Danio rerio

19 known processes

pcsk5a

proprotein convertase subtilisin/kexin type 5a

(Aliases: pc5.1,si:dkey-267i17.1,pcsk5/6a,pcsk5.1)

pcsk5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuromast development GO:0048884 46 0.997
mechanosensory lateral line system development GO:0048881 49 0.985
sensory organ development GO:0007423 393 0.984
lateral line system development GO:0048925 76 0.901
lateral line development GO:0048882 66 0.781
determination of bilateral symmetry GO:0009855 204 0.746
sensory system development GO:0048880 76 0.737
peptide metabolic process GO:0006518 1 0.670
chordate embryonic development GO:0043009 271 0.649
Zebrafish
anterior lateral line system development GO:0048898 9 0.607
embryonic skeletal system morphogenesis GO:0048704 93 0.559
Zebrafish
inner ear development GO:0048839 126 0.556
regulation of response to stimulus GO:0048583 269 0.410
embryonic organ development GO:0048568 381 0.339
Zebrafish
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.332
cellular nitrogen compound metabolic process GO:0034641 290 0.307
appendage morphogenesis GO:0035107 56 0.307
Zebrafish
stem cell proliferation GO:0072089 4 0.266
regulation of biological quality GO:0065008 263 0.253
female sex differentiation GO:0046660 4 0.246
defense response GO:0006952 47 0.227
embryonic skeletal system development GO:0048706 97 0.226
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.219
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.213
Zebrafish
innate immune response GO:0045087 13 0.199
regulation of epithelial cell proliferation GO:0050678 3 0.184
regulation of gene expression GO:0010468 265 0.171
multi organism cellular process GO:0044764 2 0.165
liver development GO:0001889 96 0.161
posterior lateral line system development GO:0048915 46 0.151
kidney epithelium development GO:0072073 23 0.149
urogenital system development GO:0001655 97 0.142
posterior lateral line neuromast development GO:0048919 20 0.139
regulation of multicellular organismal process GO:0051239 277 0.135
cartilage morphogenesis GO:0060536 13 0.135
Zebrafish
heart development GO:0007507 313 0.134
posterior lateral line development GO:0048916 38 0.130
neuromuscular process controlling balance GO:0050885 3 0.129
organelle organization GO:0006996 227 0.129
otolith development GO:0048840 32 0.126
hepaticobiliary system development GO:0061008 98 0.123
cellular ketone metabolic process GO:0042180 11 0.123
mitochondrion organization GO:0007005 4 0.122
ear development GO:0043583 127 0.121
dicarboxylic acid transport GO:0006835 1 0.121
cellular amide metabolic process GO:0043603 4 0.115
epithelial cell differentiation GO:0030855 116 0.115
regulation of transmembrane transporter activity GO:0022898 2 0.110
protein processing GO:0016485 12 0.109
membrane fusion GO:0061025 2 0.109
regulation of nitrogen compound metabolic process GO:0051171 251 0.107
ion transmembrane transport GO:0034220 91 0.105
cytokine mediated signaling pathway GO:0019221 7 0.105
organic substance biosynthetic process GO:1901576 289 0.100
cellular response to topologically incorrect protein GO:0035967 2 0.100
establishment of localization GO:0051234 244 0.098
determination of left right symmetry GO:0007368 179 0.098
embryo development ending in birth or egg hatching GO:0009792 271 0.098
Zebrafish
response to corticosteroid GO:0031960 1 0.096
myotome development GO:0061055 1 0.095
regulation of stem cell proliferation GO:0072091 2 0.094
aging GO:0007568 2 0.094
response to dexamethasone GO:0071548 1 0.093
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.093
cellular macromolecule metabolic process GO:0044260 391 0.093
ear morphogenesis GO:0042471 64 0.090
cell death in response to oxidative stress GO:0036473 2 0.090
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.089
multicellular organism growth GO:0035264 4 0.087
membrane repolarization GO:0086009 2 0.085
membrane organization GO:0061024 21 0.084
negative regulation of reproductive process GO:2000242 3 0.082
cation transmembrane transport GO:0098655 65 0.077
