Danio rerio

0 known processes

sst2

somatostatin 2

(Aliases: SSII,PPSS2,som,smst,sst)

sst2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
adult behavior GO:0030534 2 0.437
endocrine system development GO:0035270 65 0.421
regulation of biological quality GO:0065008 263 0.406
endocrine pancreas development GO:0031018 27 0.402
transport GO:0006810 220 0.386
organic cyclic compound biosynthetic process GO:1901362 223 0.384
ion transmembrane transport GO:0034220 91 0.345
nucleic acid templated transcription GO:0097659 181 0.258
regulation of rna metabolic process GO:0051252 224 0.243
regulation of nitrogen compound metabolic process GO:0051171 251 0.243
signal transduction GO:0007165 455 0.241
cation transmembrane transport GO:0098655 65 0.229
response to organic substance GO:0010033 153 0.226
peptide transport GO:0015833 1 0.212
cellular response to endogenous stimulus GO:0071495 68 0.212
regulation of macromolecule biosynthetic process GO:0010556 225 0.201
nitrogen compound metabolic process GO:0006807 319 0.199
nitric oxide mediated signal transduction GO:0007263 2 0.193
heterocycle biosynthetic process GO:0018130 215 0.191
organic cyclic compound metabolic process GO:1901360 301 0.185
aromatic compound biosynthetic process GO:0019438 217 0.168
synaptic transmission cholinergic GO:0007271 4 0.165
cellular response to chemical stimulus GO:0070887 157 0.163
biosynthetic process GO:0009058 294 0.158
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.156
regulation of metabolic process GO:0019222 359 0.152
regulation of gene expression GO:0010468 265 0.146
response to stress GO:0006950 263 0.140
rna biosynthetic process GO:0032774 181 0.138
central nervous system development GO:0007417 387 0.137
regulation of biosynthetic process GO:0009889 250 0.136
gene expression GO:0010467 252 0.133
response to nicotine GO:0035094 2 0.131
nucleobase containing compound biosynthetic process GO:0034654 205 0.130
regulation of primary metabolic process GO:0080090 311 0.129
cellular modified amino acid metabolic process GO:0006575 3 0.121
cellular aromatic compound metabolic process GO:0006725 295 0.116
glandular epithelial cell differentiation GO:0002067 9 0.116
transcription dna templated GO:0006351 181 0.111
regionalization GO:0003002 274 0.108
regulation of hormone secretion GO:0046883 2 0.108
heterocycle metabolic process GO:0046483 290 0.106
response to chemical GO:0042221 320 0.105
cellular biosynthetic process GO:0044249 286 0.104
cellular nitrogen compound metabolic process GO:0034641 290 0.104
establishment of localization GO:0051234 244 0.103
transmembrane transport GO:0055085 120 0.100
regulation of macromolecule metabolic process GO:0060255 317 0.099
single organism localization GO:1902578 225 0.098
muscle structure development GO:0061061 196 0.097
cellular nitrogen compound biosynthetic process GO:0044271 218 0.094
pancreatic a cell development GO:0003322 2 0.092
regulation of cellular amino acid metabolic process GO:0006521 0 0.092
type b pancreatic cell development GO:0003323 4 0.092
cell fate specification involved in pattern specification GO:0060573 3 0.092
ion transport GO:0006811 114 0.091
cellular macromolecule biosynthetic process GO:0034645 224 0.090
negative regulation of gene expression GO:0010629 65 0.087
regulation of cellular metabolic process GO:0031323 320 0.087
regulation of multicellular organismal development GO:2000026 223 0.084
head development GO:0060322 303 0.081
nucleobase containing compound metabolic process GO:0006139 274 0.081
regulation of nucleic acid templated transcription GO:1903506 213 0.077
eye development GO:0001654 277 0.077
hormone secretion GO:0046879 2 0.077
cell cell signaling GO:0007267 52 0.076
cellular amine metabolic process GO:0044106 2 0.076
regulation of multicellular organismal process GO:0051239 277 0.076
cellular response to organic substance GO:0071310 105 0.075
cellular amino acid metabolic process GO:0006520 7 0.075
regulation of signaling GO:0023051 235 0.071
periodic partitioning GO:0007365 1 0.070
sensory organ development GO:0007423 393 0.070
single organism transport GO:0044765 206 0.069
negative regulation of hormone secretion GO:0046888 2 0.069
negative regulation of feeding behavior GO:2000252 2 0.067
regulation of response to nutrient levels GO:0032107 1 0.067
positive regulation of biological process GO:0048518 253 0.067
organic substance biosynthetic process GO:1901576 289 0.064
regulation of developmental process GO:0050793 247 0.061
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.060
monovalent inorganic cation transport GO:0015672 42 0.058
cellular amide metabolic process GO:0043603 4 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.057
organonitrogen compound metabolic process GO:1901564 74 0.056
regulation of protein binding GO:0043393 3 0.056
regulation of cellular biosynthetic process GO:0031326 245 0.056
