Danio rerio

0 known processes

map2k6

mitogen-activated protein kinase kinase 6

(Aliases: map2k3,zMKK3,MKK3)

map2k6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.186
Worm
regulation of metabolic process GO:0019222 359 0.185
Human Zebrafish Mouse Worm
regionalization GO:0003002 274 0.150
Zebrafish
meiotic nuclear division GO:0007126 4 0.126
synaptic growth at neuromuscular junction GO:0051124 2 0.113
regulation of developmental process GO:0050793 247 0.113
organic substance biosynthetic process GO:1901576 289 0.110
Human Mouse Worm
multi organism process GO:0051704 134 0.109
Worm
cellular biosynthetic process GO:0044249 286 0.104
Human Mouse Worm
stem cell maintenance GO:0019827 4 0.103
regulation of macromolecule biosynthetic process GO:0010556 225 0.102
Human Mouse Worm
positive regulation of cellular component biogenesis GO:0044089 3 0.100
developmental growth GO:0048589 166 0.097
regulation of nitrogen compound metabolic process GO:0051171 251 0.097
Human Worm
cell migration GO:0016477 237 0.097
single organism organelle organization GO:1902589 199 0.088
locomotion GO:0040011 313 0.087
regulation of gene expression GO:0010468 265 0.086
Human Worm
regulation of dna replication GO:0006275 3 0.080
localization of cell GO:0051674 244 0.079
positive regulation of jun kinase activity GO:0043507 2 0.078
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.078
response to stress GO:0006950 263 0.076
Zebrafish Mouse Worm
response to external stimulus GO:0009605 264 0.075
Worm
mitotic dna integrity checkpoint GO:0044774 4 0.074
nitrogen compound metabolic process GO:0006807 319 0.073
Human Worm
positive regulation of biological process GO:0048518 253 0.073
Human Zebrafish Mouse Worm
regulation of biological quality GO:0065008 263 0.072
multicellular organism growth GO:0035264 4 0.071
cellular macromolecule biosynthetic process GO:0034645 224 0.071
Human Worm
regulation of multicellular organism growth GO:0040014 4 0.070
cellular macromolecule metabolic process GO:0044260 391 0.070
Human Zebrafish Mouse Worm
regulation of macromolecule metabolic process GO:0060255 317 0.069
Human Zebrafish Mouse Worm
response to abiotic stimulus GO:0009628 122 0.066
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.066
organelle organization GO:0006996 227 0.066
aging GO:0007568 2 0.066
negative regulation of multicellular organismal process GO:0051241 69 0.065
biosynthetic process GO:0009058 294 0.064
Human Mouse Worm
mitotic g2 m transition checkpoint GO:0044818 3 0.064
central nervous system development GO:0007417 387 0.064
response to uv GO:0009411 3 0.062
behavior GO:0007610 74 0.061
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.060
cellular nitrogen compound metabolic process GO:0034641 290 0.059
Human Worm
positive regulation of protein complex assembly GO:0031334 2 0.059
regulation of mrna splicing via spliceosome GO:0048024 3 0.059
embryonic organ development GO:0048568 381 0.058
stem cell division GO:0017145 1 0.058
regulation of transcription dna templated GO:0006355 213 0.057
Human Worm
cell surface receptor signaling pathway GO:0007166 325 0.055
positive regulation of multicellular organismal process GO:0051240 52 0.055
Worm
gene expression GO:0010467 252 0.054
Human Worm
stem cell proliferation GO:0072089 4 0.054
negative regulation of kinase activity GO:0033673 4 0.054
mitotic cell cycle GO:0000278 64 0.054
cell cycle g1 s phase transition GO:0044843 1 0.053
oogenesis GO:0048477 14 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.053
Human Worm
regulation of cellular component organization GO:0051128 86 0.053
stem cell development GO:0048864 82 0.052
nucleic acid metabolic process GO:0090304 244 0.052
Human Worm
neuroblast proliferation GO:0007405 2 0.051
lamellipodium assembly GO:0030032 1 0.051
cell cycle GO:0007049 93 0.050
regulation of multicellular organismal process GO:0051239 277 0.050
Mouse Worm
mesenchymal cell differentiation GO:0048762 87 0.049
stem cell differentiation GO:0048863 117 0.048
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.048
dorsal ventral pattern formation GO:0009953 125 0.048
Zebrafish
cell motility GO:0048870 244 0.047
cell projection organization GO:0030030 284 0.046
meiotic cell cycle process GO:1903046 3 0.046
regulation of protein import into nucleus GO:0042306 2 0.045
signal transduction GO:0007165 455 0.045
Zebrafish Mouse Worm
cell cycle process GO:0022402 53 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Zebrafish