negative regulation of biological process GO:0048519 304 0.077
negative regulation of multicellular organismal process GO:0051241 69 0.076
regulation of vitamin metabolic process GO:0030656 6 0.075
central nervous system development GO:0007417 387 0.075
melanin metabolic process GO:0006582 2 0.074
striated muscle cell development GO:0055002 108 0.073
developmental programmed cell death GO:0010623 4 0.073
detection of mechanical stimulus GO:0050982 11 0.072
specification of symmetry GO:0009799 204 0.072
anterior lateral line development GO:0048899 5 0.071
modification of morphology or physiology of other organism GO:0035821 4 0.070
endoplasmic reticulum unfolded protein response GO:0030968 2 0.065
nitrogen compound metabolic process GO:0006807 319 0.063
single organism localization GO:1902578 225 0.062
response to alkaloid GO:0043279 2 0.062
cellular amine metabolic process GO:0044106 2 0.062
carboxylic acid metabolic process GO:0019752 22 0.061
striated muscle cell differentiation GO:0051146 129 0.060
blood vessel endothelial cell migration GO:0043534 18 0.059
locomotion GO:0040011 313 0.059
homeostatic process GO:0042592 142 0.058
regulation of cellular ketone metabolic process GO:0010565 7 0.058
regulation of developmental process GO:0050793 247 0.058
organonitrogen compound metabolic process GO:1901564 74 0.058
regulation of membrane repolarization GO:0060306 1 0.058
glial cell migration GO:0008347 3 0.057
biosynthetic process GO:0009058 294 0.056
immune system process GO:0002376 241 0.056
connective tissue development GO:0061448 99 0.056
Zebrafish
notch signaling pathway GO:0007219 35 0.055
sensory organ morphogenesis GO:0090596 200 0.055
epithelial cell development GO:0002064 42 0.055
response to drug GO:0042493 3 0.054
negative regulation of cellular process GO:0048523 283 0.054
amide biosynthetic process GO:0043604 1 0.054
nephron epithelium morphogenesis GO:0072088 1 0.053
retina development in camera type eye GO:0060041 146 0.052
determination of heart left right asymmetry GO:0061371 117 0.052
signal transduction GO:0007165 455 0.051
regulation of rna metabolic process GO:0051252 224 0.051
nucleic acid templated transcription GO:0097659 181 0.051
nucleobase containing compound metabolic process GO:0006139 274 0.051
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.051
neuron development GO:0048666 262 0.051
fluid transport GO:0042044 17 0.050
cellular response to lipopolysaccharide GO:0071222 3 0.050
hatching GO:0035188 4 0.050
transport GO:0006810 220 0.050
negative regulation of cell death GO:0060548 60 0.049
cellular pigmentation GO:0033059 30 0.049
muscle cell migration GO:0014812 4 0.049
heterocycle metabolic process GO:0046483 290 0.049
cilium organization GO:0044782 71 0.048
protein metabolic process GO:0019538 183 0.048
regulation of response to cytokine stimulus GO:0060759 3 0.048
cellular biosynthetic process GO:0044249 286 0.047
regulation of jak stat cascade GO:0046425 3 0.047
regulation of ion transmembrane transporter activity GO:0032412 2 0.047
regionalization GO:0003002 274 0.047
positive regulation of macromolecule metabolic process GO:0010604 93 0.046
regulation of cell development GO:0060284 100 0.046
regulation of notch signaling pathway GO:0008593 16 0.045
innervation GO:0060384 3 0.045
equilibrioception GO:0050957 2 0.045
cellular response to organic substance GO:0071310 105 0.044
adult behavior GO:0030534 2 0.044
neuron differentiation GO:0030182 353 0.044
organic acid metabolic process GO:0006082 31 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
cellular component movement GO:0006928 335 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.042
myotube differentiation GO:0014902 45 0.041
gland development GO:0048732 143 0.041
cellular response to chemical stimulus GO:0070887 157 0.041
negative regulation of response to stimulus GO:0048585 104 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
positive regulation of innate immune response GO:0045089 8 0.040
single organism membrane fusion GO:0044801 2 0.040