regulation of signal transduction GO:0009966 225 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.056
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.055
rna metabolic process GO:0016070 219 0.055
locomotion GO:0040011 313 0.054
regulation of transcription dna templated GO:0006355 213 0.053
generation of neurons GO:0048699 385 0.053
cellular response to hormone stimulus GO:0032870 39 0.052
positive regulation of cellular amine metabolic process GO:0033240 0 0.052
developmental growth GO:0048589 166 0.052
endocardium formation GO:0060214 1 0.052
cell differentiation in spinal cord GO:0021515 40 0.052
cell migration GO:0016477 237 0.051
regulation of protein catabolic process GO:0042176 1 0.050
hematopoietic or lymphoid organ development GO:0048534 191 0.049
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.049
cell motility GO:0048870 244 0.049
regulation of cell communication GO:0010646 232 0.049
cell surface receptor signaling pathway GO:0007166 325 0.048
negative regulation of cellular process GO:0048523 283 0.048
synaptic transmission GO:0007268 35 0.048
positive regulation of cellular process GO:0048522 201 0.048
glucose homeostasis GO:0042593 1 0.048
response to biotic stimulus GO:0009607 97 0.047
regulation of axonogenesis GO:0050770 32 0.047
regulation of multicellular organism growth GO:0040014 4 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.046
response to endogenous stimulus GO:0009719 83 0.046
regulation of response to stimulus GO:0048583 269 0.045
alpha amino acid metabolic process GO:1901605 3 0.045
cation transport GO:0006812 81 0.045
ubiquitin dependent protein catabolic process GO:0006511 3 0.045
positive regulation of multicellular organismal process GO:0051240 52 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.044
behavior GO:0007610 74 0.044
regulation of rna biosynthetic process GO:2001141 213 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.043
amine metabolic process GO:0009308 2 0.043
cellular response to biotic stimulus GO:0071216 3 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.042
negative regulation of metabolic process GO:0009892 86 0.042
response to glucose GO:0009749 3 0.041
cellular macromolecule metabolic process GO:0044260 391 0.041
wound healing GO:0042060 90 0.039
response to nitrogen compound GO:1901698 19 0.039
transcription from rna polymerase ii promoter GO:0006366 80 0.039
growth GO:0040007 174 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.038
carboxylic acid metabolic process GO:0019752 22 0.038
cellular component biogenesis GO:0044085 178 0.038
cell part morphogenesis GO:0032990 246 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.035
intracellular signal transduction GO:0035556 85 0.035
cellular response to external stimulus GO:0071496 2 0.035
forebrain regionalization GO:0021871 4 0.034
localization of cell GO:0051674 244 0.034
negative regulation of rna metabolic process GO:0051253 48 0.034
larval development GO:0002164 2 0.034
macromolecule biosynthetic process GO:0009059 227 0.034
chordate embryonic development GO:0043009 271 0.034
regeneration GO:0031099 91 0.034
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
pancreas development GO:0031016 84 0.033
cell morphogenesis GO:0000902 289 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.033
response to organic cyclic compound GO:0014070 51 0.033
renal system development GO:0072001 94 0.032
neural tube patterning GO:0021532 33 0.032
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.031
negative regulation of nucleic acid templated transcription GO:1903507 45 0.031
response to hexose GO:0009746 3 0.031
positive regulation of catabolic process GO:0009896 4 0.031
apoptotic process GO:0006915 116 0.030
cell death GO:0008219 121 0.030
neuron differentiation GO:0030182 353 0.030
response to external stimulus GO:0009605 264 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.029
er nucleus signaling pathway GO:0006984 2 0.029
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.029
neuron development GO:0048666 262 0.029
positive regulation of gliogenesis GO:0014015 2 0.029
pronephros development GO:0048793 69 0.029
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.028
response to monosaccharide GO:0034284 3 0.028
sodium ion transmembrane transport GO:0035725 21 0.028
regulation of response to food GO:0032095 1 0.027
cellular ketone metabolic process GO:0042180 11 0.027
carbohydrate homeostasis GO:0033500 1 0.027
anterior posterior pattern specification GO:0009952 152 0.027
gtp catabolic process GO:0006184 2 0.027
response to carbohydrate GO:0009743 3 0.027
nitrogen compound transport GO:0071705 23 0.027
hepatocyte proliferation GO:0072574 2 0.027
erythrocyte development GO:0048821 24 0.026
metal ion transport GO:0030001 58 0.026
specification of symmetry GO:0009799 204 0.026
cell projection morphogenesis GO:0048858 244 0.026