response to radiation GO:0009314 51 0.044
chordate embryonic development GO:0043009 271 0.044
Zebrafish
regulation of cytoplasmic transport GO:1903649 4 0.044
head development GO:0060322 303 0.044
regulation of cellular biosynthetic process GO:0031326 245 0.043
Human Mouse Worm
neuron differentiation GO:0030182 353 0.043
regulation of protein complex assembly GO:0043254 3 0.043
response to chemical GO:0042221 320 0.042
Worm
cytoskeleton organization GO:0007010 96 0.042
negative regulation of response to stimulus GO:0048585 104 0.042
positive regulation of cellular process GO:0048522 201 0.041
Human Zebrafish Mouse Worm
muscle structure development GO:0061061 196 0.041
mitotic g2 dna damage checkpoint GO:0007095 3 0.041
negative regulation of mitotic cell cycle GO:0045930 11 0.040
growth GO:0040007 174 0.040
regulation of cell cycle GO:0051726 52 0.040
negative regulation of protein phosphorylation GO:0001933 4 0.039
axon development GO:0061564 166 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
organic cyclic compound metabolic process GO:1901360 301 0.038
Human Worm
nuclear import GO:0051170 3 0.038
cellular response to stress GO:0033554 62 0.038
Zebrafish Worm
regulation of cell communication GO:0010646 232 0.038
Zebrafish Mouse Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.038
Human Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
Human Worm
generation of neurons GO:0048699 385 0.038
regulation of rna metabolic process GO:0051252 224 0.037
Human Worm
protein localization to nucleus GO:0034504 3 0.036
heart development GO:0007507 313 0.036
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
system process GO:0003008 185 0.035
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.035
regulation of protein catabolic process GO:0042176 1 0.035
single organism nuclear import GO:1902593 3 0.035
negative regulation of protein kinase activity GO:0006469 4 0.035
single organism metabolic process GO:0044710 217 0.035
Zebrafish Mouse Worm
regulation of protein ubiquitination GO:0031396 3 0.035
regulation of response to stimulus GO:0048583 269 0.034
Zebrafish Mouse Worm
somitogenesis GO:0001756 87 0.034
Zebrafish
mesenchymal cell development GO:0014031 78 0.034
translational initiation GO:0006413 3 0.034
regulation of synapse assembly GO:0051963 3 0.034
nuclear transport GO:0051169 4 0.033
reproduction GO:0000003 40 0.033
Worm
cellular component movement GO:0006928 335 0.033
protein polymerization GO:0051258 4 0.033
axonogenesis GO:0007409 152 0.032
cellular component assembly GO:0022607 170 0.032
regulation of jun kinase activity GO:0043506 3 0.032
Zebrafish
negative regulation of cell cycle GO:0045786 14 0.032
axon guidance GO:0007411 86 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
cellular component morphogenesis GO:0032989 336 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
intracellular signal transduction GO:0035556 85 0.031
Zebrafish Mouse Worm
multi organism reproductive process GO:0044703 36 0.031
Worm
mesoderm development GO:0007498 88 0.031
specification of organ identity GO:0010092 2 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
Worm
regulation of mitotic cell cycle GO:0007346 25 0.031
cell death GO:0008219 121 0.031
regulation of protein transport GO:0051223 3 0.031
post anal tail morphogenesis GO:0036342 19 0.031
locomotor rhythm GO:0045475 3 0.030
protein import GO:0017038 3 0.030
cellular component biogenesis GO:0044085 178 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
positive regulation of map kinase activity GO:0043406 3 0.030
Zebrafish Mouse Worm
spermatid differentiation GO:0048515 2 0.029
response to light stimulus GO:0009416 46 0.029
regulation of signal transduction GO:0009966 225 0.029
Zebrafish Mouse Worm
negative regulation of synapse assembly GO:0051964 2 0.029
sister chromatid cohesion GO:0007062 2 0.029
positive regulation of stem cell proliferation GO:2000648 1 0.029
cognition GO:0050890 1 0.029
regulation of rna biosynthetic process GO:2001141 213 0.029
Human Worm
apoptotic process GO:0006915 116 0.028
regulation of cell activation GO:0050865 1 0.028
negative regulation of developmental process GO:0051093 65 0.028
lamellipodium organization GO:0097581 1 0.028
regulation of chromosome segregation GO:0051983 1 0.028
regulation of synapse organization GO:0050807 3 0.028
brain development GO:0007420 293 0.028
negative regulation of dna metabolic process GO:0051053 4 0.028