phosphate containing compound metabolic process GO:0006796 108 0.040
negative regulation of protein phosphorylation GO:0001933 4 0.039
dorsal ventral pattern formation GO:0009953 125 0.039
negative regulation of peptidase activity GO:0010466 10 0.039
positive regulation of cellular amine metabolic process GO:0033240 0 0.039
response to glucocorticoid GO:0051384 1 0.039
system process GO:0003008 185 0.039
organonitrogen compound biosynthetic process GO:1901566 47 0.038
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.038
carbohydrate homeostasis GO:0033500 1 0.038
eye development GO:0001654 277 0.038
negative regulation of mitosis GO:0045839 3 0.037
positive regulation of catabolic process GO:0009896 4 0.037
primitive erythrocyte differentiation GO:0060319 5 0.037
epithelium migration GO:0090132 25 0.037
cellular localization GO:0051641 97 0.037
negative regulation of epithelial cell proliferation GO:0050680 1 0.036
cellular component assembly involved in morphogenesis GO:0010927 107 0.035
generation of neurons GO:0048699 385 0.035
negative regulation of signal transduction GO:0009968 94 0.035
phagocytosis GO:0006909 3 0.035
response to organic substance GO:0010033 153 0.035
peptidyl serine modification GO:0018209 2 0.034
cellular response to unfolded protein GO:0034620 2 0.034
organism emergence from protective structure GO:0071684 4 0.034
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.034
response to topologically incorrect protein GO:0035966 2 0.034
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.033
response to unfolded protein GO:0006986 2 0.033
fin morphogenesis GO:0033334 53 0.033
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.033
membrane invagination GO:0010324 1 0.033
negative regulation of metabolic process GO:0009892 86 0.033
camera type eye development GO:0043010 222 0.033
erythrocyte differentiation GO:0030218 54 0.033
cellular response to extracellular stimulus GO:0031668 2 0.032
protein dephosphorylation GO:0006470 3 0.031
cellular response to lipid GO:0071396 39 0.031
renal tubule morphogenesis GO:0061333 1 0.031
calcium mediated signaling GO:0019722 2 0.031
response to ketone GO:1901654 1 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
positive regulation of embryonic development GO:0040019 3 0.030
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.030
skeletal system morphogenesis GO:0048705 102 0.030
Zebrafish
fat soluble vitamin metabolic process GO:0006775 4 0.030
regulation of binding GO:0051098 3 0.030
ovulation cycle process GO:0022602 2 0.030
female gonad development GO:0008585 4 0.030
hormone transport GO:0009914 2 0.030
regulation of cellular metabolic process GO:0031323 320 0.029
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.029
peripheral nervous system development GO:0007422 55 0.029
regulation of cell substrate adhesion GO:0010810 1 0.029
larval behavior GO:0030537 5 0.029
regulation of signal transduction GO:0009966 225 0.029
development of primary female sexual characteristics GO:0046545 4 0.029
cell part morphogenesis GO:0032990 246 0.028
response to steroid hormone GO:0048545 35 0.028
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.028
regulation of reproductive process GO:2000241 4 0.028
synaptic target recognition GO:0008039 1 0.028
single organism transport GO:0044765 206 0.028
regulation of cellular ph reduction GO:0032847 1 0.028
regulation of cell communication GO:0010646 232 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.027
single organism organelle organization GO:1902589 199 0.027
actin filament based process GO:0030029 64 0.027
cellular carbohydrate metabolic process GO:0044262 4 0.027
mitochondrial transport GO:0006839 2 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
reproduction GO:0000003 40 0.027
oxoacid metabolic process GO:0043436 31 0.027
regulation of protein phosphorylation GO:0001932 18 0.027
viral process GO:0016032 1 0.027
regulation of molecular function GO:0065009 70 0.026
epithelial cell proliferation GO:0050673 17 0.026
homeostasis of number of cells GO:0048872 62 0.026
