Danio rerio

0 known processes

cyp2k18

cytochrome P450, family 2, subfamily K, polypeptide 18

(Aliases: zgc:66268,MGC66268)

cyp2k18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound metabolic process GO:1901360 301 0.086
Zebrafish
regulation of biological quality GO:0065008 263 0.064
Worm
regulation of mrna splicing via spliceosome GO:0048024 3 0.064
organonitrogen compound metabolic process GO:1901564 74 0.059
phagocytosis GO:0006909 3 0.059
lipid storage GO:0019915 1 0.055
Worm
larval development GO:0002164 2 0.055
nitrogen compound metabolic process GO:0006807 319 0.054
maintenance of location GO:0051235 4 0.053
Worm
multicellular organism growth GO:0035264 4 0.050
aging GO:0007568 2 0.048
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.047
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.047
single organism metabolic process GO:0044710 217 0.046
Zebrafish
response to external stimulus GO:0009605 264 0.046
morphogenesis of an epithelium GO:0002009 333 0.045
rna metabolic process GO:0016070 219 0.042
response to corticosteroid GO:0031960 1 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
small molecule metabolic process GO:0044281 77 0.040
Zebrafish
amine metabolic process GO:0009308 2 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
cellular amine metabolic process GO:0044106 2 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
cellular component assembly GO:0022607 170 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
tube morphogenesis GO:0035239 349 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
meiotic nuclear division GO:0007126 4 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
gene expression GO:0010467 252 0.032
lipid metabolic process GO:0006629 52 0.032
meiotic chromosome segregation GO:0045132 3 0.032
heterocycle metabolic process GO:0046483 290 0.031
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.031
positive regulation of transport GO:0051050 2 0.031
regulation of cell communication GO:0010646 232 0.031
nucleic acid metabolic process GO:0090304 244 0.030
stem cell proliferation GO:0072089 4 0.030
response to external biotic stimulus GO:0043207 97 0.029
epithelial cell differentiation GO:0030855 116 0.029
cellular macromolecule metabolic process GO:0044260 391 0.028
regulation of metabolic process GO:0019222 359 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
digestive system development GO:0055123 289 0.027
regulation of protein transport GO:0051223 3 0.027
regulation of gene expression GO:0010468 265 0.027
cellular component biogenesis GO:0044085 178 0.027
organic acid metabolic process GO:0006082 31 0.027
ether metabolic process GO:0018904 1 0.027
Zebrafish
response to drug GO:0042493 3 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of signaling GO:0023051 235 0.026
single organism localization GO:1902578 225 0.026
response to chemical GO:0042221 320 0.026
Worm
regulation of establishment of protein localization GO:0070201 4 0.026
sensory perception of chemical stimulus GO:0007606 3 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
stem cell maintenance GO:0019827 4 0.025
determination of bilateral symmetry GO:0009855 204 0.025
regulation of rna metabolic process GO:0051252 224 0.025
regulation of binding GO:0051098 3 0.025
response to other organism GO:0051707 97 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
tissue remodeling GO:0048771 4 0.024
heart development GO:0007507 313 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
regulation of cytokine production GO:0001817 3 0.024
regulation of protein complex assembly GO:0043254 3 0.023
regulation of response to stimulus GO:0048583 269 0.023
regulation of signal transduction GO:0009966 225 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
gland development GO:0048732 143 0.023
oxoacid metabolic process GO:0043436 31 0.023
immune system development GO:0002520 191 0.023
regulation of primary metabolic process GO:0080090 311 0.023
regulation of developmental process GO:0050793 247 0.022
synaptic target recognition GO:0008039 1 0.022
digestive tract development GO:0048565 265 0.022
negative regulation of biological process GO:0048519 304 0.022
regulation of inflammatory response GO:0050727 2 0.022
regulation of blood pressure GO:0008217 1 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
response to biotic stimulus GO:0009607 97 0.022
transport GO:0006810 220 0.022
hemopoiesis GO:0030097 183 0.022
response to vitamin GO:0033273 3 0.022
regulation of mrna processing GO:0050684 3 0.021
embryonic organ development GO:0048568 381 0.021
response to monosaccharide GO:0034284 3 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
single organism organelle organization GO:1902589 199 0.021
secondary metabolic process GO:0019748 3 0.021
Zebrafish
meiotic cell cycle process GO:1903046 3 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
homeostatic process GO:0042592 142 0.020
single organism transport GO:0044765 206 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
