Danio rerio

21 known processes

map2k7

mitogen-activated protein kinase kinase 7

(Aliases: MKK7,si:ch211-254d18.2)

map2k7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.277
hepatic duct development GO:0061011 2 0.255
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.229
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.205
thrombocyte differentiation GO:0002574 4 0.190
mediolateral intercalation GO:0060031 3 0.188
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.177
hepatocyte proliferation GO:0072574 2 0.165
gall bladder development GO:0061010 1 0.153
nitrogen compound metabolic process GO:0006807 319 0.144
Fly
morphogenesis of an epithelium GO:0002009 333 0.142
Fly
spinal cord anterior posterior patterning GO:0021512 1 0.136
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.134
regulation of metabolic process GO:0019222 359 0.134
Human Zebrafish Mouse Rat Worm Fly
negative regulation of nuclear division GO:0051784 3 0.125
regulation of anterior head development GO:2000742 2 0.122
determination of bilateral symmetry GO:0009855 204 0.112
Zebrafish
specification of symmetry GO:0009799 204 0.111
Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.110
Zebrafish
larval development GO:0002164 2 0.106
microtubule based process GO:0007017 60 0.105
convergent extension GO:0060026 118 0.105
signal transduction GO:0007165 455 0.102
Human Zebrafish Mouse Rat Worm Fly
tube morphogenesis GO:0035239 349 0.101
anterior head development GO:0097065 2 0.100
optic placode formation involved in camera type eye formation GO:0046619 3 0.096
cytokinesis GO:0000910 3 0.094
organic cyclic compound metabolic process GO:1901360 301 0.093
Fly
cell morphogenesis GO:0000902 289 0.089
Fly
single organism transport GO:0044765 206 0.089
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.089
Fly
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.089
negative regulation of sequestering of calcium ion GO:0051283 4 0.081
maintenance of location GO:0051235 4 0.080
convergent extension involved in gastrulation GO:0060027 71 0.080
somite development GO:0061053 96 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.077
Human Zebrafish Mouse Rat Worm Fly
regulation of protein catabolic process GO:0042176 1 0.077
sequestering of metal ion GO:0051238 3 0.077
cell projection morphogenesis GO:0048858 244 0.077
Fly
heterocycle metabolic process GO:0046483 290 0.076
Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.075
Zebrafish Mouse Rat Worm Fly
cell surface receptor signaling pathway GO:0007166 325 0.074
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.073
guanosine containing compound metabolic process GO:1901068 4 0.073
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.071
regulation of response to stimulus GO:0048583 269 0.071
Human Zebrafish Mouse Rat Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.071
single organism organelle organization GO:1902589 199 0.071
Fly
negative regulation of mitosis GO:0045839 3 0.070
cytoskeleton organization GO:0007010 96 0.069
Fly
determination of left right symmetry GO:0007368 179 0.069
organelle organization GO:0006996 227 0.068
Worm Fly
regulation of gene expression GO:0010468 265 0.068
Fly
single organism localization GO:1902578 225 0.068
Fly
optic placode formation GO:0001743 4 0.067
regulation of biological quality GO:0065008 263 0.067
Fly
proteasomal protein catabolic process GO:0010498 2 0.066
regulation of sequestering of calcium ion GO:0051282 4 0.065
sequestering of calcium ion GO:0051208 3 0.065
positive regulation of cellular component biogenesis GO:0044089 3 0.064
release of sequestered calcium ion into cytosol GO:0051209 3 0.060
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.059
positive regulation of catabolic process GO:0009896 4 0.059
Fly
guanosine containing compound catabolic process GO:1901069 2 0.059
ubiquitin dependent protein catabolic process GO:0006511 3 0.056
gtp metabolic process GO:0046039 4 0.056
positive regulation of jnk cascade GO:0046330 3 0.056
Zebrafish Mouse Rat Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.055
Fly
macromolecule biosynthetic process GO:0009059 227 0.055
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.055
Fly
regulation of primary metabolic process GO:0080090 311 0.055
Human Zebrafish Mouse Rat Worm Fly