response to amino acid GO:0043200 2 0.026
calcium ion import GO:0070509 4 0.026
inner ear morphogenesis GO:0042472 63 0.026
regulation of transporter activity GO:0032409 2 0.026
atp catabolic process GO:0006200 4 0.026
regulation of phosphorus metabolic process GO:0051174 43 0.026
cell cell signaling GO:0007267 52 0.025
localization of cell GO:0051674 244 0.025
proteolysis GO:0006508 38 0.025
response to uv GO:0009411 3 0.025
nephron tubule morphogenesis GO:0072078 1 0.025
regulation of peptidase activity GO:0052547 23 0.025
small molecule metabolic process GO:0044281 77 0.025
inorganic ion transmembrane transport GO:0098660 57 0.025
transmembrane transport GO:0055085 120 0.025
positive regulation of transport GO:0051050 2 0.025
regulation of retina development in camera type eye GO:1902866 2 0.025
lymph vessel development GO:0001945 27 0.025
regulation of metabolic process GO:0019222 359 0.024
mesenchyme development GO:0060485 127 0.024
anatomical structure homeostasis GO:0060249 36 0.024
interspecies interaction between organisms GO:0044419 4 0.024
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.023
programmed cell death GO:0012501 119 0.023
pigment metabolic process GO:0042440 12 0.023
organelle fusion GO:0048284 3 0.023
regulation of behavior GO:0050795 24 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
secondary metabolic process GO:0019748 3 0.023
heart contraction GO:0060047 71 0.023
forebrain development GO:0030900 96 0.023
rna biosynthetic process GO:0032774 181 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
phosphorus metabolic process GO:0006793 109 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.022
negative regulation of cell communication GO:0010648 96 0.022
nik nf kappab signaling GO:0038061 1 0.022
cytoskeleton organization GO:0007010 96 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
regulation of neural retina development GO:0061074 2 0.022
actin filament based movement GO:0030048 1 0.022
skeletal muscle organ development GO:0060538 78 0.022
organic substance catabolic process GO:1901575 28 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.022
er nucleus signaling pathway GO:0006984 2 0.022
response to chemical GO:0042221 320 0.021
inorganic cation transmembrane transport GO:0098662 50 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.021
zymogen activation GO:0031638 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
response to bacterium GO:0009617 58 0.021
single organism metabolic process GO:0044710 217 0.021
multicellular organismal response to stress GO:0033555 2 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
hormone secretion GO:0046879 2 0.020
regulation of neurogenesis GO:0050767 87 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
transcription dna templated GO:0006351 181 0.020
regulation of system process GO:0044057 40 0.020
positive regulation of notch signaling pathway GO:0045747 3 0.020
regulation of cellular ph GO:0030641 1 0.020
tyrosine phosphorylation of stat protein GO:0007260 1 0.020
myeloid cell differentiation GO:0030099 86 0.020
regulation of locomotion GO:0040012 55 0.020
single organism membrane organization GO:0044802 20 0.019
neuron cellular homeostasis GO:0070050 3 0.019
regulation of neuron differentiation GO:0045664 56 0.019
neuromast deposition GO:0048885 9 0.019
macromolecular complex disassembly GO:0032984 1 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
response to hormone GO:0009725 48 0.019
lipid metabolic process GO:0006629 52 0.019
hair cell differentiation GO:0035315 32 0.019
regulation of biosynthetic process GO:0009889 250 0.019
response to carbohydrate GO:0009743 3 0.019
regulation of programmed cell death GO:0043067 101 0.019
diencephalon development GO:0021536 58 0.019
negative regulation of nucleic acid templated transcription GO:1903507 45 0.019
ovarian follicle development GO:0001541 2 0.019
homeostasis of number of cells within a tissue GO:0048873 4 0.019
cytokinesis GO:0000910 3 0.019
primitive hemopoiesis GO:0060215 27 0.019
