Danio rerio

0 known processes

im:7147988

im:7147988

im:7147988 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.067
positive regulation of cellular component biogenesis GO:0044089 3 0.051
guanosine containing compound catabolic process GO:1901069 2 0.049
cell projection organization GO:0030030 284 0.048
guanosine containing compound metabolic process GO:1901068 4 0.044
gtp metabolic process GO:0046039 4 0.043
maintenance of location GO:0051235 4 0.042
cellular biosynthetic process GO:0044249 286 0.042
aging GO:0007568 2 0.041
signal transduction GO:0007165 455 0.040
response to drug GO:0042493 3 0.038
positive regulation of transport GO:0051050 2 0.037
establishment of protein localization to plasma membrane GO:0090002 1 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
gtp catabolic process GO:0006184 2 0.037
regulation of protein complex assembly GO:0043254 3 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.035
multicellular organism growth GO:0035264 4 0.035
regulation of multicellular organism growth GO:0040014 4 0.034
amine metabolic process GO:0009308 2 0.034
positive regulation of cell cycle GO:0045787 3 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
protein localization to plasma membrane GO:0072659 1 0.034
cellular macromolecule metabolic process GO:0044260 391 0.034
response to chemical GO:0042221 320 0.033
golgi vesicle transport GO:0048193 3 0.033
morphogenesis of an epithelium GO:0002009 333 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
single organism transport GO:0044765 206 0.032
regulation of protein transport GO:0051223 3 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
cellular amine metabolic process GO:0044106 2 0.031
phagocytosis GO:0006909 3 0.030
regulation of response to stimulus GO:0048583 269 0.030
biosynthetic process GO:0009058 294 0.029
protein localization to nucleus GO:0034504 3 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
positive regulation of catabolic process GO:0009896 4 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
cell morphogenesis GO:0000902 289 0.028
cell projection morphogenesis GO:0048858 244 0.028
cell part morphogenesis GO:0032990 246 0.028
cellular component biogenesis GO:0044085 178 0.027
organic substance biosynthetic process GO:1901576 289 0.027
cellular response to nutrient levels GO:0031669 2 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
cell substrate adhesion GO:0031589 4 0.027
regulation of mrna processing GO:0050684 3 0.027
organic cyclic compound metabolic process GO:1901360 301 0.026
positive regulation of cell adhesion GO:0045785 1 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
lateral inhibition GO:0046331 1 0.026
cellular carbohydrate metabolic process GO:0044262 4 0.026
regulation of signaling GO:0023051 235 0.026
organelle fusion GO:0048284 3 0.026
cellular response to starvation GO:0009267 1 0.026
regulation of cell shape GO:0008360 1 0.025
regulation of metabolic process GO:0019222 359 0.025
cellular protein catabolic process GO:0044257 4 0.025
exocytosis GO:0006887 1 0.025
stem cell proliferation GO:0072089 4 0.024
neuron projection development GO:0031175 180 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
neuron differentiation GO:0030182 353 0.024
cellular component assembly GO:0022607 170 0.024
regulation of cell communication GO:0010646 232 0.024
neuroblast proliferation GO:0007405 2 0.024
cellular component movement GO:0006928 335 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
locomotion GO:0040011 313 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
autophagy GO:0006914 4 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
heterocycle metabolic process GO:0046483 290 0.023
response to stress GO:0006950 263 0.023
head development GO:0060322 303 0.023
negative regulation of cellular process GO:0048523 283 0.023
regulation of signal transduction GO:0009966 225 0.023
gene expression GO:0010467 252 0.023
single organism metabolic process GO:0044710 217 0.023
tube morphogenesis GO:0035239 349 0.023
heart development GO:0007507 313 0.023
establishment of localization GO:0051234 244 0.023
single organism membrane fusion GO:0044801 2 0.023
post golgi vesicle mediated transport GO:0006892 1 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.022
localization of cell GO:0051674 244 0.022
digestive system development GO:0055123 289 0.022
single organism organelle organization GO:1902589 199 0.022
response to nutrient GO:0007584 3 0.022
cellular component morphogenesis GO:0032989 336 0.022
regulation of gene expression GO:0010468 265 0.022
embryonic organ development GO:0048568 381 0.022
regulation of binding GO:0051098 3 0.022
nuclear transport GO:0051169 4 0.022
cytokinesis GO:0000910 3 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
specification of symmetry GO:0009799 204 0.021
small molecule metabolic process GO:0044281 77 0.021
regulation of cytokine production GO:0001817 3 0.021
regulation of primary metabolic process GO:0080090 311 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
organelle organization GO:0006996 227 0.021
cell migration GO:0016477 237 0.021
immune system process GO:0002376 241 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
generation of neurons GO:0048699 385 0.021
regulation of cell activation GO:0050865 1 0.021
membrane fusion GO:0061025 2 0.021
positive regulation of secretion GO:0051047 1 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
rna metabolic process GO:0016070 219 0.021
positive regulation of cell activation GO:0050867 1 0.020
regulation of dna replication GO:0006275 3 0.020
transport GO:0006810 220 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
