Danio rerio

0 known processes

irbp

interphotoreceptor retinoid-binding protein

irbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.496
sensory organ morphogenesis GO:0090596 200 0.389
localization of cell GO:0051674 244 0.379
phototransduction GO:0007602 2 0.347
neuron differentiation GO:0030182 353 0.302
absorption of visible light GO:0016038 2 0.300
light absorption GO:0016037 2 0.288
regulation of metabolic process GO:0019222 359 0.245
cellular component movement GO:0006928 335 0.233
neuron development GO:0048666 262 0.192
phototransduction visible light GO:0007603 2 0.191
eye development GO:0001654 277 0.190
detection of abiotic stimulus GO:0009582 24 0.190
cell motility GO:0048870 244 0.187
detection of visible light GO:0009584 12 0.171
cell surface receptor signaling pathway GO:0007166 325 0.171
eye morphogenesis GO:0048592 144 0.168
neuron projection development GO:0031175 180 0.165
g protein coupled receptor signaling pathway GO:0007186 74 0.161
response to chemical GO:0042221 320 0.158
sensory perception of chemical stimulus GO:0007606 3 0.156
detection of stimulus GO:0051606 29 0.154
detection of external stimulus GO:0009581 24 0.150
maintenance of location GO:0051235 4 0.143
angiogenesis GO:0001525 158 0.139
digestive tract development GO:0048565 265 0.137
regulation of sequestering of calcium ion GO:0051282 4 0.135
eye photoreceptor cell differentiation GO:0001754 45 0.119
visual perception GO:0007601 17 0.118
detection of light stimulus GO:0009583 12 0.118
locomotion GO:0040011 313 0.117
gastrulation GO:0007369 208 0.117
oxoacid metabolic process GO:0043436 31 0.116
regulation of biological quality GO:0065008 263 0.115
cellular amino acid metabolic process GO:0006520 7 0.112
positive regulation of map kinase activity GO:0043406 3 0.112
small molecule metabolic process GO:0044281 77 0.110
regulation of cell communication GO:0010646 232 0.109
gastrulation with mouth forming second GO:0001702 44 0.108
organic acid metabolic process GO:0006082 31 0.105
single organism metabolic process GO:0044710 217 0.105
nucleocytoplasmic transport GO:0006913 4 0.105
vasculature development GO:0001944 278 0.105
signal transduction GO:0007165 455 0.104
nuclear transport GO:0051169 4 0.102
digestive system development GO:0055123 289 0.102
blood vessel development GO:0001568 246 0.101
negative regulation of protein phosphorylation GO:0001933 4 0.099
chordate embryonic development GO:0043009 271 0.098
photoperiodism GO:0009648 11 0.097
convergent extension GO:0060026 118 0.093
blood vessel morphogenesis GO:0048514 216 0.093
digestive tract morphogenesis GO:0048546 231 0.092
stem cell proliferation GO:0072089 4 0.091
vitamin a biosynthetic process GO:0035238 1 0.089
ameboidal type cell migration GO:0001667 143 0.088
microtubule based process GO:0007017 60 0.084
response to wounding GO:0009611 116 0.084
photoreceptor cell differentiation GO:0046530 55 0.083
sequestering of metal ion GO:0051238 3 0.081
carboxylic acid metabolic process GO:0019752 22 0.079
epiboly GO:0090504 41 0.079
response to uv GO:0009411 3 0.079
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.078
establishment of organelle localization GO:0051656 45 0.076
cellular response to radiation GO:0071478 4 0.074
cell migration involved in gastrulation GO:0042074 79 0.073
sequestering of calcium ion GO:0051208 3 0.073
light induced release of internally sequestered calcium ion GO:0008377 1 0.072
organelle localization GO:0051640 49 0.072
negative regulation of protein kinase activity GO:0006469 4 0.071
regulation of localization GO:0032879 104 0.071
stem cell division GO:0017145 1 0.071
protein metabolic process GO:0019538 183 0.069
regulation of macromolecule metabolic process GO:0060255 317 0.068
negative regulation of sequestering of calcium ion GO:0051283 4 0.065
photoreceptor cell development GO:0042461 40 0.065
guanosine containing compound metabolic process GO:1901068 4 0.064
enzyme linked receptor protein signaling pathway GO:0007167 106 0.063
regulation of signaling GO:0023051 235 0.060
cell growth GO:0016049 57 0.058
gene expression GO:0010467 252 0.058
response to light stimulus GO:0009416 46 0.057