cellular response to stress GO:0033554 62 0.019
apoptotic process involved in development GO:1902742 2 0.019
cell cycle g2 m phase transition GO:0044839 4 0.019
regulation of metal ion transport GO:0010959 4 0.019
cellular cation homeostasis GO:0030003 17 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
gliogenesis GO:0042063 45 0.018
regulation of calcium ion transport GO:0051924 2 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
response to external stimulus GO:0009605 264 0.018
cilium morphogenesis GO:0060271 85 0.018
cellular component disassembly GO:0022411 1 0.018
apoptotic process involved in morphogenesis GO:0060561 2 0.018
somatic stem cell maintenance GO:0035019 1 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
mitotic cell cycle process GO:1903047 48 0.018
skin development GO:0043588 54 0.018
skeletal system development GO:0001501 181 0.018
Zebrafish
positive regulation of lipase activity GO:0060193 1 0.018
regulation of phosphate metabolic process GO:0019220 43 0.018
golgi vesicle transport GO:0048193 3 0.017
leukocyte migration GO:0050900 15 0.017
negative regulation of behavior GO:0048521 6 0.017
positive regulation of epithelial cell proliferation GO:0050679 1 0.017
ovulation cycle GO:0042698 2 0.017
retinal cell programmed cell death GO:0046666 2 0.017
otic vesicle development GO:0071599 42 0.017
cell proliferation involved in heart morphogenesis GO:0061323 2 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
response to cytokine GO:0034097 7 0.017
muscle cell development GO:0055001 115 0.017
regulation of collagen metabolic process GO:0010712 2 0.016
regulation of circadian rhythm GO:0042752 4 0.016
carboxylic acid transport GO:0046942 8 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.016
leukocyte chemotaxis GO:0030595 12 0.016
endosomal transport GO:0016197 2 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
renal system development GO:0072001 94 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
amine metabolic process GO:0009308 2 0.016
regulation of membrane potential GO:0042391 23 0.016
camera type eye morphogenesis GO:0048593 108 0.016
pectoral fin morphogenesis GO:0035138 29 0.016
multi organism process GO:0051704 134 0.016
canonical wnt signaling pathway GO:0060070 48 0.016
regulation of cell death GO:0010941 103 0.016
regulation of cysteine type endopeptidase activity GO:2000116 21 0.016
larval development GO:0002164 2 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
sodium ion transmembrane transport GO:0035725 21 0.016
protein maturation GO:0051604 12 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
amino acid transport GO:0006865 2 0.015
axon development GO:0061564 166 0.015
gtp metabolic process GO:0046039 4 0.015
nephron morphogenesis GO:0072028 2 0.015
sexual reproduction GO:0019953 36 0.015
regulation of cellular response to oxidative stress GO:1900407 2 0.015
regulation of cell shape GO:0008360 1 0.015
negative regulation of developmental process GO:0051093 65 0.015
erythrocyte homeostasis GO:0034101 55 0.015
phagocytosis engulfment GO:0006911 1 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.015
catabolic process GO:0009056 32 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of cytokine mediated signaling pathway GO:0001959 3 0.015
metal ion transport GO:0030001 58 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
startle response GO:0001964 4 0.015
adherens junction organization GO:0034332 4 0.015
organic acid transport GO:0015849 9 0.015
regulation of ph GO:0006885 3 0.014
granulocyte migration GO:0097530 11 0.014
regulation of glial cell proliferation GO:0060251 4 0.014
cell proliferation GO:0008283 80 0.014
posterior lateral line neuromast deposition GO:0048922 5 0.014
heart morphogenesis GO:0003007 156 0.014
gtp catabolic process GO:0006184 2 0.014
lipid storage GO:0019915 1 0.014
response to stress GO:0006950 263 0.014
negative regulation of multi organism process GO:0043901 3 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
rna metabolic process GO:0016070 219 0.014