mesenchyme development GO:0060485 127 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
cellular amino acid biosynthetic process GO:0008652 2 0.026
organic substance transport GO:0071702 58 0.025
cellular protein catabolic process GO:0044257 4 0.025
regulation of localization GO:0032879 104 0.025
multicellular organism growth GO:0035264 4 0.025
regulation of sodium ion transport GO:0002028 2 0.025
tissue regeneration GO:0042246 74 0.025
positive regulation of response to stimulus GO:0048584 80 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
skeletal system morphogenesis GO:0048705 102 0.025
negative regulation of biological process GO:0048519 304 0.024
multi organism process GO:0051704 134 0.024
regulation of jak stat cascade GO:0046425 3 0.024
notochord development GO:0030903 54 0.024
ovulation cycle GO:0042698 2 0.024
response to starvation GO:0042594 5 0.024
gas transport GO:0015669 3 0.024
inorganic cation transmembrane transport GO:0098662 50 0.023
response to hormone GO:0009725 48 0.023
oocyte maturation GO:0001556 4 0.023
protein secretion GO:0009306 1 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of neuron migration GO:2001222 2 0.022
response to bacterium GO:0009617 58 0.022
regulation of binding GO:0051098 3 0.022
muscle cell differentiation GO:0042692 139 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
chloride transmembrane transport GO:1902476 4 0.021
small molecule metabolic process GO:0044281 77 0.021
death GO:0016265 121 0.021
urogenital system development GO:0001655 97 0.021
oxoacid metabolic process GO:0043436 31 0.021
optic placode formation GO:0001743 4 0.021
phosphorus metabolic process GO:0006793 109 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
cellular response to stress GO:0033554 62 0.020
programmed cell death GO:0012501 119 0.020
peptide metabolic process GO:0006518 1 0.020
glucocorticoid metabolic process GO:0008211 2 0.020
regulation of cell death GO:0010941 103 0.020
gtp metabolic process GO:0046039 4 0.020
skeletal system development GO:0001501 181 0.020
neuronal stem cell maintenance GO:0097150 2 0.019
inorganic ion transmembrane transport GO:0098660 57 0.019
response to lipid GO:0033993 60 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
response to nutrient levels GO:0031667 10 0.019
enteroendocrine cell differentiation GO:0035883 9 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
organic acid metabolic process GO:0006082 31 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
rhombomere 6 development GO:0021572 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
cellular component movement GO:0006928 335 0.018
neuromuscular process controlling balance GO:0050885 3 0.018
photoreceptor cell fate commitment GO:0046552 1 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
regulation of cell morphogenesis GO:0022604 42 0.018
neuron projection development GO:0031175 180 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
ventral spinal cord interneuron fate commitment GO:0060579 3 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
positive regulation of signaling GO:0023056 56 0.018
positive regulation of transport GO:0051050 2 0.018
regulation of cell development GO:0060284 100 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
guanosine containing compound catabolic process GO:1901069 2 0.017
response to drug GO:0042493 3 0.017
lipid storage GO:0019915 1 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
dendrite guidance GO:0070983 0 0.017
guanosine containing compound metabolic process GO:1901068 4 0.016
stem cell proliferation GO:0072089 4 0.016
regulation of protein metabolic process GO:0051246 56 0.016
inner ear development GO:0048839 126 0.016
specification of organ axis polarity GO:0010084 2 0.016
regulation of cellular component movement GO:0051270 55 0.016
immune system process GO:0002376 241 0.016
embryonic organ development GO:0048568 381 0.016
cellular response to lipid GO:0071396 39 0.016
photoreceptor cell fate specification GO:0043704 1 0.016
regulation of type b pancreatic cell development GO:2000074 1 0.016
single organism nuclear import GO:1902593 3 0.016
protein targeting to nucleus GO:0044744 3 0.016
nucleic acid metabolic process GO:0090304 244 0.016
regulation of apoptotic process GO:0042981 98 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
cellular component morphogenesis GO:0032989 336 0.016
tissue remodeling GO:0048771 4 0.016
regulation of blood pressure GO:0008217 1 0.015
fin regeneration GO:0031101 51 0.015
homeostatic process GO:0042592 142 0.015
tube morphogenesis GO:0035239 349 0.015
response to other organism GO:0051707 97 0.015
positive regulation of gene expression GO:0010628 71 0.015
wnt signaling pathway GO:0016055 80 0.015
determination of bilateral symmetry GO:0009855 204 0.015
cellular response to starvation GO:0009267 1 0.015