meiosis i GO:0007127 1 0.027
maintenance of location GO:0051235 4 0.027
protein import into nucleus GO:0006606 3 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
Human Worm
negative regulation of biological process GO:0048519 304 0.027
gastrulation GO:0007369 208 0.027
regulation of catalytic activity GO:0050790 55 0.026
Human Zebrafish Mouse Worm
single organism reproductive process GO:0044702 40 0.026
alternative mrna splicing via spliceosome GO:0000380 1 0.026
forebrain development GO:0030900 96 0.026
epidermis development GO:0008544 48 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
Human Worm
protein targeting to nucleus GO:0044744 3 0.026
multicellular organism reproduction GO:0032504 35 0.026
Worm
g2 dna damage checkpoint GO:0031572 3 0.025
negative regulation of signal transduction GO:0009968 94 0.025
organelle fission GO:0048285 23 0.025
regulation of cell proliferation GO:0042127 37 0.025
regulation of cell cycle process GO:0010564 20 0.025
negative regulation of cellular process GO:0048523 283 0.025
cell fate commitment GO:0045165 99 0.025
regulation of cell shape GO:0008360 1 0.025
mitotic dna damage checkpoint GO:0044773 4 0.025
mesenchyme development GO:0060485 127 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
Human Worm
positive regulation of cell communication GO:0010647 56 0.025
Zebrafish Mouse Worm
regulation of cell differentiation GO:0045595 142 0.025
rna biosynthetic process GO:0032774 181 0.024
Human Worm
neuron projection development GO:0031175 180 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
negative regulation of metabolic process GO:0009892 86 0.024
regulation of biosynthetic process GO:0009889 250 0.024
Human Mouse Worm
phagocytosis GO:0006909 3 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
mitotic cell cycle process GO:1903047 48 0.024
neural tube patterning GO:0021532 33 0.023
protein metabolic process GO:0019538 183 0.023
Human Zebrafish Mouse Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
positive regulation of jnk cascade GO:0046330 3 0.023
Zebrafish
cell projection morphogenesis GO:0048858 244 0.023
cellular amine metabolic process GO:0044106 2 0.023
cellular response to chemical stimulus GO:0070887 157 0.022
regulation of molecular function GO:0065009 70 0.022
Human Zebrafish Mouse Worm
cellular response to dna damage stimulus GO:0006974 24 0.022
germ cell development GO:0007281 22 0.022
muscle cell differentiation GO:0042692 139 0.022
mononuclear cell proliferation GO:0032943 1 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
muscle organ development GO:0007517 101 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
Human Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
Human Worm
nucleic acid templated transcription GO:0097659 181 0.021
Human Worm
b cell activation GO:0042113 2 0.021
inner ear development GO:0048839 126 0.021
cellular response to external stimulus GO:0071496 2 0.021
cell part morphogenesis GO:0032990 246 0.021
transcription dna templated GO:0006351 181 0.021
Human Worm
lipid storage GO:0019915 1 0.021
rna metabolic process GO:0016070 219 0.021
Human Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.021
eye development GO:0001654 277 0.020
meiotic chromosome segregation GO:0045132 3 0.020
autophagy GO:0006914 4 0.020
negative regulation of defense response GO:0031348 2 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
positive regulation of developmental process GO:0051094 50 0.020
protein stabilization GO:0050821 2 0.020
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
Human Mouse Worm
anterior posterior pattern specification GO:0009952 152 0.020
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.020
cellular protein metabolic process GO:0044267 129 0.020
Human Zebrafish Mouse Worm
amine metabolic process GO:0009308 2 0.020
programmed cell death GO:0012501 119 0.020
neuromuscular synaptic transmission GO:0007274 2 0.020
cellular response to hormone stimulus GO:0032870 39 0.020
regulation of signaling GO:0023051 235 0.020
Zebrafish Mouse Worm
positive regulation of neural precursor cell proliferation GO:2000179 1 0.019
actin filament polymerization GO:0030041 2 0.019
skeletal muscle organ development GO:0060538 78 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
Human Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
negative regulation of dna replication GO:0008156 2 0.019
regulation of binding GO:0051098 3 0.019
