Danio rerio

0 known processes

degs2

degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)

(Aliases: im:6909358)

degs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.075
head development GO:0060322 303 0.061
adult behavior GO:0030534 2 0.060
multicellular organism growth GO:0035264 4 0.052
cell migration GO:0016477 237 0.051
signal transduction GO:0007165 455 0.047
regulation of establishment of protein localization GO:0070201 4 0.046
single organism transport GO:0044765 206 0.044
exocytosis GO:0006887 1 0.043
positive regulation of transport GO:0051050 2 0.043
regulation of metabolic process GO:0019222 359 0.041
nitrogen compound metabolic process GO:0006807 319 0.039
response to stress GO:0006950 263 0.037
cellular component movement GO:0006928 335 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
aging GO:0007568 2 0.035
central nervous system development GO:0007417 387 0.035
cell motility GO:0048870 244 0.034
embryonic organ development GO:0048568 381 0.034
localization of cell GO:0051674 244 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
generation of neurons GO:0048699 385 0.033
organic acid metabolic process GO:0006082 31 0.032
nuclear transport GO:0051169 4 0.032
gtp metabolic process GO:0046039 4 0.031
immune system process GO:0002376 241 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.031
single fertilization GO:0007338 3 0.030
golgi vesicle transport GO:0048193 3 0.030
establishment of protein localization to plasma membrane GO:0090002 1 0.030
rna metabolic process GO:0016070 219 0.030
regulation of signal transduction GO:0009966 225 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of response to stimulus GO:0048583 269 0.028
small molecule metabolic process GO:0044281 77 0.028
meiotic nuclear division GO:0007126 4 0.028
maintenance of location GO:0051235 4 0.028
regulation of protein targeting GO:1903533 2 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
cell surface receptor signaling pathway GO:0007166 325 0.027
skeletal system development GO:0001501 181 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of protein transport GO:0051223 3 0.027
positive regulation of immune effector process GO:0002699 3 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
regulation of dendrite development GO:0050773 3 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
protein localization to nucleus GO:0034504 3 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
heterocycle metabolic process GO:0046483 290 0.026
cellular protein catabolic process GO:0044257 4 0.026
protein targeting to nucleus GO:0044744 3 0.026
response to chemical GO:0042221 320 0.026
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
germ line stem cell maintenance GO:0030718 2 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
ameboidal type cell migration GO:0001667 143 0.025
compound eye development GO:0048749 2 0.025
protein complex localization GO:0031503 1 0.025
actin polymerization or depolymerization GO:0008154 2 0.025
positive regulation of catabolic process GO:0009896 4 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
regulation of binding GO:0051098 3 0.024
transport GO:0006810 220 0.024
cellular component morphogenesis GO:0032989 336 0.024
regulation of protein catabolic process GO:0042176 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
mitochondrion organization GO:0007005 4 0.024
response to drug GO:0042493 3 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
regulation of signaling GO:0023051 235 0.024
positive regulation of biological process GO:0048518 253 0.023
developmental growth GO:0048589 166 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
positive regulation of secretion GO:0051047 1 0.023
sensory organ development GO:0007423 393 0.023
cellular ketone metabolic process GO:0042180 11 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.023
negative regulation of biological process GO:0048519 304 0.023
meiotic cell cycle process GO:1903046 3 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
fatty acid biosynthetic process GO:0006633 4 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
amine metabolic process GO:0009308 2 0.023
establishment of localization GO:0051234 244 0.022
protein import into nucleus GO:0006606 3 0.022
brain development GO:0007420 293 0.022
regulation of transcription dna templated GO:0006355 213 0.022
rna localization GO:0006403 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
atp catabolic process GO:0006200 4 0.022
multi organism cellular process GO:0044764 2 0.022
negative regulation of protein transport GO:0051224 3 0.021
phagocytosis GO:0006909 3 0.021
response to wounding GO:0009611 116 0.021
lipid storage GO:0019915 1 0.021
regulation of cell communication GO:0010646 232 0.021
protein polymerization GO:0051258 4 0.021
oxoacid metabolic process GO:0043436 31 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
cellular component disassembly GO:0022411 1 0.021
locomotion GO:0040011 313 0.021
single organism metabolic process GO:0044710 217 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
response to carbohydrate GO:0009743 3 0.020
regulation of wound healing GO:0061041 2 0.020
intracellular signal transduction GO:0035556 85 0.020
negative regulation of ras protein signal transduction GO:0046580 1 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
response to monosaccharide GO:0034284 3 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.020