cellular response to light stimulus GO:0071482 4 0.057
organelle organization GO:0006996 227 0.056
cellular macromolecule metabolic process GO:0044260 391 0.056
rhodopsin mediated signaling pathway GO:0016056 1 0.055
regulation of circadian sleep wake cycle GO:0042749 1 0.055
transmission of nerve impulse GO:0019226 19 0.055
cellular response to chemical stimulus GO:0070887 157 0.055
tube morphogenesis GO:0035239 349 0.054
cellular protein metabolic process GO:0044267 129 0.054
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.054
behavior GO:0007610 74 0.053
vitamin a metabolic process GO:0006776 1 0.053
cellular lipid metabolic process GO:0044255 36 0.052
gtp catabolic process GO:0006184 2 0.049
regulation of gene expression GO:0010468 265 0.049
generation of neurons GO:0048699 385 0.049
single organism organelle organization GO:1902589 199 0.048
rhythmic process GO:0048511 21 0.048
regulation of nucleocytoplasmic transport GO:0046822 2 0.046
regulation of intracellular protein transport GO:0033157 3 0.045
neuron projection extension GO:1990138 45 0.044
protein targeting to nucleus GO:0044744 3 0.043
fat soluble vitamin metabolic process GO:0006775 4 0.043
sensory perception of light stimulus GO:0050953 19 0.043
establishment of protein localization to organelle GO:0072594 4 0.043
activation of mapk activity GO:0000187 3 0.042
taxis GO:0042330 109 0.042
cellular component assembly GO:0022607 170 0.042
nuclear export GO:0051168 1 0.042
lipid metabolic process GO:0006629 52 0.041
larval development GO:0002164 2 0.041
central nervous system development GO:0007417 387 0.041
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.041
cytokinesis GO:0000910 3 0.041
fat soluble vitamin biosynthetic process GO:0042362 2 0.041
single organism cellular localization GO:1902580 46 0.041
inositol lipid mediated signaling GO:0048017 2 0.040
nuclear import GO:0051170 3 0.038
cellular amine metabolic process GO:0044106 2 0.037
regulation of primary metabolic process GO:0080090 311 0.037
aging GO:0007568 2 0.035
embryo development ending in birth or egg hatching GO:0009792 271 0.035
regulation of fatty acid metabolic process GO:0019217 1 0.035
cell projection morphogenesis GO:0048858 244 0.035
negative regulation of kinase activity GO:0033673 4 0.035
establishment of blood brain barrier GO:0060856 2 0.034
amine metabolic process GO:0009308 2 0.034
developmental growth GO:0048589 166 0.034
transport GO:0006810 220 0.033
single organism localization GO:1902578 225 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
cell migration involved in heart development GO:0060973 22 0.033
growth GO:0040007 174 0.033
axon ensheathment in central nervous system GO:0032291 2 0.033
developmental programmed cell death GO:0010623 4 0.033
developmental growth involved in morphogenesis GO:0060560 86 0.033
establishment of cell polarity GO:0030010 18 0.032
retina development in camera type eye GO:0060041 146 0.031
regulation of protein transport GO:0051223 3 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
response to abiotic stimulus GO:0009628 122 0.031
neuron projection guidance GO:0097485 86 0.030
regulation of nucleotide catabolic process GO:0030811 2 0.030
regulation of neurogenesis GO:0050767 87 0.030
organonitrogen compound metabolic process GO:1901564 74 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
cellular response to organic substance GO:0071310 105 0.029
sensory organ development GO:0007423 393 0.028
cellular ketone metabolic process GO:0042180 11 0.028
cellular response to external stimulus GO:0071496 2 0.028
regulation of cytoplasmic transport GO:1903649 4 0.027
regulation of neuron projection development GO:0010975 40 0.027
guanosine containing compound catabolic process GO:1901069 2 0.026
wound healing GO:0042060 90 0.026
regulation of inflammatory response GO:0050727 2 0.026
lipid storage GO:0019915 1 0.026
convergent extension involved in gastrulation GO:0060027 71 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
embryonic heart tube development GO:0035050 133 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.026
cell migration GO:0016477 237 0.026
establishment of spindle localization GO:0051293 12 0.025