golgi vesicle transport GO:0048193 3 0.055
regionalization GO:0003002 274 0.054
cellular response to external stimulus GO:0071496 2 0.053
cell migration involved in gastrulation GO:0042074 79 0.052
heart looping GO:0001947 94 0.052
regulation of cytokine production GO:0001817 3 0.052
digestive tract morphogenesis GO:0048546 231 0.052
heterocycle biosynthetic process GO:0018130 215 0.052
Fly
cellular macromolecule metabolic process GO:0044260 391 0.051
Human Zebrafish Mouse Rat Worm Fly
cellular component morphogenesis GO:0032989 336 0.051
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.051
Fly
negative regulation of biological process GO:0048519 304 0.051
nucleobase containing compound metabolic process GO:0006139 274 0.051
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.051
embryonic heart tube development GO:0035050 133 0.050
negative regulation of signaling GO:0023057 96 0.050
establishment of spindle orientation GO:0051294 10 0.049
cellular biosynthetic process GO:0044249 286 0.049
Fly
dorsal convergence GO:0060030 14 0.049
metal ion transport GO:0030001 58 0.049
cellular aromatic compound metabolic process GO:0006725 295 0.048
Fly
gastrulation GO:0007369 208 0.047
regulation of synapse organization GO:0050807 3 0.047
regulation of cellular biosynthetic process GO:0031326 245 0.047
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.047
digestive tract development GO:0048565 265 0.047
positive regulation of transport GO:0051050 2 0.047
stem cell maintenance GO:0019827 4 0.046
establishment of localization GO:0051234 244 0.046
Fly
calcium ion transport into cytosol GO:0060402 3 0.046
regulation of signal transduction GO:0009966 225 0.045
Human Zebrafish Mouse Rat Worm Fly
stem cell division GO:0017145 1 0.045
regulation of biosynthetic process GO:0009889 250 0.044
Fly
protein modification process GO:0036211 100 0.043
Human Zebrafish Mouse Rat Worm Fly
locomotion GO:0040011 313 0.043
Worm Fly
cellular response to nutrient levels GO:0031669 2 0.043
stem cell proliferation GO:0072089 4 0.043
regulation of rna metabolic process GO:0051252 224 0.042
Fly
protein targeting to nucleus GO:0044744 3 0.042
mitotic cell cycle process GO:1903047 48 0.041
protein metabolic process GO:0019538 183 0.041
Human Zebrafish Mouse Rat Worm Fly
liver development GO:0001889 96 0.041
cortical actin cytoskeleton organization GO:0030866 1 0.041
developmental cell growth GO:0048588 52 0.041
Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.041
cellular component movement GO:0006928 335 0.041
Fly
single organism metabolic process GO:0044710 217 0.041
Human Zebrafish Mouse Rat Worm Fly
immune system process GO:0002376 241 0.041
Fly
spindle localization GO:0051653 12 0.040
otolith development GO:0048840 32 0.040
mitotic cell cycle GO:0000278 64 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.039
Fly
meiotic cell cycle process GO:1903046 3 0.039
habenula development GO:0021986 9 0.039
gene expression GO:0010467 252 0.038
Fly
embryonic organ morphogenesis GO:0048562 274 0.038
muscle cell differentiation GO:0042692 139 0.038
regulation of nucleoside metabolic process GO:0009118 2 0.038
positive regulation of biological process GO:0048518 253 0.038
Human Zebrafish Mouse Rat Worm Fly
negative regulation of cellular process GO:0048523 283 0.038
dorsal ventral pattern formation GO:0009953 125 0.038
Zebrafish
regulation of signaling GO:0023051 235 0.038
Human Zebrafish Mouse Rat Worm Fly
response to external stimulus GO:0009605 264 0.038
Worm
cellular response to extracellular stimulus GO:0031668 2 0.038
sensory organ development GO:0007423 393 0.038
muscle structure development GO:0061061 196 0.037
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.037
Zebrafish Mouse Rat Worm Fly
regulation of epithelial cell proliferation GO:0050678 3 0.037
cell part morphogenesis GO:0032990 246 0.037
Fly
embryonic limb morphogenesis GO:0030326 2 0.037
cellular response to starvation GO:0009267 1 0.037
rna metabolic process GO:0016070 219 0.037
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.037
Fly
positive regulation of protein complex assembly GO:0031334 2 0.037
microtubule cytoskeleton organization GO:0000226 33 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.036
nuclear import GO:0051170 3 0.036
meiotic nuclear division GO:0007126 4 0.036