neuron development GO:0048666 262 0.020
cell motility GO:0048870 244 0.020
regulation of biological quality GO:0065008 263 0.020
protein metabolic process GO:0019538 183 0.020
negative regulation of biological process GO:0048519 304 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
cell matrix adhesion GO:0007160 4 0.020
endosomal transport GO:0016197 2 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
regulation of developmental process GO:0050793 247 0.020
macroautophagy GO:0016236 1 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
regulation of synapse organization GO:0050807 3 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
gland development GO:0048732 143 0.019
regulation of protein targeting GO:1903533 2 0.019
stem cell division GO:0017145 1 0.019
regulation of protein polymerization GO:0032271 2 0.019
lipid storage GO:0019915 1 0.019
protein import GO:0017038 3 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of synapse assembly GO:0051963 3 0.019
adult behavior GO:0030534 2 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
liver development GO:0001889 96 0.019
protein targeting to nucleus GO:0044744 3 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
nephron epithelium morphogenesis GO:0072088 1 0.019
female sex differentiation GO:0046660 4 0.018
protein polymerization GO:0051258 4 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
single organism localization GO:1902578 225 0.018
eye development GO:0001654 277 0.018
nuclear import GO:0051170 3 0.018
determination of bilateral symmetry GO:0009855 204 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
melanin metabolic process GO:0006582 2 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
rna biosynthetic process GO:0032774 181 0.018
single organism nuclear import GO:1902593 3 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cellular ketone metabolic process GO:0042180 11 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
nucleic acid metabolic process GO:0090304 244 0.017
response to wounding GO:0009611 116 0.017
mitochondrion organization GO:0007005 4 0.017
regulation of gtpase activity GO:0043087 2 0.017
locomotor rhythm GO:0045475 3 0.017
response to topologically incorrect protein GO:0035966 2 0.017
positive regulation of cell substrate adhesion GO:0010811 1 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
synaptic vesicle localization GO:0097479 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
vasculature development GO:0001944 278 0.017
phagocytosis engulfment GO:0006911 1 0.017
regulation of rna metabolic process GO:0051252 224 0.017
lamellipodium assembly GO:0030032 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
transcription dna templated GO:0006351 181 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
sensory organ development GO:0007423 393 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
protein secretion GO:0009306 1 0.017
regulation of reproductive process GO:2000241 4 0.017
response to external stimulus GO:0009605 264 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
regulation of inflammatory response GO:0050727 2 0.017
cellular component disassembly GO:0022411 1 0.017
secondary metabolic process GO:0019748 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
regionalization GO:0003002 274 0.017
cell cycle g1 s phase transition GO:0044843 1 0.016
cellular response to external stimulus GO:0071496 2 0.016
brain development GO:0007420 293 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of transcription dna templated GO:0006355 213 0.016
developmental growth GO:0048589 166 0.016
membrane invagination GO:0010324 1 0.016
regulation of protein catabolic process GO:0042176 1 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
positive regulation of biological process GO:0048518 253 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of cell projection assembly GO:0060491 4 0.016
digestive tract morphogenesis GO:0048546 231 0.016
organelle assembly GO:0070925 110 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
positive regulation of wound healing GO:0090303 1 0.015
blood vessel development GO:0001568 246 0.015
gastrulation GO:0007369 208 0.015
axon development GO:0061564 166 0.015
regulation of biosynthetic process GO:0009889 250 0.015
alcohol biosynthetic process GO:0046165 2 0.015
protein complex disassembly GO:0043241 1 0.015
leukocyte proliferation GO:0070661 1 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
response to organic substance GO:0010033 153 0.015
primary neural tube formation GO:0014020 1 0.015
oxoacid metabolic process GO:0043436 31 0.015
central nervous system development GO:0007417 387 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
meiotic nuclear division GO:0007126 4 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular localization GO:0051641 97 0.015
digestive tract development GO:0048565 265 0.015
angiogenesis GO:0001525 158 0.015
glucose homeostasis GO:0042593 1 0.015
cilium morphogenesis GO:0060271 85 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
protein dephosphorylation GO:0006470 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
regulation of exocytosis GO:0017157 1 0.014
cilium assembly GO:0042384 58 0.014
regulation of jak stat cascade GO:0046425 3 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
lamellipodium organization GO:0097581 1 0.014
synaptic vesicle transport GO:0048489 1 0.014
fertilization GO:0009566 3 0.014
spermatid development GO:0007286 2 0.014
blood vessel morphogenesis GO:0048514 216 0.014
cellular response to organic substance GO:0071310 105 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