vasculogenesis GO:0001570 41 0.014
cell death GO:0008219 121 0.014
cartilage development GO:0051216 96 0.014
Zebrafish
reactive oxygen species metabolic process GO:0072593 6 0.014
response to lipid GO:0033993 60 0.014
regulation of protein complex assembly GO:0043254 3 0.014
negative regulation of signaling GO:0023057 96 0.014
ribonucleotide metabolic process GO:0009259 27 0.014
otic vesicle formation GO:0030916 27 0.014
apoptotic process GO:0006915 116 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
brain development GO:0007420 293 0.013
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.013
negative regulation of cell differentiation GO:0045596 46 0.013
mitotic nuclear division GO:0007067 18 0.013
regulation of primary metabolic process GO:0080090 311 0.013
regulation of myotube differentiation GO:0010830 2 0.013
eye morphogenesis GO:0048592 144 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of nik nf kappab signaling GO:1901222 1 0.013
organelle membrane fusion GO:0090174 2 0.013
protein complex disassembly GO:0043241 1 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
hormone metabolic process GO:0042445 19 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
regulation of inner ear receptor cell differentiation GO:2000980 1 0.013
action potential GO:0001508 19 0.013
regulation of signaling GO:0023051 235 0.013
response to oxygen radical GO:0000305 2 0.013
negative regulation of translation GO:0017148 1 0.013
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.013
regulation of immune system process GO:0002682 34 0.013
granulocyte chemotaxis GO:0071621 11 0.013
metal ion homeostasis GO:0055065 26 0.013
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.013
head development GO:0060322 303 0.013
regulation of oxidative stress induced cell death GO:1903201 2 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
positive regulation of gliogenesis GO:0014015 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.012
response to inorganic substance GO:0010035 38 0.012
ion transport GO:0006811 114 0.012
cellular component assembly GO:0022607 170 0.012
muscle cell differentiation GO:0042692 139 0.012
neuroblast proliferation GO:0007405 2 0.012
activation of mapk activity GO:0000187 3 0.012
cellular metal ion homeostasis GO:0006875 16 0.012
anion transport GO:0006820 38 0.012
negative regulation of gene expression GO:0010629 65 0.012
nucleotide metabolic process GO:0009117 28 0.012
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.012
cell morphogenesis GO:0000902 289 0.012
cellular component morphogenesis GO:0032989 336 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
stem cell division GO:0017145 1 0.012
cellular component biogenesis GO:0044085 178 0.012
protein targeting to nucleus GO:0044744 3 0.012
response to oxygen containing compound GO:1901700 55 0.012
hemopoiesis GO:0030097 183 0.012
lipid digestion GO:0044241 3 0.012
multicellular organismal signaling GO:0035637 22 0.012
regulation of intracellular ph GO:0051453 1 0.012
regulation of protein metabolic process GO:0051246 56 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
pharyngeal muscle development GO:0043282 4 0.011
immune system development GO:0002520 191 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of protein binding GO:0043393 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
glial cell proliferation GO:0014009 4 0.011
radial glial cell differentiation GO:0060019 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
modification by symbiont of host morphology or physiology GO:0044003 4 0.011

pcsk5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.491
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.491
nonsyndromic deafness DOID:0050563 0 0.491
sensory system disease DOID:0050155 0 0.491
disease of anatomical entity DOID:7 0 0.491
nervous system disease DOID:863 0 0.491
immune system disease DOID:2914 0 0.064
hematopoietic system disease DOID:74 0 0.064
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
eye and adnexa disease DOID:1492 0 0.016