single organism transport GO:0044765 206 0.025
single organism behavior GO:0044708 24 0.024
camera type eye development GO:0043010 222 0.024
detection of stimulus involved in sensory perception GO:0050906 21 0.024
establishment of localization GO:0051234 244 0.024
regulation of protein binding GO:0043393 3 0.024
regulation of response to stimulus GO:0048583 269 0.024
protein modification process GO:0036211 100 0.024
positive regulation of biological process GO:0048518 253 0.023
gtp metabolic process GO:0046039 4 0.023
receptor recycling GO:0001881 4 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
l amino acid transport GO:0015807 1 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
locomotor rhythm GO:0045475 3 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
segmentation GO:0035282 97 0.022
regulation of cell projection organization GO:0031344 44 0.022
heart development GO:0007507 313 0.022
establishment of localization in cell GO:0051649 77 0.021
positive regulation of protein metabolic process GO:0051247 23 0.021
regeneration GO:0031099 91 0.021
homeostatic process GO:0042592 142 0.021
adult behavior GO:0030534 2 0.021
establishment of mitotic spindle localization GO:0040001 12 0.021
system process GO:0003008 185 0.021
chemotaxis GO:0006935 104 0.021
cellular aldehyde metabolic process GO:0006081 4 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
regulation of chemokine activity GO:1900136 3 0.020
neuroblast proliferation GO:0007405 2 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of cellular component movement GO:0051270 55 0.020
response to radiation GO:0009314 51 0.020
endoderm development GO:0007492 49 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
phagocytosis GO:0006909 3 0.020
positive regulation of cellular process GO:0048522 201 0.020
single organism nuclear import GO:1902593 3 0.019
cellular localization GO:0051641 97 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of gtpase activity GO:0043087 2 0.019
intracellular estrogen receptor signaling pathway GO:0030520 3 0.018
cytoskeleton organization GO:0007010 96 0.018
cell morphogenesis GO:0000902 289 0.018
somitogenesis GO:0001756 87 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
phosphorylation GO:0016310 69 0.018
response to stress GO:0006950 263 0.018
response to organic substance GO:0010033 153 0.018
cell projection organization GO:0030030 284 0.018
protein import GO:0017038 3 0.018
glial cell differentiation GO:0010001 42 0.018
regulation of locomotion GO:0040012 55 0.018
phosphorus metabolic process GO:0006793 109 0.017
neuron projection morphogenesis GO:0048812 161 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.017
regulation of cell differentiation GO:0045595 142 0.017
organic substance biosynthetic process GO:1901576 289 0.017
response to vitamin GO:0033273 3 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
axon development GO:0061564 166 0.016
calcium mediated signaling GO:0019722 2 0.016
membrane invagination GO:0010324 1 0.016
macromolecule modification GO:0043412 111 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
immune system process GO:0002376 241 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
tissue homeostasis GO:0001894 25 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
oxidation reduction process GO:0055114 41 0.016
phagocytosis engulfment GO:0006911 1 0.016
response to light intensity GO:0009642 1 0.016
regulation of response to external stimulus GO:0032101 31 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
establishment of mitotic spindle orientation GO:0000132 10 0.015
negative regulation of biological process GO:0048519 304 0.015
vesicle localization GO:0051648 27 0.015
regulation of protein metabolic process GO:0051246 56 0.015
positive regulation of transport GO:0051050 2 0.015
neuronal action potential GO:0019228 18 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
mitotic cell cycle process GO:1903047 48 0.015
vitamin biosynthetic process GO:0009110 2 0.015
cell fate commitment GO:0045165 99 0.015
protein localization to nucleus GO:0034504 3 0.015
cellular protein catabolic process GO:0044257 4 0.014