neuron projection morphogenesis GO:0048812 161 0.019
sexual reproduction GO:0019953 36 0.018
skin development GO:0043588 54 0.018
cellular response to nutrient levels GO:0031669 2 0.018
mitotic cell cycle phase transition GO:0044772 9 0.018
negative regulation of signaling GO:0023057 96 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
transport GO:0006810 220 0.018
central nervous system neuron differentiation GO:0021953 74 0.018
posttranscriptional regulation of gene expression GO:0010608 14 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
heterocycle metabolic process GO:0046483 290 0.018
Human Worm
segmentation GO:0035282 97 0.018
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
wnt signaling pathway GO:0016055 80 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
neurotransmitter transport GO:0006836 2 0.018
b cell differentiation GO:0030183 1 0.018
epithelial cell differentiation GO:0030855 116 0.017
cellular response to starvation GO:0009267 1 0.017
embryonic limb morphogenesis GO:0030326 2 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of mrna processing GO:0050684 3 0.017
somite development GO:0061053 96 0.017
Zebrafish
regulation of response to cytokine stimulus GO:0060759 3 0.017
rna processing GO:0006396 25 0.017
forebrain regionalization GO:0021871 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
Human Worm
leukocyte proliferation GO:0070661 1 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
negative regulation of cell cycle process GO:0010948 9 0.017
regulation of establishment of planar polarity GO:0090175 4 0.017
gamete generation GO:0007276 33 0.017
negative regulation of cell differentiation GO:0045596 46 0.017
ameboidal type cell migration GO:0001667 143 0.017
immune system development GO:0002520 191 0.016
regulation of protein polymerization GO:0032271 2 0.016
membrane invagination GO:0010324 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
Human Worm
spindle assembly GO:0051225 2 0.016
dorsal ventral axis specification GO:0009950 14 0.016
rostrocaudal neural tube patterning GO:0021903 29 0.016
chemotaxis GO:0006935 104 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
response to drug GO:0042493 3 0.016
regulation of reproductive process GO:2000241 4 0.016
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
regulation of programmed cell death GO:0043067 101 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
phosphorus metabolic process GO:0006793 109 0.016
Human Zebrafish Mouse Worm
phagocytosis engulfment GO:0006911 1 0.016
single organism localization GO:1902578 225 0.016
regulation of mitotic cell cycle phase transition GO:1901990 8 0.016
regulation of protein targeting GO:1903533 2 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
Human Worm
blood vessel morphogenesis GO:0048514 216 0.016
response to external biotic stimulus GO:0043207 97 0.016
Worm
actin cytoskeleton organization GO:0030036 63 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
cell morphogenesis GO:0000902 289 0.015
macroautophagy GO:0016236 1 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Human Zebrafish Mouse Worm
tube morphogenesis GO:0035239 349 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
establishment of localization GO:0051234 244 0.015
cell proliferation in forebrain GO:0021846 3 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
striated muscle tissue development GO:0014706 110 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
regulation of developmental growth GO:0048638 38 0.015
organonitrogen compound metabolic process GO:1901564 74 0.014
lymphocyte proliferation GO:0046651 1 0.014
response to other organism GO:0051707 97 0.014
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
oocyte maturation GO:0001556 4 0.014
taxis GO:0042330 109 0.014
cellular ketone metabolic process GO:0042180 11 0.014
rna localization GO:0006403 4 0.014
determination of bilateral symmetry GO:0009855 204 0.014
Zebrafish
neural crest cell differentiation GO:0014033 72 0.014
determination of left right symmetry GO:0007368 179 0.014
homeostatic process GO:0042592 142 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
oxoacid metabolic process GO:0043436 31 0.014
neurotransmitter secretion GO:0007269 2 0.014
cardiac cell fate commitment GO:0060911 1 0.014
death GO:0016265 121 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
Human Zebrafish Mouse Worm
mesenchymal cell proliferation GO:0010463 1 0.014