centrosome organization GO:0051297 1 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
meiotic cell cycle process GO:1903046 3 0.014
positive regulation of exocytosis GO:0045921 1 0.014
response to carbohydrate GO:0009743 3 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
actin filament polymerization GO:0030041 2 0.014
growth GO:0040007 174 0.014
establishment of localization in cell GO:0051649 77 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
phosphorus metabolic process GO:0006793 109 0.013
axonogenesis GO:0007409 152 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of wound healing GO:0061041 2 0.013
ear development GO:0043583 127 0.013
nucleic acid templated transcription GO:0097659 181 0.013
regulation of organelle assembly GO:1902115 4 0.013
neuron projection morphogenesis GO:0048812 161 0.013
organic acid metabolic process GO:0006082 31 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
protein targeting to membrane GO:0006612 1 0.013
spermatid differentiation GO:0048515 2 0.013
rna localization GO:0006403 4 0.013
negative regulation of protein transport GO:0051224 3 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
regulation of circadian rhythm GO:0042752 4 0.013
regulation of cell differentiation GO:0045595 142 0.013
cognition GO:0050890 1 0.013
tube closure GO:0060606 1 0.013
forebrain cell migration GO:0021885 1 0.013
female gonad development GO:0008585 4 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
organic substance transport GO:0071702 58 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
negative regulation of catabolic process GO:0009895 3 0.013
recombinational repair GO:0000725 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
transmembrane transport GO:0055085 120 0.013
actin filament based movement GO:0030048 1 0.013
cellular biogenic amine metabolic process GO:0006576 2 0.012
homeostatic process GO:0042592 142 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
embryonic heart tube development GO:0035050 133 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
atp catabolic process GO:0006200 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
glycerophospholipid biosynthetic process GO:0046474 1 0.012
regulation of protein binding GO:0043393 3 0.012
macromolecular complex disassembly GO:0032984 1 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
negative regulation of defense response GO:0031348 2 0.012
sequestering of metal ion GO:0051238 3 0.012
pole plasm assembly GO:0007315 4 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
system process GO:0003008 185 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
negative regulation of metabolic process GO:0009892 86 0.012
hepaticobiliary system development GO:0061008 98 0.012
germ line stem cell maintenance GO:0030718 2 0.012
neurotransmitter transport GO:0006836 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
ameboidal type cell migration GO:0001667 143 0.012
determination of left right symmetry GO:0007368 179 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
chordate embryonic development GO:0043009 271 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
pigmentation GO:0043473 85 0.011
renal tubule morphogenesis GO:0061333 1 0.011
protein polyubiquitination GO:0000209 4 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
inner ear development GO:0048839 126 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
mitochondrial transport GO:0006839 2 0.011
cell substrate junction assembly GO:0007044 2 0.011
convergent extension GO:0060026 118 0.011
response to glucose GO:0009749 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
microtubule organizing center organization GO:0031023 1 0.011
organism emergence from protective structure GO:0071684 4 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
response to monosaccharide GO:0034284 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
muscle structure development GO:0061061 196 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
compound eye development GO:0048749 2 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
cellular amide metabolic process GO:0043603 4 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
mechanosensory behavior GO:0007638 2 0.011
intracellular signal transduction GO:0035556 85 0.011
positive regulation of immune effector process GO:0002699 3 0.011
heart looping GO:0001947 94 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
regulation of localization GO:0032879 104 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
energy reserve metabolic process GO:0006112 2 0.010
wound healing GO:0042060 90 0.010
protein modification process GO:0036211 100 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
sphingolipid biosynthetic process GO:0030148 2 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
macromolecule modification GO:0043412 111 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
sensory organ morphogenesis GO:0090596 200 0.010
nephron morphogenesis GO:0072028 2 0.010
membrane lipid biosynthetic process GO:0046467 2 0.010
cell projection assembly GO:0030031 64 0.010
response to hexose GO:0009746 3 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
peptide transport GO:0015833 1 0.010
pancreas development GO:0031016 84 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
dna templated transcription initiation GO:0006352 1 0.010
positive regulation of cell division GO:0051781 2 0.010

im:7147988 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.023
cardiovascular system disease DOID:1287 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
disease of metabolism DOID:0014667 0 0.010