regulation of protein complex assembly GO:0043254 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
regulation of cell activation GO:0050865 1 0.020
cellular response to biotic stimulus GO:0071216 3 0.019
gtp catabolic process GO:0006184 2 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
mesenchyme development GO:0060485 127 0.019
regulation of developmental process GO:0050793 247 0.019
dna templated transcription elongation GO:0006354 3 0.019
regulation of cytokine production GO:0001817 3 0.019
protein import GO:0017038 3 0.019
regulation of synapse organization GO:0050807 3 0.019
gene expression GO:0010467 252 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
nucleic acid templated transcription GO:0097659 181 0.018
membrane fusion GO:0061025 2 0.018
meiosis i GO:0007127 1 0.018
stem cell maintenance GO:0019827 4 0.018
regulation of primary metabolic process GO:0080090 311 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
response to external stimulus GO:0009605 264 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
chordate embryonic development GO:0043009 271 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
regulation of gene expression GO:0010468 265 0.018
cytokinesis GO:0000910 3 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
regulation of reproductive process GO:2000241 4 0.017
vasculature development GO:0001944 278 0.017
hemopoiesis GO:0030097 183 0.017
regulation of circadian rhythm GO:0042752 4 0.017
single organism nuclear import GO:1902593 3 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
erythrocyte differentiation GO:0030218 54 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
regulation of dna templated transcription elongation GO:0032784 3 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
pole plasm assembly GO:0007315 4 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
positive regulation of leukocyte mediated immunity GO:0002705 1 0.017
response to uv GO:0009411 3 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
fertilization GO:0009566 3 0.017
positive regulation of exocytosis GO:0045921 1 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
regulation of exocytosis GO:0017157 1 0.016
rna biosynthetic process GO:0032774 181 0.016
nucleic acid metabolic process GO:0090304 244 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
regulation of synapse assembly GO:0051963 3 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
inner ear development GO:0048839 126 0.016
wound healing GO:0042060 90 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
protein localization to plasma membrane GO:0072659 1 0.016
cognition GO:0050890 1 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
neuron differentiation GO:0030182 353 0.016
cellular response to external stimulus GO:0071496 2 0.016
system process GO:0003008 185 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
camera type eye development GO:0043010 222 0.015
peptidyl serine modification GO:0018209 2 0.015
immune system development GO:0002520 191 0.015
protein k48 linked ubiquitination GO:0070936 1 0.015
transcription dna templated GO:0006351 181 0.015
regulation of rna metabolic process GO:0051252 224 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
cellular biosynthetic process GO:0044249 286 0.015
apoptotic process involved in development GO:1902742 2 0.015
response to hexose GO:0009746 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
gland development GO:0048732 143 0.015
response to organic substance GO:0010033 153 0.015
nuclear import GO:0051170 3 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
myeloid leukocyte mediated immunity GO:0002444 1 0.015
cellular response to organic substance GO:0071310 105 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
positive regulation of cell cycle GO:0045787 3 0.015
eye development GO:0001654 277 0.015
organelle organization GO:0006996 227 0.015
catecholamine metabolic process GO:0006584 2 0.015
regulation of biological quality GO:0065008 263 0.015
tissue remodeling GO:0048771 4 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
cortical cytoskeleton organization GO:0030865 1 0.014
regulation of endocrine process GO:0044060 2 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
cellular response to oxygen levels GO:0071453 1 0.014
glucose import GO:0046323 2 0.014
positive regulation of epithelial cell migration GO:0010634 2 0.014
membrane invagination GO:0010324 1 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
angiogenesis GO:0001525 158 0.014
negative regulation of catabolic process GO:0009895 3 0.014
neutrophil mediated immunity GO:0002446 1 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
stem cell division GO:0017145 1 0.014
fin development GO:0033333 77 0.014
homeostatic process GO:0042592 142 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
blood vessel development GO:0001568 246 0.014
endosomal transport GO:0016197 2 0.014
single organism membrane fusion GO:0044801 2 0.014
organic substance biosynthetic process GO:1901576 289 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
autophagy GO:0006914 4 0.014
biosynthetic process GO:0009058 294 0.014
startle response GO:0001964 4 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of blood pressure GO:0008217 1 0.014
intracellular mrna localization GO:0008298 1 0.013
regulation of autophagy GO:0010506 3 0.013
locomotor rhythm GO:0045475 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
rna modification GO:0009451 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