female sex differentiation GO:0046660 4 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
protein heterooligomerization GO:0051291 1 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
positive regulation of neuron migration GO:2001224 2 0.015
regulation of nervous system development GO:0051960 90 0.014
translational initiation GO:0006413 3 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
lipid catabolic process GO:0016042 4 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
protein metabolic process GO:0019538 183 0.014
protein import into nucleus GO:0006606 3 0.014
muscle organ development GO:0007517 101 0.014
cellular protein metabolic process GO:0044267 129 0.014
foregut morphogenesis GO:0007440 4 0.014
axonogenesis GO:0007409 152 0.014
response to peptide hormone GO:0043434 6 0.014
regulation of programmed cell death GO:0043067 101 0.014
blood circulation GO:0008015 87 0.014
regulation of blood vessel size GO:0050880 2 0.014
mesenchymal cell development GO:0014031 78 0.014
catechol containing compound metabolic process GO:0009712 2 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.014
regulation of metal ion transport GO:0010959 4 0.013
negative regulation of endopeptidase activity GO:0010951 10 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
response to glucocorticoid GO:0051384 1 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
nuclear import GO:0051170 3 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
lipid digestion GO:0044241 3 0.013
specification of organ identity GO:0010092 2 0.013
response to wounding GO:0009611 116 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
response to oxygen containing compound GO:1901700 55 0.012
positive regulation of neural precursor cell proliferation GO:2000179 1 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
stem cell differentiation GO:0048863 117 0.012
negative regulation of heart contraction GO:0045822 2 0.012
negative regulation of signaling GO:0023057 96 0.012
protein import GO:0017038 3 0.012
response to radiation GO:0009314 51 0.012
ovulation cycle process GO:0022602 2 0.012
activation of mapk activity GO:0000187 3 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of catalytic activity GO:0050790 55 0.012
positive regulation of cytokine production GO:0001819 2 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
erythrocyte differentiation GO:0030218 54 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
mitochondrion organization GO:0007005 4 0.012
positive regulation of signal transduction GO:0009967 56 0.012
regulation of tube size GO:0035150 2 0.012
negative regulation of blood circulation GO:1903523 2 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
regulation of transport GO:0051049 45 0.011
developmental programmed cell death GO:0010623 4 0.011
positive regulation of blood circulation GO:1903524 2 0.011
gland development GO:0048732 143 0.011
embryonic skeletal joint development GO:0072498 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
auditory receptor cell fate determination GO:0042668 2 0.011
stem cell division GO:0017145 1 0.011
bone remodeling GO:0046849 2 0.011
sodium ion transport GO:0006814 24 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
response to steroid hormone GO:0048545 35 0.011
cell fate specification GO:0001708 68 0.011
regulation of reproductive process GO:2000241 4 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
syncytium formation GO:0006949 12 0.011
membrane repolarization GO:0086009 2 0.011
gastrulation GO:0007369 208 0.011
positive regulation of cell communication GO:0010647 56 0.011
catechol containing compound biosynthetic process GO:0009713 2 0.011
system process GO:0003008 185 0.011
glial cell fate specification GO:0021780 4 0.010
brain development GO:0007420 293 0.010
retina development in camera type eye GO:0060041 146 0.010
embryonic skeletal system development GO:0048706 97 0.010
response to alkaloid GO:0043279 2 0.010
epidermal cell fate specification GO:0009957 4 0.010
neuron fate specification GO:0048665 20 0.010
cell projection organization GO:0030030 284 0.010
regulation of organ growth GO:0046620 3 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
positive regulation of secretion GO:0051047 1 0.010
negative regulation of cell communication GO:0010648 96 0.010
nuclear transport GO:0051169 4 0.010
heart development GO:0007507 313 0.010

sst2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.171
disease of metabolism DOID:0014667 0 0.030
disease of cellular proliferation DOID:14566 0 0.025
diabetes mellitus DOID:9351 0 0.022
type 2 diabetes mellitus DOID:9352 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.022
glucose metabolism disease DOID:4194 0 0.022
acquired metabolic disease DOID:0060158 0 0.022
endocrine system disease DOID:28 0 0.018
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
cardiovascular system disease DOID:1287 0 0.011