cellular protein catabolic process GO:0044257 4 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
specification of symmetry GO:0009799 204 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
negative regulation of secretion GO:0051048 2 0.020
nuclear transport GO:0051169 4 0.020
regulation of dna replication GO:0006275 3 0.020
response to carbohydrate GO:0009743 3 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
spermatid differentiation GO:0048515 2 0.019
response to hexose GO:0009746 3 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
nuclear import GO:0051170 3 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
organic substance biosynthetic process GO:1901576 289 0.018
small molecule catabolic process GO:0044282 3 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
organism emergence from protective structure GO:0071684 4 0.018
protein localization to nucleus GO:0034504 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
nucleic acid templated transcription GO:0097659 181 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
renal tubule morphogenesis GO:0061333 1 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
phagocytosis engulfment GO:0006911 1 0.017
aflatoxin metabolic process GO:0046222 1 0.017
Zebrafish
protein import into nucleus GO:0006606 3 0.017
membrane invagination GO:0010324 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
signal transduction GO:0007165 455 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
organelle organization GO:0006996 227 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
protein targeting to nucleus GO:0044744 3 0.017
system process GO:0003008 185 0.017
response to stress GO:0006950 263 0.017
Worm
protein homooligomerization GO:0051260 3 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
translational initiation GO:0006413 3 0.017
generation of neurons GO:0048699 385 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
oocyte maturation GO:0001556 4 0.017
interspecies interaction between organisms GO:0044419 4 0.017
response to glucocorticoid GO:0051384 1 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
actin filament based process GO:0030029 64 0.016
protein secretion GO:0009306 1 0.016
positive regulation of cytokine production GO:0001819 2 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of cell activation GO:0050865 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
establishment of localization GO:0051234 244 0.016
neuron differentiation GO:0030182 353 0.016
peptidyl serine modification GO:0018209 2 0.016
blood circulation GO:0008015 87 0.016
response to topologically incorrect protein GO:0035966 2 0.016
protein import GO:0017038 3 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
positive regulation of metabolic process GO:0009893 108 0.016
response to bacterium GO:0009617 58 0.015
cellular ketone metabolic process GO:0042180 11 0.015
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 3 0.015
microtubule organizing center organization GO:0031023 1 0.015
cognition GO:0050890 1 0.015
immune system process GO:0002376 241 0.015
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cellular component disassembly GO:0022411 1 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
gastrulation GO:0007369 208 0.015
cellular response to external stimulus GO:0071496 2 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
Worm
tissue regeneration GO:0042246 74 0.015
regulation of protein catabolic process GO:0042176 1 0.015
xenobiotic metabolic process GO:0006805 4 0.015
gtp catabolic process GO:0006184 2 0.015
angiogenesis GO:0001525 158 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
apical junction assembly GO:0043297 1 0.014
regulation of cellular component organization GO:0051128 86 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
chordate embryonic development GO:0043009 271 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
biosynthetic process GO:0009058 294 0.014
spindle assembly GO:0051225 2 0.014
positive regulation of cell activation GO:0050867 1 0.014
positive regulation of secretion GO:0051047 1 0.014
hormone transport GO:0009914 2 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
single organism nuclear import GO:1902593 3 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
muscle structure development GO:0061061 196 0.014
atp catabolic process GO:0006200 4 0.014
central nervous system development GO:0007417 387 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of protein binding GO:0043393 3 0.013
response to wounding GO:0009611 116 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
vasculature development GO:0001944 278 0.013
heart morphogenesis GO:0003007 156 0.013
female meiotic division GO:0007143 2 0.013
protein acylation GO:0043543 3 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
positive regulation of cell cycle GO:0045787 3 0.013
urogenital system development GO:0001655 97 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
cellular response to organic substance GO:0071310 105 0.013
leukocyte proliferation GO:0070661 1 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