Worm
response to chemical GO:0042221 320 0.036
Human Rat Worm Fly
canonical wnt signaling pathway GO:0060070 48 0.036
regulation of mrna splicing via spliceosome GO:0048024 3 0.035
brain development GO:0007420 293 0.035
digestive system development GO:0055123 289 0.035
negative regulation of signal transduction GO:0009968 94 0.035
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.035
central nervous system development GO:0007417 387 0.035
cytoskeleton dependent cytokinesis GO:0061640 3 0.035
protein import GO:0017038 3 0.035
organelle localization GO:0051640 49 0.035
cilium assembly GO:0042384 58 0.034
negative regulation of response to stimulus GO:0048585 104 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
Fly
actin polymerization or depolymerization GO:0008154 2 0.034
regulation of protein complex assembly GO:0043254 3 0.034
cortical cytoskeleton organization GO:0030865 1 0.034
nephron morphogenesis GO:0072028 2 0.034
embryonic heart tube morphogenesis GO:0003143 108 0.034
axon development GO:0061564 166 0.034
Fly
establishment of mitotic spindle orientation GO:0000132 10 0.034
cellular component disassembly GO:0022411 1 0.034
Fly
cytosolic calcium ion transport GO:0060401 3 0.033
regulation of gtp catabolic process GO:0033124 2 0.033
cellular component biogenesis GO:0044085 178 0.033
Fly
gtp catabolic process GO:0006184 2 0.033
hepaticobiliary system development GO:0061008 98 0.033
protein import into nucleus GO:0006606 3 0.033
epithelial tube morphogenesis GO:0060562 148 0.033
cilium organization GO:0044782 71 0.033
heart development GO:0007507 313 0.032
cellular protein catabolic process GO:0044257 4 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
Fly
negative regulation of wnt signaling pathway GO:0030178 30 0.032
nucleic acid metabolic process GO:0090304 244 0.032
Fly
immune system development GO:0002520 191 0.032
somatic stem cell maintenance GO:0035019 1 0.032
chordate embryonic development GO:0043009 271 0.032
epithalamus development GO:0021538 10 0.032
peptidyl serine modification GO:0018209 2 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
Fly
peptidyl serine phosphorylation GO:0018105 1 0.032
hematopoietic or lymphoid organ development GO:0048534 191 0.032
organelle fusion GO:0048284 3 0.031
regulation of synapse assembly GO:0051963 3 0.031
multicellular organism growth GO:0035264 4 0.031
determination of heart left right asymmetry GO:0061371 117 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
Human Zebrafish Mouse Rat Worm Fly
gland development GO:0048732 143 0.030
response to stress GO:0006950 263 0.030
Human Zebrafish Mouse Rat Worm Fly
protein localization to plasma membrane GO:0072659 1 0.030
phosphorus metabolic process GO:0006793 109 0.030
Human Zebrafish Mouse Rat Worm Fly
cellular protein modification process GO:0006464 100 0.030
Human Zebrafish Mouse Rat Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.030
Fly
establishment of protein localization to organelle GO:0072594 4 0.030
neuroblast proliferation GO:0007405 2 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
protein complex disassembly GO:0043241 1 0.029
cellular response to organic substance GO:0071310 105 0.029
Rat
aging GO:0007568 2 0.029
Fly
ion transport GO:0006811 114 0.029
segmentation GO:0035282 97 0.029
generation of neurons GO:0048699 385 0.029
Fly
cell projection organization GO:0030030 284 0.029
Fly
establishment of endothelial barrier GO:0061028 3 0.029
cellular component assembly GO:0022607 170 0.029
Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.029
ear morphogenesis GO:0042471 64 0.028
regulation of cell substrate adhesion GO:0010810 1 0.028
muscle cell development GO:0055001 115 0.028
ear development GO:0043583 127 0.028
regulation of mrna processing GO:0050684 3 0.028
otic vesicle development GO:0071599 42 0.028
negative regulation of cell communication GO:0010648 96 0.028
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.027
melanin metabolic process GO:0006582 2 0.027
Fly
inner ear development GO:0048839 126 0.027
embryonic neurocranium morphogenesis GO:0048702 15 0.027
regulation of neuron differentiation GO:0045664 56 0.027
regulation of nucleotide catabolic process GO:0030811 2 0.027
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.027
