046545 4 0.017
appendage development GO:0048736 80 0.017
Zebrafish Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
regulation of cellular component organization GO:0051128 86 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
regulation of neuron differentiation GO:0045664 56 0.017
regulation of cell development GO:0060284 100 0.016
Zebrafish Mouse
collateral sprouting in absence of injury GO:0048669 4 0.016
cellular component biogenesis GO:0044085 178 0.016
ion homeostasis GO:0050801 41 0.016
positive regulation of biosynthetic process GO:0009891 68 0.016
Mouse Worm Fly
polarized epithelial cell differentiation GO:0030859 4 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
convergent extension GO:0060026 118 0.016
metal ion homeostasis GO:0055065 26 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
embryonic skeletal joint development GO:0072498 3 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.016
adherens junction organization GO:0034332 4 0.016
female gonad development GO:0008585 4 0.016
macromolecular complex disassembly GO:0032984 1 0.016
stem cell development GO:0048864 82 0.016
Zebrafish Mouse
regulation of cell substrate adhesion GO:0010810 1 0.016
protein localization GO:0008104 40 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
skeletal muscle tissue development GO:0007519 67 0.016
cardiac atrium development GO:0003230 4 0.016
negative chemotaxis GO:0050919 1 0.016
epithelial cell development GO:0002064 42 0.016
endosomal transport GO:0016197 2 0.016
regulation of cell shape GO:0008360 1 0.016
cardiocyte differentiation GO:0035051 44 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.015
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.015
segmentation GO:0035282 97 0.015
regulation of protein catabolic process GO:0042176 1 0.015
pronephros development GO:0048793 69 0.015
immune system development GO:0002520 191 0.015
cellular protein metabolic process GO:0044267 129 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
wound healing GO:0042060 90 0.015
Zebrafish
cell projection assembly GO:0030031 64 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
positive regulation of secretion GO:0051047 1 0.015
mesodermal cell differentiation GO:0048333 21 0.015
Worm
synaptic transmission cholinergic GO:0007271 4 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
regulation of cell activation GO:0050865 1 0.015
organophosphate metabolic process GO:0019637 37 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
b cell activation GO:0042113 2 0.015
regulation of gtpase activity GO:0043087 2 0.014
regulation of cell migration GO:0030334 40 0.014
Zebrafish
muscle tissue development GO:0060537 110 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
nucleotide metabolic process GO:0009117 28 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
Zebrafish Worm
positive regulation of cell differentiation GO:0045597 30 0.014
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
mesodermal cell fate commitment GO:0001710 14 0.014
Worm
regulation of catalytic activity GO:0050790 55 0.014

tcf7l1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
sensory system disease DOID:0050155 0 0.033
nervous system disease DOID:863 0 0.033