multi organism process GO:0051704 134 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
negative regulation of transcription dna templated GO:0045892 45 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
hepaticobiliary system development GO:0061008 98 0.013
dna templated transcription elongation GO:0006354 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
response to glucose GO:0009749 3 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
pancreas development GO:0031016 84 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
establishment of rna localization GO:0051236 3 0.012
regulation of biosynthetic process GO:0009889 250 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
positive regulation of biological process GO:0048518 253 0.012
lymphocyte proliferation GO:0046651 1 0.012
neuroblast proliferation GO:0007405 2 0.012
kidney development GO:0001822 92 0.012
gtp metabolic process GO:0046039 4 0.012
macromolecule localization GO:0033036 54 0.012
Worm
rna biosynthetic process GO:0032774 181 0.012
protein complex disassembly GO:0043241 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
cellular response to nutrient levels GO:0031669 2 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
cellular hormone metabolic process GO:0034754 19 0.012
negative regulation of nuclear division GO:0051784 3 0.012
lipid catabolic process GO:0016042 4 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
regulation of cell shape GO:0008360 1 0.012
response to nutrient GO:0007584 3 0.012
negative regulation of defense response GO:0031348 2 0.012
lipid homeostasis GO:0055088 3 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of hormone secretion GO:0046883 2 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
protein acetylation GO:0006473 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
mitochondrion organization GO:0007005 4 0.012
protein polymerization GO:0051258 4 0.012
cellular response to unfolded protein GO:0034620 2 0.012
response to lipid GO:0033993 60 0.012
stem cell division GO:0017145 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
response to organic substance GO:0010033 153 0.012
monoamine transport GO:0015844 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
hatching GO:0035188 4 0.012
organic heteropentacyclic compound metabolic process GO:1901376 1 0.012
Zebrafish
cellular response to topologically incorrect protein GO:0035967 2 0.011
female gonad development GO:0008585 4 0.011
determination of left right symmetry GO:0007368 179 0.011
dna templated transcription initiation GO:0006352 1 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
outflow tract morphogenesis GO:0003151 1 0.011
mononuclear cell proliferation GO:0032943 1 0.011
lamellipodium organization GO:0097581 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
response to uv GO:0009411 3 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
cell aging GO:0007569 2 0.011
rna modification GO:0009451 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regionalization GO:0003002 274 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
endocardial cushion morphogenesis GO:0003203 3 0.011
proepicardium development GO:0003342 4 0.011
positive regulation of translation GO:0045727 1 0.011
regulation of reproductive process GO:2000241 4 0.011
ion transport GO:0006811 114 0.011
regulation of cell death GO:0010941 103 0.011
ameboidal type cell migration GO:0001667 143 0.011
endosomal transport GO:0016197 2 0.011
catabolic process GO:0009056 32 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
cellular response to starvation GO:0009267 1 0.011
negative regulation of immune response GO:0050777 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
positive regulation of cellular process GO:0048522 201 0.011
embryonic organ morphogenesis GO:0048562 274 0.010
regulation of tube size GO:0035150 2 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.010
determination of dorsal ventral asymmetry GO:0048262 34 0.010
macromolecule deacylation GO:0098732 3 0.010
cellular component morphogenesis GO:0032989 336 0.010
antimicrobial humoral response GO:0019730 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
nephron morphogenesis GO:0072028 2 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
response to cold GO:0009409 4 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
cellular lipid metabolic process GO:0044255 36 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
aflatoxin b1 metabolic process GO:0043390 1 0.010
Zebrafish
b cell activation GO:0042113 2 0.010
apoptotic process involved in development GO:1902742 2 0.010
autophagy GO:0006914 4 0.010
cell morphogenesis GO:0000902 289 0.010
localization of cell GO:0051674 244 0.010
positive regulation of immune effector process GO:0002699 3 0.010

cyp2k18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
musculoskeletal system disease DOID:17 0 0.027
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
muscular disease DOID:0080000 0 0.016
maturity onset diabetes of the young DOID:0050524 0 0.010