heart development GO:0007507 313 0.013
establishment of rna localization GO:0051236 3 0.013
phagocytosis engulfment GO:0006911 1 0.013
cytoplasm organization GO:0007028 4 0.013
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.013
regulation of protein binding GO:0043393 3 0.013
cell projection organization GO:0030030 284 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
stem cell proliferation GO:0072089 4 0.013
cell cell recognition GO:0009988 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of protein localization to plasma membrane GO:1903076 1 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
positive regulation of cytokine production GO:0001819 2 0.013
forebrain development GO:0030900 96 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
embryonic skeletal system development GO:0048706 97 0.013
mitochondrial transport GO:0006839 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.012
dna templated transcription initiation GO:0006352 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cell part morphogenesis GO:0032990 246 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
muscle organ development GO:0007517 101 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
regulation of oocyte development GO:0060281 3 0.012
cellular response to hypoxia GO:0071456 1 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
response to vitamin GO:0033273 3 0.012
response to biotic stimulus GO:0009607 97 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
single organism localization GO:1902578 225 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
eye morphogenesis GO:0048592 144 0.012
regulation of cell shape GO:0008360 1 0.012
lateral inhibition GO:0046331 1 0.012
growth GO:0040007 174 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
embryonic heart tube development GO:0035050 133 0.012
ear development GO:0043583 127 0.012
peptide transport GO:0015833 1 0.012
hepaticobiliary system development GO:0061008 98 0.012
neuron development GO:0048666 262 0.012
developmental programmed cell death GO:0010623 4 0.012
nucleic acid transport GO:0050657 2 0.012
nuclear export GO:0051168 1 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
cytoskeleton organization GO:0007010 96 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
leukocyte proliferation GO:0070661 1 0.012
cell proliferation GO:0008283 80 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
protein metabolic process GO:0019538 183 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
convergent extension GO:0060026 118 0.012
regulation of organ growth GO:0046620 3 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of metal ion transport GO:0010959 4 0.012
digestive system development GO:0055123 289 0.012
female sex differentiation GO:0046660 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
gastrulation GO:0007369 208 0.012
inositol lipid mediated signaling GO:0048017 2 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
skeletal system morphogenesis GO:0048705 102 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
tube morphogenesis GO:0035239 349 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
protein secretion GO:0009306 1 0.011
protein complex disassembly GO:0043241 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
regeneration GO:0031099 91 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
central nervous system myelin formation GO:0032289 1 0.011
regulation of jak stat cascade GO:0046425 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
regulation of gtpase activity GO:0043087 2 0.011
chemosensory behavior GO:0007635 1 0.011
single organism organelle organization GO:1902589 199 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
stem cell differentiation GO:0048863 117 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
response to antibiotic GO:0046677 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
adherens junction organization GO:0034332 4 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
neurotransmitter transport GO:0006836 2 0.011
establishment of localization in cell GO:0051649 77 0.011
regulation of inflammatory response GO:0050727 2 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
apoptotic process GO:0006915 116 0.011
multicellular organismal response to stress GO:0033555 2 0.011
positive regulation of striated muscle tissue development GO:0045844 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of cell death GO:0010941 103 0.011
wnt signaling pathway GO:0016055 80 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
response to glucose GO:0009749 3 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
negative regulation of cytokine production GO:0001818 1 0.010
specification of symmetry GO:0009799 204 0.010
regulation of localization GO:0032879 104 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
nucleobase containing compound transport GO:0015931 2 0.010
positive regulation of metabolic process GO:0009893 108 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
negative regulation of signal transduction GO:0009968 94 0.010
digestive tract morphogenesis GO:0048546 231 0.010
specification of axis polarity GO:0065001 4 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
rna transport GO:0050658 2 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010

degs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of metabolism DOID:0014667 0 0.014
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.011