spermatid development GO:0007286 2 0.014
somatic muscle development GO:0007525 4 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.013
regulation of organelle assembly GO:1902115 4 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
Human Zebrafish Mouse Worm
macromolecule modification GO:0043412 111 0.013
Human Zebrafish Mouse Worm
urogenital system development GO:0001655 97 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
adult behavior GO:0030534 2 0.013
peptide metabolic process GO:0006518 1 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.013
regulation of cell death GO:0010941 103 0.013
cellular amide metabolic process GO:0043603 4 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
hemopoiesis GO:0030097 183 0.013
neural tube development GO:0021915 62 0.013
response to biotic stimulus GO:0009607 97 0.013
Worm
regulation of organelle organization GO:0033043 29 0.013
cell fate specification GO:0001708 68 0.013
positive regulation of transport GO:0051050 2 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
sensory perception of touch GO:0050975 2 0.012
sensory organ morphogenesis GO:0090596 200 0.012
single organism biosynthetic process GO:0044711 71 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of apoptotic process GO:0042981 98 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
forebrain cell migration GO:0021885 1 0.012
regulation of growth GO:0040008 42 0.012
vasculature development GO:0001944 278 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
nucleus organization GO:0006997 7 0.012
neuron projection guidance GO:0097485 86 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Human Zebrafish Mouse Worm
organic acid metabolic process GO:0006082 31 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
lateral inhibition GO:0046331 1 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
dna templated transcription initiation GO:0006352 1 0.012
cellular component disassembly GO:0022411 1 0.012
multicellular organismal reproductive process GO:0048609 35 0.011
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
chemosensory behavior GO:0007635 1 0.011
dna catabolic process GO:0006308 1 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
blood vessel development GO:0001568 246 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
Human Worm
positive regulation of response to stimulus GO:0048584 80 0.011
Zebrafish Mouse Worm
female gamete generation GO:0007292 14 0.011
cell division GO:0051301 20 0.011
heart morphogenesis GO:0003007 156 0.011
reproductive process GO:0022414 40 0.011
Worm
muscle tissue development GO:0060537 110 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
regulation of protein metabolic process GO:0051246 56 0.011
Human Zebrafish Mouse Worm
activation of mapk activity GO:0000187 3 0.011
Zebrafish Mouse Worm
somatic stem cell maintenance GO:0035019 1 0.011
response to carbohydrate GO:0009743 3 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
regulation of cell cycle phase transition GO:1901987 8 0.011
negative regulation of gene expression GO:0010629 65 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
ear morphogenesis GO:0042471 64 0.011
tissue remodeling GO:0048771 4 0.011
negative regulation of cell cycle phase transition GO:1901988 5 0.011
small molecule metabolic process GO:0044281 77 0.011
digestive system development GO:0055123 289 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
female sex differentiation GO:0046660 4 0.011
dna metabolic process GO:0006259 27 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
hepaticobiliary system development GO:0061008 98 0.011
regulation of embryonic development GO:0045995 47 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
cell cycle phase transition GO:0044770 9 0.010
response to steroid hormone GO:0048545 35 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
negative regulation of cell communication GO:0010648 96 0.010
nuclear division GO:0000280 23 0.010
detection of mechanical stimulus involved in sensory perception of touch GO:0050976 2 0.010
megakaryocyte differentiation GO:0030219 1 0.010
female gonad development GO:0008585 4 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
axis specification GO:0009798 43 0.010
rna polyadenylation GO:0043631 2 0.010
startle response GO:0001964 4 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010

map2k6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031