somitogenesis GO:0001756 87 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
Fly
spindle assembly GO:0051225 2 0.027
mitochondrion organization GO:0007005 4 0.027
regulation of multicellular organismal development GO:2000026 223 0.026
autophagy GO:0006914 4 0.026
Fly
spemann organizer formation GO:0060061 10 0.026
neuron projection morphogenesis GO:0048812 161 0.026
Fly
determination of dorsal identity GO:0048263 13 0.026
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.026
Human Zebrafish Mouse Rat Worm Fly
striated muscle cell differentiation GO:0051146 129 0.026
specification of organ identity GO:0010092 2 0.026
response to corticosteroid GO:0031960 1 0.026
cell migration GO:0016477 237 0.026
Fly
lateral line development GO:0048882 66 0.026
regulation of developmental process GO:0050793 247 0.026
Fly
otic vesicle morphogenesis GO:0071600 34 0.026
estrogen metabolic process GO:0008210 2 0.026
hemopoiesis GO:0030097 183 0.026
ectodermal placode morphogenesis GO:0071697 32 0.026
protein polymerization GO:0051258 4 0.026
macroautophagy GO:0016236 1 0.026
cell death GO:0008219 121 0.026
Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
regulation of cell development GO:0060284 100 0.025
cellular amine metabolic process GO:0044106 2 0.025
wnt signaling pathway GO:0016055 80 0.025
regulation of axon extension GO:0030516 24 0.025
embryonic organ development GO:0048568 381 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
positive regulation of striated muscle tissue development GO:0045844 1 0.025
ribosomal small subunit biogenesis GO:0042274 2 0.025
neuromast development GO:0048884 46 0.025
regulation of cell projection assembly GO:0060491 4 0.025
nuclear transport GO:0051169 4 0.025
regulation of dendrite development GO:0050773 3 0.025
cell growth GO:0016049 57 0.025
Fly
endosomal transport GO:0016197 2 0.025
sensory system development GO:0048880 76 0.025
ventricular system development GO:0021591 12 0.024
protein localization to nucleus GO:0034504 3 0.024
rostrocaudal neural tube patterning GO:0021903 29 0.024
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.024
regulation of protein polymerization GO:0032271 2 0.024
positive regulation of cytoskeleton organization GO:0051495 3 0.024
activation of jun kinase activity GO:0007257 2 0.024
Zebrafish Mouse Rat Worm
connective tissue development GO:0061448 99 0.024
ectodermal placode development GO:0071696 37 0.024
spindle assembly involved in mitosis GO:0090307 1 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
Rat Fly
somatic muscle development GO:0007525 4 0.024
response to external biotic stimulus GO:0043207 97 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
Fly
regulation of cell communication GO:0010646 232 0.023
Human Zebrafish Mouse Rat Worm Fly
establishment of cell polarity GO:0030010 18 0.023
kupffer s vesicle development GO:0070121 50 0.023
female sex differentiation GO:0046660 4 0.023
regulation of cell differentiation GO:0045595 142 0.023
Fly
membrane fusion GO:0061025 2 0.023
regulation of cell morphogenesis GO:0022604 42 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
cytokinetic process GO:0032506 2 0.023
macromolecule modification GO:0043412 111 0.023
Human Zebrafish Mouse Rat Worm Fly
adherens junction organization GO:0034332 4 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
cellular protein metabolic process GO:0044267 129 0.022
Human Zebrafish Mouse Rat Worm Fly
cilium morphogenesis GO:0060271 85 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
macromolecular complex disassembly GO:0032984 1 0.022
positive regulation of muscle organ development GO:0048636 1 0.022
regulation of cardiac muscle tissue development GO:0055024 1 0.022
transcription dna templated GO:0006351 181 0.022
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
amine metabolic process GO:0009308 2 0.022
nephron epithelium morphogenesis GO:0072088 1 0.022
non canonical wnt signaling pathway GO:0035567 13 0.022
positive regulation of cellular process GO:0048522 201 0.022
Human Zebrafish Mouse Rat Worm Fly
single organism cellular localization GO:1902580 46 0.022
ribonucleotide metabolic process GO:0009259 27 0.021
embryonic skeletal system development GO:0048706 97 0.021
protein complex localization GO:0031503 1 0.021
female gonad development GO:0008585 4 0.021