ras protein signal transduction GO:0007265 7 0.014
neurological system process GO:0050877 62 0.014
protein phosphorylation GO:0006468 47 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
endocrine process GO:0050886 2 0.014
synaptic vesicle localization GO:0097479 1 0.014
response to other organism GO:0051707 97 0.014
endothelial cell differentiation GO:0045446 20 0.014
pigmentation GO:0043473 85 0.014
appendage morphogenesis GO:0035107 56 0.014
regulation of cell motility GO:2000145 46 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
positive regulation of cell cycle GO:0045787 3 0.013
vitamin metabolic process GO:0006766 11 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
rna biosynthetic process GO:0032774 181 0.013
establishment of endothelial barrier GO:0061028 3 0.013
regulation of dna replication GO:0006275 3 0.013
camera type eye photoreceptor cell differentiation GO:0060219 19 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
regulation of cell migration GO:0030334 40 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
response to drug GO:0042493 3 0.013
sprouting angiogenesis GO:0002040 53 0.013
rho protein signal transduction GO:0007266 5 0.013
cyclic nucleotide metabolic process GO:0009187 18 0.013
neuron projection regeneration GO:0031102 16 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
cellular pigmentation GO:0033059 30 0.013
regulation of cellular component organization GO:0051128 86 0.013
fin regeneration GO:0031101 51 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of receptor recycling GO:0001919 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
sensory perception of smell GO:0007608 2 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
regulation of transcription dna templated GO:0006355 213 0.012
anion transport GO:0006820 38 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
retinoic acid receptor signaling pathway GO:0048384 16 0.012
multi organism process GO:0051704 134 0.012
biosynthetic process GO:0009058 294 0.012
spindle localization GO:0051653 12 0.012
regulation of organelle organization GO:0033043 29 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
multicellular organism growth GO:0035264 4 0.012
rna metabolic process GO:0016070 219 0.012
lipid biosynthetic process GO:0008610 22 0.012
regulation of cell cell adhesion GO:0022407 13 0.012
heterocycle biosynthetic process GO:0018130 215 0.011
regulation of signal transduction GO:0009966 225 0.011
protein desumoylation GO:0016926 1 0.011
protein modification by small protein removal GO:0070646 1 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
regulation of developmental process GO:0050793 247 0.011
positive regulation of signaling GO:0023056 56 0.011
multicellular organismal signaling GO:0035637 22 0.011
circadian rhythm GO:0007623 19 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of calcium ion transport GO:0051924 2 0.011
gliogenesis GO:0042063 45 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
detection of light stimulus involved in sensory perception GO:0050962 7 0.011
brain development GO:0007420 293 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
cellular protein modification process GO:0006464 100 0.011
protein localization GO:0008104 40 0.011
retinal metabolic process GO:0042574 3 0.011
single organism biosynthetic process GO:0044711 71 0.011
hemopoiesis GO:0030097 183 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
primary amino compound biosynthetic process GO:1901162 1 0.010
cellular biosynthetic process GO:0044249 286 0.010
embryonic organ development GO:0048568 381 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
glial cell development GO:0021782 20 0.010
response to monosaccharide GO:0034284 3 0.010
sensory perception GO:0007600 39 0.010

irbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.166
sensory system disease DOID:0050155 0 0.045
eye and adnexa disease DOID:1492 0 0.045
nervous system disease DOID:863 0 0.045
eye disease DOID:5614 0 0.028
retinal disease DOID:5679 0 0.020
retinal degeneration DOID:8466 0 0.020
retinitis pigmentosa DOID:10584 0 0.020
disease of metabolism DOID:0014667 0 0.018