protein polyubiquitination GO:0000209 4 0.021
positive regulation of neuron death GO:1901216 1 0.021
Rat
regulation of protein localization to nucleus GO:1900180 2 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
skeletal system development GO:0001501 181 0.021
membrane invagination GO:0010324 1 0.021
Fly
organonitrogen compound metabolic process GO:1901564 74 0.021
microtubule based movement GO:0007018 33 0.021
regulation of axonogenesis GO:0050770 32 0.021
unidimensional cell growth GO:0009826 5 0.021
positive regulation of neuron apoptotic process GO:0043525 1 0.021
Rat
regulation of neurogenesis GO:0050767 87 0.021
meiotic chromosome segregation GO:0045132 3 0.021
neuron differentiation GO:0030182 353 0.021
Fly
regulation of cellular amine metabolic process GO:0033238 0 0.021
alternative mrna splicing via spliceosome GO:0000380 1 0.021
negative regulation of cell fate commitment GO:0010454 13 0.021
positive regulation of cell cycle GO:0045787 3 0.021
positive regulation of muscle tissue development GO:1901863 1 0.021
cell motility GO:0048870 244 0.021
Fly
cellular amino acid metabolic process GO:0006520 7 0.020
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
heart morphogenesis GO:0003007 156 0.020
nephron tubule morphogenesis GO:0072078 1 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
Fly
single organism membrane fusion GO:0044801 2 0.020
positive regulation of gtpase activity GO:0043547 1 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
neuron development GO:0048666 262 0.020
Fly
programmed cell death GO:0012501 119 0.020
Rat
positive regulation of jun kinase activity GO:0043507 2 0.020
Zebrafish Mouse Rat Worm Fly
muscle fiber development GO:0048747 52 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
Fly
forebrain generation of neurons GO:0021872 14 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
regulation of binding GO:0051098 3 0.020
negative regulation of catabolic process GO:0009895 3 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
chemosensory behavior GO:0007635 1 0.020
striated muscle cell development GO:0055002 108 0.020
response to alkaloid GO:0043279 2 0.020
lamellipodium assembly GO:0030032 1 0.020
Fly
cellular ketone metabolic process GO:0042180 11 0.019
organic substance biosynthetic process GO:1901576 289 0.019
Fly
negative regulation of kinase activity GO:0033673 4 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.019
superoxide metabolic process GO:0006801 2 0.019
blood vessel development GO:0001568 246 0.019
anterior posterior pattern specification GO:0009952 152 0.019
regulation of cell shape GO:0008360 1 0.019
gastrulation with mouth forming second GO:0001702 44 0.019
inner ear morphogenesis GO:0042472 63 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
cell substrate adhesion GO:0031589 4 0.019
regulation of chromosome segregation GO:0051983 1 0.019
cellular localization GO:0051641 97 0.019
positive regulation of signaling GO:0023056 56 0.019
Human Zebrafish Mouse Rat Worm Fly
growth GO:0040007 174 0.019
Worm Fly
establishment of organelle localization GO:0051656 45 0.019
nucleic acid templated transcription GO:0097659 181 0.019
Fly
organelle assembly GO:0070925 110 0.019
homeostatic process GO:0042592 142 0.019
Fly
neurotransmitter transport GO:0006836 2 0.019
biosynthetic process GO:0009058 294 0.019
Fly
regulation of cellular component organization GO:0051128 86 0.019
axon guidance GO:0007411 86 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
regulation of cell growth GO:0001558 29 0.018
rna biosynthetic process GO:0032774 181 0.018
Fly
apoptotic process involved in development GO:1902742 2 0.018
positive regulation of metabolic process GO:0009893 108 0.018
Human Zebrafish Mouse Rat Worm Fly
neuron projection extension GO:1990138 45 0.018
Fly
keratinocyte differentiation GO:0030216 0 0.018
vasculature development GO:0001944 278 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
establishment of blood brain barrier GO:0060856 2 0.018
lateral line system development GO:0048925 76 0.018
transport GO:0006810 220 0.018
Fly
cell cycle GO:0007049 93 0.018
Worm
regulation of skeletal muscle tissue development GO:0048641 4 0.018
response to glucocorticoid GO:0051384 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
Fly
regulation of apoptotic process GO:0042981 98 0.018
Rat
neural plate development GO:0001840 10 0.018
positive regulation of striated muscle cell differentiation GO:0051155 1 0.018
response to other organism GO:0051707 97 0.018
pancreas development GO:0031016 84 0.018
cellular response to xenobiotic stimulus GO:0071466 35 0.018
establishment of mitotic spindle localization GO:0040001 12 0.018
neurotransmitter secretion GO:0007269 2 0.018
regulation of protein transport GO:0051223 3 0.017
epithelium regeneration GO:1990399 14 0.017
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.017
regulation of cell projection organization GO:0031344 44 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
regulation of gtpase activity GO:0043087 2 0.017
xenobiotic metabolic process GO:0006805 4 0.017
mitotic nuclear division GO:0007067 18 0.017
common bile duct development GO:0061009 13 0.017
specification of axis polarity GO:0065001 4 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of cell matrix adhesion GO:0001952 1 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
establishment of spindle localization GO:0051293 12 0.017
regulation of bone mineralization GO:0030500 2 0.017
lamellipodium organization GO:0097581 1 0.017
Fly
swim bladder development GO:0048794 19 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
central nervous system neuron differentiation GO:0021953 74 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
secondary metabolic process GO:0019748 3 0.017
Fly
cation transport GO:0006812 81 0.017
regulation of reproductive process GO:2000241 4 0.017
tube closure GO:0060606 1 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
Fly
diencephalon development GO:0021536 58 0.017
localization of cell GO:0051674 244 0.016
Fly
compound eye development GO:0048749 2 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
liver morphogenesis GO:0072576 8 0.016
regulation of protein complex disassembly GO:0043244 1 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
wound healing GO:0042060 90 0.016
Fly
fourth ventricle development GO:0021592 8 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
centrosome localization GO:0051642 1 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
axis elongation GO:0003401 31 0.016
renal tubule morphogenesis GO:0061333 1 0.016
establishment or maintenance of cell polarity GO:0007163 29 0.016
otic vesicle formation GO:0030916 27 0.016
neutrophil mediated immunity GO:0002446 1 0.016
tissue regeneration GO:0042246 74 0.016
actin filament based movement GO:0030048 1 0.016
regulation of establishment of planar polarity GO:0090175 4 0.016
ectoderm development GO:0007398 9 0.016
ectodermal placode formation GO:0060788 26 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
midbrain hindbrain boundary development GO:0030917 23 0.016
er to golgi vesicle mediated transport GO:0006888 1 0.016
rho protein signal transduction GO:0007266 5 0.016
embryonic camera type eye morphogenesis GO:0048596 19 0.016
sensory epithelium regeneration GO:0070654 14 0.016
spermatid differentiation GO:0048515 2 0.016
regulation of nervous system development GO:0051960 90 0.016
head development GO:0060322 303 0.016
forebrain development GO:0030900 96 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
phosphorylation GO:0016310 69 0.015
Human Zebrafish Mouse Rat Worm Fly
response to wounding GO:0009611 116 0.015
Fly
regulation of catalytic activity GO:0050790 55 0.015
Human Zebrafish Mouse Rat Worm Fly
regulation of protein ubiquitination GO:0031396 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of cell size GO:0008361 29 0.015
microtubule polymerization or depolymerization GO:0031109 3 0.015
eye development GO:0001654 277 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
regulation of axon guidance GO:1902667 8 0.015
response to uv GO:0009411 3 0.015
Human
protein localization GO:0008104 40 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
sensory perception of touch GO:0050975 2 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
single organismal cell cell adhesion GO:0016337 29 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of canonical wnt signaling pathway GO:0060828 34 0.015
muscle organ development GO:0007517 101 0.015

map2k7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017